진주지역 아동 복지 시설에서의 피복환경에 대한 미생물 평가

정정숙,박선자,정덕화 대한보건협회 2002 대한보건연구 Vol.28 No.4

This study was conducted to assess the microbial level of cloth environment at five child welfare institutions(A, B, C, D, E) in Jinju District. Four major categories for experiment were personal hygiene, cloth hygiene of chilfren, cloth environment in indoor and kitchen which were involved thirteen minor items. Main assessment tool on this research was total bacteria count. Whereas total bacteria count at B child welfare institution was high as 1.96× 10^4CFU /100cm^2 in hands, hair hygiene was good at the same place. According to cloth hygiene of children, hygienic condition of E place was bad with a high level of bacteria counts from various items including socks, shoes. Total bacteria of indoor cloth environmemt at all child welfare institutions was beyond the standatd level, but indoor air was more clean than other items. In cloth environment of kitchen, dish cloth and apron of C place showed high level of total bacteria counts with 1.72×10^3 CFU/100cm^2 and TNTC, respectively. fungi were also screened from every items except hair, and detected as high frequency in socks of A, B, C and E places. Among them, B place was oftenly contaminated with fungi in various items such as socks, bedcloth, apron and rubber gloves. In conclusion, periodic surveillance on microbial assessment of cloth environment should be necessary for the safety of cloth environment at child welfare institutions, so more hygienic practice and education of staff members were also reinforced.

환기정도에 따른 수술실용 신발 종류가 수술실 오염에 미치는 영향 : How to Choose Suitable Shoes?

남경동,정혜선,박영신,원진희,주미자,성화신,이지혜,이병희,조경숙,배재춘 한국의료QA학회 2000 한국의료질향상학회지 Vol.7 No.1

Background : Various types of protective footwear have been used to minimize bacterial contamination in operating rooms. In recent years, debate has arisen concerning the need for use of such protective footwear. This study was designed to provide useful data about choosing shoes most suitable for the surgical environment. Methods : Between November, 1999 and January, 2000, we performed this experimental study by comparing effect of three types of shoes (i.e., disposable shoescover, operating room-restricted shoes, and ordinary shoes) on bacterial contamination of operating rooms equipped with two different ventilation systems (i.e., high air-change, low air-change) respectively. Data were collected during two-hour sham operations in which subjects and their activities were strictly standardized. Bacterial flora were sampled from the study area floor and air colony-counts were measured. Results : In experiments involving high air-change ventilation system, there was a significant difference of floor contamination between three types of shoes, but no difference of air contamination. Under low air-change system, there was a significant difference of both floor and air contamination between three types of shoes. Conclusion : The results show that protective footwear would be unnecessary in the operating room with high air-change ventilation system, but it is important to choose suitable shoes carefully under low air-change system. Therefore, the use of outdoor shoes can be considered under high air-change system, but it would seem sensible to apply their first use in less bloody operations at the day surgery center or out-patient department to prevent transfer of body fluid into the outside environment.

제1요수 불완전 하반신 마비 환자에서의 기능적 전기자극에 의한 훈련 증례보고

최현주,이수영,김종문,강선화,정순열,강곤,정진상 건국대학교 의과학연구소 1996 건국의과학학술지 Vol.5 No.-

Functional electrical stimulation(FES) is known to increase muscle bulk and strength and prevent muscle atrophy in complete paraplegic patients. And other benefits include peripheral adaptations which improve muscle endurance, girth, and appearance, as well as central circulatory adaptation which enhances aerobic(cardiopulmonary) capacity. Good candidates for FES include spinal cord injured patients who have clinically complete upper motor neuron lesion between T4-T12. But we experienced incomplete L1 paraplegic patient who has improved maximal knee extension power, endurance, circumference and cross-sectional area of the thigh and the shank after FES-induced exercise for 44 weeks. So we recommend more trial of the FES-induced exercise to not only complete but also incomplete lumbar paraplegic patients.

Effects of Antenatal Magnesium Sulfate Exposure on Oxygen Support in Preterm Neonates

( Seon Hwa Chung ),( Hye Sook Im ),( Jae Eun Lee ),( Meong Hi Hahn ),( Ki Hoon Ahn ),( Geum Joon Cho ),( Sun Chul Hong ),( Min Jeong Oh ),( Hai Joong Kim ) 대한산부인과학회 2015 대한산부인과학회 학술대회 Vol.101 No.-

Sonographically accessed funneling of the uterine cervix as a predictor of successful labor induction

( Seon Hwa Chung ),( Mi Kyung Kong ),( Eui Hyeok Kim ),( Sang Won Han ) 대한산부인과학회 2015 Obstetrics & Gynecology Science Vol.58 No.3

Objective The Bishop score and length of the uterine cervix are good predictors of successful labor induction. However, little is known about the association between the funneling of the uterine cervix and successful labor induction. The study aimed to evaluate cervical funneling as a predictor of successful labor induction. Methods This study was designed as a prospective observational study. Subjects who delivered a baby by labor induction were enrolled in the study from July 2011 to August 2013. Cervical funneling and length were examined with transvaginal ultrasonography. The Bishop score was rated by digital pelvic examination. Results A total of 163 primigravida women were recruited for the study. Of these, 137 participants (84.0%) delivered vaginally by labor induction. Cervical funneling was observed in 93 women (57.1%). Successful labor induction was significantly higher in patients with cervical funneling than those without it (91.4% vs. 74.3%, P<0.01), and was significantly associated with cervical funneling, as well as the Bishop score and cervical length. In a multivariate analysis, cervical funneling was an independent predictor for successful vaginal delivery by labor induction ( odd ratio, 2.70; 95% confidence interval, 1.02 to 7.10; P=0.04). However, the Bishop score and cervical length had no association with successful vaginal delivery. Conclusion This study showed that cervical funneling could be a predictive marker for vaginal delivery during labor induction.

Postpartum maternal morbidity : Extent for delivery modes, parity and recovery.

( Seon Hwa Chung ),( Kyung Jin Eoh ),( Euy Hyuk Kim ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.98 No.-

To reveal proper management for puerperium women by comparing between delivery modes, parity for postpartum maternal morbidity. Questionnaire survey of postpartum patients who delivered in Ilsan hospital. Postpartum problem for fatigue, breast problem, piles, headache, anxiety/depression, constipation, stitches breaking down, UTI/urinary incontinence. Total 205 women were involved in this survey at 1month and 1 to 3 months after delivery. They reported themselves maternal morbidity, recovery level, breast feeding or not and weight loss amount. Total 205 postpartum women were participated this study. Most of postpartum women in both VD and CS complaint fatigue feeling among the various problem in puerperium. Recovery level (17%) was similar between VD(vaginal delivery) and CS (Cesarean section). Multipara women feel more better than primipara after delivery regardless of delivery modes. Maternal morbidities in puerperium are broad and tend to easily neglect in comparison with perinatal care. The health provider and the health care center have to know exactly the problems to take proper puerperium managements and return to pre-pregnancy status.

고욤잎 추출물과 분획물의 항산화 및 alpha-glucosdiase 저해 활성 및 플라보노이드 화합물의 정량

김선영(Seon-Young Kim),김상준(Sang Jun Kim),김지애(Ji-Ae Kim),김다혜(Da Hye Kim),곽설화(Seol Hwa Kwak),정창호(Chang Ho Chung),전인화(In Hwa Jeon),장선일(Seon Il Jang),정승일(Seung-Il Jeong) 한국생명과학회 2014 생명과학회지 Vol.24 No.9

고욤잎은 주로 음료로 소비되지만 아시아 지역에서는 민간약품으로서 사용되었다. 본 연구의 목적은 고욤나무잎 추출물의 생리 효능을 평가하고자 하였다. n-Hexane, CHCl₃, EtOAc (EA), n-BuOH을 포함한 다양한 용매 분획을 고욤잎의 MeOH 추출추출부터 얻었다. 식물성 페놀과 플라보노이드의 함량은 강력한 생물학적 활성과 의약소재 결정에서의 필요성이 증가하고 있다. 본 연구에서, EA 분획의 총 폴리페놀과 총 플라보노이드 함량이 다른 분획에 비해 높았다. 고욤잎 추출물의 생리 효능으로서 항산화 효능은 DPPH, ABTS 라디칼 소거능과 SOD 활성을 통하여 확인하였고, 항당뇨 효능은 α-glucosidase 활성 억제를 통해 확인하였다. 높은 총 폴리페놀과 총 플라보노이드 함량을 보인 EA 분획에서 높은 항산화 활성과 α-glucosidase 억제활성을 보였다. EA 분획은 컬럼 크로마토그래피로 추가 정제하여 8개의 분획을 얻었다. 극성이 높은 분획물에서 항산화 효능 및 α-glucosidase 저해활성이 높게 확인되었다. 효능이 높게 확인된 분획 및 정제물에서 quercetin-3-rutinoside, kaempferol-3-O-glucoside, myricetin, luteolin, kaempferol을 포함한 플라보노이드 함량을 HPLC를 이용하여 분석하였다. 이러한 결과는 고욤잎 추출물이 항산화 및 항당뇨 효능을 가지며 천연 건강 제품의 소재로서 가능성을 제시하는 것이다. Persimmon leaves were commonly consumed as beverages, but were also used as popular folk medicine in Asia. The purpose of this work was to assess the biological activities of Diospyros Lotus L. extracts (DLLE). Various solvent extracts, including n-Hexnae, CHCl₃, EtOAc, and n-BuOH fractions, were obtained from the methanol extract of Diospyros Lotus L. leaves. The increasing interest in the powerful biological activity of plant phenolics and flavonoids outlined the necessity for determining their content in medicinal herbs. In this study, the total polyphenol and flavonoid contents (TPC and TFC) in the EA fraction were higher than those of other fractions. The biological activities of DLLE were tested using the 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2’-azino-bis(3-ethylbenzothiazoline-6- sulfonic acid) diammonium salt (ABTS) radical scavenging activity assay, as well as superoxide dismutase (SOD) activity as an anti-oxidant effect and α-glucosidase inhibitory activity as an anti-diabetic effect. The EA fraction with high TPC and TFC values showed the highest anti-oxidant effect and high α-glucosidase inhibition. The EA fractions were further purified into eight fractions using open column chromatography. Higher anti-oxidant and anti-α-glucosidase activity were observed in polar fractions. The content of the flavonoids, including quercein-3-O-rutinoside, kaempferol-3-O-glucoside, myricetin, luteolin, and kaempferol, were analyzed in effective fractions using high-performance liquid chromatography (HPLC). The results suggest that DLLE have anti-oxidative and anti-diabetic effects and thus, have the potential as anti-diabetic materials and as a source for natural health products.

HBV : O-009 ; Poor durability of entecavir effectiveness: Extended data of the five year`s treatment experience

( Chung Hwa Park ),( Hee Yeon Kim ),( Do Seon Song ),( Myeong Jun Song ),( Nam Ik Han ),( Young Sok Lee ),( Si Hyun Bae ),( Jong Young Choi ),( Seung Kew Yoon ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.-

Background: Entecavir, first-choice antiviral agent for treatment of chronic hepatitis B (CHB), is well known of its efficacy during treatment, but still its durability of effectiveness after withdrawal is still uncertain. Here, the extended data of the entecavir durability is reported. Methods: Retrospective study was done from adult patients who took entecavir for at least 3 months, prescribed from Jan., 2006 and stopped before Dec., 2010. Complete virologic response (CVR) was defined as serum HBV DNA < 300 copies/mL and virologic relapse (Vr) as ≥ 104 copies/mL after achieving CVR. Results: Among total 1366 patients, CHB patients without decompensation who took entecavir as a first-line antiviral therapy, whose CVR was achieved followed by a period of consolidation and who had follow-up lab data after cessation were 53 (3.8%). The consolidation period varied throughout the patients from 0 to 1030 days. Cumulative relapse rates at months 3, 6, 9 and 12 after cessation of entecavir were 15%, 56%, 78%, 80%. Age and DNA titer at starting antiviral therapy was shown to be the predictive factors for relapse. None of the patients of age over 50 showed durable effectiveness (p=0.02), and DNA titer over 108 copies/mL showed higher relapse rates (p=0.013). Conclusions: Effectiveness of entecavir is not so durable in either HBeAg-positive or negative patients, and is not even dependent on consolidation duration. Treatment duration may even need to be extended in patients over fifty or whose serum HBV DNA titer is ≥ 108 copies/mL at initiation.

Biomechanical Analysis of the Different Classifications on Hurdle Step Test in Functional Movement Screen

Chung, Dong-Hwa(정동화),Lee, Young-Seon(이영선),Ki, Jae-Seok(기재석),Hah, Chong-Ku(하종규) 한국웰니스학회 2018 한국웰니스학회지 Vol.13 No.1

본 연구는 functional movement screen 허들 동작의 평가항목 관련 생체역학적인 변인에 근거한 자료와 전문가가 평가한 점수그룹 간의 차이를 검정하는 것이다. 한국 투척 국가대표 상비군과 대학선수 10명을 대상으로 3차원 영상과 지면반력을 획득하여 분석하였다. 결과는 다음과 같다. 첫째, 하지정렬을 나타내는 최대 엉덩관절각은 시상면의 국면 p2(p=.03<SUP>*</SUP>), 국면 p3(p=.04<SUP>*</SUP>), 국면 p5(p=.03<SUP>*</SUP>)과 수평면의 국면 p2(p=.049<SUP>*</SUP>), 국면 p3(p=.01<SUP>*</SUP>), 국면 p5(p=.00<SUP>*</SUP>), 국면 p6(p=.02<SUP>*</SUP>)에서 통계적으로 유의한 점수그룹 간 차이를 나타냈으나, 3차원의 최대 무릎관절각은 모든 국면에서 점수그룹 간 통계적으로 유의한 차이를 나타내지 않았다. 그리고 최대 발목관절각은 시상면의 p2(p=.01<SUP>*</SUP>)을 제외한 나머지 국면에서는 점수그룹 간 통계적으로 유의한 차이를 나타내지 않았다. 둘째, 요추의 움직임을 나타내는 절대 몸통각의 3차원 ROM은 모든 국면에서 통계적으로 유의한 점수그룹 간 차이를 나타내지 않았다. 셋째, 신체 밸런스를 나타내는 좌우 어깨 수직변위 차이는 국면 p6(p=.01<SUP>*</SUP>)을 제외하고 모든 국면에서 통계적 유의한 점수그룹 간 차이를 보이지 않았으며, 수직 지면반력의 국면별 비대칭지수는 점수그룹에서 일관된 경향을 보이지 않았다. 결론적으로 FMS의 허들 동작에서 전문가의 시각적 평가방법은 생체역학적 변인에 근거한 결과와 일치하지 않았다. 이를 보완하기 위하여 FMS의 평가체계를 시각적 평가방법과 생체역학적 변인을 고려한 새로운 통합평가체계에 관한 연구들이 필요하다. In order to verify the difference score groups assessed by experts and materials based on biomechanical variables related to the evaluation items of functional movement screen hurdle motions, three-dimensional images and ground reaction force were acquired from ten Korean national team and collegiate throwers, and upon analysis, the summary and conclusion is as follows. First, the maximum hip joint angles representing the lower limb alignment were statistically significant different in the p2 (p=.03<SUP>*</SUP>), p3 (p=.04<SUP>*</SUP>), and p5 (p=.03<SUP>*</SUP>) of sagittal plane and p2 (p=.049<SUP>*</SUP>), p3 (p=.01<SUP>*</SUP>), p5 (p=.00<SUP>*</SUP>), and p6 (p=.02<SUP>*</SUP>) of the horizontal plane. The maximal knee angles of three dimensions did not show statistically significant differences between the scores in all phases. Second, the three-dimensional ROMs of the absolute trunk angle representing the lumbar movement did not show statistically significant differences between the scores in all phases. Third, asymmetric indices of the vertical ground reaction forces did not show a consistent tendency in the score groups. In conclusion, the visual evaluation method of the experts in the FMS hurdle movement did not agree with the results based on the biomechanical variables. To overcome this problem, it is necessary to carry out studies to convert the evaluation system of FMS into a new comprehensive evaluation system considering the visual evaluation method and biomechanical variables.

HBV : O-009 ; Poor durability of entecavir effectiveness; Extended data of the five year`s treatment experience

( Chung Hwa Park ),( Hee Yeon Kim ),( Do Seon Song ),( Myeong Jun Song ),( Nam Ik Han ),( Young Sok Lee ),( Si Hyun Bae ),( Jong Young Choi ),( Seung Kew Yoon ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1

Background: Entecavir, first-choice antiviral agent for treatment of chronic hepatitis B (CHB), is well known of its efficacy during treatment, but still its durability of effectiveness after withdrawal is still uncertain. Here, the extended data of the entecavir durability is reported. Methods: Retrospective study was done from adult patients who took entecavir for at least 3 months, prescribed from Jan., 2006 and stopped before Dec., 2010. Complete virologic response (CVR) was defined as serum HBV DNA < 300 copies/ mL and virologic relapse (Vr) as ≥ 104 copies/mL after achieving CVR. Results: Among total 1366 patients, CHB patients without decompensation who took entecavir as a first-line antiviral therapy, whose CVR was achieved followed by a period of consolidation and who had follow-up lab data after cessation were 53 (3.8%). The consolidation period varied throughout the patients from 0 to 1030 days. Cumulative relapse rates at months 3, 6, 9 and 12 after cessation of entecavir were 15%, 56%, 78%, 80%. Age and DNA titer at starting antiviral therapy was shown to be the predictive factors for relapse. None of the patients of age over 50 showed durable effectiveness (p=0.02), and DNA titer over 108 copies/mL showed higher relapse rates (p=0.013). Conclusions: Effectiveness of entecavir is not so durable in either HBeAg-positive or negative patients, and is not even dependent on consolidation duration. Treatment duration may even need to be extended in patients over fifty or whose serum HBV DNA titer is ≥ 108 copies/mL at initiation.