서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1994)

김재홍,안진균,정성재,김영태,김중환,김시영,이석종,이홍렬,서호석,김경훈,권혁진,정우권,고우석,이용석,안필수,오준규,오용섭 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.1

Background : In recent years gonorrhoea has been panendemic and remains one of the most common Sexually Transmitted Diseases in the world, especially in developing countries. Objective & Method : For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria Gonorrhoeae(PPNG), Ive have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1994, 168 strains of N. gonorrhoeae were isolated, among which 109 (64,9% ) were PPNG. Conclustion : Our results suggests that the prevalence of PPNG in Seoul is still increasing.

장기표면의 내외봉한관과 봉한소체의 형태학적 관찰

안성훈 ( Seong Hun Ahn ),김민수 ( Min Su Kim ),이상훈 ( Sang Hun Lee ),권오상 ( O Sang Kwon ),김재효 ( Jae Hyo Kim ),소광섭 ( Kwang Sup Soh ),손인철 ( In Chul Sohn ) 대한경락경혈학회 2009 Korean Journal of Acupuncture Vol.26 No.1

Objective: In 1960`s Bonghan Kim`s team found BongHan(BH) ducts which were presumed as acupuncture meridians and BH corpuscles. They asserted Bonghan theory and SanAl theory which was involved in cell division and cell restoration. However, many other experiments which had been operated to demonstrate and find the existence of BH ducts had failed because of the secret of blue stain drugs. During the last several years, BongHan theory has been revived through experimental researches to find the anatomical structures of BH ducts and corpuscles by Soh`s Biomedical Physics Lab. Soh`s research team used the staining with Janus Green B, Alcian blue, nanoparticles and Acridine Orange. We used DAPI staining to find the existence of BH ducts and the corpuscles and to observe nuclear arrangement. Methods: We used japan white rabbits as experimental animals. BH ducts and corpuscles were stained with DAPI. The nucleus configuration in BH ducts stained with DAPI were observed with microscope. Results: In this study, we found thread like structures in silver white color distinguished from the blood vessels, nerves and lymph vessels. These thread like vessels in the linear duct shape were connected to same colored mass in the ball shape. Thread like structures we found could be separated easily from the surrounding other organ mass. The nuclei of the thread like structure in DAPI staining, are about 10~20㎛ length, in rod shape and linear arrangement. Conclusion: We concluded that the thread like structure we found was same vessel reported by Soh`s research team, BongHan ducts and corpuscle.

소아 두뇌외상의 임상적 고찰

서성일,송시헌,김성호,김관태,김윤 대한신경외과학회 1995 Journal of Korean neurosurgical society Vol.24 No.2

The clinical analysis was carried out with 182 cases of craniocerebral injuries under 15 years of age, admitted at the Department of Neurosurgery, Chung Nam National Universty Hospital during the period from September, 1990 to September 1993. Following results were obtained : 1) There were 133 males and 49 females and sex ratio was 2.7% 2) Age incidence of the accidents was greatest at 6 years of age and mostly distributed to the age group between 4 to 7. 3) Seasonal peak of the accidents was at May. 4) The accident occurred mostly botween 4 P.m. and 6 P.m in a day.5) The most frequent cause of the craniocerebral injuries was traffic accident(105cases, 57.69%) 6) No deterioration of cansciousness before and after the admission was doserved in 68cases(37.36%) 7) Pupillary change was observed in 25 cases and Babinski sign was elicitable in 31cases 8) Early convulsion and vomiting were frequent symptoms in childhood. 9) Skull fracture was observed in 72 cases(39.56%) in which linear fracture was most frequent and predilection site was parietal bone. 10) The accompanying rate of skull fracture in intracranial hemorrhage was 65.54% 11) Associated injures were found in 44 cases(24.18%). The frequent ones were e xtremity fracture, clavicle fracture 12) The overall mortality was 7.14%.

원발성 유방암에서 Sodium Iodide Symporter의 발현과 ^(99m)Tc-MIBI 유방스캔의 관계

석주원,김성장,곽희숙,이창훈,김인주,김용기,배영태,김동수 대한핵의학회 2002 핵의학 분자영상 Vol.36 No.6

목적: hNIS는 갑상선 조직 외에 다른 조직들에서도 발현된다고 알려져 있다. 유방암 세포는 그런 조직들 중에 하나이며, 그에 의한 유방암의 방사성옥소치료의 가능성이 제시되고 있다. 본 연구에서는 유방암 조직에서 hNIS의 발현정도를 알아보고, ^99mTc-MIBI 유방스캔과 hNIS의 발현 정도와의 관계를 조사하여 보았다. 대상 및 방법: 본 연구에서는 유방암으로 수술을 시행했던 56명의 환자를 대상으로 하였다. hNIS의 발현은 면역조직화학염색에 의해서 평가되었으며, 그 결과를 ^99mTc-MIBI 유방스캔의 판정 결과와 비교하였다. 결과: 전체 56명의 환자에서 hNIS의 발현율은 41.1%였다. 병리학적 진단에 의해 침윤성관상피암종이었던 49명에서의 발현율은 42.9%, 관상피내암종이었던 7명에서의 발현율은 28.6%였다. ^99mTc-MIBI 유방스캔에서 국소섭취 소견이 관찰되었던 41명에서의 hNIS의 발현율은 31.7%였다. 비정상적인 섭취 소견이 관찰되지 않았던 15명의 환자에서의 hNIS의 발현율이 의미있게 높게 관찰되었다(66.7%, p>0.05). 결론: 유방암 환자에서의 hNIS의 발현율은 그다지 높지 않았다. ^99mTc-MIBI 유방스캔에서 섭취증가 소견이 없을 때 hNIS의 발현율이 더 높았다. Purpose: Human Na^+/I- symporter (hNIS) is known to be expressed in many tissues other than thyroid gland. The breast cancer cells are one of them and the possibility of radioiodine therapy in treatment of the breast cancer may be suggested. We investigated the expression rate of hNIS and the relationship between the expression of hNIS and the finding of 99mTc-MIBI scintimammography in the breast cancer. Materials and Methods: Surgically proved 56 patients with breast cancer were the subjects of this study. The expression of hNIS were evaluated by immunohistochemistry and the results were compared to the findings of 99mTc-MIBI scintimammography. Results: Overall expression rate of hNIS was 41.1% in 56 patients. According to the pathologic diagnosis, it was 42.9% in 49 patients with invasive ductal carcinoma and 28.6% in the 7 patients with ductal carcinoma in situ. The expression rate of hNIS in the 41 cases with a focal increased uptake at he breast lesion on 99mTc-MIBI scintimammogram was 31.7%. That in the 15 cases without any abnormal uptake on the scan was significantly higher(66.7%, p<0.05). Conclusion: The expression rate of hNIS in the patients with breast cancer was not so high. The rate was higher in the patients with no increased uptake at the breast lesion on 99mTc-MIBI scintimammography. (Korean J Nucl Med 2002;36;325-32)

有機色素分子와 陰이온 界面活性劑 사이의 相互作用에 關한 吸收分光學的 硏究

송기동,김일두,박성규,김준태,김성현 조선대학교 기초과학연구소 1990 自然科學硏究 Vol.13 No.1

The metachromatic behavior of methylene blue (MB) ia aqueous solution and in the presense of sodium dodecyl sulfate (SDS) have been studied by the absorption spectroscopic method. The results are as follows. The association force of the MB molecules in aqueous solution seems to be complex of three factors, i.e., London's dispersion force, the hydrophobic interaction and the interaction between permanent dipoles it has been measured of critical micelle concentration (CMC) in aqueous solution of SDS and that of MB-SDS to be 8.0mM and 7.9mM respectively. This indifference between CMC values of the pure SDS and MB-SDS system would mean the formation of dye-rich induced micelles(drim). The spectral changes of MB-SDS system with the addition of the inorganic salts have been observed. The addition of the salt into the solution causes the redistribution of MB molecules in the complex(D_n^+ S_m^-). It would be resulted from the decrease of the stacking effect between the bound MB molecules. The spectral changes observed in the MB-SDS system with the increase of the S/D values are analyzed and the behavior of the meta band is explainsd in terms of the stacking theory and micelle formation theory

갈치속젓의 휘발성성분에 관한 연구

김훈,장성민,윤성숙,박승영,김소정,차용준 Institute of Genetic Engineering Changwon National 1999 Gene and Protein Vol.3 No.1

Volatile components in salt-fermented hair tail viscera were anlayzed by simultaneous steam distillation-solvent extraction method and gas chromatography/mass spectrometry method. Seventy four compounds were detected and composed mainly of aldehydes(15 compounds), ketones(7), alcohols(13), nitrogen containing compounds(5), esters(6), sulfur containing compounds(4), aromatic compounds(10) and miscellaneous compounds(14). Among these, some compound groups which were known to have generally the low flavor thresholds, such as aldehydes, ketones, nitrogen containing compounds, esters having low molecular weight and sulfur containing compounds, were supposed to be having major effects on the overall flavor of salt-fermented hair tail viscera.

중추신경계 화농성 감염의 수술적치험

김성호,송시헌,김관태,김윤 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

Authors experienced 36 surgical cases of pyogenic central nervous system infections including brain abscess, subdural empyema, skull osteomylitis with epidural abscess, intraspinal abscess and other rare infections. The incidence was hightest in the 5th and 6th decade, and male patients were predominant. About 56% of the CNS infections were occured after opdraions. The most common causative organisms were staphylococcus aureus. WBC count, ESR and body temperature were not diagnostic in CNS infections. No patient died among the brain abscess cases and the overall mortality rate of CNS infections was 8%.

2021년도 1학기 신라대학교 재학생의 부산인식 설문조사 분석 : 관광경영학부생을 대상으로

김대래 · 양승훈 · 장희정 신라대학교 부산학연구센터 2021 부산연구 Vol.19 No.1

이 연구는 매학기 신라대학교 재학생을 대상으로 이루어지는 설문조사 분석의 일환으로 작성되었 다. 2021년도 1학기에는 국제관광경영학부 학생들을 대상으로 설문조사를 하였다. 응답자는 원래 108명이었으나 그 가운데 부산에서 출생한 56명을 대상으로 분석하였다. 학생들의 종교와 아버지와 어머니의 고향 그리고 부산의 대표적인 음식과 장소에 대한 학생들의 인식을 조사하였다. 또 부산사 람들의 좋은 성격과 나쁜 성격이 무엇인가에 대해서 조사하였다. 아울러 부산에 어떤 것이 새로 생 기면 좋은지에 대해서 물어보았다. 또한 학생들이 좋아하는 음료와 1주일에 술마시는 횟수를 조사하 였으며 한달에 용돈을 얼마 쓰는가를 분석하였다. 이러한 분석을 통하여 대학생들이 부산에 대해 어 떻게 생각하고 또 어떤 생활을 하고 있는가를 부분적이지만 알 수 있었다. 그리고 이러한 연구가 계 속되어 축적이 되면 훗날 부산을 이해할 수 있는 좋은 자료가 될 것으로 기대된다.

자궁외 임신의 임상적 고찰

김대중,박성훈,정혁 조선대학교 부설 의학연구소 2000 The Medical Journal of Chosun University Vol.25 No.1

Background : This study is a clinical evaluation and statistical analysis on the cases of ectopic pregnancies who were surgically treated and histopathologically confirmed at the department of obstetrics and gynecology at Chosun university from January, 1995 to October, 1999. Results : 1. The hospital incidence of ectopic pregnancy was 1 in 10 deliveries and the most frequently age group was in 30~34 years of ages(33.3%). 2. Nulligravida was in 22.2% and the percentage of cases who had 1, 2, and 3 or more artificial abortion were in 30.0%, 19.8%, and 28.0% respectively and nullipara was in 35.4% and the percentage of cases who had 1, 2, and 3 or more deliveries were in 26.3%, 24.7%, and 13.6% respectively. 3. A previous history of appendectomy was in 12.3% and other abdominal surgeries were in 17.4%, pelvic inflammatory disease in 5.8%. 4. On symptomatology skipped menses was observed in 87.2%, lower abdominal pain in 86.0%, and bloody vainal discharge in 60.9%. 5. The mean duration from the first day of the last menstrual period to the date of operation was about 7 weeks. 6. The urine pregnancy test was positive in 75.5% and culdocentesis in 94.2%, Average serum β -hCG(human chorionic gonadotropin) level was about 3,200mIU/mL. 7. The most common site of ectopic pregnancy was salpinx in 91.7%. In the cases of tubal pregnancy, the lesion was most commonly located at the ampulla portion(82.3%) and ruptured tubal pregnancies were in 54.3%. 8. The amount of intraperitoneal free blood was 101~500ml in 29.2%, 501~1000mL in 31.3% and 1001~2000mL in 26.4%.91. Other abnormal pelvic conditions were noted in 30.5% and adhesion was in 13.6%. 10. The operative procedures were salpingectomy in 80.7%, salpingo-oophorectomy in 6.5%, corneal resection in 6.2%, and were laparoscopic operation in 24.3%, laparotomy in 75.7%. 11. There was no fatal case in 243 ectopic pregnancy.