트레드밀 걷기 운동 시 무게부하의 차이가 호흡순환기능 및 대사기능에 미치는 영향

김용규,이채산,김자영,박미숙,김광중,이광호 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.20 No.1

The purpose of this study was to compare on cadiopulmonary and metabolism function of 10㎏ weight loading group(10 females) and W university students with non weight loading group(10 females. Each group did treadmill walking exercise for twenty minutes by the modified balke protocol. Heart rate(HR), systolic(SBP), MVO₂, and VO₂max were analyzed using 2×2(groups×during) repeated measures analysis of variance (MANOVA). And peak blood velocity(PBV) and MBV were analyzed by using 2×2(groups×during) repeated measures analysis of variance (MANOVA). Lactate and glucose were amalyed by separate 2×2 (groupxduring) analysis of variance(ANOVA). Results of this study suggest that: The change of HR, SBP and MVO₂ in experience and control group showed the significant(p<.05) increase during walking exercise. Variables between experience and control group showed not significant level. But VO₂ in each group showed the significant(p<.001) increase during walking exercise. Differenc among each group showed significant(p<.001) level. Lactate and glucose level in each group showed significant(p<.001, p<.05) increase during walking exercise. Differences among each group showed not significant level. PBV and MBV in each group significant(p<.001) increase during walking exercise. Difference among each group showed significant(p<.05) level. According to these results, weight loading walking exercise considering safety promotes to cardiovascular function and it is expected to be an effective exercise methods able to improve the physical inefficiency of long time walking type.

치아 수복용 불소함유 glass filler의 제조 및 특성

김대성,최세영,김경남,김광만,김중곤 대한치과기재학회 1998 대한치과재료학회지 Vol.25 No.3

The purpose of this study was the reaching test of restorative glass according to composition. Mixtures of SrF₂, CaF₂and SiO₂were fused in platinum crucible. The glasses were ground and fraction which passed through a 400 mesh (38㎛) sieve were collected. The powder specimens were analyzed by a DTA and XRD. Then powder specimen were inserted to D. I. water with various of dissolution time and composition at 37℃. Fluoride ion, cation release, solubility, and pH change were estimated. It was clear that the glasses were formed except S0.65. In S0.40, Tg, Ts, and Tc were 630, 672, and 813℃ respectively. In initial 0.5 hrs., amounts of released fluoride ion and cation were about 90% of total released amounts and released rate was decreased with dissolution time. Amount of released fluoride ion and cation were increased with decreasing SiO₂ in glass filler. And released rate was decreased rapidly by adding CaF₂. This was caused by structural variation in glass filler. Solubility was similar tendency with ion released. The pH of D.I. water was 4.5. But in intial 0.5 hrs., pH was 8.2∼9.8., and decreased according to dissolution time. This is caused by ionic changing with cation and H* ion.

신규 3작용성 메타크릴레이트의 치과용 광중합형 콤포짓트 레진용 단량체로서의 응용 연구

김중곤,정찬문,김민성,김광만,김경남 大韓齒科器材學會 2001 대한치과재료학회지 Vol.28 No.4

Tris[4-(2-hydroxy-3-methacryloxypropoxy)phenyl]methane(THMPM) was prepared easily from triphenylolmethane triglycidyl ether in good yield. As compared with composite resin formulated with difunctional bis-GMA, the physical properties of a newly developed composite resin formulated with trifunctional THMPM was evaluated. Cytotoxicity and acute toxicity of composite resin based on trifunctional THMPM evaluated according to ISO standard method. The depth of cure of the composite resin based THMPM was higher than that of the bis-GMA composite. There were no significant differences in flexural strength and water sorption between the composites resin based on THMPM and bis-GMA. The water-solubility value for the light-activated composite resins formulated with THMPM was much lower than that for a control bis-GMA composite. According to cytotoxicity evaluation, the composite resin based on THMPM showed very mild cytotoxicity with the response index of between 0/0 and 1/0. No acute toxicity of composite resin formulated with trifunctional THMPM was also observed. It is believed that THMPM is promising candidate for application as a photocurable dental composite resin.

종설(綜說) : 한의학 학술지에 발표된 탈모에 관한 연구현황 분석

김광중 ( Kwang Joong Kim ),백승엽 ( Seung Yeob Baek ),임채광 ( Chae Kwang Im ) 대구한의대학교 제한동의학술원 2012 東西醫學 Vol.37 No.4

We performed a systemic analysis of the research situations on hair and alopecia published in the journal of oriental medicine to understand the search trend in the area of hair and alopecia, prepare the basis for the interests and basis on hair and alopecia in the oriental medicine area and above that, to support for the applications in the clinics through this and came to the following conclusions. 1. There are total 95 publications in the domestic journals of oriental medicine area from 1986 to 2011. 2. Total 95 articles were published in 23 journals. “Dong-eui journal of physiology and pathology” had the largest number of articles which was 22(23%) followed by “Oriental journal of ophthalmology, otolaryngology, and dermatology” of 19(20%). 3. The authors who published the largest number of articles as the first author were “Cheon-jong Kim”, “Hyeon-taek Shin”, and “Tae-hu Lee” who published 3 each, and the correspondent author who published the largest number of articles was “Chang-hyeon Lee” who published 8 articles. 4. For the contents and methodologies of the study, there were 16 literature reviews, 36 clinical trials, and 43 animal and other experimental studies and 3 literature reviews were published in 2002, 6 animal and other experimental studies were published in 2006, and 6 clinical trials were published in 2004, 2006, 2009, and 2010 each the most. Based on this study, we hope not only scientific treatises but also these for the oriental medicines and alopecia study related to the oriental medicines to be continued.

복강경하 대장절제술을 시행 받는 환자에서 라모세트론과 온단세트론외 술 후 오심 및 구토 예방 효과 비교

김효중;어전영;어근무;어정한;엄세훈;조광래;김명훈 인제대학교 2011 仁濟醫學 Vol.32 No.-

Objectives : We evaluated the efficacy of ramosetron and ondansetron for preventing postoperative nausea and vomiting (PONV) in laparoscopic colectomy. Methods and Materials : Eighty patients who received laparoscopic colectomy were randomly divided into two groups: R group (ramosetron 0.1mg PO) and O group (ondansetron 4mg twice IV). Injection or oral medication was administered before the induction of anesthesia in each group. Injection was administered at the end of surgery in O group. General anesthesia was induced using propofol and rocuronium, and maintained with sevoflurane, remifentanil and air (FiO2 0.5), We investigated the incidences of PONV in each group by the Rhodes index of nausea, vomiting and retching (RINVR) at postoperative 6 and 24 hours. Results : The incidence of PONV was not different between group at each time points after surgery (at postoperative 6 hours: 20% in group R, 17.5% in group 0, at postoperative 24 hours; 12.5% in group R, 7.5% in group 0). There was no difference in the severity of PONV, satisfaction, rescue drug usage. Conclusion : Prophylactic therapy with ramosetron is as effective as conventional prophylactic therapy with ondansetron for preventing PONV in general anesthesia for laparoscopic colectomy.

교정환자의 브라켓과 치아 경계부에 존재하는 치면세균막내 mutans streptococci 종 및 생물형의 식별

김미애,유소영,김화숙,국중기,임성훈,윤영주,김광원 대한치과교정학회 2005 대한치과교정학회지 Vol.35 No.1

본 연구는 교정환자의 브라켓과 치아 경계부 및 브라켓으로부터 2 mm 이상 떨어진 치아 평활면의 치면세근막에 존재하는 mutaus streptococci의 종 및 생물형에 차이가 있는지를 알아보고자 시행되었다. 조선대학교 치과병원에 내원한 13세 이상 35세 미만의 환자 28명으로부터 브라켓을 장착하고 있는 61개 치아에서 치균세균막을 채취하여 mutans streptococci를 MSB 배지에서 선택적으로 분리한 다음, 이들의 지놈 DNA를 추출하여 dextranase 유전자를 표적으로 하는 중합효소연쇄반응법을 시행하고, 그 증폭물을 Hae Ⅲ로 소화하고, 이를 전기영동하여 제한효소절편길이에 따라 그 종을 식별하였다. 또한 생물형을 조사하기 위하여 생화학적 검사를 실시하였다. 그 결과 브라켓과 치아 경계부 및 브라켓으로부터 2 mm 이상 떨어진 평활면의 치면세균막에 존재하는 mutans streptococci 종은 서로 비슷한 검출 빈도를 보이나 두 곳에 존재하는 mutans streptococci 생물형은 서로 차이가 있는 것으로 나타났다. 향후 브라켓과 치아 경계부 및 치아 평활면의 치면세균막의 mutans streptococci 생물형의 차이와 브라켓 주위의 법랑질 탈회 및 치아우식증 발병과의 상관관계에 대한 연구가 필요하다. The aim of this study was to compare the species and biotypes of mutans streptococci isolated from dental plaques sampled from the interfaces between the bracket and tooth surface and smooth tooth surfaces in orthodontic patients. Dental plaque was collected from the interfaces between brackets and teeth (test group), and from smooth tooth surfaces distant from brackets by more than 2 mm (control group). The dental plaque collected by a sterilized curette was transferred into a vial of 1 X PBS. The sample in the vial was vigorously vortexed for1 min and plated on mitissalivarius bacitracin (MSB) agar plate using cotton tips. The agar plates were incubated at 37℃ in a candle jar for 2 days, and again incubated for 1 more day at anambient temperature. Individual colonies were cultured in TH broth at 37℃ CO₂ incubator. The PCR-RFLP based on dextranase gene was performed for the identification of mutans streptococci at the species-level. For biotyping of mutans streptococci, biochemical tests were performed. There was no significant difference of the species of mutans streptococci isolated from both test and control groups. However, the biotypes of the mutans streptococci isolated from test and control groups were different. These results may offer the basic data to verify the relationship between the mutans streptococci biotype and enamel decalcification or dental caries in orthodontic patients with fixed appliances.

국내 도시 쓰레기의 열분해 특성에 관한 연구

김진호,정영헌,조기철,이협희,오광중 부산대학교 환경문제연구소 1998 環境硏究報 Vol.16 No.-

Pyrolysis system will plat a big role on the resource recovery of wastes without secondary pollution problems comparing usual incineration system. Pyrolysis experiments of municipal solid wastes was conducted and the results are as follows. 1) From tile compression test before the pyrolysis, moisture removal was observed from 70% compression and the variation of the removed moisture amount was detected until 80% compression. Over the 80% compression, there was no change. 2) Non-isothermal pyrolysis reaction constant was found out through the experiment. When the increasing rate of temperature varied from 20 to 40 K/min, the activation energy of cellulose and plastic were 100~160 KJ/mol and 192~239KJ/mo1, respectively. The order of reaction was on the range of 1.2~1.8. As the increasing rate of temperature increased, the activation energy was decreased.

韓末 愛國啓蒙運動期의 實業敎育論 : 新聞論說을 中心으로

金光重 又石大學校 人文科學硏究所 1996 人文論叢 Vol.3 No.-

안면부 기저상피세포암의 인접표피에서 p53 발현 양상에 관한 연구

김광진,김대중,김재훈 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.1

The tumor suppressor gene, p53, has proved to be one of the genes most often modified in human cancers. These aterations consist mainly of point mutations located in the evolutionarily conserved sequences which render the protein inactive for its normal biologic functions. Many mutations of p53 result in a protein product that is abnormally stable, so it becomes readily detectable by immunochemistry. Immunohistochemical overexpression of p53 has been observed not only invasive tumors but also in precancerous or early lesions of tumors of the skin. Overexpression of p53 might be useful marker to identify precursor lesions of cancers arising de novo, which are histopathologically indistinguishable from normal cell. We were studied the p53 expressions immunohistochemically to identify a precursor lesion of basal cell carcinoma in the epidermis adjacent to basal cell carcinoma. With anti-p53 antibodies of DO7, p53 expression was frequently detected in the epidermis adjacent to basal cell carcinomas arising on the face and in the normal epidermis with usual sun exposure. In the epidermis adjacent to basal cell carcinoma, stained cells were occasionally clustered in a small area, but no cluster was found in the normal epidermis with usual sun exposure. The expression was less frequent in the normal epidermis with rare sun exposure. We have carried our PCR-sequencing of exon 5-8 of the p53 gene in 7 basal cell carcinoma and two normal epidermis with immunohistochemically positive and cluster formed. Heterozygous mutations were detected in 4 of 7 (57%) samples investigated. All mutations were G:C-A:T transitions, three at codon 248 and one at codon 273. But no mutation was detected in two normal epidermis with cluster formed positive staining. We conclude that 1. Because all basal cell carcinoma specimens examined here were obtained from facial lesions that were usually exposed to sunlight, the frequent p53 overexpression-detected in the epidermis adjacent to basal cell carcinoma might be related to chronic UV light exposure. 2. The accumulation of p53 was also frequently detected in the epidermis adjacent to basal cell carcinoma developing on the face that was usually sun-exposed. In the epidermis adjacent to basal cell carcinoma, unlike normal epidermis with usual sun exposure that was scattered pattern, the stained cells were occasionally clustered in small areas of the epidermis. 3. A missense mutation was not found in the epidermis adjacent to basal cell carcinoma. 4. The correlation between immunohistochemicl overexpression or pattern and underlying mutation is not absolute, but there might be useful as excisional marker because the p53 staining positive cells ,that was clustered pattern, were possible result for clonal expansion of p53 mutant cells.

수용성 치자색소의 염색성에 관한 연구

김광수,김연중 건국대학교 1997 學術誌 Vol.41 No.2

Te elucidate the dyeability of crocin for silk, cotton and nylon, we investgated variation of K /S according to dyeing time, pH of dyebath and addition of sodium L-ascobate as an antioxidant. The color of crocin on the dyed textile materials depending on the additional method of metallic salt and a kind of metllic salt evaluated by means of CIE L*a*b* system. The wet fastness of dyed fabric increased to add metallic salt, was affected the pre-flexed method or post-fixed method. Generally speaking post-flexed method was higher wet fastness than that of pre-fluted method. Key Words: Natural dyes, Gardnia Jasminoid, Crocin