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안면부, 유방 및 상완부에 발생한 홍반성 루푸스 지방층염 1예
송유근,손두식,명형준,이현정,임중규,김순호,김윤아 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2
Lupus erythematous panniculitis is a chronic inflammatory disease of subcutaneous fat that occurs in 2-3% of patients with systemic lupus erythematosus. Lupus erythematous panniculitis typically presents with firm, indurated subcutaneous nodules or plaques commonly developed in proximal extremities, trunks, head and neck. Face, breast and upper extremities involvement with lupus erythematous panniculitis has been infrequently reported. We report a case of lupus erythematous panniculitis developed in a 27-year-old female confirmed by histologic features and laboratory findings.
麥酒麥의 (1-3,1-4)-β-glucanase 遺傳子의 構造와 發現 樣狀
유남희,윤성중,최경구,김제환,박충웅 全北大學校 基礎科學硏究所 1994 基礎科學 Vol.16 No.-
禾穀類 種子 發芽時 호분층과 ??組織의 細胞壁에 多量 含有되어 있는 (1-3, 1-4)-β-glucan을 分解하여 種子의 發芽에 必要한 加水分解酵素의 分泌 및 擴散 浸透를 돕는다. 本 硏究에서는 國內 麥酒麥의 (1-3, 1-4)-β-glucanase 遺傳子의 構造 및 發現 에 대한 基礎 情報를 얻기 위하여 生化學的 및 分子生物學的 方法을 利用하여 發芽種子 및 어린 잎에서의 酵素活性과 遺傳子의 發芽樣狀 그리고 遺傳子의 構造 等을 調査하였다. 麥酒麥 發芽種子中 (1-3, 1-4)-β-glucanase 活性은 發芽 7日째에 제일 높았다. (1-3, 1-4)-β-glucanase의 活性測定에 使用한 (1-3, 1-4)-β-glucan이 (1-4)-β-glucanase에 의해 分解될 可能性이 있으므로 (1-4)-β-glucanase의 活性도 測定하였는데 (1-4)-β-glucanase의 活性이 매우 낮게 나타나서(1-4)-β-glucanase가 (1-3, 1-4)-β-glucanase을 分解하여 (1-3, 1-4)-β-glucanse의 活性에 影響을 미쳤을 可能性이 매우 낮았다. 麥酒麥의 (1-3, 1-4)-β-glucanase 遺傳子 構造를 PCR을 利用하여 調査하였던바 國內 麥酒麥의 (1-3, 1-4)-β-glucanase 遺傳子 構造는 外國의 다른 品種들이나 귀리의 遺傳子 構造와 대단히 類似하였다. 酵素活性 測定과 귀리의 (1-3, 1-4)-β-glucanase cDNA clone을 ?識子로 利用한 보리의 mRNA 分析에 의해서 發芽傳子 및 어린 잎에서 (1-3, 1-4)-β-glucanase가 種子發芽 以外에도 生育中인 組織細胞의 伸張과 發育 및 β-glucan 再利用에 泌要한 β-glucan 代謝에 關與하고 있음을 示唆하는 結果라 생각된다. (1-3, 1-4)-β-glucans hydrolysis of cell wall (1-3, 1-4)-β-glucanas accompanies degradation of endosperm cell walls during cereal seed germination. To investigate (1-3, 1-4)-β-glucanase expression pattern in Korean malting barley, (1-3, 1-4)-β-glucanase activity, gene structure and mRNA expression patterns werre examined. (1-3, 1-4)-β-glucanase activity increased as germination proceeded and the highest enzyme activity was detected in seeds germinated for 7 days. Because (1-4)-β-glucanase have a potential to degrade (1-3, 1-4)-β-glucans, (1-4)-β-glucanase activity was also determined. (1-4)-β-glucanase activity, however, was very low minimizing possibility of (1-4)-β-glucanase action on (1-3, 1-4)-β-glucan substrate. PCR technique was employed to investigate (1-3, 1-4)-β-glucanase gene structure. The amplification product of the expected size from the targeted sites of Dusan #29 indicated that (1-3, 1-4)-β-glucanase systems were conserved in different barley varieties and even in oats. (1-3, 1-4)-β-glucanase activity and mRNAs were detected in young leaves as well as in germinating seeds. This may suggest that (1-3, 1-4)-β-glucanase are also involved in β-glucan metabolism required for cell elongation and β-glucan reutilization during leaf growth and developmetn.
김희남,송승기,정윤중,윤여권,김희원,조상원,심재환 한국안전학회 2003 한국안전학회지 Vol.18 No.2
The magnetic polishing is the useful method to finish some machinery fabrications by using magnetic power. This method is one of the precision techniques and has an aim for clean technology in the transportation of the pure gas in the clean pipes. The magnetic abrasive polishing method is not so common in the field of machine that it is not known to widely. There are rarely researcher in this field because of non-effectiveness of magnetic abrasive. Therefore, in this paper we deals with the development of the magnetic abrasive with the use of Ba-Ferrite. In this development, abrasive grain WA has been made by using the resin bond fabricated at low temperature. And magnetic abrasive powder was fabricated from the Ba-Ferrite which was crushed into 200 mesh. The XRD analysis result shows that only WA abrasive and Ba-Ferrite crystal peaks were detected, explaining that resin bond was not any more to contribute chemical reaction. From SEM analysis, we found that WA abrasive and Ba-Ferrite were strongly bonding with each other.
장충근,유중렬,송재용,윤만영,박재형,손대락 경북대학교 센서기술연구소 1991 센서技術學術大會論文集 Vol.2 No.1
자기저항센서를 제작하기 위하여 Mo-permalloy(Ni:79.43%, Fe:14.47%, Mo:5.7%, Mn:0.38%, C:0.013%)를 슬라이드 그라스에 진공증착하여 sensor element를 제작한 후 포화자속밀도(B_(s)), 보자력(H_(c)), 자기이방성상수(K//), 자기저항변화율(ΔR/R)을 조사하였다. 진공증착된 permalloy 박막의 포화자속밀도는 0.746T 이었으며, 자화주파수 1kHz에서 보자력은 2.90A/cm(//),1.98A/cm(⊥) 이었고, 열처리 후에 1.79A/cm(//). 1.37A/cm(⊥)로 감소되었다. 한편 이 소자의 자기이방성상수는 1.38X10^(4)erg/cm^(3) 이었으며 5x1^(0-3)T의 자장변화에 대만 저항변화율(ΔR/R)은 2.0% 이었다. 앞으로 이 소자의 온도특성, 잡음특성 및 내열성 등을 조사하고자 한다. To fabricate magnetoresistive sensor, Mo-permalloy(Ni:79.43%, Fe:14.47%, Mo:5.7%, Mn:0.38%, C:0.013%) was evaporated on the slide glass. Saturation magnetic induction(B_(s)), coercive field strength(H_(a)), magnetic anisotropy constant(K), and magnetoresistance were measured for the fabricated samples. The evaporated samples show that saturation magnetic induction was 0.746T, and coercive field strengthes were 2,90A/cm(//) and 1.98A/cm(⊥), and this values were reduced to 1.79A/cm(//) and 1.37A/cm(⊥) respectively after annealing. For the measurement of coercive field strength, magnetizing frequency of 1kHz was used. For the fabricated sensor element, magnetic anisotropic constant was 1.38X10^(4)erg/cm^(3) and magneto-resistance change(ΔR/R) was 2.0% under the magnetic field change of 5X10^(-3)T, We will continue study on the characteristics for the temperature, heat resistance, and noise.
측두하악장애 환자 중 하악과두의 퇴행성 골 변화를 보이는 환자의 분포 및 임상적 특징
임용규,김민지,김연중,송윤헌,이동렬 대한치과교정학회 2006 대한치과교정학회지 Vol.36 No.6
측두하악장애 환자 중 하악과두의 퇴행성 골 변화를 보이는 환자의 분포와 임상적 특징을 규명하고자 측두하악장애로 진단받은 6,070명의 환자들을 대상으로 연구를 시행하였다. 환자들의 초진 시 파노라마와 TMJ 파노라마 사진을 관찰하여 하악과두의 퇴행성 골 변화 유무를 기준으로 환자들을 퇴행성 골 변화를 보이는 군(DJD군)과 골 변화를 보이지 않는 군(non-DJD군)으로 나누고, 환자들의 초진 의무기록을 바탕으로 두 군 간의 특징을 비교, 분석하였으며, 각종 변수들이 DJD 발병에 미치는 상대적 위험성을 측정하기 위하여 로지스틱 회귀분석을 시행하였다. 연구 결과 전체 환자 중 DJD군에 속한 환자는 31.7%였고, non-DJD군에 속하는 환자는 68.3%였다. DJD군은 성별에 따라 다른 분포를 보여 남자보다 여자의 이환율이 높았고, 10대와 20대에서 가장 높은 분포를 보였다. 환자의 내원 주소 중에서는 전치부 개방교합, 턱의 후퇴감, 안모 비대칭, 개구장애를 주소로 내원한 환자가 다른 주소로 내원한 환자들에 비해 DJD를 보일 위험성이 높았으며, 교정치료 경력이나 중심위-중심교합위 변위 그리고 염발음을 보이는 환자도 DJD군에 속할 위험성이 큰 것으로 나타났다. 따라서 측두하악장애를 가진 환자 중 30세 이하의 여성이 위와 같은 임상적 특징을 보이는 경우, 교정치료를 계획할 때 DJD에 이환 되었을 가능성에 대하여 충분히 주의를 기울여야 할 것으로 생각된다. (대치교정지 2006;36(6):402-11) Objective: This study was carried out to evaluate the distribution and clinical features of patients with degenerative change of the mandibular condyle. Methods: Six thousand and seventy patients with TMD (temporomandibular disorder) were selected for this study, who had complete initial clinical records and radiographs. Panorama and TMJ panorama radiographs were used to screen the degenerative change in the condyle, and the patients were divided into DJD (degenerative joint disease) and non-DJD groups. Results: The distribution and clinical features of the two groups were compared. Out of the total number of patients, 31.7% were in the DJD group, and 68.3% were in the non-DJD group. The portion of females was larger in the DJD group (80.8%) than in the non-DJD group (67.5%), and the DJD group had high prevalence in the second and third decades. Lack of incisal contact, retrusive chin, facial asymmetry, and mouth opening limitation were the chief complaints of the patients who had positive relation to DJD. Conclusion: Patients with an orthodontic treatment history, CO-CR discrepancy and crepitation were at possible risk of having DJD. (Korean J Orthod 2006;36(6):402-11)
분자표지 이용 Polyphenol Oxidase 저활성 국산밀 유전자원 선발
Song Joong Yun,Kyeong-Hoon Kim,Chon-Sik Kang,Young-Keun Cheong,Chul Soo Park,Kyung-Ho Kim,Hak-Shin Kim,Young-Jin Kim 한국육종학회 2012 한국육종학회지 Vol.44 No.1
The color of wheat flour and dough affect significantly on the quality of wheat. The major factor causing darkening of dough color is activity of polyphenol oxidase (PPO). Therefore, we examined the relationship between the PPO activities and the genotypes of the PPO-specific molecular markers in Korean wheat cultivars, and tested the usefulness of the selected markers for the selection of Korean wheat germplasm lines low in PPO activity. Five sequence-tagged site (STS) markers specific to wheat PPO genes, PPO-05, PPO-16, PPO-18, PPO-30 and PPO-43, were examined for their levels of polymorphism in Korean wheat cultivars. The genotypes of the marker PPO-18, which is linked to Ppo-A1 locus, were correlated significantly highly with the levels of grain PPO activity. Furthermore, Korean wheat cultivars could be classified into the high or low PPO activity group by the allele type of Ppo-A1 which was differentiated by the PPO-18. Grain PPO activity was lower about twice in the cultivars with Ppo-A1b allele than in those with Ppo-A1a allele. The cultivars with Ppo-A1b allele had lower grain weight and wide grain width, also they had less ash, protein, Fe and total polyphenol than those with Ppo-A1a allele. Thus, the lightness of flour and dough sheet was brighter in the cultivars with Ppo-A1b allele. The four wheat cultivars including Suwon252, which had lowest PPO activity and Ppo-A1b allele, were selected from 200 genetic lines as valuable genetic resources for the breeding of wheat variety with bright white-colored flour.