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이지영,이승우,김용구,정인식,설일환 慶熙大學校 1997 論文集 Vol.26 No.-
Experiments were conducted to find out the optimum cultural conditions for micro-cross sectioned leaf segments of Gypsuphila paniculata L. Gerbera hybrida and Dianthus caryophyllus. Survival percentages of micro-cross sectioned segments were the highest in gypsophila, followed by carnation. Gerbera showed on survived segments. In gypsophila, segments thicker than 400㎛ were required to obtain over 75% survival. The percentage of adventitious bud formation was much higher with 600㎛ segment as compared with 400㎛. The regeneration of micro-cross sectioned segments of gypsophila was not sensitively affected by the auxins at varying concentrations. The elongation of adventitious shoot was promoted by kinetin compared with BA. In segments of 600㎛ thickness, adventitious shoot formation was promoted by BA compared with kinetin Adventitious shoot formation or shoot growth was not affected by KNO_3 concentrations with the segments of 400㎛ thickness. But adventitious shoot elongation was promoted significantly with segments in 600㎛ thickness. KH_2PO_4 (170 mg/1, standard concentration of MS medium) was effective for adventitious shoot formation. MgSO_4 also promoted adventitious shoot formation myo-Inositol tended to be suppressed regeneration of gypsophila.
( Jee Whan Kim ),( Young Shin Chung ),( Jung-yun Lee ),( Eun Ji Nahm ),( Sunghoon Kim ),( Sang Wun Kim ),( Young Tae Kim ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-
Objective: To define the impact of administration of Bupivacaine (100mg/20ml) at incisional site in postoperative pain after Laparo-Endoscopic Single (LESS) adnexal surgery. Methods: This was a prospective study of periumbilical infiltration of Bupivacaine at incisional site in LESS Adnexal Surgery. Study was performed at Yonsei Cancer Center during February 2017 to March 2018. The study group was randomly selected preoperatively and divided into two groups to receive either bupivacaine or no analgesic medicine at incision site. Total 111 patients participated in bupivacaine group, and 110 patients were in control group. Bupivacaine group received 1 vial (100mg/20mL) of bupivacaine administered at periumbilical surgical site. While control group did not receive any medicine during the closure of incisional site. Postoperative pain assessment was performed by using Numerical Rating Scale (NRS) system after 6 hours, 24 hours, 48 hours from the end of surgery. Two groups were compared for age, body mass index, and number of previous abdominal surgeries. Both groups received intravenous, oral analgesia for controlling abrupt postoperative pain. Results: Bupivacaine group had significantly lower postoperative pain scores after 6 hours (2.7±0.7 vs 3.4±1.2, P= 0.0001) and after 24 hours (2.3±0.7 vs 2.8±1.0, P=0.0001) from operation. There was no difference in pain score after 48 hours from surgery (2.0±0.7 vs 2.1±0.8, P= 0.135). Bupivacaine group used significantly less PCA (9 (8.1%) vs 73(66.4%)) and used less number of analgesia after operation (3.2+0.9 vs 3.8+1.1, P= 0.0001). There was no difference in hospital stay in two groups. Conclusion: Periumbilical infiltration of Bupivacaine at incision site was useful in reducing postoperative pain scores after 6hours and 24 hours after operation. Also, bupivacaine injection reduced frequency of postoperative analgesic use. Bupivacaine injection could be an option to improve postoperative pain and faster recovery after LESS adnexal surgery.
Kim, Sung-Han,Yeo, Sang-Gu,Cho, Jae-Hyun,Bang, Ji-Whan,Kim, Hong-Bin,Kim, Nam-Joong,Jee, Youngmee,Cho, Haewol,Oh, Myoung-don,Choe, Kang-Won 대한감염학회 2007 감염과 화학요법 Vol.39 No.2
목적 : 두창백신 접종 후 일반적으로 접종 부위에 거즈를 먼저 덮고, 그 위에 반투과막을 덮어주는 드레싱을 권장하고 있다. 저자들은 이러한 드레싱 방법의 효율성을 알아보기 위해서 두창백신 접종 후 접종 부위, 거즈 바깥부위, 반투과막 바깥 부위에서 각각 분비되는 바이러스양을 정량적으로 비교하였다. 재료 및 방법 : Lancy-Vaxina^((R)) (Berna Biotech, Swiss) 두창백신 1:10 희석연구에 참여한 자원자들 중에서 접종부위에 정해진 기간에 검체 채취에 동의한 40명을 대상으로 연구를 진행하였다. 참가자들은 두창백신 접종 후 6, 8, 10, 13, 15일에 각각 방문하여 드레싱을 교체하였다. 드레싱을 교체하면서 두창백신 접종 부위, 거즈 바깥부위, 반투과막 바깥부위에 면봉을 이용해서 각각 검체를 채취하였다. 검체는 냉동 보관한 후 plaque assay를 통하여 정량적으로 바이러스 역가를 측정하였다. 결과 : 총 40명의 자원자가 본 연구에 참가하였다. 백신 접종 부위에서 채취한 156 검체 중 126건(81%)에서 백시니아바이러스가 검출되었다. 백신 접종 부위에서 접종 8일째 바이러스 역가의 평균(geometric mean titer(log_(10))은 3.91 pfu/mL이었다. 거즈 바깥부위에서 총 39검체가 얻어졌고, 이 중 16건(41%)에서 백시니아바이러스가 검출되었다. 거즈 바깥부위에서 접종 8일째 바이러스 역가의 평균은 0.91 pfu/mL이었다. 반투과막 바깥부위에서 총 133 검체가 얻어졌고, 이 중 1건(0.8%)에서 백시니아바이러스가 검출되었다. 접종 8일째 거즈 바깥부위에서는 바이러스가 검출되지 않았다. 결론 : 두창백신 접종 후에 거즈를 덮고 그 위에 반투과막을 덮어주는 드레싱 방법은 백시니아바이러스 배출을 효과적으로 줄여줄 수 있음을 확인하였다. Background : We compared vaccinia virus shedding from the vaccine inoculation site (vaccination lesion) and two sites of a dressing covering the vaccination site; the outer surface of the semipermeable dressing (outer surface) and the inner surface of the semipermeable dressing, that is, the surface of a folded gauze under the semipermeable membrane (gauze surface) Material and Methods : Subjects were recruited from the volunteers who participated in a clinical trial of the efficacy of a 1:10 dilution of Lancy-Vaxina^((R)) (Berna Biotech, Switzerland), and were seen every 2-3 days (days 6, 8, 10, 13, and 15 after smallpox vaccination) for scheduled dressing changes. Swab specimens were obtained from the vaccination lesion, the outer surface, and the gauze surface. Quantitative viral culture assays for these specimens were done. Results : Vaccinia virus was recovered from 126 (81%) of the 156 vaccination lesion samples collected from the 40 participants. A high virus titer was recovered from the vaccination lesion (geometric mean titer (log_(10))=3.91 on day 8). Of the 39 swab samples obtained from the gauze surface of the gauze, 16 (41%) were positive for virus. An intermediate titer was recovered from the gauze surface (geometric mean titer (log_(10))=0.91 on day 8). Of the 133 swab samples obtained from the outer surface, only one (0.8%) was positive for vaccinia. No virus was recovered from the outer surface on day 8. Conclusion : Our findings suggest that the addition of a semipermeable dressing to the folded gauze further reduces viral shedding and therefore increases protection.
( Jee Whan Kim ),( Su Yeon Park ),( Yeo Jung Moon ),( Sei Kwang Kim ),( Sang Wook Bai ) 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-
목적: To compare recurrent prolapse after vaginal pelvic organ prolapse surgery in normal-weight compared with overweight and obese women. 방법: We performed a retrospective cohort study of the risk of recurrent prolapse after vaginal pelvic organ prolapse surgery (including vaginal hysterectomy, anterior vaginal colporrhaphy, posterior vaginal colporrhaphy or iliococcygeus fixation) in normal-weight compared with overweight and obese women at our institution from March 2011, through December 2012. We compared 4 groups: normal weight (BMI 18.5-22.9) compared with overweight (BMI 23.0-24.9), obese 1 (BMI 25.0-29.9) and obese 2 (BMI 30.0 or greater). Women with fewer than 6 months of follow-up and those with a prior prolapse surgery were excluded. Our primary outcome was a composite measure defined as anterior, posterior, or apical prolapse recurrence extending beyond the hymen or repeat treatment for symptomatic prolapse with surgery. 결과: We included 238 participants (82 [34%] normal-weight, 60 [25%] overweight, 88 [37%] obese 1 group and 8 [3%] obese 2 group women). There was no difference in age, vaginal parity, menopause, types of concomitant surgery, pre-operative POP quantification scores between 4 groups. And there was no difference in mean follow-up, 19.4±20.2 months in the normal weight compared with 21.5±18.0 in the overweight, 28.7±26.6 in the obese 1 and 17.8±24.6 in the obese 2 group (p=0.243). There was significant difference in recurrence; Prolapse recurred in 3.7% (n=3) of the normal-weight group, 1.7% (n=1) of the overweight group, 5.7% (n=5) of the obese 1 group and 25.0% (n=2) of the obese 2 group (p=0.028). Surgery for recurrent prolapse was performed in 5 women with symptomatic prolapse (p=0.737) and the most common site of recurrence was the anterior compartment [n=9] compared with the apical compartment [n=2] or posterior compartment [n=0] with no significant difference between 4 groups (p=0.132). 결론: After vaginal pelvic organ prolapse surgery, overweight or obese women have higher prolapse recurrence compared with normal-weight women. Anterior prolapse is the most common site of recurrence after vaginal pelvic organ prolapse surgery.
Nosocomial Transmission of Severe Fever With Thrombocytopenia Syndrome in Korea
Kim, Won Young,Choi, WooYoung,Park, Sun-Whan,Wang, Eun Byeol,Lee, Won-Ja,Jee, Youngmee,Lim, Kyoung Soo,Lee, Hyun-Jung,Kim, Sun-Mi,Lee, Sang-Oh,Choi, Sang-Ho,Kim, Yang Soo,Woo, Jun Hee,Kim, Sung-Han Oxford University Press 2015 Clinical Infectious Diseases Vol. No.
<P>Of the 27 healthcare workers (HCWs) who had contact with a fatally ill patient with severe thrombocytopenia syndrome in Korea (SFTS), 4 who were involved in cardiopulmonary resuscitation complained of fever and were diagnosed with SFTS via seroconversion. Exposure to respiratory secretions, blood, or gowns soiled by body fluids was significantly associated with infection of HCWs.</P>
Kim, Jae-Sung,Lim, Joo Han,Kim, Jee Hyun,Im, Seock-Ah,Chie, Eui Kyu,Hwang, Jin-Hyeok,Kim, Tae-You,Bang, Yung-Jue,Ha, Sung Whan,Yoon, Yong Bum Springer 2012 Cancer chemotherapy and pharmacology Vol.70 No.3
<P>5-FU-based concurrent chemoradiotherapy (CRT) has been the mainstay of treatment for locally advanced pancreatic cancer (LAPC) for the past decades, but the prognosis remains dismal.</P>