초등학교 6학년에서 수질환경 교육을 위한 STS 수업 모형의 적용효과

김혜순,최준섭 韓國實科敎育硏究學會 2001 實科敎育硏究 Vol.7 No.1

The purpose of this study is to present a prospective teaching-learning method for environmental education of water quality, and to identify the effects of the STS instruction methods. Two 6th grade classes in D elementary school in Anyang City, Kyunggi district were chosen as an experimental group and a control group, respectively. The experiment was carried out for 2 months by teaching the control group water conservation in the elementary curriculum by traditional teaching-learning methods, and the experimental group by the STS instruction method. The main results of this study were become as follows: (1) When comparing the statistics between the STS and traditional method, the significant level p was 0.173, there is no significant difference under significant level of 0.01. And thus STS method was not much more effective with teaching knowledge related to water pollution(p was less than 0.05). (2) By using the STS teaching method, t became 2.288 and p became 0.025, there was a considerable significant difference under the significant level of 0.01. Application for STS teaching-learning model showed more effective on attitude for environment-conservation than the traditional method(p was less than 0.05).

초등학교 3·4학년의 진로 인식에 관한 연구 : 경기도 지역을 중심으로 Focused on Kyung-gi Province

김자성,최준섭 한국실과교육연구학회 2001 實科敎育硏究 Vol.7 No.2

The purpose of this study is to provide necessary data and information to career education by analyzing the future career cognition level of elementary school students in Kyong-gi province district. The students to the number of 437 of the 3rd and 4th grade students of elementary schools in Kyong-gi province were served as subjects for this study. They were selected by random stratified sampling from their living area. The results of this study were as follows: (1)Many students took pride of doing, and their own aims, original characters or talents. And also they had a tendency to take cognizance of their own original characters or talents as bettor as high economic status. (2)A number more than half students preferred professionals. Most students are interested in computer or playing in the air, and there are different tendencies according to gender. (3)The period of career cognition became earlier and earlier when they themselves first thought about their future career appeared to be the 1st grade and 2nd grade(43.7%). (4)The motives for career selection were ① mass-communication(39.6%) and ②parents ㆍ family ㆍ relatives(32.7%). But very few students(2.7%) wanted to take counsel with their teachers about their career problems.

중추성 요붕증이 동반된 랑게르한스 세포 조직구증 1예

김진호,문준성,문선중,이지은,최재원,은미정,천경아,조인호,윤지성,원규장,이경희 신덕섭,이형우 영남대학교 의과대학 2005 Yeungnam University Journal of Medicine Vol.22 No.2

Central diabetes insipidus (DI) is a syndrome characterized by thirst, polydipsia and polyuria. Langerhans cell histiocytosis is one of the etiologies of DI. Recently we experienced a central DI associated with Langerhans cell histiocytosis. The 44 years old female patient complained right hip pain polydipsia and polyuria. We carried out water deprivation test. After vasopressin injection, urine osmotic pressure was increased form 109mOsmol/Kg to 327mOsmol/Kg (300%). Brain MRI showed a thickened pituitary stalk and at hot bone CT.CT guided biopsy revealed abnormal histiocytes proliferation and abundant lymphocytes, The final diagnosis was central DI associated with systemic Langerhans cell histiocytosis invading hip bone, L-spine and pituitary stalk. Desmopressin and etoposide chemotherapy were performed to the patient.

슬링(sling)과 고정된 지지면에서의 팔굽혀펴기 동작 시 근 활성도 비교

오재섭,박준상,김선엽,권오윤 한국전문물리치료학회 2003 한국전문물리치료학회지 Vol.10 No.3

X-선 회절법에 의한 소결광내의 칼슘페라이트 생성에 미치는 Al_2O_3, SiO_2 및 MgO의 영향

朴埈賢,趙兪貞,尹晟燮,許完旭,金亨順 대한금속재료학회 2002 대한금속·재료학회지 Vol.40 No.7

In order to elucidate the fundamental aspects of the minerals formation processes during sintering, the Fe_2O_3-CaO-Al_2O_3-SiO_2 system and the effect of MgO on synthesized iron ore sinter were studied by image analysis and X-ray diffraction method. Most existed calcium ferrite was identified to be a solid solution of CaO·2Fe_2O_3 with a small amount of solubility of Al_2O_3 and SiO_2. With an increase of the content of Al_2O_3 in the system, the amount of calcium ferrite was increased. On the other hand, the amount of calcium ferrite was decreased, and the amount of hematite was increased with increasing the content of SiO_2. Crystal structure of calcium ferrite with Al_2O_3 and SiO_2 was changed from monoclinic to triclinic as well as the unit cell volume shrank with fixing Al_2O_3 and increasing SiO_2. With increasing the content of MgO(1∼3 wt%), the amount of magnetite was increased and hematite was decreased but calcium ferrite was not changed.

초등학교에서 에너지의 합리적 사용을 위한 STS 프로그램의 개발과 적용 효과

최상길,김채복,최준섭 韓國實科敎育硏究學會 2002 實科敎育硏究 Vol.8 No.1

The purpose of this study was to develop STS teaching-learning program which focuses on real-life experiences for reasonable energy usage, and to verify how STS teaching-learning program affects the understanding knowledge concerned energy and the attitude towards saving energy. The subjects of this study were students of the 6th grade at an elementary school in Kyong-Ju. They were divided into two groups, an experimental group and a control roup. The developed STS teaching-learning program had been applied to the experimental group. However, the traditional teaching-learning process had been employed to the control group for four weeks. The main results of this study are as follows : (1) The developed STS teaching-learning program consists of following subjects ; energy resources, growing energy consumption, heat-energy transfer, energy and environment, saving energy, efficient usage of electricity and opening ‘ANABADA’ market. (2) In the understanding of knowledge concerned energy, there was no difference between the experimental group and control group. (3) In the attitude toward saving energy, there was a considerable significant difference between he experimental group and control group. However, there was no difference between male and female students, respectively.

말기신부전 환자의 혈색소 순환 : 투석 방식에 따른 양상 비교 및 관련 인자들에 대한 고찰

최재혁,김준섭,원기범,박준형,탁우택,이정호 동국대학교 의학연구소 2009 東國醫學 Vol.15 No.2

혈색소 순환은 말기신부전 환자에서 인체 재조합 적혈구 조혈 인자를 투여하여 빈혈을 치료하는 동안 빈번히 관찰되며 이는 환자의 입원과 사망률과 관계가 있다고 알려져 있다. 이에 저자는 투석중인 말기 신부전 환자를 대상으로 혈색소 순환 양상과 이와 연관된 인자들을 알아보고자 하였다. 혈색소 순환의 관련 인자들을 알아보기 위하여 투석 치료를 받고 있는 환자 40명 (혈액투석 환자군: 20형, 복막투석 환자군: 20명)을 대상으로 투석 시작부터 1년 동안의 환자의 나이와 성별, 투석시작 1년간의 평균 Hb, 수혈 횟수, 총입원 횟수, 감염으로 인한 입원 횟수, 혈청 ferritin 농도, 혈청 transferrin saturation (TSAT), 철분제제 복용 유무, 일주일 동안 투여된 rHuEPO 양, rHuEPO의 변화량, 알부민, C-reactive protein (CRP) 및 입원 원인 등을 후향적으로 조사하였다. 전체 환자 40명 중 33명 (82.5%)에서 혈색소 순환이 관찰되었다. 혈액투석 환자군에 비해 복막투석 환자군에서 혈색소 순환 첫수가 유의하게 높았다 (p=0.037).혈색소 순환 발생군과 혈색소 순환 미발생군의 관련인자들을 비교하였을 경우 혈색소 순환 발생군에서 총 입원 첫수 (p=0.01), 감염으로 인한 입원 횟수 (p=0.036)가 유의하게 많았으며, 혈중 알부민 수치는 유의하게 낮았다 (p=0.003).그러나 두 군간의 나이, 성별, 수혈 횟수, 혈청 ferritin농도, 혈청 transferrin saturation (TSAT) 및 혈청 철분 농도는 유의한 차이가 없었다. 혈색소 순환의 빈도는 일주일 동안 투여된 r-HuEPO변화량과 양의 상관관계를 보였고 (p=0.003),혈중 알부민 수치와 음의 상관관계를 보였다 (p=0.013). 복막투석 환자군에서 혈액투석 환자군에 비해 혈색소 순환이 유의하게 높게 발생하였다. 일주일 동안 투여된 r-HuEPO 변화량, 입원 및 혈청 알부민 수치는 투석 시작부터 1년 동안의 혈색소 순환과 관련이 있었다. Hemoglobin cycling is frequently observed during treatment of anemia with recombinant human erythropoietin (r-HuEPO) in patients with end stage renal disease (ESRD) it is also reported to be associated with hospitalization and morbidity. We analyzed hemoglobin cycling and potential associated factors in patients on dialysis. Forty new dialysis patients (20 hemodialysis, HD and 20 peritoneal dialysis, PD) were recruited during their first year. Age, gender, mean hemoglobin level, frequency of transfusion, frequency of hospital admission, frequency of admission due to infection, serum ferritin, transferrine saturation, iron levels, rHuEPO dose per week, serum albumin, and c-reactive protein were retrospectively evaluated in order to examine the possible correlations with hemoglobin cycling. Thirty-three patients (82.5%) were identified in the hemoglobin cycling group. The PD group had a higher frequency of hemoglobin cycling than did the HD group (p=0.037). The hemoglobin cycling group showed a significantly higher frequency of hospital admission (P=0.001), admission due to infection (p=0.036) and a lower serum albumin level (p=0.003) than the other group, but there was no significant difference between the groups for age, gender, frequency of transfusion, serum ferritin, transferrine saturation, and iron levels. The frequency of hemoglobin cycling showed a positive correlation with the i-HuEPO dose variation per week (p=0.003) and a negative correlation with serum albumin level (p=0.013). The PD group had a higher frequency of hemoglobin cycling than the HD group, and the change of rHuEPO dose per week, hospitalization and serum albumin were associated with the hemoglobin cycling during the first year of dialysis.

Development of the solar tracking technology of floating photovoltaic plant using ballasting system

Kim Jun-Ho(김준호),Kim Seung-seop(김승섭),Lee Gil-Song(이길송),Yang Yeon-Won(양연원),Jeong Seon-Ok(정선옥),Lew Jae-Moon(류재문),Kim Hyo-chul(김효철),Oh Jung-keun(오정근) 한국태양에너지학회 2014 한국태양에너지학회 학술대회논문집 Vol.2014 No.11

Antagonistic regulation of PAF1C and p-TEFb is required for oligodendrocyte differentiation.

Kim, Suhyun,Kim, Jun-Dae,Chung, Ah-Young,Kim, Hyung-Seok,Kim, Young-Seop,Kim, Myoung-Jin,Koun, Soonil,Lee, You Mie,Rhee, Myungchull,Park, Hae-Chul,Huh, Tae-Lin The Society 2012 The Journal of neuroscience Vol.32 No.24

<P>Oligodendrocytes are myelinating glial cells in the CNS and are essential for proper neuronal function. During development, oligodendrocyte progenitor cells (OPCs) are specified from the motor neuron precursor domain of the ventral spinal cord and differentiate into myelinating oligodendrocytes after migration to the white matter of the neural tube. Cell cycle control of OPCs influences the balance between immature OPCs and myelinating oligodendrocytes, but the precise mechanism regulating the differentiation of OPCs into myelinating oligodendrocytes is unclear. To understand the mechanisms underlying oligodendrocyte differentiation, an N-ethyl-N-nitrosourea-based mutagenesis screen was performed and a zebrafish leo1 mutant, dalmuri (dal(knu6)) was identified in the current study. Leo1 is a component of the evolutionarily conserved RNA polymerase II-associated factor 1 complex (PAF1C), which is a positive regulator of transcription elongation. The dal(knu6) mutant embryos specified motor neurons and OPCs normally, and at the appropriate time, but OPCs subsequently failed to differentiate into myelinating oligodendrocytes and were eliminated by apoptosis. A loss-of-function study of cdc73, another member of PAF1C, showed the same phenotype in the CNS, indicating that PAF1C function is required for oligodendrocyte differentiation. Interestingly, inhibition of positive transcription elongation factor b (p-TEFb), rescued downregulated gene expression and impaired oligodendrocyte differentiation in the dal(knu6) mutant and Cdc73-deficient embryos. Together, these results indicate that antagonistic regulation of gene expression by PAF1C and p-TEFb plays a crucial role in oligodendrocyte development in the CNS.</P>

Primary amelanotic melanoma of the mandibular gingiva

Kim, Byeong Jun,Kim, Hyeong Seop,Chang, Yong Joon,Kwon, Kee Hwan,Cho, Seong Jin Korean Cleft Palate-Craniofacial Association 2020 Archives of Craniofacial Surgery Vol.21 No.2

Oral mucosal melanoma is a very rare type of malignant melanoma, the characteristics of which differ from those of cutaneous melanoma. Primary amelanotic melanoma of the mandibular gingiva, which can invade the mandibular bone, is very rare worldwide. Here, we report a case in which we performed a reconstruction of the mandible and gingiva using the fibula osteocutaneous free flap procedure to treat a patient diagnosed with a primary amelanotic melanoma of the mandibular gingiva. The procedure was successful, and no recurrence was observed 10 months after surgery. Oral mucosal melanoma has a much poorer prognosis and a lower 5-year survival rate than cutaneous melanoma. However, recently, immunomodulatory therapies for mutations in melanocytic lesions have been used effectively to treat the increasing number of patients developing this type of melanoma, thus improving the prognosis of patients with oral mucosal melanoma.