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Role of PET/CT Scan and Brain MRI in Patients with Ground-glass Opacity Lung Nodules
( Jun Whi Song ),( Jae Uk Song ),( Kyung Jong Lee ),( Kyeong Man Jeon ),( Won Jung Koh ),( Gee Young Suh ),( Man Pyo Chung ),( Ho Joong Kim ),( O Jeong Kwon ),( Sang Won Um ) 대한결핵 및 호흡기학회 2011 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.112 No.-
A Case of Pleural Paragonimiasis Confused with Tuberculous Pleurisy
( Jun Whi Song ),( Goo Hyeon Hong ),( Jae Uk Song ),( Woo Youl Kim ),( Seo Goo Han ),( You Sang Ko ),( Bok Soon Chang ),( Byeong Ho Jeong ),( Jung Seop Eom ),( Ji Hyun Lee ),( Byung Woo Jhun ),( Kyeon 대한결핵 및 호흡기학회 2014 Tuberculosis and Respiratory Diseases Vol.76 No.4
Here, we report a case of pleural paragonimiasis that was confused with tuberculous pleurisy. A 38-year-old man complained of a mild febrile sensation and pleuritic chest pain. Radiologic findings showed right pleural effusion with pleural thickening and subpleural consolidation. Adenosine deaminase (ADA) activity in the pleural effusion was elevated (85.3 IU/L), whereas other examinations for tuberculosis were negative. At this time, the patient started empirical anti-tuberculous treatment. Despite 2 months of treatment, the pleural effusion persisted, and video-assisted thoracoscopic surgery was performed. Finally, the patient was diagnosed with pleural paragonimiasis based on the pathologic findings of chronic granulomatous inflammation containing Paragonimus eggs. This case suggested that pleural paragonimiasis should be considered when pleural effusion and elevated ADA levels are observed.
전폐 세척술로 부분 관해 후 GM-CSF 투여로 치료된 특발성 폐포단백증
송준휘 ( Jun Whi Song ),박순효 ( Sun Hyo Park ),강경우 ( Kyung Woo Kang ) 대한결핵 및 호흡기학회 2009 Tuberculosis and Respiratory Diseases Vol.67 No.6
Idiopathic pulmonary alveolar proteinosis (PAP) is a rare disorder characterized by surfactant component accumulation in the alveolar space. Idiopathic PAP has recently been recognized as a autoimmune disease of impaired alveolar macrophage function caused by autoantibodies against granulocyte-macrophage colony-stimulating factor (GM-CSF). While whole lung lavage has been the standard treatment, not every patient shows a complete response. Subcutaneous injection or inhalation of GM-CSF is another promising treatment option for PAP. A 45-year-old patient visited our hospital for dyspnea, he was diagnosed as PAP and underwent whole lung lavage. Eighteen months later, the patient had not achieved complete remission in despite of initial response. After then he was administered with GM-CSF (5 μg/kg/day, subcutaneous injection) for fivetimes a week during 2 months. Nine months later, the abnormal shadows in high-resolution computed tomography (HRCT) decreased and the patient fully recovered in forced vital capacity. After 60 months, the HRCT scan showed complete remission of PAP.
( Bo Ksoon Chang ),( Seo Goo Han ),( Woo Youl Kim ),( You Sang Ko ),( Jun Whi Song ),( Goo Hyeon Hong ),( Jung Seop Eom ),( Ji Hyun Lee ),( Byung Woo Jhun ),( Won Jung Koh ) 대한결핵 및 호흡기학회 2013 Tuberculosis and Respiratory Diseases Vol.75 No.1
Carbohydrate antigen 19-9 (CA 19-9) is a widely-used tumor marker in patients with pancreatic cancer. However, some patients with respiratory disease also exhibit elevated serum CA 19-9 levels. We report a case of normalization of elevated serum CA 19-9 levels after treatment of the nodular bronchiectatic form of Mycobacterium abscessus lung disease. A 40-year-old man visited our hospital because of chronic cough and sputum. A computed tomography scan revealed severe bronchiectasis in the right upper and right middle lobes. Nontuberculous mycobacteria were repeatedly isolated and identified as M. abscessus. The serum CA 19-9 level was elevated to 142.35 U/mL (normal range, <37 U/mL). Surgical resection was performed because of failure of sputum conversion after antibiotic treatment. The serum CA 19-9 level returned to the normal range after surgery. This case suggested that serum CA 19-9 levels could be elevated in patients with the nodular bronchiectatic form of M. abscessus lung disease.
반전된 Takotsubo 형태를 보이는 스트레스성 심근병증 1예
임상우 ( Sang Woo Yim ),천우정 ( Woo Jung Chun ),오주현 ( Ju Hyun Oh ),박용휘 ( Yong Whi Park ),박용환 ( Yong Whan Park ),박건태 ( Geon Tae Park ),송준휘 ( Jun Hwi Song ) 대한내과학회 2009 대한내과학회지 Vol.76 No.6
스트레스성 심근병증은 다양한 육체적 또는 정신적 스트레스 후 발생하는 심장질환 증후군으로 초기 임상양상이 급성 관상동맥 증후군과 유사하지만 양호한 예후를 갖는다. 그러나 기존에 발표된 연구에서는 대부분의 환자에서 심첨부나 중간부 좌심실에서 무운동성을 관찰되었으나 저자들은 심실 기저부의 무운동성이 관찰되는 스트레스성 심근병증증례를 경험하였기에 보고한다. Stress-induced cardiomyopathy, known as Takotsubo cardiomyopathy, is a newly described clinical entity characterized by transient left ventricular apical ballooning and left ventricular apical dyskinesis, with no significant stenosis on the coronary angiogram. We describe a patient who had transient cardiomyopathy with akinesia of the basal portions of the left ventricle and hyperkinesia of the apex. This is the first case of stress-induced cardiomyopathy with an "inverted Takotsubo" contractile pattern triggered by emotional stress in Korea. The cause of stress-induced cardiomyopathy is unclear, but catecholamines probably play a role in this syndrome. This entity could provide clues to the pathophysiology underlying stress-induced cardiomyopathy. (Korean J Med 76:746-751, 2009)