Anti-Inflammatory Effect of By-Products from<i>Haliotis discus hannai</i>in RAW 264.7 Cells

Rho, Ho-Seok,Kim, Hyang,Kim, Jung-Ae,Karadeniz, Fatih,Ahn, Byul-Nim,Nam, Ki-Ho,Seo, Youngwan,Kong, Chang-Suk Hindawi Limited 2015 Journal of chemistry Vol.2015 No.-

<P>Several reports promoted the potential of shellfish due to their ability to act as antioxidant, anti-inflammatory, and antimicrobial agents. Pacific abalone,<I>Haliotis discus hannai</I>viscera is, reported to possess bioactivities such as antioxidative stress and anti-inflammatory. In this study, anti-inflammatory potential of mucus-secreting glands from shell-shucking waste of<I>H. discus hannai</I>was evaluated using RAW 264.7 mouse macrophage cell model. Results indicated that presence of<I>H. discus hannai</I>mucosubstance by-products (AM) significantly lowered the nitric oxide (NO) production along the expressional suppression of inflammatory mediators such as cytokines TNF-<I>α</I>, IL-1<I>β</I>, and IL-6 and enzymes iNOS and COX-2. Also, AM was shown to increase expression of anti-inflammatory response mediator HO-1. Presence of AM also scavenged the free radicals<I>in vitro</I>. In conclusion, by-products of<I>H. discus hannai</I>are suggested to possess notable anti-inflammatory potential which promotes the possibility of utilization as functional food ingredient.</P>

Hepatoprotective and Antioxidative Activities of <i>Cornus officinalis</i> against Acetaminophen-Induced Hepatotoxicity in Mice

Lee, Nam-Hun,Seo, Chang-Seob,Lee, Ho-young,Jung, Da-Young,Lee, Jun-Kyung,Lee, Jin-Ah,Song, Kye Yong,Shin, Hyeun-kyoo,Lee, Mee-Young,Seo, Young Bae,Kim, Hokyoung,Ha, Hyekyung Hindawi Publishing Corporation 2012 Evidence-based Complementary and Alternative Medic Vol.2012 No.-

<P>The fruit of <I>Cornus officinalis </I>Sieb. et Zucc. is commonly prescribed in Asian countries as a tonic formula. In this study, the hepatoprotective effect of ethanolic extracts of the fruit of <I>C. officinalis</I> (ECO) was investigated in a mouse model of acetaminophen- (APAP-) induced liver injury. Pretreatment of mice with ECO (100, 250, and 500 mg/kg for 7 days) significantly prevented the APAP (200 mg/kg) induced hepatic damage as indicated by the serum marker enzymes (AST, ALT, and LDH). Parallel to these changes, ECO treatment also prevented APAP-induced oxidative stress in the mice liver by inhibiting lipid peroxidation (MDA) and restoring the levels of antioxidant enzymes (SOD, CAT, and HO-1) and glutathione. Liver injury and collagen accumulation were assessed using histological studies by hematoxylin and eosin staining. Our results indicate that ECO can prevent hepatic injuries associated with APAP-induced hepatotoxicity by preventing or alleviating oxidative stress.</P>

성인 음낭수종의 치료로서 Window Operation의 효용성

서병욱,박영호,이남규,전윤수,김민의,김영호,송윤섭,구자현 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.1

We intended to determine the usefulness of window operation for adult hydrocele repair. We reviewed medical records of 132 patients from January 1995 to June 1998 with primary hydrocele and evaluated complications and recurrence rates of eversion and/or excision, plication, and internal drainage technique. Recurrence rate was highest in internal drainage technique as 85.2%, and those of eversion and/or excision and plication technique were 1.3% and 4%, respectively. Complication rate was highest in eversion and/or excision technique, and lowest in internal drainage technique. Although complication rate was lowest in window operation, this operation could not be successful due to high recurrence, and we suggest that this operation should be abandoned for hydrocele repair.

초등학교 교육과정과 교과서에 농업·농촌의 기능 및 가치 반영 방안

서우석,강대구,정남용,김재호,이윤조 한국농업교육학회 2006 농업교육과 인적자원개발 Vol.38 No.4

이 연구는 농업ㆍ농촌의 기능과 가치를 재정립하고 이를 초등학교 교육과정 및 교과서에 반영시킬 수 있는 방안을 제시하는데 그 목적이 있었다. 이를 위하여 먼저 선행연구 고찰을 통하여 농업ㆍ농촌의 기능과 가치를 재개념화하고, 이를 토대로 내용 분석 틀을 개발하여 초등학교 교육과정 및 교과서를 분석 하고, 그 결과를 토대로 교육과정 및 교과서에 반영시키기 위한 방안을 제시하였다. 그 주요 결과는 다음과 같다. 첫째, 농업ㆍ농촌의 기능과 가치는 크게 자연환경적 기능(수자원 함양 기능, 환경정화 기능, 생태계 보전기능, 자연재해 방지 기능), 사회문화적 기능(전통문화 보전 기능, 정서의 순화 기능, 자연학습의장 제공 기능), 사회경제적 기능(농산물 공급 기능, 직업 기회 제공 기능, 국토의 균형발전 기능, 타 산업에의 기여 기능)으로 분류하였다. 둘째, 농업ㆍ농촌의 기능과 가치를 바탕으로 초등학교 교육과정 및 교과서를 분석한 결과, 전 학년에 걸쳐서 자연학습의 장 제공 기능과 전통문화 보전 기능이 높게 나타났고, 그 다음으로는 농산물 공급기능과 정서순화기능이 높게 나타났다. 반면에 수자원함양기능과 환경정화기능은 상대적으로 낮게 나타났다. 셋째, 내용분석을 토대로 교과의 성격을 고려하여 각 교과별로 농업ㆍ농촌의 기능과 가치를 반영시킬 수 있는 방안을 제시하였다. 마지막으로, 각 교과별로 농업ㆍ농촌의 기능과 가치 반영 방안을 체계적으로 이행하기 위한 행ㆍ재정적 지원 방안을 교육과정 개발 측면, 교과서 개발 측면, 교육과정 운영측면, 정책적 지원 측면으로 구분 하여 제시하였다. The purpose of the study is to suggest the strategies for incorporating the roles and values of agriculture & rural areas as a part of the national curriculum and elementary school textbooks. For this purpose, this study was conducted as follows; First, we reclassified the roles and values of agriculture & rural areas after critically reviewing literature: environmental conservation functions, socio-cultural functions and socio-economic functions. Second, based on the new classification, we develop a framework for analyzing the national curriculum and elementary school textbooks. The functions of rural areas as places for learning about nature and purifying emotion and the importance of agriculture in providing agricultural product were frequently presented but the functions of sustaining water resources and environmental purification were relatively less presented in the national curriculum and elementary school textbooks. Third, we suggested strategies for incorporating the roles and values of agriculture & rural areas in the national curriculum and elementary school textbook based on the analysis. Finally, we suggested necessary administrative and financial assistance to systematically and effectively implement the suggested strategies for developing a new curriculum and textbooks as well as implementing the curriculum.

유한요소법과 경계요소법을 이용한 음향트랜스듀서의 음향방사 특성 해석

남효덕,서희돈,고영준,장호경 嶺南大學校 工業技術硏究所 2001 工業技術硏究所論文集 Vol.29 No.2

The acoustic characteristics of the acoustic transducer was simulated by using the finite element method(FEM) and boundary element method(BEM). After meshing the inside closed boundary of the acoustic transducer, pressure gradients, isobaric lines, directivity characteristics and acoustic impedances were calculated by using the FEM and characteristics of 3-D free field sound pressure, directivity characteristics and radiation efficiency were simulated by using the BEM. It was shown that the usefulness of the design and the fabrication for the acoustic transducer from the results.

초등학교 과학 수행평가에 대한 교사의 인식

서승조,조태호,백남권,박강은,김성규,박장서 晋州敎育大學校 科學敎育硏究所 2001 科學敎育硏究 Vol.27 No.-

The purposes of this study are to examine how Science Performance Assesment is being well conducted in elementary schools and to check the teachers' awareness through surveying the actual condition. To achieve this purpose, the author, in this study, distributed questionnaire developed by researcher under supervision of academic advisor to the elementary school teachers in Gyeongnam province. Based on the data. the research results were mainly analyzed by the statistical method using Chi-square test. The survey was consisted of questions which was designed to perceive teachers' awareness about elementary school science performance assessment. The main findings of this study are summarized as follows', 1. Elementary teacher's are doing affirmative estimation about induction of performance assessment. 2. Most teacher are recognizing performance assessment right and teachers' understanding appeared high. 3. Material development of performance assessment is recognizing that people who have opinion which is special must develop. 4. The biggest problem of performance assessment fixing is recognizing that number of persons per class are many and amount of training courses is much also with the tribe during time. 5. It was recognizing positively whether it is in class improvement of performance assessment effect. 6. Teachers had awareness that confirm studies accomplishment degree through performance assessment, or will utilize to improvement material of teaching-learning method.

漢方藥劑의 品質評價와 藥效에 關한 硏究(第6報) : 元柴胡및 竹柴胡 水性엑스의 中樞抑制作用에 對하여 Central Depressive Action of Bupleurum Falcatum and Bupleurum Longiradiotum

徐成勳,洪南斗,權昌鎬,金壽億 慶熙大學校 1988 論文集 Vol.17 No.-

The effects of the aqueous extracts of Bupleurun falcatum and Bupleurum longiradiotum on the central nervous depressive action were studied by the behaviroral pharmacological method. The roots of Bupleuri radix was extracted with distilled water for 8 hours. Effect of extracts were tested by spontaneous movement activity using photoelectric method, openfield method, sloped plate method, rotarrod method and extension of hypnosis time induced with sodium phenobarbital and pentobarbital sodium, and defense against convulsive action induced with strychnine, picrotoxine and electric shock seizure in mice and rats. Extracts was found to pharmacologically expect above various action similar to these of diazepam but action of samples weaker than that of diazepame. Extracts of Bupleurum longiradiotum was definitely superior to the Bupleurum extracts in the central nervousderpressive action.

협동학습이 자연과 학업성취 및 과학태도에 미치는 효과

서승조,백남권,조태호,김용진 晋州敎育大學校 科學敎育硏究所 1999 科學敎育硏究 Vol.25 No.-

The purpose of this study is to manifest the effect of STAD cooperative learning which has not yet been explained in cooperative learning of an elementary school, on the academic achievement in science and science related attitudes. Therefore, in order to achieve that purpose, I established the following issues of study. First: What effect does STAD cooperative learning have on the elementary school students' academic achievement in science? Second: What effect does STAD cooperative learning have on the elementary school students' science related attitudes? The results of the study are as follows. First, while it was proven that the effect of STAD cooperative learning on academic achievement in science had no significant difference in pre·post achievement levels for both the experimental group and the control group, the experimental group showed larger changes in the mean value than control group; it can be inferred that classes to which cooperative learning is applied is more effective than traditional science classes. Second, in regard with the effect of STAD cooperative learnign on science related attitudes, while there was a significant difference between the experimental group and control group in pre examination, there was no significant difference, which means STAD cooperative learning does have effect on science related attitudes. In conclusion, the results of this study manifest that STAD cooperative learning is effective for science related attitudes in elementary school science classes, and assume that it can be effective for academic achievement.

초등학교 교사들의 과학과 실험연수에 대한 의식 조사

서승조,조태호,백남권,김성규,박강은,정순호 晋州敎育大學校 科學敎育硏究所 2001 科學敎育硏究 Vol.27 No.-

This study investigated the perceptions of elementary school teachers' on the science experimental training course using closed-form questionnare. 437 elementary school teacher, 21 school, 14 cities and counties in Gyung Nam province were selected as the objects for researching these matters. The results were as follows; First, without system and holding type teachers choose on the training not the same time but their ability freely. Second, to extend the trust the composition of place and instructor must be based on professor and research in the national university of education. Third, the composition of the text must be made of scientific growth based on important experimental activities teaching strategy, the using of materials. It must be increase multimedia training course on the science education. Fourth, the method of training course it must be happen on the experiment and discussion and it is necessary to grow up training level. Fifth, the type of training it must not give the score. Therefore it will be free and comfortable without difficulties. In the results, the improvement of science experimental training course is compatible on the purpose and it will help on the science teaching-learning.

초등학교 과학과 에너지영역의 STS 내용 변천

서승조,조태호,백남권,김성규,박강은,정인재 晋州敎育大學校 科學敎育硏究所 2001 科學敎育硏究 Vol.27 No.-

This research compared and analyzed the content ratio of the STS (Science-Technology-Society) Education and subjects and types of learning activities to determine the characteristics of STS education in science classes of elementary schools. In the 5th curriculum, the STS-related content on energy section took up 6.6% , in the 6th curriculum, compared with that of the 5th, the STS content ratio on the energy section increased 7.9% and the STS content on the energy section in the 7th curriculum showed an increased 20.8% proportion. Comparing the main subjects of the STS in the energy section for the science class according to curriculum in the 5th, they obviously have influenced technological development, energy, the development of space studies, and sociology of science, in that order. In the 6th curriculum. compared with that of the 5th, the energy section decreased and the sociology of science increased much. There were no significant changes in other subjects. In the 7th, the STS elements were distributed evenly but the extent of the STS main subjects reduced compared to that of the 6th. The STS education activities represented in science textbooks of elementary schools were mainly executed through discussion, research activities, and actual activities. Other activities such as role-playing, simulation tests, problem solving and decision making, data analysis, research design, case studies, etc. were hardly made.