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      • 일개 대학병원에서 일년간 분리된 반코마이신 내성 장구균의 임상 분자역학적 연구

        송진영,김창억,김성욱,우흥정,김미란,이규만,이란,장미화,정희진,김우주 대한화학요법학회 2001 대한화학요법학회지 Vol.19 No.4

        목적 : 한강성심병원에서는 2000년 3월 반코마이신내성 장구균이 처음 분리되어, 원내전파를 막기 위한 노력을 하였으나, 분리가 지속되었다. 따라서 이에 대한 좀더 자세하고 객관적인 자료를 얻기 위해 본원에서 분리된 반코마이신내성 장구균에 대한 임상분자 역학적 연구를 시행하게 되었다. 방법 : 2000년 3월부터 2001년 2월까지 한림대학교 한강성심병원에서 분리된 장구균을 대상으로 디스크 확산법, 최소발육억제 농도등의 측정을 통해 반코마이신 내성여부를 확인하였으며, 반코마이신내성 장구균을 대상으로 PFGE를 시행하여 형별 분석을 하였다. 결과 : 분리된 균주는 총 32균주로 모두 E. faecium이었다. 항생제 내성 검사 결과 모두 Van A형이었다. PFGE 결과 1a형이 8검체, 1b형이 5검체, 2a형이 4검체, 2b형이 4검체, 3a형이 2검체, 3b형이 5검체였고, 그 외 4, 5, 6형이 각각 1검체씩이었다. 총 32균주 중 56%(18/32)의 균주가 같은 시기, 같은 병실에서 동일한 PFGE 형을 보이면서 분리되었다. 결론 : 반코마이신내성 장구균의 PFGE 분석 결과 여러 종류의 반코마이신내성 장구균이 유행하였음을 알 수 있다. 그러나 같은 기간, 같은 병실에서 분리된 균주의 PFGE 형이 같은 것이 상당수 있었다. 이는 반코마이신내성 장구균의 원내 전파가 있었음을 의미한다. 따라서 반코마이신내성 장구균의 전파의 발생 및 전파 방지를 위해서는 보다 효과적인 감염관리 활동이 필요할 것으로 생각된다. Background: Vancomycin-resistant enterococci(VRE) have been a rising problem worldwide. In March 2000, VRE was first isolated from a patient in Hangang Sacred Heart hospital. Although efforts to prevent transmission of VRE were performed, isolations continued. So molecular epidemiological study of VRE was done. Method : The minimal inhibitory concentration(MIC) to vancomycin and teicoplanin, and pulsed field gel electrophoresis(PFGE) pattern of VRE isolated from March 2000 to February 2001 were evaluated. Results : 32 VRE were isolated. All of the VRE were Enterococcus faecium and showed Van A resistance phenotype. We found out that a significant number of VRE isolated during same period and in same room, were same PFGE patterns. (18 cases/ 32 isolates= 56%) Conclusion: This study demonstrated the spread of VRE of same PFGE patterns. It suggests the nosocomial spreads of VRE.

      • 게임에서의 어머니-영유아 상호작용

        이미란 가톨릭상지전문대학 1997 논문집 Vol.27 No.1

        The purpose of the present study Is to provide and overview of research in the area of mother-infant games and to suggest the direction of future research In this area. This study reviews two theories that guide research in this area ; the theories of Bronfenbrenner's and Vygotsky's. Bruner and colleagues have the development of infants' abilities to play games, and then Bruner proposes that the caregiver provide a social "scaffold" for acquisition of skill. And, Hay and collaborators suggest four main features of social games : mutual invovement, turn-laking, repetition of a sequence, and nonliterality. The review of various research leads us to the following conclusions : 1) The analysis of infant behaviors In games show that Infants play an Increasingly active role as they matured. 2) Within early games the role of the mother is to facilitating the infant's ability to play. The author suggests longitudinal design of extended period for future research.

      • KCI등재후보

        서울지역 일부 과체중 및 적절체중 학령기 아동의 신체계측, 체지방률, 혈액지표 및 영양소 섭취 상태의 비교 분석 연구

        이정숙,이정윤,임현정,조미란,차성호,조여원 대한영양사협회 2003 대한영양사협회 학술지 Vol.9 No.4

        This study was carried out to compare the characteristics of the over weight elementary school students with those of desirable-weight children. Anthropometric parameters such as height, weight, BMI body fat percentile, triceps skin fold thickness were measured. Dietary assessment and blood analysis were performed. The average ages of over weight children and desirable-weight children were 10.9f2.5 and 10.2±2.8 years, respectively. The means body fat percentile of over weight children and desirable-weight children were 27.5±3.7% and 20.2± 3.8%. respectively. Plasma levels of TG. total cholesterol, LDL cholesterol, and HDL cholesterol of over weight children and desirable-weight children were 179.3±30.0. 104.9f26.6, 52.3f6.7 and 178.3±84.l㎎/dl and those of desirable-weight children were 86.1±43.5, 183.7f16.5, 101.0f2.1 and 67.7±20.0㎎/dl respectively. Plasma TG levels of over weight children were significantly higher than those of desirable weight chddren. On the other hand plasma HDL-cholesterol levels of over weight children were significantly lower than those of desirable-weight children Plasma levels of GOT ,and GPT were in normal range in both group. However, GPT level of over weight children was &her than that of desirable weight children. Plasma levels of albumin, globulin and BUN were all in normal range and no differences were found in both groups. Hematologic data did not show any difference between two group except WBC, KBC and Hgb levels which were significantly higher in over weight group than those of desirable-weight children. DAY nutrients intake of over weight children and desirable-weight children were very similar and they were around the Korean KDA levels for each nutrients. However, the intake of calcium of both groups were little over 50% of KDA. The consumption of d e b fiber was very low and the cholesterol intake was very high shorn that the habitual meals of Korean school children were not well balanced.

      • 공간 데이터베이스에서 질의 최적화를 위한 공간 분할 기법

        이미란,황환규 강원대학교 정보통신연구소 2002 정보통신논문지 Vol.6 No.-

        It is important to calculate the query result size for query optimization in spatial databases. When processing queries to the database, the computing cost of the query result size satisfying query conditions is so expensive. To solve the problem, the query result size estimation based on the summary data approximating the distribution and characteristics of the spatial data is very efficient. In this paper, we propose a spatial partitioning technique based on Maxdiff(V,A) whose performance is evaluated very efficient in one dimensional database. This paper proves the proposed partitioning technique is superior to previous ones through experiments.

      • KCI등재

        학동기 손자녀에 대한 조모의 역할수행 : 취업모가족과 비취업모가족 비교

        이미숙,조병은,강란혜 대한가정학회 2004 Family and Environment Research Vol.42 No.4

        The purpose of this study was to compare the grandmothers role performance toward their grandchildren in the elementary school between working and nonworking mother families. The subjects were 274 grandparent-grandchild pairs. The sbuctured questionnaires, from both grandmothers and grandchildren were collected in 2001. Using statistical technique such as factor analysis, t-test, Pearson's correlation, and multiple regression analysis, the major findings were as follows: 1) The level of the grandmothers' role performance is moderate in general. However, the grandmothers in working mother families perform surrogate mother roles more strongly than the grandmothers in nonworking mother families. 2) While contact between grandmother and grandchild is associated with the grandmother's role performance in working mother families, the grandmother's age and the closeness between grandmother and mother are related to the level of the grandmother's role performance in nonworking mother families. In conclusion, the grandmothers' role performance in working mother families was found to be more important in the supporting system than in nonworking mother families.

      • GIC를 활용한 도로중심의 건물주소 부여시스템

        이미란,김부영,옥철영 울산대학교 1999 공학연구논문집 Vol.30 No.1

        현행 국내 건물주소는 토지지번 중심으로 구축되어 교통 및 산업구조에서 물류비용을 증가시키는 요인이 되어 왔다. 내무부에서는 이러한 문제를 극복하기 위해 도로중심의 건물주소체계를 구축하고자 1997년부터 서울 강남구와 안양시를 대상으로 시범사업을 수행하였다. 시범사업에서는 먼저 도로의 길이를 건물수로 나눈 기초간격에 따라 기초번호를 구하고, 기초번호에 근거하여 수작업으로 건물주소를 부여하였다. 그러나, 이러한 방법에서는 기초간격이 도로길이와 건물수에 의해 산출됨으로써 도로사정에 따라 다르고, 수작업으로 부여한 도로중심의 주소체계를 검증하는 수단이 없었다. 본 논문에서는 시범사업에서 나타난 문제점을 해결하고 새로운 건물주소를 자동적으로 부여하기 위해 GIS를 활용한 도로중심의 건물주소 부여시스템을 제시했다. 이를 위해 시스템 설계의 기본원칙을 새롭게 설정하고, 공간정보와 속성정보가 구축된 GIS를 활용하여 시스템을 구현한다. 본 시스템에서 도로의 인접한 건물은 도로의 기점에서부터 건물까지의 도로경로거리와 방향에 따라서 건물주소가 부여되고, 골목길에 인접한 건물은 골목길의 시작점에 가상건물번호(X)를 부여하고, 골목길의 시작점에서부터 건물까지의 거리와 방향에 따라서 가상건물번호의 하위번호(n)를 부여하여 'Ⅹ-n'형태의 건물주소를 부여한다. 이와 같이, 도로에 인접한 건물과 골목길에 인접한 건물에 대해 서로 다른 방식으로 건물주소를 부여함으로써 차별화된 도로방식의 주소체계를 구축한다. 본 시스템은 일괄적으로 주소변환작업을 수행하며, 현재 사용하고 있는 토지지번 중심의 현주소와 도로중심의 신주소를 동시에 검색한다. Current lot-based building address system caused to increase the distribution cost of industry. Thus in order to decrease the cost, the Ministry of Home Affairs began to design and implement a pilot system for a road-based building address at KangNamGu and AnYang city in 1997. The pilot system calculated a basic number which was obtained from dividing the length of road by the number of building and assigned manually a road-based building address. But the basic length is different according to the length of road and the number of building and there is no verifying means of manually assigned address. This thesis presents a road-based building address assignment system using GIS that solves various problems in the pilot system and assigns a new building address automatically. This thesis establishes fundamental principles for the system design and implements the system using GIS in which spatial and attribute data are stored. In the system, the building address of road is assigned according to the direction and road path-distance from starting point of the road. The system assigns a virtual building address(X) to the cross point of adjacent road and alley, and assigns the building address(X-n) of alley to sub number(n) of the virtual building number according to the direction and distance from starting point of the alley. It assigns the building address of road and alley in different way so that it produces a distinctive road-based address organization. This system assigns a new building address in batch and searches current lot-based and new road-based address simultaneously.

      • KCI등재후보

        인지적 도제 모델을 활용한 글쓰기 지도법 연구 : 소설의 얼개 짜기를 중심으로 Focused on Planning Stories

        이미란 현대문학이론학회 2003 現代文學理論硏究 Vol.0 No.19

        The study aims at presenting an instructing method of planning story courses, based on the model of cognitive apprenticeship widely used in the social-cognitive theory of writing. Though a literary writing is a typical way of showing its writer's own experiences, it must also be in a farm of the systematic containers, so-called genre, in which human life common to all is contained. So it can not escape from the characteristics of the community's discourses. In this view point the sociocognitive writing theory can present an effective instructing method in story writing. In 'modeling' step, the first step of cognitive apprenticeship, the principles for choice of materials, mindmapping, outline making, theme defining, outline modifying and pattern making, plotting are explained and presented by instructors with appropriate examples to each activity. At this time the writings of existing writers' working courses and experiences can be effectively used. In this paper one of my stories, www.soriso.com, is used for the writing experiences. For the second step, 'discussion' step, while learners are finding materials, mindmapping and making outlines, the instructors answer the question from them or develop the learners' level with more level-up questions than they are in. After course the learners step into the oral writing, theme defining, outline modifying and pattern making, and plotting. The final step for the learner is title naming with his complete plot and presenting it to his colleague learners, In this course he can step into stage of performing self-planning stories automatically internalized. The first problem for learners of writing stories is 'what to write'. After finishing the course for planning stories by the social-cognitive theory of writing learners will be expected to start writing confidently with their complete and specific plots. Instructors' presentations and language-using assistances, and the experiences and ideas from the writing community through discussions with colleague learners will be expected to lessen the physical burden of writing story considerably, and to help the learners' creative writing by stimulating their imagination.

      • KCI등재후보

        창작론적 비평 방법에 관한 연구 : 이승우의 「도살장의 책」을 중심으로 Focused on Lee Seung-woo's <The Butcher's Book>

        이미란 현대문학이론학회 2005 現代文學理論硏究 Vol.0 No.24

        This paper aims, through critical methods based on fiction writing theory, at finding the reason why <The Butcher's Book>, written by Lee Seung-woo, cause an unhandy communication with readers. Good novel in terms of creative writing theory means that the writer's intention communicates fully with readers in an aesthetic completion as a literary work. If an analysis on a work is hard or impossible, it is because the text understanding is interrupted by the discrepancy between the writer's language and the readers' understanding. In <The Butcher's Book>, written by third person limited point of view and having almost not any distance between narrater and character, character's speech accords with nan-ater's, and that is also writer's. So it's not difficult to find the writer's intention. The writer intends to perform sacrificial rites. In spite of the writer's clear intention this work can not communicate easily with readers. It derives from the tensive relation between writer's presentation and his speech through writer's excessive desire. The first reason of the difficult communication with readers is from the discrepancy of the character 'Chonpyon' between the writer's desired and created in the work. The motive of this character, being distressed by dying books in the library and performing sacrificial rites by kidnapping and raping librarian, is not obvious. The second reason is that writer asks the character for improbable actions to realise his desire. `Chonpyon' has no reason to be a priest and his motive of raping goat-like girl has nothing to do with books' revival as well. The third reason is that the narrater's speech has no distance from the character to release writer's desire. The narrater having no distance from nconvincing character makes the character's action cooked up and makes readers feel coercion. The title in <The Butcher's Book>, its theme, and its background are so well matched. But the writer's excessive desire makes the work disunited and the communication with readers difficult by overwhelming the character, his action, and narrater's speech.

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