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( Zhi Hua Shen ),( Ya Feng Xia ) 경남대학교 극동문제연구소 2013 ASIAN PERSPECTIVE Vol.37 No.1
The contested Sino-Korean border issue has received very little study. Making use of presently available sources in the several different archives in China and Taiwan, as well as documents made public in South Korea, we examine in this article the historical background of the Sino-Korean border issue and border relations from 1950 to 1964. North Korea was dissatisfied with the Jiandao Treaty of 1909, but was uneasy about raising that dissatisfaction with the Chinese in the 1950s. When China was caught in a number of woeful domestic and international predicaments in 1962, Pyongyang seized the opportunity and proposed to Beijing that the border issue be settled. It took the two sides only six months to negotiate and sign a new boundary treaty. As a result, North Korea emerged with a larger share of Tianchi and other disputed areas.
( Shen Zhi Hua ),( Ya Feng Xia ) 경남대학교 극동문제연구소 2011 ASIAN PERSPECTIVE Vol.35 No.2
Previous studies of the Korean War have given much attention to the armistice negotiations that started in July 1951. Little has been written of the peacemaking efforts between the time of China`s entry into the war in October 1950 and the creation of the United Nations cease-fire resolution in early January 1951. Relying on Chinese, Russian, and US archival sources, in particular Mao Zedong`s recently published military papers and Chinese foreign ministry archives, this article examines China`s views and policies toward the UN resolution. It argues that Mao made an erroneous decision not to accept the UN resolution in January 1951. Because of the mistake, China completely lost its advantage on the Korean battlefield and in the international arena.
극동에서 소련의 전략적 이익보장: 한국전쟁의 기원과 스탈린의 정책결정 동기
션즈화 ( Zhi Hua Shen ) 경남대학교 극동문제연구소 2014 한국과 국제정치 Vol.30 No.2
스탈린은 1949년 말까지도 북한이 무력을 사용하여 한반도 통일을 실현하는 것을 극력 저지했으나, 1950년 1월 말 갑자기 태도를 바꾸어 김일성의 주장을 적극 지지했다. 미국의 한반도전쟁에의 간섭 여부는 전쟁을 결정하는 조건이었을 뿐, 미국의 개입 유도 자체가 목적은 아니었다. 미국의 관심을 동아시아로 끌어들인 것은 전쟁의 결과였지, 결코 한국전쟁을 결정한 동기가 아니었다. 또한 아시아혁명을 고무하고 촉진하는 것 역시 일종의 표면적 현상이었을 뿐 소련 외교전략의 전환은 아니었다. 1950년 중소우호동맹상호원조조약의 체결로 인해 소련은 태평양으로 향하는 유일한 항구와 부동항을 상실했고, 이것은 의심할 것 없이 중대한 전략적 이익의 손실이었다. 그 결과 소련은 아시아에서 전략상 거점을 상실하게 되었다. 결국 스탈린이 김일성의 전쟁 개시에 동의했던 것은 그 승패 여부와 관계없이, 그가 극동에서 설정했던 소련의 전략목표를 보장할 수 있었기 때문이다. By the end of 1949 Stalin had used every conceivable stratagem in order to prevent North Korea from launching a war for unification against South Korea. But by late January 1950, Stalin suddenly had a change of mind and decided to wholeheartedly support Kim Il-sung to achieve his goal. Whether or not the United States would intervene was only a precondition, not the end. To draw U.S.`s attention to the Far East was the end result, but not the motive. And to encourage and promote Asian revolution was only the superficial phenomenon, but not the shift in Soviet`s diplomatic strategy. The signing of the Sino-Soviet alliance treaty in 1950 meant that the Soviet Union would lose its only exit to the Pacific Ocean and warm-water port. Without doubt, this would cause great loss to Soviet`s strategic interests. As a result, the Soviet Union would lose its strategic backing in Asia. The reason why Stalin decided to support Kim Il-sung`s attack on South Korea was that he hoped to regain or safeguard Soviet`s tradition strategic prop in the Far East through this military action. No matter what the outcome might be, the military conflict in the Korean peninsula would guarantee Soviet`s strategic aim as designed by Stalin.
Zhi Ma,Chung-Bang Yun,Yan-Bin Shen,Feng Yu,Hua-Ping Wan,Yao-Zhi Luo 국제구조공학회 2019 Smart Structures and Systems, An International Jou Vol.24 No.4
A Bayesian dynamic linear model (BDLM) is presented for a data-driven analysis for response prediction and load effect separation of a revolving auditorium structure, where the main loads are self-weight and dead loads, temperature load, and audience load. Analyses are carried out based on the long-term monitoring data for static strains on several key members of the structure. Three improvements are introduced to the ordinary regression BDLM, which are a classificatory regression term to address the temporary audience load effect, improved inference for the variance of observation noise to be updated continuously, and component discount factors for effective load effect separation. The effects of those improvements are evaluated regarding the root mean square errors, standard deviations, and 95% confidence intervals of the predictions. Bayes factors are used for evaluating the probability distributions of the predictions, which are essential to structural condition assessments, such as outlier identification and reliability analysis. The performance of the present BDLM has been successfully verified based on the simulated data and the real data obtained from the structural health monitoring system installed on the revolving structure.
β3GnT8 Regulates Laryngeal Carcinoma Cell Proliferation Via Targeting MMPs/TIMPs and TGF-β1
Hua, Dong,Qin, Fang,Shen, Li,Jiang, Zhi,Zou, Shi-Tao,Xu, Lan,Cheng, Zhi-Hong,Wu, Shi-Liang Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5
Previous evidence showed ${\beta}1$, 3-N-acetylglucosaminyltransferase 8 (${\beta}3GnT8$), which can extend polylactosamine on N-glycans, to be highly expressed in some cancer cell lines and tissues, indicating roles in tumorigenesis. However, so far, the function of ${\beta}3GnT8$ in laryngeal carcinoma has not been characterized. To test any contribution, Hep-2 cells were stably transfected with sense or interference vectors to establish cell lines that overexpressed or were deficient in ${\beta}3GnT8$. Here we showed that cell proliferation was increased in ${\beta}3GnT8$ overexpressed cells but decreased in ${\beta}3GnT8$ knockdown cells using MTT. Furthermore, we demonstrated that change in ${\beta}3GnT8$ expression had significant effects on tumor growth in nude mice.We further provided data suggesting that overexpression of ${\beta}3GnT8$ enhanced the expression of matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) at both the mRNA and protein levels, associated with shedding of tissue inhibitors of metalloproteinase TIMP-2. In addition, it caused increased production of transforming growth factor beta 1 (TGF-${\beta}1$), whereas ${\beta}3GnT8$ gene knockdown caused the reverse effect. The results may indicate a novel mechanism by which effects of ${\beta}3GnT8$ in regulating cellular proliferation are mediated, at least in partvia targeting MMPs/TIMPs and TGF-${\beta}1$ in laryngeal carcinoma Hep-2 cells. The finding may lay a foundation for further investigations into the ${\beta}3GnT8$ as a potential target for therapy of laryngeal carcinoma.
Che, Yan-Hua,You, Jing,Chongsuvivatwong, Virasakdi,Li, Li,Sriplung, Hucha,Yan, Yuan-Zhi,Ma, Si-Jia,Zhang, Xiaoli,Shen, Ting,Chen, He-Min,Rao, Shao-Feng,Zhang, Ru-Yi Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.12
Background: Patients with chronic liver diseases (CLD) may have compromised health related quality of life (HRQoL). Hepatitis B virus (HBV) infection has long been the leading cause of CLD including liver cancer and cirrhosis. Knowledge on different symptom profiles of CLD should help in development of comprehensive treatment and patient care plans. Objective: To access the facets of HRQoL in chronic liver diseases throughout their spectrum of severity. Materials and Methods: A cross-sectional study was conducted in the First Affiliated Hospital of Kunming Medical University in Yunnan Province of China. Both out- and inpatients undergoing treatment protocols for different HBV related liver disease states were consecutively collected from December 2012 to June 2013. ANOVA was used to compare the mean scores of EQ-5D and chronic liver disease questionnaire (CLDQ) among 5 disease groups. The relationship between demographic variables predicting global CLDQ scores and the domains of CLDQ was analysed. Results: A total of 1040 patients including 520 without complications, 91 with compensated cirrhosis, 198 with decompensated cirrhosis, 131 with HCC and 100 with liver failure were recruited. All domains of CLDQ, the means of EQ-5D value and EQ VAS exhibited significant decline with worsening of disease severity from uncomplicated HBV to liver failure. The multivariate regression demonstrated the reduction of mean scores of CLDQ domain at advanced stage. Patients with liver failure and HCC had more HRQoL impairment than other disease states. No effect of patient gender was found. Patient age was associated with 'fatigue' and 'worry' domains (p=0.006; p=0.004) but not with other domains and global scores of CLDQ and ED-5D. Conclusions: The HRQoL in chronic hepatitis B patients is greatly affected by disease states. Care for HBV-related diseases should consider not only the outcomes of treatment strategies but also improvement in patient wellbeing.
Sorption kinetics of sulphate ions on quaternary ammonium-modified rice straw
Wei Cao,Zhi Dang,Bao-Ling Yuan,Chun-Hua Shen,Jin Kan,Xiu-Ling Xue 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.4
Batch sorption experiments with variable concentration of sulphate and temperature were conducted to investigate sorption kinetics of sulphate ions on quaternary ammonium-modified rice straw (QMRS). Kinetic data were discussed with pseudo first- and second-order rate equations and diffusion models. The results showed the sorption equilibrium time is about 20 min and the activated energy Ea is 19.3 kJ/mol. Increase of temperature and initial sulphate concentration favored sorption process. The sorption kinetics followed pseudo second-order rate equation, and the overall rate was determined by film diffusion. Additionally, characterization by 13C NMR and EDS confirmed the presence of quaternary ammonium groups in QMRS.
Historical Long-term Exposure to Pentachlorophenol Causing Risk of Cancer - A Community Study
Zheng, Rui-Zhi,Zhang, Qing-He,He, Yi-Xin,Zhang, Qian,Yang, Lin-Shen,Zhang, Zhi-Hua,Zhang, Xiu-Jun,Hu, Jing-Ting,Huang, Fen Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2
Background: Pervious studies suggested occupational workers exposure to pentachlorophenol (PCP) might contribute to increased risk of cancer. However, few studies have focused on associations between PCP and cancer risk at the community level. Objective: The present study was to explore the cancer risk for the community population living long-term in a PCP contaminated area. Methods: All the cancer cases diagnosed in 2009-2011 in Tongling City were collected. The cancer patients' residencies were geo-referenced in each district. The historical PCP usage for each district of Tongling was calculated as the PCP pollution index, which was further used to divide into PCP exposure categories. Standardized rate ratios (SRRs) of cancer incidence were applied to detect the cancer risk as exposure grade elevated. Correlation analysis was performed to analyze the relationship between PCP pollution and cancer incidence. Results: A total of 5,288 cancer cases (3,451 male and 1,837 female) were identified. PCP usage was correlated with the incidence of leukemia (r=0.88, P=0.002) for males, and with cancer of the esophagus for males (r=0.83, P=0.008) and females (r=0.71, P=0.020). Compared with the low exposure category, significant SRRs for total cancer sites was obtained for high PCP exposure category (SRR=1.61, 95%CI=1.59-1.62). Most SRR values of the cancer sites were significantly increased as exposure grade elevated and exposure time extended. Conclusion: The present study found that community residents living in the PCP contaminated area had increased risk of cancers. Leukemias, lymphomas and nasopharyngeal and esophageal cancers are most possibly associated with PCP exposure.
Ji Cheng Zhang,Jin Hua Wang,Jun Yi Liu,Qi Wei Guo,Jia Lin,Yi Lin Shen,Ke Xin Jia,Jia Jing Cai,Guo Ming Su,Ding Zhi Fang 대한신경정신의학회 2023 PSYCHIATRY INVESTIGATION Vol.20 No.11
Objective To verify effects of rs1061622 at tumor necrosis factor-α receptor II (TNF-RII) gene (<i>TNF-RII</i>) on post-traumatic stress disorder (PTSD) and its interactive effects with PTSD on serum lipids levels in adolescents.Methods PTSD was measured by PTSD Checklist-Civilian Version (PCL-C) in 699 adolescent survivors at 6 months after Wenchuan earthquake in China. A polymerase chain reaction and restriction fragment length polymorphism assay were utilized for <i>TNF-RII</i> rs1061622 genotyping followed by verification using DNA sequencing. Serum triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol were tested using routine methods.Results G (deoxyguanine) allele carriers had higher PCL-C scores than TT (deoxythymidine) homozygotes in female subjects. Female adolescents had higher PCL-C scores than male subjects in TT homozygotes. Predictors of PTSD prevalence and severity were different between G allele carriers and TT homozygotes. Subjects with PTSD had lower TG, TG/HDL-C, TC/HDL-C, and higher HDL-C than adolescents without PTSD in male G allele carriers. G allele carriers had higher TG/HDL-C and TC/HDL-C than TT homozygotes in male adolescents without PTSD, and lower TG and TG/HDL-C in male PTSD patients. G allele carriers had higher TG than TT homozygotes only in female adolescents without PTSD.Conclusion These results suggest reciprocal actions of <i>TNF-RII</i> rs1061622 with other factors on PTSD severity, interplays of <i>TNF-RII</i> rs1061622 with PTSD on serum lipid levels, and novel treatment strategies for PTSD and comorbidities of PTSD with hyperlipidemia among adolescents with different genetic backgrounds of <i>TNF-RII</i> rs1061622 after experiencing traumatic events.
Zhou, Qing-Xiang,Shen, Xing-Jia,Yi, Yong-Zhu,Xia, Ai-Hua,Zhang, Zhi-Fang Korean Society of Sericultural Science 2006 International Journal of Industrial Entomology Vol.13 No.2
We successfully extirpated all four hemopoietic organ-wing disc complexes of the fifth instar larvae of Bombyx mori, and found that most of the treated silkworms could still develop into the moths. We investigated the changes of the circulating hemocytes and evaluated the effects of extirpation on the hemopoiesis. The results showed that proliferation of circulating hemocytes was sufficient to allow development of the silkworms which complexes were totally extirpated. We also found that hemopoietic organ-wing disc complexes extirpation might cause a certain hemopoietic compensation of the remainder complexes during early spinning. Exogenous hormones such as $20-{\beta}-hydroxyecdysone$ and juvenile hormone analog had a positive effect on hemocytes proliferation.