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      • 디지털 워터마킹을 이용한 영상 정보 보호 시스템

        박정빈,정성환,이우선 國立 昌原大學校 精報通信硏究所 1999 精報通信論文集 Vol.3 No.-

        Recently, with advance in computer network and multimedia technology, digital media is rapidly proliferating, and digital copy has been widely practiced. So an efficient technology for the protection of intellectual property is required. Watermark techniques effectively protect the intellectual property for multimedia data, and can prevent an unauthorized person from copying the multimedia data. In this paper, we propose a watermarking scheme to hide watermark information in low-frequency and high-frequency of wavelet transform. Experimental results show that the proposed watermark scheme is robust to several distortions including Gaussian noise and filtering, compression and contrast at different qualities.

      • 에이즈 환자의 거대세포바이러스 감염증

        김홍빈,박상원,김남중,최희정,신동현,오명돈,김우호,정흠,최강원 대한감염학회 1998 감염 Vol.30 No.4

        배 경 : 거대세포바이러스 감염은 인간면역부전바이러스 (Human Immunodeficiency Virus, HIV) 감염자에서 발생하는 가장 중요한 기회감염증의 하나이다. 특히, 국내에서는 95%이상의 국민이 거대세포바이러스의 1차감염을 경험한 상태이므로 에이즈 환자에서 거대세포바이러스 질환의 빈도가 높을 것으로 예상된다. 대상 및 방법 : 1987년 10월부터 1996년 9월까지 서울대학교 병원에서 추적 관찰하였던 128명의 HIV 감염자를 대상으로 하였다. 이들 환자의 의무 기록에서 임상 자료를 얻었다. 거대세포바이러스 망막염은 안과 전문의의 임상적인 소견으로 진단하였으며, 위장관 등 망막이외 부위의 거대세포마이러스 질환은 조직학적으로 확인된 경우에 한하였다. 결 과 : 대상환자 128명의 추적관찰기간은 중앙값이 6(0∼59)개월 이었으며 7명 (5.4%)에서 거대세포바이러스 질환이 발생하였다. 거대세포바이러스 질환은 망막염이 6예, 식도염이 2예, 대장염이 1예, 폐렴 및 부신감염이 1예, 범발성 감염이 1예였다. 거대세포바이러스 질환의 발생빈도는 CD4+ 림프구 수가 적을수록 높았으며, CD4+ 수가 200/㎣미만인 환자 중 15% (6/33)에서 거대세포바이러스 질환이 확인되었다. 11예 중 9예를 ganciclovir로 치료하였으며 이중 7예에서 호전 또는 진행의 억제가 확인되었다. 추적관찰이 가능한 6예 중 3예 (50%)에서 재발하였다. 결 론 : 국내 에이즈 환자에서 거대세포바이러스 질환은 비교적 흔한 기회감염증이다. Background : Cytomegalovirus (CMV) infection is one of the important opportunistic infections in immunocompromised patients. In Korea, seroprevalence of IgG against CMV is over 95%. Therefore, CMV diseases are expected to be a prevalent opportunistic infection in AIDS patients. in Korea. Methods : We reviewed the medical records of 128 patients with HIV infection who visited the Seoul National University Hospital during the period from Nov. 1987 TO Sep. 1996. All the patients were examined by one ophthalmologist and the diagnosis of CMV retinitis were made by funduscopic findings. Other CMV diseases were diagnosed when histopathologic examinations showed the characteristic cytomegalic cells. Results : Median duratior, of follow-up was 8 months. Eleven CMV diseases were found in 7 patients (5.4%): 6 patients ahd retinitis, 2 esophagitis, 1 colitis, 1 pneumonitis, and one patient developed disseminated infection. Fifteen percent (6/33) of the patients whose CD4+ lymphocyte counts were less than 200/㎣ at baseline developed CMV diseases. Out of the 9 cases treated with ganciclovir, 7 improved or were stabilized. No patient received maintenance treatment and 3 had relapsed. Conclusion : CMV diseases are common opportunistic infections in AIDS patients in Korea.

      • KCI등재후보

        탈감작법으로 치료한 인형 재조합 인슐린에 대한 아나필락시스

        박경우(Kyung Woo Park),박현신(Hyun Shin Park),박우상(Sang Woo Park),장철순(Chul Soon Jang),정정환(Chung Whan Chung),홍성빈(Seong Bin Hong),김용성(Yong Seong Kim),박원(Won Park),송정수(Jung Soo Song),최승원(Seung Won Choi) 대한내과학회 2002 대한내과학회지 Vol.62 No.2

        N/A Allergic reaction to insulin is mediated by several mechanisms; differences in amino acid sequence of animal and human insulin, altered tertiary structure of insulin and the presence of non-insulin protein contaminants or pharmaceutical additives. Anaphylactic reactions to insulin only occur in 0.1 to 2% of patients who stopped insulin therapy and have then resumed treatment. We report a diabetic patient who suffered severe anaphylactic reactions to human recombinant insulin, successfully treated by desensitization. A 19-year-old man with type 1 diabetes receiving Insulatard HM? developed generalized urticaria and angioedema with progression to dyspnea, dizziness and syncope. Skin prick test to all kinds of human recombinant insulin products revealed immediate type hypersensitivity and the titer of insulin IgE was increased in serum. The desensitization trial with Velosulin HM? using modified desensitization method was performed. Six months after the desensitization he was taking Velosulin HM? as well as Insulatard HM? without any evidence of systemic allergic reactions.(Korean J Med 62:204-208, 2002)

      • SCIESCOPUSKCI등재

        Impact of Electric Vehicle Penetration-Based Charging Demand on Load Profile

        Park, Woo-Jae,Song, Kyung-Bin,Park, Jung-Wook The Korean Institute of Electrical Engineers 2013 Journal of Electrical Engineering & Technology Vol.8 No.2

        This paper presents a study the change of the load profile on the power system by the charging impact of electric vehicles (EVs) in 2020. The impact of charging EVs on the load demand is determined not only by the number of EVs in usage pattern, but also by the number of EVs being charged at once. The charging load is determined on an hourly basis using the number of the EVs based on different scenarios considering battery size, model, the use of vehicles, charging at home or work, and the method of charging, which is either fast or slow. Focusing on the impact of future load profile in Korea with EVs reaching up 10 and 20 percentage, increased power demand by EVs charging is analyzed. Also, this paper analyzes the impact of a time-of-use (TOU) tariff system on the charging of EVs in Korea. The results demonstrate how the penetration of EVs increases the load profile and decreases charging demand by TOU tariff system on the future power system.

      • KCI등재

        Analysis of protein expression in Brucella abortus mutants with different growth rates by two-dimensional gel electrophoresis and LC-MS/MS peptide analysis

        Woo Bin Park,Young Bin Im,Soojin Shim,유한상 대한수의학회 2018 Journal of Veterinary Science Vol.19 No.2

        Brucella abortus is a bacterium that causes brucellosis and is the causative agent of worldwide zoonoses. Pathogenesis of the B. abortusinfection is complicated, and several researchers have attempted to elucidate the infection mechanism of B. abortus. While several proteinshave been revealed as pathogenic factors by previous researchers, the underlying mechanism of B. abortus infection is unresolved. In thisstudy, we identified proteins showing different expression levels in B. abortus mutants with different biological characteristics that weregenerated by random insertion of a transposon. Five mutants were selected based on biological characteristics, in particular, their growthfeatures. Total proteins of mutant and wild-type B. abortus were purified and subjected to two-dimensional gel electrophoresis. Thirty proteinspots of each mutant with expression increases or decreases were selected; those with a change of more than 2-fold were compared with thewild-type. Selected spots underwent liquid chromatography tandem mass spectrometry for peptide analysis. DnaK and ClpB, involved inprotein aggregation, increased. SecA and GAPDH, associated with energy metabolism, decreased in some mutants with a growth rate slowerthan that of the wild-type. Mutants with slower growth showed a decrease in energy metabolism-related proteins, while mutants with fastergrowth showed an increase in pathogenicity-related proteins.

      • Parameter Optimization of SFCL With Wind-Turbine Generation System Based on Its Protective Coordination

        Woo-Jae Park,Byung Chul Sung,Kyung-Bin Song,Jung-Wook Park IEEE 2011 IEEE transactions on applied superconductivity Vol.21 No.3

        <P>This paper describes a study to determine the optimal resistance of a superconducting fault current limiter (SFCL) connected to a wind-turbine generation system (WTGS) in series considering its protective coordination. The connection of the WTGS to the electric power grid may have serious effects on the stability and reliability of the overall system during a contingency due to the increase in fault currents. Moreover, it causes malfunction in the protective devices such as overcurrent relays (OCRs). To deal with this problem, the SFCL is applied to reduce the level of fault current increased by the connection of the WTGS. Then, to determine the optimal parameter of the SFCL, protective coordination between the existing multiple OCRs is considered based on the computation of fault current by the equivalent voltage source method. The effectiveness of the optimal resistance for the SFCL is evaluated by the time-domain simulation with the power systems computer aided design/electromagnetic transients including DC (PSCAD/EMTDC) software. The results show that protective coordination is well maintained without changing the previous settings of existing OCRs by applying the SFCL with its optimal parameter. Therefore, the system can keep its suitable reliability even when the level of fault current is increased by connecting the WTGS to the power system.</P>

      • Long-Term Clinical Outcomes of True and Non-True Bifurcation Lesions According to Medina Classification- Results From the COBIS (COronary BIfurcation Stent) II Registry.

        Park, Taek Kyu,Park, Yong Hwan,Song, Young Bin,Oh, Ju Hyeon,Chun, Woo Jung,Kang, Gu Hyun,Jang, Woo Jin,Hahn, Joo-Yong,Yang, Jeong Hoon,Choi, Seung-Hyuk,Choi, Jin-Ho,Lee, Sang Hoon,Jeong, Myung-Ho,Kim, Japanese Circulation Society 2015 Circulation journal Vol.79 No.9

        <P>Little is known about the clinical outcomes of patients with different types of coronary bifurcation lesions. We sought to compare long-term clinical outcomes of patients with true or non-true bifurcation lesions who underwent percutaneous coronary intervention.Methods?and?Results:We compared major adverse cardiac events (MACE: cardiac death, myocardial infarction [MI], or target lesion revascularization) between 1,502 patients with true bifurcation lesions (51.8%) and 1,395 with non-true bifurcation lesions (48.2%). True bifurcation lesions were defined as Medina classification (1.1.1), (1.0.1), or (0.1.1) lesions. During a median follow-up of 36 months, MACE occurred in 296 (10.2%) patients. Patients with true bifurcation lesions had a significantly higher risk of MACE than those with non-true bifurcation lesions (HR 1.39; 95% CI 1.08-1.80; P=0.01). Among true bifurcation lesions, Medina (1.1.1) and (0.1.1) were associated with a higher risk of cardiac death or MI than Medina (1.0.1) (HR 4.15; 95% CI 1.01-17.1; P=0.05). During the procedure, side branch occlusion occurred more frequently in Medina (1.1.1) and (1.0.1) than Medina (0.1.1) lesions (11.5% vs. 7.4%, P=0.03).</P>

      • KCI등재

        Impact of Electric Vehicle Penetration-Based Charging Demand on Load Profile

        Woo-Jae Park,Kyung-Bin Song,Jung-Wook Park 대한전기학회 2013 Journal of Electrical Engineering & Technology Vol.8 No.2

        This paper presents a study the change of the load profile on the power system by the charging impact of electric vehicles (EVs) in 2020. The impact of charging EVs on the load demand is determined not only by the number of EVs in usage pattern, but also by the number of EVs being charged at once. The charging load is determined on an hourly basis using the number of the EVs based on different scenarios considering battery size, model, the use of vehicles, charging at home or work, and the method of charging, which is either fast or slow. Focusing on the impact of future load profile in Korea with EVs reaching up 10 and 20 percentage, increased power demand by EVs charging is analyzed. Also, this paper analyzes the impact of a time-of-use (TOU) tariff system on the charging of EVs in Korea. The results demonstrate how the penetration of EVs increases the load profile and decreases charging demand by TOU tariff system on the future power system.

      • KCI등재후보

        Germination Characteristics and Seed Dormancy of Iris dichotoma Pall., an Endangered Species Native to Korea

        Park, Hyeong Bin,Lee, Byoung-Doo,Lee, Chang Woo,Hwang, Jung Eun,Park, Hwan Joon,Kim, Seongjun,An, Jiae,Kim, Pyoung Beom,Kim, Nam Young National Institute of Ecology 2021 국립생태원회보(PNIE) Vol.2 No.4

        Iris dichotoma Pall. found on Daechung Island in Korea has been designated as an endangered species. To aid in conservation efforts of this species, this study investigated its germination characteristics and seed dormancy type. Four sets of seeds were incubated at different temperatures (4/1℃, 15/6℃, 20/10℃, and 25/15℃). One set of seeds was cold stratified (4 weeks at 4/1℃). The final germination rate and mean germination time showed that the optimal germination temperature was 25/15℃. Final germination rates were ~70%, showing no significant difference among temperature treatments. However, mean germination time were significantly different among all temperature treatments except for 4/1℃. Mean germination time for seeds with temperature treatments of 15/6℃, 20/10℃, and 25/15℃ were 3.2, 2.1, and 1.5 weeks, respectively. At 25/15℃, the mean germination time was half of that at 15/6℃. Seeds of I. dichotoma had fully developed embryos at the time of dispersal. No additional growth of the embryo was observed. Cold stratification did not affect the final germination rate or the mean germination time. This study shows that seeds of I. dichotoma have no physiological or morphological dormancy, unlike other members of the Iris genus known to have seed dormancy that needs a relatively high incubation temperature (≥25/15℃) for mass propagation to occur. These results will be useful for understanding ecophysiological mechanisms related to the species' habitat. They are also useful for mass propagation of I. dichotoma for the purpose of conserving this endangered species.

      • KCI등재

        Comparison of cytokine genes related with immune responses in canine macrophages using different culture models after infection with Brucella canis

        Woo Bin Park,Suji Kim,Soojin Shim,Han Sang Yoo 한국예방수의학회 2019 예방수의학회지 Vol.43 No.4

        Although canine brucellosis has been known to be an important re-emerging zoonosis, the pathophysiological mechanisms of Brucella canis infection remains clues to be solved. Different culture models, single and co-culture models, were constructed with canine epithelial cells, D17 and macrophage, DH82 to investigate the induction of immune responses in in vivo B. canis infection. Expression of genes related with induction of immune responses, Th1, Th2 and Th17, was compared in the two different models after the bacterial infection. In this study, expression of cytokine genes, IL-1β, IL-5, IL-6, IL-10, IL-23, and TNF-α was quantified in the DH82 at different time points using RT-qPCR in the two different culture systems after the infection. Cytokine genes related with Th1, IL-1β and TNF-α and Th17, IL-6 and IL-23 were expressed with time-dependent manners in the both systems (p<0.05). However, increase of Th2-related cytokine genes expression was not detectable in the both systems by comparison with control. The expression of Th1 and Th17 related cytokine genes was earlier in single cell culture than those in co-culture model (p<0.05). In general, amounts of the expressed genes were shown higher in single cell model than those in co-culture models. This study indicate that Th1 and Th17-associated immune responses are central to B. canis infection in dogs. In addition, it suggests a specific role of epithelial cells in the B. canis infection in vivo, which should resolved in the further study.

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