Tight sportswear and physiological function-Effect on muscle strength and EMG activity-

( Xiao Qun Dai ),( Yu Ping Li ),( Juan Juan Cai ),( A Ming Lu ),( Guo Dong Wang ) 복식문화학회 2013 服飾文化硏究 Vol.21 No.4

It has been reported that tight sportswear could have complicated influence on physiological function of human body. The purpose of this present study was to investigate the effect of wearing gradient compression tights (GCT) on muscle strength and EMG activity during repeated isokinetic muscle contractions. Four healthy male undergraduate students performed maximal voluntary isokinetic concentric muscle contractions on biomechanical test and training systems with GCT and loose pants as control (Cont) respectively. During each test, the peak torque of extensor and flexor contractions and the surface electromyography (sEMG) of the recrus femoris and medial gastrocnemius was recorded simultaneously, the peak torque was recorded as an indicator of muscle strength, and the average amplitude and mean power frequency of sEMO were calculated as indicators of EMG activity. The results showed that: the peak torque decreased gradually during continuous muscle contractions both when the Cont and GCT were worn. average sEMG and mean power frequency declined along with the repetitions of muscle contractions for both wearing conditions, and the change tendency was consistence with that of peak torque. There was no obvious, difference between the peak torque recorded wearing the Cont or wearing GCT, but when GCT were worn, average sEMG was lower and mean power frequency was higher than the Cont condition. In 24 samples obtained from four subjects, 80% of results showed the same trend. So we could make a conclusion that wearing ocr had no obvious effect on the improvement of muscle strength, but it would affect the EMO activity posiuvly.

Tight sportswear and physiological function - Effect on muscle strength and EMG activity -

Dai, Xiao-Qun,Li, Yu-Ping,Cai, Juan-Juan,Lu, A-Ming,Wang, Guo-Dong The Costume Culture Association 2013 服飾文化硏究 Vol.21 No.4

It has been reported that tight sportswear could have complicated influence on physiological function of human body. The purpose of this present study was to investigate the effect of wearing gradient compression tights (GCT) on muscle strength and EMG activity during repeated isokinetic muscle contractions. Four healthy male undergraduate students performed maximal voluntary isokinetic concentric muscle contractions on biomechanical test and training systems with GCT and loose pants as control (Cont) respectively. During each test, the peak torque of extensor and flexor contractions and the surface electromyography (sEMG) of the rectus femoris and medial gastrocnemius was recorded simultaneously, the peak torque was recorded as an indicator of muscle strength, and the average amplitude and mean power frequency of sEMG were calculated as indicators of EMG activity. The results showed that: the peak torque decreased gradually during continuous muscle contractions both when the Cont and GCT were worn, average sEMG and mean power frequency declined along with the repetitions of muscle contractions for both wearing conditions, and the change tendency was consistence with that of peak torque. There was no obvious difference between the peak torque recorded wearing the Cont or wearing GCT, but when GCT were worn, average sEMG was lower and mean power frequency was higher than the Cont condition. In 24 samples obtained from four subjects, 80% of results showed the same trend. So we could make a conclusion that wearing GCT had no obvious effect on the improvement of muscle strength, but it would affect the EMG activity positivly.

Tight sportswear and physiological function-Effect on muscle strength and EMG activity-

Xiao Qun Dai,Yu Ping Li,Juan Juan Cai,A Ming Lu,Guo Dong Wang 복식문화학회 2013 服飾文化硏究 Vol.21 No.4

Protective Effects of Scutellaria barbata Against Rat Liver Tumorigenesis

Dai, Zhi-Jun,Wu, Wen-Ying,Kang, Hua-Feng,Ma, Xiao-Bin,Zhang, Shu-Qun,Min, Wei-Li,Lu, Wang-Feng,Lin, Shuai,Wang, Xi-Jing Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1

Scutellaria barbata D. Don (S. barbata), a traditional Chinese medicine, is used to treat cancers, inflammation, and urinary diseases. This study aimed to determine any protective effects of S. barbata crude extract (CE-SB) against rat liver tumorigenesis induced by diethylnitrosamine (DENA). Liver malfunction indices in serum were measured by biochemical examination. Hematoxylin and eosin staining was performed to examine liver pathology. Contents of malondialdehyde (MDA) and superoxide dismutase (SOD) were measured in liver homogenates to evaluate oxidative stress. The levels of liver malfunction indices in the CE-SB groups, especially in the CE-SB high dose group, were lower than that of the model group (P<0.05). The results from histological examination indicated that the number of liver nodules in the CE-SB groups decreased compared with the model group (P<0.05). Content of MDA determined in liver was significantly decreased, and level of SOD elevated by CE-SB. CE-SB can inhibit experimental liver tumorigenesis and relieve hepatic injury in rats.

Prognostic Significance of C-reactive Protein in Urological Cancers: a Systematic Review and Meta-analysis

Dai, Jin,Tang, Kun,Xiao, Wei,Yu, Gan,Zeng, Jin,Li, Wei,Zhang, Ya-Qun,Xu, Hua,Chen, Zhi-Qiang,Ye, Zhang-Qun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.8

Background: C-reactive protein (CRP), considered as a prototypical inflammatory cytokine, has been proposed to be involved in tumor progression through inflammation. Recent studies have indicated CRP as a progostic predictor for urological cancers, but the results remain controversial. Materials and Methods: A systematic search of Medline, Scopus and the Cochrane Library was performed to identify eligible studies published between Jan 1, 2001 and Sep 1, 2013. Outcomes of interest were collected from studies comparing overall survival (OS), cancer-specific survival (CSS) and relapse-free survival (RFS) in patients with elevated CRP levels and those having lower levels. Studies were pooled, and combined hazard ratio (HR) of CRP with its 95% confidence interval (CI) for survival were used for the effect size estimate. Results: A total of 43 studies (7,490 patients) were included in this meta-analysis (25 for RCC, 10 for UC, and 8 for PC). Our pooled results showed that elevated serum CRP level was associated with poor OS (HR: 1.26, 95%CI: 1.22-1.30) and RFS (HR: 1.38 95%CI: 1.29-1.47), respectively. For CSS the pooled HR (HR: 1.33, 95%CI: 1.28-1.39) for higher CRP expression could strongly predict poorer survival in urological cancers. Simultaneously, elevated serum CRP was also significantly associated with poor prognosis in the subgroup analysis. Conclusions: Our pooled results demonstrate that a high serum level of CRP as an inflammation biomarker denotes a poor prognosis of patients with urological cancers. Further large prospective studies should be performed to confirm whether CRP, as a biomarker of inflammation, has a prognostic role in urological cancer progression.

Targeting SHCBP1 Inhibits Cell Proliferation in Human Hepatocellular Carcinoma Cells

Tao, Han-Chuan,Wang, Hai-Xiao,Dai, Min,Gu, Cheng-Yu,Wang, Qun,Han, Ze-Guang,Cai, Bing Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10

Src homology 2 domain containing (SHC) is a proto-oncogene which mediates cell proliferation and carcinogenesis in human carcinomas. Here, the SHC SH2-domain binding protein 1 (SHCBP1) was first established to be up-regulated in human hepatocellular carcinoma (HCC) tissues by array-base comparative genome hybridization (aCGH). Meanwhile, we examine and verify it by quantitative real-time PCR and western blot. Our current data show that SHCBP1 was up-regulated in HCC tissues. Overexpression of SHCBP1 could significantly promote HCC cell proliferation, survival and colony formation in HCC cell lines. Furthermore, knockdown of SHCBP1 induced cell cycle delay and suppressed cell proliferation. Furthermore, SHCBP1 could regulate the expression of activate extracellular signal-regulated kinase 1/2 (ERK1/2) and cyclin D1. Together, our findings indicate that SHCBP1 may contribute to human hepatocellular carcinoma by promoting cell proliferation and may serve as a molecular target of cancer therapy.

A Three-dimensional Biomechanical Model for Numerical Simulation of Dynamic Pressure Functional Performances of Graduated Compression Stocking (GCS)

Liu, Rong,Kwok, Yi-Lin,Li, Yi,Lao, Terence-T,Zhang, Xin,Dai, Xiao-Qun The Korean Fiber Society 2006 Fibers and polymers Vol.7 No.4

The beneficial effects of graduated compression stockings (GCS) in prophylaxis and treatment of venous disorders of human lower extremity have been recognized. However, their pressure functional performances are variable and unstable in practical applications, and the exact mechanisms of action remain controversial. Direct surface pressure measurements and indirect material properties testing are not enough for fully understanding the interaction between stocking and leg. A three dimensional (3D) biomechanical mathematical model for numerically simulating the interaction between leg and GCS in dynamic wear was developed based on the actual geometry of the female leg obtained from 3D reconstruction of MR images and the real size and mechanical properties of the compression stocking prototype. The biomechanical solid leg model consists of bones and soft tissues, and an orthotropic shell model is built for the stocking hose. The dynamic putting-on process is simulated by defining the contact of finite relative sliding between the two objects. The surface pressure magnitude and distribution along the different height levels of the leg and stress profiles of stockings were simulated. As well, their dynamic alterations with time processing were quantitatively analyzed. Through validation, the simulated results showed a reasonable agreement with the experimental measurements, and the simulated pressure gradient distribution from the ankle to the thigh (100:67:30) accorded with the advised criterion by the European committee for standardization. The developed model can be used to predict and visualize the dynamic pressure and stress performances exerted by compression stocking in wear, and to optimize the material mechanical properties in stocking design, thus, helping us understand mechanisms of compression action and improving medical functions of GCS.

Numerical Simulation of Internal Stress Profiles and Three-dimensional Deformations of Lower Extremity Beneath Medical Graduated Compression Stocking (GCS)

Liu, Rong,Kwok, Yi-Lin,Li, Yi,Lao, Terence-T,Dai, Xiao Qun,Zhang, Xin The Korean Fiber Society 2007 Fibers and polymers Vol.8 No.3

The most significant medical function of graduated compression stocking (GCS) is to provide controlled support and pressure to the skin surface and the underlying tissues of the lower extremity, to prevent and treat venous disease, thus improving the blood circulation. However, due to lack of suitable technologies for the experimental measurements, the transfer mechanisms of the external pressure applied by GCS and internal stress states within the leg soft tissue were not well examined, which bring some difficulties to GCS compression design. The present study numerically simulated and analyzed surface pressure applied by GCS and the cross-sectional deformations at the target region of leg. The underlying tissues stress profiles as well as their dynamic alterations with time processing were presented and quantitatively investigated. Moreover, the medical significance of the cross-sectional inner stress distributions was discussed. The validation results indicated that the simulated pressure profiles applied by GCS agreed reasonably well with the measured ones. The developed biomechanical model can be used for prediction and analysis of the pressure functional performances applied by GCSs, thus helping us more understanding mechanisms of compression action and improving their medical functions.