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- 저자 : ( Seung Hee Jo ) (검색결과 735 건)
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이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1
연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.
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육조영,윤찬호,김범수,노덕선,이무연,배진희,이승훈 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6
Information has become a strategic tool with progress of sports science and sports technology. Demand on sports information is spreading to leisure, recreation, sociology, science of nutrition, psychology, sports medicine, sports therapy, prophylactic medicine, alternative medicine, sports industry and sports nature etc. if on line data base can be manipulated freely then acceleration and quality improvement of the study in this field can be effected and it is possible to gain new insight for receiving latest information But next problem is cost for use. For this reason this author summarized quick and effective on lline search points as follows: 1. Data base should be chosen with clear purpose for its use. Conduct prior investigation on contents and fee system of data base. With the same data base fee system may be differed depending on distributor therefore it is necessary to try different distributors at first as much as possible. 2. Prior to starting on line search prepare search method. If on line is started and then search method is checked than quickly telephone charge will go up. Search method should be prepared in advance by thinking sufficiently of what theme is to be searched. 3. Look for good advisor: lf there is no advisor nearby then the best thing is counselling with the person in charge for the distributor. If the result of search is stored at floppy disk by "downloading" then even after communication line is cut off it will be possible to print out anytime. 4. In this study the author explained about on-line search of lterature data line but recently it is possible to search overseas sports news or information on rate of victory or defeat of prfessional footbali etc. in real time. In Japan it is possible to search feature articles of Nihon Kesai or Asahi (except culture and sports column) by on-line. However in our country there are not many data bases in the field of sports and physical education which can be on-line searched. Our country belongs to up per level in the world in terms of study of sports science and technology and we are attracting attention from countries in Asia and from different parts of the world and the task facing us now is developing independent and unique data base for our country.
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최주희,강영조,조승래 東亞大學校 建設技術硏究所 2005 硏究論文集 Vol.29 No.1
The purpose of this study is to examine and analyze behaviors of using peripheral areas of urban river, seeking towards an effective arrangement of such areas. For the purpose, this researcher surveyed the terrace land on the Oncheoncheon, expecially the section between Sebyeong and Yeonsan Brigdes, whose ratio of using by people was increased after arranged. Then the researcher investigated users of the terrace land by using tables under Observation Research Method and Behavior Mapping in accordance with their gender, age and behavioral type. Results of the study can be summarized as follows. First, there were differences in the behavior of using the terrace land among users in accordance with the type of facility located within th space. Second, there were differences among users in the ratio of using th terrace land at each time in weekdays and weekend, irrespective of those users' gender. Third, an area where there are sport facilities were being used more frequently than any other areas. Finally, the researcher hopes that results of the study will provide basic information for any other arrangement of area around river.
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육조영,임정일,윤찬호,이무연,노덕선,배진희,이승훈 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6
As Follow suggested : The purpose of this study was to consider tendency of modern sports information. today Modernst information system had four areas such as collection, clearance, communication and application So, most literuture of America and Europe was collected, cleared, communicated and apilcated in international sports data base. If we utillited communication circuit properly, we could use sports information beneficently at the laboratory and office. In the future and now, one was that special sports institution needed to obtain Education about sports imformation such as information of specialization, and information of knowledge on both soft phase and hard phase of new media. Although korea used date base of foriegn country efficiently, korea had to make effort to create its own information system and wish to avoid friction of economy and fiction of information.
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아미노산 투여가 운동중 싸이클선수의 젖산 및 심박수에 미치는 영향
이승국,유병렬,김문희,김완조,이선장 韓國體育大學校附屬 體育科學硏究所 1992 韓國體育大學校附屬 體育科學硏究所論文集 Vol.11 No.1
The purpose of the study was to determine whether a 15.6mg.Kg ??' does of glutamate given one hour prior to incremental exercise test would reduce the lactate formation. Five well trained cyclists served as subjects in this experiment which included a placebo and glutamate trial. The subjects initially work on treadmill 200m/min for 3 minutes and here increased the workload by 20m/min every 3minutes until exhaustion. Blood lactate were collected from finger-tip. Subjects in the glutamate trial showed significantly lower lactate formation during exercise then they did in the placebo trial. In both groups no significant difference was found on heart rate. During the recovery lactate and heart, rate were unaltered in either the glutamate or placebo trials. In summary, glutamate ingestion may reduce lactate formation resultly improvement of performance.
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서울에서 分離된 腸內細菌의 抗生劑耐性과 耐性傳達因子에 관한 硏究
劉承兆,金勝喜,염곤 成均館大學校 1980 論文集 Vol.28 No.-
Studies on drug resistance and R-factor of enteric bacterial flora isolated from Seoul area(June 1978∼Sept. 1978). Drug Resistance and the distribution of R-factor were examined using Escherichia coli, Salmonella, Shigella, Enterobacter and Klebsiella isolated from patients in Seoul area from June 1978 through Sept. 1978. 1. Of Escherichia coli, 147 strains (87.50%) were resistant to Ampicillin, but 2 stranins (1.19%) only were resistant to Nalidixic acid. Of Shigella, no strains were resistant to Gentamicin, and the persectage of resistancd to Streptomycin was highest (26.53%). Of Salmonella, no strains were resistant to Nalidixic acid, Tetracyclin, Gentamicin, Chloramphenicol, but the percentage of resistance to Streptomycin was high (95.04%). Of Enterobacter, 100% were tesistant to Amplicillin and Tetracyclin and of Klebsiella, 100% were resistant to Ampicillin. 2. Of Escherichia coli, most of strains were multiply resistant, while only 2 strains were singly resistant. Of Salmonella, 88.14% of resistant strains were singly resistant and of Enterobacter, all of 29 resistant strains were multiply resistant. 3. Escherichia coli, transferred R-factor in 81.76%, Shigella 25.00%, Klebsiella 93.48%, Enterobacter 86.96%, while Salmonella didn't transfer R-factor at all. 4. 23 resistant patterns of R-factor were found ifn Escherichia coli, 4 resistant patterns in Shigella, 7 resistant patterns in Klebsiella, and 3 resistant patterns in Enterobacter, especially, a resistant pattern of R-factor (AP)^r was 54.62% in Escherichia coli, 57.1% in Shigella, and 35.00% in Enterobacter, which was the highest one of resistent patterns of R-factor, while (AP, TC)^r was 48.84% in Klebsiella. 5. According to the result of examination, the multiply resistant strains transferred R- factor more easily than the singly resistant strains.
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