감각자극 분석을 통한 종합병원 다인 병실의 치유 환경에 관한 건축 계획적 연구

정주현,양내원 한국의료복지시설학회 2006 의료·복지 건축 Vol.12 No.2

Patients use the senses all the time, mostly simultaneously. Senses are never turned off even patients in serious condition use some of the senses. Space is the inexhaustible source of stimuli. So far we have thought that it is impossible to come up with a set of rules and guidelines that cover all the possible situations involving senses and when there have been usually no conscious coordination between different sensorial stimuli and the comprehensive perception of space always results from the engagement of combination of senses and other inputs based on knowledge and experience. This study concerns about patients’ demand analysis through senses. The reflection of patients’ demand to the ward planning can develope the healing environment.

알코올 의존과 후보 유전자들간의 연관성 연구

정인원,김헌,홍주봉,지경환,이규영 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.6

연구목적 : 알코올 대사와 중추신경계내의 알코올 작용부위와 관련한 일부 후보유전자들이 알코올 의존과 관련이 있는지를 확인하고자 하였다. 방 법 : DSM-IV로 진단된 알코올 의존 환자 128명과 정상 대조군 128명을 대상으로 후보 유전자들의 다형성을 중합효소 연쇄반응과 제한효소처리법을 이용하여 동정하였다. 여기서 분리된 대립유전자와 유전자형에 따른 빈도의 차이를 유전자별로 각각 비교하였으며, 알코올 의존에 작용하는 서로 다른 유전자들에 의한 영향력을 배제하기 위하여 logistic regression 분석을 적용하였다. 결 과 : 알코올 의존군에서는 ALDH_2 유전자의 NN(wild type)형이 정상대조군에 비하여 유의하게 많았다(chi-square test, p<0.001). logistic regression analysis를 통하여 다른 유전자들에 의한 영향을 보정한 상태에서 ALDH_2가 NN(wild type)인 경우 다른 아형에 비하여 알코올 의존에 대한 odds ratio는 130.312이며 그 신뢰구간은 (17.22, 986.43)이었다. 한편, ASA는 N-glycosylation 부위에 변이형 대립유전자를 갖고 있는 경우(AG or GG)는 wild type에 비하여 알코올 의존에 대한 위험도는 2.344배이며 그 95% 신뢰구간은 (1.128, 4.871)이었다. 결 론 : 알코올 의존과 ALDH_2 유전자간에는 밀접한 연관성이 확인되었다. 또한 다른 유전자들은 개별 연관분석에서 의미있는 연관성이 관찰되지는 않았지만 logistic regression analysis를 통하여 N-glycosylation 부위에 다형성이 있는 ASA 유전자가 알코올 의존과 관련이 있음을 시사하였다. Objectives : This study was to explore the association between alcohol dependence and five candidate genes related to the metabolism of alcohol and the enzymes of the suspected sites in CNS. Methods : The genotype and allele frequencies of five candidate genes in 128 male hospitalized patients who met DSM-IV criteria for alcohol dependence were compared with 128 age-matched healthy male control subjects using polymerase chain reaction and restriction fragment length polymorphism. A logistic regression analysis was applied in order to exclude the reciprocal interactions among five candidate genes. Results : The NN genotype frequency of the ALDH_2 gene was significantly higher in alcoholic patients than in control subjects(chi-square test, p<0.001). No difference in frequency was found in the other four genes. In a logistic regression analysis, the odds ratio for alcohol dependence in the NN genotype of the ALDH_2 gene and AG or GG genotypes of the N glycosylation site on the ASA gene were 130.312(95% confidence interval, 17.22-986.43) and 2.344(95% confidence interval. 1.128-4.871), respectively. Conclusion : The result reiterates the association of the ALDH_2 gene polyporphism and the alcohol dependence. Logistic regression analysis additionally suggested that the N-glycosylation site on the ASA gene was associated with alcohol dependence.

1997學年度 新入生 實態調査

元俊載,朴州信,鄭永壽 인하대학교 학생생활연구소 1998 學生生活硏究 Vol.18 No.-

조류생산잠재력에 의한 진양호의 생물학적 수질평가

주현수,김진,박종천,정원석,이원교,이우범 國立 麗水大學校 環境問題硏究所 2000 環境硏究論文集 Vol.3 No.-

On filtrated and autoclaved water samples from Lake Jinyang, algal growth potential(AGP) test using Selenastrum capricornutum Printz were performed from February, 1999 to October, 1999 in order to assess fertility potential of the lake and to identify possible limiting nutrients. Algal growth potentials of the filtrated and filtrated after autoclaved samples were 0.018 ㎎/ℓ ~9.965 ㎎/ℓ and 0.018 ㎎/ℓ ~28.788㎎/ℓ respectively during surveyed period. AGP of the filtrated after autoclaved were higher than those of the filtrated only except some specific stations. The points of maximum growth were measured after addition of N, P and unenriched samples (control). The limiting factor was nitrogen only at site 5 in spring and phosphate appeared to be the major limiting nutrients in spike test throughout the year, especially during spring and autumn. Accoding to trophic level by Sudo(1980), the water quality of lake Jinyang were estimated mesotrophic at site 2, 4, 5, 6 in spring, at site 3, 6 in summer and at site 6 in autumn but all other sites were oligotrophic. But it is suggested that if we have not manigement of lake Jinyang, the water quality is possible to convert eutrophic.

^152Sm에서의 다중극 혼합비에 관한 연구

정원모,주관식,황한렬,정원균 연세대학교 자연과학연구소 1986 學術論文集 Vol.17 No.-

동일한 선원에 대한 감마-감마, 감마-내부전환전자 각상관관계 실험을 통하여 변형핵인 ^152Sm의 혼합비(δ)와 121.8keV전이의 내부 전환전자 입자매개변수(b_2)를 결정하였다. 감마선을 검출하는데는 두대의 Ge(Li)검출기를 내부전환전자를 검출하는 데는 표면장벽형검출기를 사용하였다. 실험을 통하여 다음과 같은 결과를 구하였다. 244.7 keV-121.8 keV ; δ =-0.012±0.007 688.6 keV-121.8 keV ; δ =17.4±3.01 964.0 keV-121.8 keV ; δ =9.51±1.93 1112.0 keV-121.8 keV ; δ =12.30±2.05 1408.0 keV-121.8 keV ; δ =0.16±0.07 964.0 keVγ-121.8 keVe_K ; b_2=1.66±0.26 1408.0 keVγ-121.8 keVe_K ; b_2=1.63±0.10 1408.0 keVγ-121.8 keVe_L ; b_2=0.99±0.13 혼합비는 PPQ(Pairing-Plus-Quadrupole)모델과 IBA(Interacting-Boson-Approximation)모델로부터 얻은 이론값과 비교하여 보았고 또한 입자매개변수값이 이론값과 큰 차이가 있는 것으로 보아 변형핵의 저에너지 E_2 전이에서 ‘anomaly’가 있는 것으로 추정된다. The mixing ratios (δ) and the internal conversion electron particle parameters (b_2) of the 121.8keV transition in deformed ^152Sm nuclei were determined by comparing the γ-γ and γ-e angular correlation measurements made with the same source. The experimental apparatus was constructed with a surface barrier detecter for electrons and two Ge(Li) detectors for gamma rays. The following results were obtained. 244.7 keV-121.8 keV ; δ =-0.012±0.007 688.6 keV-121.8 keV ; δ =17.4±3.01 964.0 keV-121.8 keV ; δ =9.51±1.93 1112.0 keV-121.8 keV ; δ =12.30±2.05 1408.0 keV-121.8 keV ; δ =0.16±0.07 964.0 keVγ-121.8 keVe_K ; b_2=1.66±0.26 1408.0 keVγ-121.8 keVe_K ; b_2=1.63±0.10 1408.0 keVγ-121.8 keVe_L ; b_2=0.99±0.13 The results are compared with the theoretical values derived from the Pairing-Plus-Quadrupole model and from the Interacting-Boson-Approximation model, and an 'anomaly' was found in the low-lying E_2 transition for deformed ^152Sm nuclei.

증후성 단독 중뇌동맥협착의 예후

이수주,이광호,정진상,조수진,이원용,이한보 대한신경과학회 1999 대한신경과학회지 Vol.17 No.1

154Gd의 감마-감마 각 상관관계 측정

朱寬植,鄭元謨 明知大學校 自然科學硏究所 1984 자연과학논문집 Vol.2 No.-

?Gd의 몇몇 감마전이에 대한 혼합비 δ를 구하기 위하여 감마-감마 각 상관관계 실험을 하였다. 두개의 Single Channel Analyzer 와 세개의 Counter, 그리고 하나의 Univeral Coincidence 를 사용한 동시회로가 본 실험에 사용되었다. 각 상관계수 Akk를 구하기 위하여, 각도 90?, 120?, 150?180?에서 동시계열(1596-123 keV, 1274-123keV,1005-123keV,873-123keV,248-123keV,723-873keV)을 조사하였다. δ(1596)=-0.091?, δ(1274)=-0.0009? δ(1005)= 6.3?, δ(873) =-5.9?, δ(248)= 0.295?를 구하였다. Gama-gamma angular correlation measurements were perormed to determine the mixing ratio δof some γ-transistions in ?Gd. The coincidence circuit with two single channel analyzer, three counters and a universal coincidence were used to this experiment. To get the angular correlation coefficient Akk, the angular correlation function W(Θ) was fitted to the coincidence sequences at the angular positions Θ=90?, 120?150?and 180?. Results for themixing ratios are: δ(1596)=-0.091+0.049-0.052, δ(1274)=-0.009+0.016-0.034, δ(1005)=6.3+4.5-1.8, δ(873)=-5.9+2.5-1.8, δ(248)=0.295+0.070-1.134

이동통신 멀티미디어 데이터서비스의 트래픽 특성 모델링 및 성능분석

정용주,백천현,김후곤,최택진,양원석,황흥석 한국경영과학회 2003 한국경영과학회지 Vol.28 No.2

The aim of this study is to identify the data traffic capacity of 3G mobile communication networks, especially of cdma2000-1X networks. Three-layered ON/OFF traffic model is used to describe the dynamics of data traffics and the process of data transmission such as packet scheduling. We construct a simulator fully incorporating packet handling process of cdma2000-1X data network as well as three-layered ON/OFF traffic model describing the behavior of source data traffics. To get influence of traffic parameters on performance measures, the extensive simulations were performed for several data sets which are obtained from real trace data or previous studies. The experimental results show that the engineered throughput satisfying QoS criteria is approximately 20% of total capacity. Finally, some proposals to improve the system capacity are followed.

BMS 수리모형하에서 시스템의 수리효과 및 고장강도함수의 모수추정

윤원영,정석주,정일한,김종운,정상욱 한국경영과학회 2000 韓國經營科學會誌 Vol.25 No.4

Estimation problems of parameters of the failure process and the repair effect in repairable systems are considered. We propose estimation procedures in repairable systems without preventive maintenances. The fallure process is modeled by a proportional age reduction model (Brown. Mahoney, Sivazlian [5]) which is able to consider both aging and repair effects. Maximum likelihood method is used to estimate the repair effect and parameters of intensity function simultaneously. Simulations are performed to evaluate the accuracy of estimators. A numerical example is also presented.

Retinoic Acid가 흰쥐 태자 혀조직의 분화와 Laminin 합성에 미치는 영향에 대한 연구

김혜주,정호삼,서윤경,백두진,김원규,윤지희,이방헌 대한췌담도연구회 2000 대한췌담도연구회지 Vol.5 No.4