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한오수,안준호,송선희,조맹제,김장규,배재남,조성진,정범수,서동우,함봉진,이동우,박종익,홍진표 대한신경정신의학회 2000 신경정신의학 Vol.39 No.2
연구목적: 정신장애의 정확한 진단과 평가는 임상에서뿐만 아니라 신뢰성 있는 연구를 위해서도 매우 중요하다. Structured Clinical Interview for DSM-IV(SCID)는 임상전문가들이 사용하는 진단도구로서, 비교적 짧은 시간에 정확한 진단을 내릴 수 있다. 본 연구는 한국어판SCID를 개발하고 그 신뢰도를 평가하기 위해 수행되었다. 방법: 국문학자가 포함된 번역위원회를 통하여 연구용판 SCID를 번역한 후, 정신과 의사 2인과 임상심리학자 1인에게 한국어판SCID 실시방법을 교육시킨 뒤 한국어판SCID를 이용한 면담의 평가자간 신뢰도 (interrater reliability)를 검증하였다. 면담 대상은 1999년 2월에서 3월까지 2개 병원 정신과에 치료중인 환자 90명(남:41명, 여:29명)이었다. 결과: 현재 장애(current disorder) 평가에서 주요 우울장애, 기분부전장애, 정신분열병, 알코올 남용 및 의존, 기타 물질 남용 또는 의존, 여러 불안장애들 및 섭식장애 등과 같은 대부분 장애의 kappa값은 .70이상으로 매우 높았다. 그 이외의 양극성 장애, 망상장애, 광장공포증, 감별 불능 신체화 장애 및 건강염려증의 kappa값도 .69에서 .40사이로 수용할 수 있는 정도였다. 평생 장애(lifetime disorder)에서는 양극성 장애(k=.69)와 감별 불능 신체화장애(k=.59)를 제외한 다른 모든 장애의 kappa값이 .70이상이었다. K-SCID 면담시 Ⅰ축 질환에 대하여 흔하게 다중 진단이 내려졌으며, 평균 진단 수는 1.5∼1.7개로 나타났다. 결론: 한국어판 SCID는 신뢰도가 높은 진단도구로 생각되며, 향후 정신질환의 정확한 진단과 임상연구에 유용하게 사용될 수 있다. Objectives: Accurate diagnosis and assessment for psychiatric disorders is crucial for research, as well as for clinical practice. Structured Clinical Interview for DSM-Ⅳ(SCID-RV) is a less time-consumimg and more accurate structured diagnostic interview form. It can be used by clinical professions and is known for a reliable diagnostic tool. Present study was conducted to develop Korean version of SCID-RV and to test the inter-rater reliability. Methods: The authors have translated original SCID-RV into Korean, and revised in parallel with sociocultural background of Korea. Ninety patients from two psychiatric hospitals, both outpatient and inpatient, were interviewed and rated independently by three raters. Results: The kappa coefficients for most of illnesses, such as major depressive disorder, dysthymia, schizophrenia, alcohol abuse and dependency, anxiety disorder and eating disorder were excellent(>0.70) in the evaluation of current disorders. And the kappa coefficients for bipolar disorder, delusional disorder, agoraphobia, undifferentiated somatoform disorder, and hypochondriasis were acceptable(>0.40) in the evaluation of current disorders. In the evalua-tion of lifetime disorders, the concordant rates of all the diagnoses except bipolar disorder and undifferentiated somatoform disorder were excellent. Lack of hierarchy in DSM-Ⅳ allows for multiple Axis I diagnoses. Mean numbers of Axis I diagnoses per subject assigned by the three raters were 1.5-1.7. Conclusions: Our findings confirm that SCID-RV yields highly reliable diagnoses. SCID-RV is recommended for accurate diagnosis in clinical practice and research on psychiatric disorders.
정신분열병환자의 혈장 Homovanillic Acid와 3-Methoxy-4-Hydroxy-Phenylglycol 농도비와 임상적 변수와의 관계
김종훈,이인상,한규희 대한생물치료정신의학회 2000 생물치료정신의학 Vol.6 No.2
The homovanillic acid(HVA) and 3-methoxy-4-hydroxyphenylglycol(MHPG) , the metabolites of dopamine and norepinephrine, in plasma were measured to examine the monoaminergic contribution to the psychopathology of schizophrenic illness. The relationship between HVA/MHPG ratio and clinical variables, such as positive-negative subgroup, age, onset age, duration of illnesstreatment and presence of family history. Twenty-five patients with schizophrenia after washout of neuroleptics were recruited for this study. The mean value of HVA/MHPG ratio was 2.15 in total patients with schizophrenia. Subjects were divided to two groups as high and low ratio group. No statistical differences were found between the high and low raio group in areas of clinical variables. However there appeared bimodal distribution in histogram. One group(n=21) showed the approximate normal distribution, another small group(n=4) distributed discretely beyond the ratio value 3. All of the patients of small group were positive schizophrenia. This finding suggests the possibility of clustering the schizophrenic illness biologically. In the near future the authors will try to confirm this finding in expanded numbers of subjects and in conjunction with 5-HIAA, another interesting monoaminergic metabolite.
Identification of the Brown Planthopper (Nilaparvata Lugens)Resistance Candidate Genes in Rice
Jong Seong Jeon,Min Young Song,Dong Soo Park,Soo Kwon Park,Sang Kyu Lee,Hyun Bi Kim,Jong Hee Lee,Tae Ryong Hahn,Gi Hwan Yi,Min Hee Nam 한국응용생명화학회 2008 Applied Biological Chemistry (Appl Biol Chem) Vol.51 No.5
Leasing versus selling : marketing strategy choice in durable goods oligopolies
Jong-Hee Hahn,Sang-Hyun Kim 한국계량경제학회 2007 JOURNAL OF ECONOMIC THEORY AND ECONOMETRICS Vol.18 No.4
This paper examines firms’ strategic choice between leasing and selling in a market for horizontally differentiated durable goods. We show that firms’ decisions on marketing strategy may lead to socially inefficient outcomes: firms choose leasing even though direct sales are socially more desirable. Moreover, a prisoners’ dilemma situation may arise: firms choose leasing while they could be better off by selling together. We also discuss on the impact of the advance of information infrastructure on the marketing practice in software markets.
Price Discrimination with Loss Averse and Horizontally Differentiated Consumers
( Jong-hee Hahn ),( Jinwoo Kim ),( Sang-hyun Kim ),( Jihong Lee ) 한국경제학회 2018 The Korean Economic Review Vol.34 No.2
This paper considers a monopolist seller facing horizontally differentiated consumers, whose preferences are reference-dependent and loss averse in the frame of Koszegi and Rabin (2006). Our results on optimal menu suggest that consumer loss aversion does not necessarily limit the benefits of screening under the horizontal demand structure, in contrast to the findings of Hahn, Kim, Kim and Lee (2018) and Herweg and Mierendorff (2013) who consider the case of vertically differentiated preferences.