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Case Report : A Case of Perifollicular Fibroma
( Jae Hui Nam ),( Joon Hong Min ),( Ga Young Lee ),( Won Serk Kim ) 대한피부과학회 2011 Annals of Dermatology Vol.23 No.2
Perifollicular fibroma (PFF) is a very rare proliferative lesion of the perifollicular sheath. A flesh-colored, dome-shaped papulonodule is usually located on the face or the neck. These papulonodules may be single or multiple. Histologically, the lesion consists of a concentric arrangement of cellular fibrous tissue around a normal hair follicle. We describe here an unusual case of PFF in a 41-year-old female who had an asymptomatic small skin colored papule on the scalp, and this is an uncommon location for PFF. (Ann Dermatol 23(2) 236∼238, 2011)
Eccrine Hidrocystoma in a Child: An Atypical Presentation
Jae Hui Nam,Ga Young Lee,Won Serk Kim,Kea Jeung Kim 대한피부과학회 2010 Annals of Dermatology Vol.22 No.1
Eccrine hidrocystomas are small benign cystic lesions that normally affect only adult females. Eccrine hidrocystoma is characterized by tense vesicles that are predominately located on the face and particularly on the periorbital areas. Histologically, eccrine hidrocystoma consists of one or more partially collapsed unilocular cysts in the dermis, and these cysts are often situated adjacent to normal eccrine ducts. An 8-year-old boy presented with multiple skin-colored to bluish tiny papules on his nose. Histopathologically, the dilated partial cystic structures in the middermis were lined by one or two layers of flattened or cuboidal epithelial cells. We report here on an atypical presentation of multiple eccrine hidrocystomas that were localized on the nose of a child. (Ann Dermatol 22(1) 69∼72, 2010)
( Jae-hui Nam ),( Han-saem Kim ),( Ga-young Lee ),( Won-serk Kim ) 대한피부과학회 2017 Annals of Dermatology Vol.29 No.4
Background: Low fluence 1,064 nm Q-switched (QS) Neodymium:Yttrium-Aluminum-Garnet (Nd:YAG) laser treatment, also known as laser toning, is widely used for pig-mentary disorders. There has been no reliable evaluation of the effect of low fluence 1,064 nm QS Nd:YAG laser for se-nile lentigo. Objective: To investigate the beneficial effect of low fluence 1,064 nm QS Nd:YAG laser in the treatment of senile lentigo on the face. Methods: A retrospective review was conducted on patients treated only with repetitive low fluence 1,064 nm QS Nd:YAG laser. Among them, 12 pa-tients with multiple senile lentigines before treatment were included. All side effects were recorded to assess the safety of the modality. Results: Mean age was 56.1±7.8 years old and male-to-female ratio was 1:11. Mean treatment fluence was 1.62±0.16 J/cm<sup>2</sup> and mean total treatment session was 8.8±2.6. Mean interval period between each session was 28.0±11.4 days and mean treatment session to reach marked and near total improvement was 8.7±2.8. At the fi-nal visit, seven of 12 (58.3%) patients reached marked and near total improvement, and three of 12 (25.0%) reached moderate improvement. No side effects occurred. Conclusion: Repetitive low fluence 1,064 nm QS Nd:YAG laser treatment may be an effective and safe optional modality for senile lentigo. (Ann Dermatol 29(4) 427∼432, 2017)
( Jae-hui Nam ),( Han-saem Kim ),( Young Jun Choi ),( Ho Joo Jung ),( Won-serk Kim ) 대한피부과학회 2017 Annals of Dermatology Vol.29 No.4
Background: Nevus of Ota (NO) is a relatively common pig-mentary disorder in Asians. Tanino`s classification is an old but tacit consensus to delineate the disease. Various treat-ment options have been presented. However, a few studies have been conducted on available laser options and current treatment strategies or the classification of NO. Objective: To investigate current laser options and their effectiveness for the treatment of NO, contributing factors to clinical out-comes, and verification of classification. Methods: A retro-spective study of NO was conducted by reviewing medical charts and photographs of sixty-seven patients. Statistical analysis was used to compare excellent and poor outcomes and determine contributing factors. Results: The median age of onset was below the age of 1 (interquartile range [IQR], 0∼1). Tanino`s and PUMCH classification systems failed to classify patients in 24 (35.8%) and 6 (9.0%) of patients, respectively. A 1,064 nm Q-switched Nd:YAG laser without additional lasers was used most frequently in 42 patients (62.7%). The frequency of treatment was 19.0 (IQR, 10.0∼ 23.0) in the cured group defined as subjects showing 95% improvement or above, compared to 10.0 (IQR, 6.25∼ 13.75) in the unattained group defined as subjects showing less than 95% improvement (p=0.001). Conclusion: A 1,064 nm Q-switched Nd:YAG laser is a reliable treatment armamentarium, functioning as a single infallible modality as well as a combination treatment modality for NO. Repetitive laser treatments without interruption seems to be the most suitable in clearing NO. The current classification sys-tems of NO are defective. Thus, a new classification should be developed. (Ann Dermatol 29(4) 446∼453, 2017)
남재희 ( Jae Hui Nam ),이가영 ( Ga Young Lee ),김원석 ( Won Serk Kim ),김계정 ( Kea Jeung Kim ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.2
Syringoma is a common, benign, adnexal tumor of eccrine origin. Generalized eruptive syringoma, however, is a rare variant of syringoma which presents as a widespread papular eruption. It occurs in large numbers on the anterior parts of the neck, chest, abdomen, axillae, periumbilical region, or sometimes proximally on the extremities. It is as frequent in prepubertal as in postpubertal age. A 20-year-old woman presented with multiple asymptomatic papules on the face, neck, abdomen, back, upper and lower extremities. Family history showed that her mother had similar lesions on the abdomen. Histologically, numerous ducts are embedded in a fibrous stroma and their walls are lined by two rows of epithelial cells. We report a case of generalized eruptive syringoma. (Korean J Dermatol 2009;47(2):217∼219)
남재희 ( Jae Hui Nam ),최영준 ( Young Jun Choi ),김태환 ( Tae Hwan Kim ),이가영 ( Ga Young Lee ),김원석 ( Won Serk Kim ),김계정 ( Kea Jeung Kim ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.3
Sebaceous carcinoma (SC) is a slow-growing, locally aggressive tumor with the high potency of metastatic spread. This neoplasm frequently arises from the sebaceous glands of the eyelid and exceptionally from extraocular sites. Approximately one-quarter of all reported cases of SC are extraocular. We observed a 42-year-old woman with an crusted erythematous to brownish plaque on her scalp. The biopsy specimen showed that multiple lobules were composed of foamy-cytoplasmic cells and sebocytes which show pleomorphism and atypia. For the immunohist-ochemistry, abundant tumor cells (with the expressions of epithelial membrane antigens and cytokeratin) were found within the masses. We present here a case of SC of the scalp arising from a previous lesion clinically compatible with a nevus sebaceous. (Korean J Dermatol 2009;47(3):326∼329)
남재희 ( Jae Hui Nam ),최영준 ( Young Jun Choi ),김태환 ( Tae Hwan Kim ),이가영 ( Ga Young Lee ),박수홍 ( Soo Hong Park ),김원석 ( Won Serk Kim ),김계정 ( Kea Jeung Kim ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.6
Background: Keloid is one of the most frustrating clinical problems in wound healing. There are numerous treatments for keloids such as surgical excision, steroid injection, radiation therapy, laser, silicone gel application and so on. Surgical excision of a keloid is generally not accepted as a first treatment of choice. However, there have been many reports of successful cosmetic results from specialized surgical treatments such as intra-lesional/intra-marginal excision with or without post surgical adjuvant treatments. Objective: The aims of this study areto evaluate the effectiveness of intralesional excision of keloids, the optimal surgical conditions and the proper adjuvant therapy after surgery. Methods: We analyzed the medical records and clinical photographs of 20 patients who underwent intra-lesional excision of their keloids and who had regular follow-ups for at least for 3 months. The clinical outcomes were assessed by three independent physicians based on their interpretation of the photographs before and after surgery with using a global assessment 5 point scale that ranged from bad, poor, fair and good to excellent. Results: General surgical outcomes after intra-lesional excision: the average improvement score was 4.05 after intra-lesional excision and adjuvant therapy. The average improvement score after intra-lesional excision was 4.71 for ear keloids and 2.83 for keloids in other areas (p=0.000). The average improvement score after intra-lesional excision was 5 for earlobe keloids and 4.42 for ear-helix keloids (p=0.014). The average improvement score was 3.92 for the steroid intra-lesional injection and topical silicone gel combination treatment group after intra-lesional excision and the average improvement score was 4.29 for the single topical silicone gel treatment group (p=0.858). Conclusion: Although surgery is not a first treatment of choice for the management of keloids, large recalcitrant keloids need massive surgical removal for faster clinical results. In this study, we found that surgery, and especially intra-lesional excision, is not an absolute contraindication for treating keloids and this is sometimes considered as the first treatment of choice, and especially for ear keloids. However, a more careful surgical approach is necessary for the case of keloids that develop in other areas. Further studies about the optimal surgical indications for keloids and the recommended adjuvant therapy after surgery are necessary. (Korean J Dermatol 2009;47(6):641∼648)