Mirizzi 증후군의 변형된 분류와 치료

김형철,강길호,채만규,김성용,백무준,이문수,박상흠,이문호,김창호,송옥평,조무식,박희주 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Purpose : The Mirizzi syndrome is relatively rare and preoperative diagnosis of this disease is difficult. In 1978, Morelli suggested the subclassification of the Mirizzi syndrome into acute or chronic form. We experienced 5 cases of acute form. We analysed clinical features, preoperative radiologic findings and operative findings of 18 cases including acute forms which were diagnosed as Mirizzi syndrome and should suggest the modified classification of Mirizzi syndrome for choice of appropriate treatment. Method : From January 1995 to December 1998, 18 cases, of which 8 cases were diagnosed at Soonchunhyang University Chunan Hospital, and 10 cases were reported in the Korean Journal were retrospectively analysed with regard to clinical features, preoperative radiologic findings and operative findings. According to the clinical features, whole cases were divided into type Ⅰ(acute form) and type Ⅱ(chronic form) and then each type of cases were subclassified according to preoperative radiologic findings and operative findings. Results : Of 18 cases there were 5 cases in type Ⅰ(27.8%), 13 cases in type Ⅱ(72.2%). Type Ⅱb was most common. Type Ⅰa cases were treated only with cholecystectomy. We applied cholecystectomy, T-tube choledochostomy and patch technique in type Ⅰb and thpe Ⅰc cases. Cholectystectomies including removal of gallstones and internal drainage procedures were done in type Ⅱ chronic forms. Conclusion : The acute form(Type Ⅰ) of Mirizzi syndrome was suggested by Morelli might be subclassified into typeⅠa,Ⅰb and Ⅰc following the presence of the necrotic defect in common hepatic duct. Through the modified classification of Mirizzi syndrome based on clinical feature, preoperative radiologic findings and operative findings, we can choice appropriate treatment.

프레스금형의 드로비드설계에 관한 실험적 연구

송준호,유호영,김진무 울산대학교 1994 공학연구논문집 Vol.25 No.2

정사각형 용기의 Deep Drawing 성형성 실험을 다양한 작업조건하에서 수행하였다. 본 연구에서는 재료의 유동상태와 판두께의 국부적 변화량을 성형성의 척도로 사용하였으며, Photo-etching 방법을 이용하여 이들을 측정하였다. Draw Bead의 크기, 블랭크 홀더력의 크기 및 윤활상태의 변화에 따른 정사각형 용기의 둘레방향, 대각선방향 및 반경방향으로의 판두께 변화량과 재료의 유동상태를 실험적으로 분석하였다. Experiments on the drawability of squared boxes have been performed under various working conditions. In the present work, the pattern of material flow and the local change in the thickness of shell are used as the measures of drawabilitiy and they are measured using the photo-etching technique. The size of draw bead, the magnitude of blank holding force and the condition of lubrication have been changed and their effects on the pattern of material flow and the thickness of shell along the circumferential, diagonal and radial directions of the squared boxes have been analyzed experimentally.

Prednislolne이 골조직에 미치는 영향에 관한 형태학적 연구

송혜정,김무강,김원식,이영호 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.1

To study the effects of corticosteroids to the bone tissues, author grouped young(3 weeks affter birth) and adult ICR mouse by dosage, injected intramusculaily prednisolone, a series of corticosteroids, to posterior leg during 6 weeks per day, obtained femurs and tibias, measured the lengths of tibias and femurs. The portions of the distal end of tibial crests were cross-sectioned, general H-E stain was perpormed. The adjacent distal portions of femoral neck were sectioned longitudinally, observed endosteal surface by scanning electron micrscope The results were followings: 1. The adult group injected by large dosage (0.56mg/100g body weight/day) and the young group injected by small dosage(0.14mg/100g body weight/day) from 3 weeks after birth were significantly shorter than the normal group according to statistics. And the adult group injected by small dosage (0.14mg/100g body weight/day) was not different from normal group according to statistics. 2. In the light microscopic sutdy, the adult group injected by large dosage decreased in bone mass of compact bone severely, the adult group injected by small dosage changed a little grade. The young group injected by small dosage from 3 weeks after birth was not severe in bone change, but bone thickness decreased. 3. In the scanning elctron microscopic study, the adult group injected by large dosage and the young group iniected by small dosage from 3 weeks after birth decreased in trabeculae. The trabeculae of the adult group injected by small dosage were decreased slightly. 4. Integrating above all, the changes by prednisolone injection osteoporosis, of young period were more severe than those of adult, too.

흰쥐 심방벽 소혈관 분포의 특징

이무삼,이흥철,송창호,고병문,김봉천,정철현 대한해부학회 1995 Anatomy & Cell Biology Vol.28 No.1

전신마취 후 발생한 악성고열증 환자의 치료 경험

이근무,정승환,이정한,정순호,최영균,김영재,신치만,박주열,이영민 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Malignant hyperthermia is the disorder of calcium regulation within skeletal muscle associated predominantly with anesthesia. It is triggered by volatile anesthetics and depolarizing neuromuscular blocking agents. We experienced a case of malignant hyperthermia. 50 years old female patient was transferred to our emergency room that she was developed tachyarrhythmia and high fever. She was taken arthroscopic examination under the general anesthesia with enflurane and succinylcholine. We suspected malignant hyperthermia and promptly treated her with dantrolene sodium. She was developed disseminated intravascular coagulopathy and acute renal failure then we were intensive care to her. She was discharged without sequela. We experienced successful management of malignant hyperthermia.

中原郡 東良面 湍東里一帶 沃川系의 地質構造 硏究

金石鎬,宋武永 忠南大學校 環境問題硏究所 1988 環境硏究 Vol.6 No.2

The study area consists of Precambrian Bakdalryong and Busan metamorphic rocks, the Chosun Super Group, the Ogcheon Group. It is now thought that the meta sediments of the Ogcheon Terrane have gone through at least three periods of major deformation. The deformational events are designated as D1, D2, D3, and the folds associated with each deformational event as F1, F2, F3. Most fold structures in the area of the secondary generation fold and cleavage indicate N to NE vergence. Most mesoscopic folds are isoclinal folds whose axes are coaxial macroscopic fold axes. The Seochangri Formation contacts with the Busan Metamorphic rocks by Sondong Fault. Quartzite and Limestone Formation of Chosun Super Group contacts with the Seochangri Formation by Tandong Fault. Jubongsan Fault is located between Munjuri and Hwanggangri Formation.

조류에 실험적으로 감염시킨 Rickettsia tsutsugamushi의 증식.

구영무,송호연,이강순 순천향대학교 1992 논문집 Vol.15 No.2

For the survey of possibility of the inapparrent infection of R. tsutsugamushi in bird, we infected the chicken with suspension of R.tsutsuggamushi via intraperitoneal and subcutaneous routes. We observed the chicken on various vital signs and examined indirect immunofluorescent staining, pathologic and electron microscopic finding on liver and spleen of chicken. The result were as follow ; 1. We can;t detect the any abnormal finding in chicken infected with suspension of R.tsutsugamushi, except the highly increased levels of SGOT and SGPT when compared to control group. 2. In indircet immunofluorescent staining, antibody titers to R.tsutsugamushi in serum of infeted chickens were increased rapidlly after 2-3 weeks of infection. Also, positive fluorescent cells were observed in liver and spleen of infected chicken. 3. Patholigic finding of liver and spleen in infected chicken were showed inflammatory cells infiltration and vasculitis, especially endothelial cells lining small blood vessel were showed marked proliferation and degeneration. 4. In electron microscopic finding, R. tsutsugamushi were observed mainly in endothelial cells lining blood vessels of liver and spleen. In conclusion, the inapparent infection of R. tsutsugamushi in chicken was conformed and these results suggest the need of move wide scale of survey in wild bird and migrant birds in near future.

Pocine Adenovirus-3의 E1B Region의 鹽基序列 分析

朴鍾賢,宋載永,李重馥,玄芳勳,安東濬,車相昊,裵用泰,姜永源,Reddy, P S,全茂炯,安壽煥 충남대학교 생물공학연구소 1999 생물공학연구지 Vol.7 No.-

돼지 아데노바이러스(PAV-3). 6618주의 EIB region이 包含되어 있는 map unit 4.0에서 9.7까지의 유전자에 대한 1,984 bp의 염기서열을 決定하였으며, 이 結果를 알려진 여러 아데노바이러스 유전자와 비교하여 다음과 같은 결과를 얻었다. 1. PAV-3의 EIB유전자는 10개의 ORF로 구성되어 있으며, 그 중 아데노바이러스의 단백질과 유사성이 있는 것은 ORF1, ORF2 및 ORF3이었다. ORF1은 Ad41의 19kd 와 BAV-2에서의 EIB ORF2에서의 아미노산의 一致率은 각각 32%와 31%이었다. 2. ORF2는 Ad2 55kd protein과 tupaia adenovirus 44kd protein가 각각 34%로 아미노산 一致率이 가장 높았으며, Ad41의 52kd protein. BAV-3의 EIB ORF3에서도 33%의 一致率을 보였다. 3. ORF1은 61-666 uncleotide (606 bp), ORF 2에서는 429-1,850 uncleotide (1,422 bp)의 부위로 각각 202, 474 a.a로 構成되었으며, 예상되는 분자량은 20 kd와 52 kd이었다. 4. ORF3는 hexon-associated pIX유전자로 추정되며 내부에 1개의 polyadenylation signal(ATAAA)이 1938-1942 uncleotide에 위치하였으며, 이 부위는 TATA box (1937-1942 uncleotide)와 중복되어 존재하였다. Porcine adenovirus type 3 (PAV-3) does not cause severe infection in pigs. Adenovirus has been suggestive of live vaccine vector carrying foreign gene. One of insertion regions is delayed early (EIB) region. However, EIB region of PAV-3 has not been molecularly characterized to date. Nucleotide sequence of EIB of PAV-3 was determined. The EIB region was composed of 1,984 bp and located between 4.0 and 9.7 map units. Three potential open reading frames(ORFs) with low level of homology to other adenoviruses and a polyadenylation signal were identified in the rightward direction of genome. The nucleotide and the predicted amino acid sequences of EIB were compared to those of human and animal adenoviruses. One of the three potential ORFs. ORF1 encoded a polypeptide homologous to bovine adenovirus type 2(BAV-2) ORF2 and human adenovirus type 41(Ad41) 19 kd protein. ORF2 encoded a polypeptide homologous to human adenovirus type 2(Ad2) 55 kd protein, bovine adenovirus type 3(BAV-3) ORF3 and porcine adenovirus type 4(PAV-4) ORF2. The predicted protein of ORF1 had homology to those of Ad41 and BAV-2 with 32 and 31% respectively, whereas the deduced protein of ORF2 had homology to those of Ad2. BAV-3 and PAV-4 with 34, 33 and 29%, respectively.

물시멘트비 및 단위수량에 따른 고품질 재생잔골재를 사용한 재생콘크리트의 공학적 특성에 관한 실험적 연구

문형재,송민섭,김재환,장종호,김용로,김무한 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

The purpose of this study is to investigate and analyze experimentally and positively engineering properties of recycled concrete using high quality recycled fine aggregate according to w/c ratio and unit water contents. And it is intend to present fundamental data for the mix design and the improvement of quality. The results are as follows; According to the increase of W/C ratio, the addition ratio of superplasticizer was reduced, the strength of compressive and tensile showed low and carbonation depth and chloride penetration depth showed high. And according to the increase of unit water contents, the addition ratio of superplasticizer was reduced, the strength of compressive and tensile showed low and carbonation depth and chloride penetration depth showed high.

한반도 중서부 지각구조와 물성연구 전곡-연천 일대에 분포하는 백악기 화산암류의 고지자기 : Paleomagnetism of the Cretaceous Volcanic Rocks in Jeongog-Yeoncheon area

김광호,송무영 충남대학교 기초과학연구소 1995 연구논문집 Vol.15 No.-

추가령구조선의 지구조적 특성을 규명하기 위하여 전곡-연천 일대에 분포하는 백악기 응회암류와 용암류로부터 29개 장소에서 156개의 암석시료를 채취하여 고지자기를 연구하였다. 그 결과 응회암류로부터는 평균편각/평균복각=35.2°/54.1°(α_95=6.2)의 정자극기의 특징적방향이, 이를 관입 혹은 분출한 용암류로부터는 anomaly number 34에서 34r로 극성이 바뀌던 지자기천이기(약 83 Ma)의 방향이 측정되었다. 연구지역으로부터 구한 특징방향은, 동일 시기의 선행 고지자기자료와 비교할 때, 복각은 서로 유사하나, 편각은 약 13°크다. 이는 본 지역이 연직축 주위로 시계방향으로 약13°회전했음을 의미한다. 이와 같은 시계방향으로의 회전의 원인은 추가령구조선을 따라 일어난 우수향주향이동단층 운동일 것이다. 이 우수향의 단층 운동은 북북서 방향으로 이동하던 태평양판이 중기에오세부터 서북서로 그 운동방향이 바뀜에 따라, 북동-남서 방향의 압축력이 한반도에 작용했기 때문일 것으로 추론한다. Tp examine the geophysical characteristics of the Choogaryong tectonic line which runs in NNESSW direction from Weonsan through Jeongog to Seoul, paleomagnetic study was carried out from Late Cretaceous welded tuffs and andesitic rocks in Yeoncheon-Jeongog area. 156block samples from 29 site were collected. The welded tuffs yield a well define characteristic magnetization of normal polarity. A mean direction is declination=35.2°and inclination=54.1° with α_95=6.2°. All sites of the andesites extruded or intruded the tuffs have transitional directions prevailed during the polarity transition period between aonmaly number 34 and 33r (?? 83 Ma). The characteristic direction has mean declination 13°larger than those of the coeval paleomagnetic data reported from southeren Korea, suggesting a clockwise rotation about vertical axis. It is inferred that the clockwise rotation was resulted from right-lateral strike-slip fault (RLSF) along the Choogaryong tectonic line, and the RLSF was initiated from the oblique subduction of the Pacific plate which had changed moving direction from NNW to WNW in the Middle Eocene.