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      • KCI등재

        요구원 후기시의 탈원근법적 주체와 시각의 형이상학

        오연경(Oh, Youn-kyung) 한국시학회 2013 한국시학연구 Vol.- No.36

        The Kyuwon Oh’s later poems, so called a ‘raw image poetry’ are based on a new alternative visual regime as a challenge to the anthropocentric perspective regime. The post-anthropocentricism of Kyuwon Oh’s poems proceeds from a denial of signifying or naming subject and such a subject-centered language. So the raw image poetry cannot but make into question not only a notion sticked to a language but also a notion sticked to a view. In this question, the main issue is a perspective hypothesis which establish a basis of subjectivity and rationality in anthropocentricism. Thus the raw image suggested by Kyuwon Oh is not a phenomenon of things in the raw, but an alternative hypothesis, that is a language of post-perspective vision against the conventionalized hypothesis sticked to things, This paper examines in reference to the post-perspective vision, the methodology of the raw image poetry which aims to make a language in contact to phenomenon of things by an innovation of perception. Therefore this paper would demonstrate that the keys to methodology of the raw image poetry are the post-perspective vision by analyzing in detail three points of writing poetry, ⑴ to make an another visual notion by eliminating a perspective depth, ⑵ to rearrange a routine visibility by reversing the principles of forms and backgrounds, ⑶ to create a metaphysical vision by realizing a frame-internal subject. It brings us a new ability of vision to see the things which are assigned to the invisible. The new ability of vision provides a ‘metaphysics of vision’ which visualizes a metaphysical longing for infinities of the world. The metaphysics of vision is considered as a kind of artistic utopia to overcome a problematic modernity in the society of fetishism. The raw image poetics of Kyuwon Oh can be appreciated in terms of a denial of perspective regime which establish a basis of subjectivity and rationality and a creation of metaphysical vision as counterplans for the perspective regime.

      • Combustion characteristics of gaseous inverse O<sub>2</sub>/H<sub>2</sub> coaxial jet flames in a single-element model combustor

        Kim, Tae Young,Choi, Sun,Kim, Young Hoo,Ahn, Yeong Jong,Kim, Hee Kyung,Kwon, Oh Chae Elsevier 2018 ENERGY Vol.155 No.-

        <P><B>Abstract</B></P> <P>To effectively design hydrogen (H<SUB>2</SUB>)/oxygen (O<SUB>2</SUB>) liquid rocket engines through understanding the combustion characteristics of H<SUB>2</SUB>/O<SUB>2</SUB> bipropellants, fundamental studies for the bipropellants in different phases are needed. This study is focused on the combustion characteristics of inverse gaseous O<SUB>2</SUB>/H<SUB>2</SUB> coaxial jet flames in a single-element model combustor as a preliminary step for succeeding studies of injection at different phases in the combustor, visualizing flame structure by direct imaging, OH<SUP>∗</SUP> chemiluminescence and OH planar laser-induced fluorescence. With increasing Reynolds number (Re), the frequency of occurrence of the local flame extinction increases and the length of the disconnected OH reaction zone is extended. The OH layer thickness increases downstream, while it is almost constant where the local flame extinction occurs and decreases with increasing Re due to the enhanced strain and scalar-dissipation rates. The excessive flame wrinkledness increases the local flame strain rate and results in the local flame extinction, exhibiting the tendency of increasing and then decreasing flame surface density with increasing Re. The probability density function of OH intensity quantifies the fluctuation intensity of OH radicals and the possibility of the local flame extinction. A useful database is provided for modeling the combustion of H<SUB>2</SUB>/O<SUB>2</SUB> bipropellants under different phases.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A useful database for modeling the H<SUB>2</SUB>/O<SUB>2</SUB> bipropellant combustion is provided. </LI> <LI> Local flame extinction frequently occurs at high Reynolds number (<I>Re</I>). </LI> <LI> OH probability density function indicates the possibility of local extinction. </LI> <LI> Flame surface density increases and then decreases with increasing <I>Re</I>. </LI> <LI> Strong burning of O<SUB>2</SUB>/H<SUB>2</SUB> causes laminar-like combustion near the injector lip. </LI> </UL> </P>

      • 생약제제인 이공산(異功散)의 Cisplatin 유도 신장독성 보호 및 항산화 효과

        Lee, Kyung-Tae,Ahn, Kyoo-Seok,Chang, Sung-Goo,Oh, Soo-Myung,Jung, Jee-Chang 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

        Kyung-Tae Lee, Kyoo-Seok Ahn¹, Sung-Goo Chang², Soo-Myung Oh²and Jee-Chang Jung²¹College of Pharmacy, ²Oriental Medicine and ³College of Medicine, and East-West Medical Reserch Institute, Kyung Hee University, Seoul, Korea. Preventive and Antioxidative Effects of Crude Drug Preparation(E-kong-san) on Cisplatin Induced Nephrotoxicity. Proceedings of International Symposium on East-West Medicine, Seoul. 201-211, 1999. -Nephroprotective effects of a crude drug-prearation (E-kong-san) were determined from cisplatin on rabbit kidney proximal tubule and human renal cortical cells by MTT assays and sustained glucose consumption on ciplatin-induced human renal cortical tissue. Levels of creatinine and blood ure nitrogen(BUN) in serum after administration of cisplatin(0.75mg/kg,i.p.) to E-kong-san(0.75g/kg/day,p.o.)-pretreated rats were markedly lower compared to those of cisplatin-treated rats. Moreover, the administration of E-kong-san significantly inhibited the loss of body weight of cisplatin injected rts. These findings suggest that E-kong-san on the cisplatin induced nephrotoxicity led us to investigate whether the effect of this water extract was a result of anti-oxidation. E-kong-san showed strong free radical scavenger activities on 1,1-dipheny1-2picrylhydrazil(DPPH) radical and xanthine/xanthine oxidase(XOD) generated superoxide anion radical(O2-). We further studied the effects of E-kong-san on lipid peroxidation in rat liver microsomes induced by enzymatic and nonenzymatic methods. E-kong-san exhibited significant inhibition on both ascorbic acid/Fe2+and ADP/NADPH/Fe3+ induced lipid peroxidation in rat liver microsomes. Based on these results, we suggest that-E-kong-san attenuate the cisplatin induced cytotoxicity and its mechanism can be eplained by antioxidant.

      • KCI등재

        영남권 민요의 전승과 특질 연구 : 전이지역을 중심으로 on the point of transition area

        권오경 우리말글학회 2003 우리말 글 Vol.29 No.-

        Traditional folk-song of Yungnam province is classified in six ranges and has seven transition area. This paper is prepared to study transmission and qualities of these transition area's folk-song. As a result, I could got as following; For example, the transition area of between the west of Kyung-Book province and of Kyung-Nam province has special qualities in the field of between Buddhism and Confucianism, Man and woman, mountain and plain. The representative folk-song are <Eusayong> and <a pallbearers' dirge> and <Bacmeneunsori>. This is for the mutual assistance or keep away from competition of each others. And This is similar phenomenon in other transition area. The transition area of between the west and south of Kyung-Nam province has mixing culture on the mountain and plain. And the <Yong-he-ya>-barley threshing song- is from the dynasty of Gaya. The transition area of between the north center and east of Kyung-Book province is special on the point of rice-planting song which is related with the worship of the god of the earth and with the closed style in sing a song.(Pusan University of Foreign Studies)

      • KCI등재

        제주도 지하수 질산염 농도의 시·공간적 변화 특성: 장기(1993-2015) 모니터링 자료의 평가

        김호림(Ho-Rim Kim),오준섭(Junseop Oh),도현권(Hyun-Kwon Do),이경진(Kyung-Jin Lee),현익현(Ik-Hyun Hyun),오상실(Sang-Sil Oh),감상규(Sang-Kyu Kam),윤성택(Seong-Taek Yun) 대한자원환경지질학회 2018 자원환경지질 Vol.51 No.1

        1993년부터 2015년까지 관측된 제주도 지하수 장기모니터링 관측정(N = 4,835)에서 수집된 지하수 수질자료(N = 21,568)를 기반으로 질산성질소의 시공간적 변동 특성을 평가하였다. 제주도 지하수의 질산성질소 농도의 중앙값은 2.5 mg/L로서 다른 국가나 대륙의 조사 결과에 비해 다소 높거나 유사한 것으로 나타났다. 또한 지하수 용도, 행정구역 및 고도 별로 유의한 차이를 보였다. 특히, 산간 지역에 비해 저지대 해안가에 위치한 농업 및 주거지역에서 농도가 높음을 확인하였다. Mann-Kendall 및 Sen’s slope 분석을 활용한 질산성질소 농도의 추세 분석 결과, 하류 저지 대에 비해 중산간지역에서의 질산성질소 농도 증가 경향이 뚜렷하였다. 제주도 내 토지 피복의 시계열 변화 특성과 결부 지어 보면, 중산간지역의 오염 증가 추세는 농업지역의 확장 등 인위적 활동 증가에 기인한 결과로 판단된다. 반면,기지정된 지하수자원특별관리구역에서는 전반적으로 질산성질소 농도의 감소 경향이 나타났는데, 이는 지하수 관리 측면에서 수질관리를 위한 적극적인 정책이 유효함을 시사한다. 본 연구에서는 제주도 지하수의 질산성질소 오염관리를 위한 적정 방안을 제안한다. The spatio-temporal variations of nitrate concentrations in groundwater of Jeju Island were evaluated by an analysis of time series groundwater quality data (N = 21,568) that were collected from regional groundwater monitoring (number of wells = 4,835) for up to 20 years between 1993 and 2015. The median concentration of NO 3 -N is 2.5 mg/L, which is slightly higher than those reported from regional surveys in other countries. Nitrate concentrations of groundwater in wells tend to significantly vary according to different water usage (of the well), administrative districts, and topographic elevations: nitrate level is higher in low-lying agricultural and residential areas than those in high mountainous areas. The Mann-Kendall trend test and Sen’s slope analysis show that nitrate concentration in mid-mountainous areas tends to increase, possibly due to the expansion of agricultural areas toward highland. On the other hand, nitrate concentrations in the Specially Designated Groundwater Quality Protection Zones show the temporally decreasing trend, which implies the efficiency of groundwater management actions in Jeju. Proper measures for sustainable groundwater quality management are suggested in this study.

      • 모델연소실 내 GCH₄/GO₂ 및 GH₂ /GO₂ 동축류 제트화염의 연소특성 기초 연구

        최선(Sun Choi),김태영(Tae Young Kim),김희경(Hee Kyung Kim),권오채(Oh Chae Kwon) 한국추진공학회 2016 한국추진공학회 학술대회논문집 Vol.2016 No.12

        로켓 엔진의 차세대 액체이원추진제로서 각광을 받고 있는 메탄(CH₄)/산소(O₂) 이원추진제의 기초연소특성 및 연소 안정화의 고유특성 확인을 위해 수소(H2)/산소 이원추진제 연소특성과 비교 연구를 수행하였다. 기초 연소특성 연구를 위한 모델연소실 내에서 기체 메탄(GCH₄)/기체 산소(GO₂) 및 기체수소(GH₂)/GO₂의 동축류 제트화염의 연소안정한계와 직접 사진, OH<SUP>*</SUP> 자발광 이미지를 측정한 결과, GCH₄/GO₂와 GH₂/GO₂ 모두 산소-연료 모멘텀비((O/F)mom)가 감소함에 따라 연소안정한계는 확장되는 경향을 보였으나 GH₂/GO₂ 화염에 비해 GCH₄/GO₂ 화염은 좁은 연소안정한계가 측정되었고, 또한 GCH₄/GO₂ 화염은 이론당량비 조건에서, GH2/GO₂ 화염은 연료과농 조건에서 최대 OH* 강도가 측정됨을 OH<SUP>*</SUP> 자발광 가시화를 통해 확인하였다. Liquid methane (CH₄)/oxygen (O₂) bipropellants have been recently considered as a next-generation propellant due to eco-friendly and non-toxic properties, low cost and high performance. To investigate the unique features of CH₄/O₂ bipropellants, the fundamental combustion characteristics of gaseous CH₄/O₂ and H₂/O₂ coaxial jet flames in a model combustor are investigated through measuring the combustion stability limits and visualizing flames. Results show that the combustion stability limits of GCH₄/GO₂ flames are reduced compared with the GH₂/GO₂ flames. The maximum OH<SUP>*</SUP> intensity of GCH₄/GO₂ flames is observed at near-stoichiometric condition, while the GH₂/GO₂ flames at fuel-rich condition.

      • KCI등재

        Association of 20 potential ATP2B1‐interacting genes with blood pressure in Koreans

        Kyung‐Won Hong,Hyun‐Seok Jin,Ji‐Eun Lim,Bermseok Oh 한국유전학회 2011 Genes & Genomics Vol.33 No.3

        Plasma membrane calcium‐transporting ATPase 1 (ATP2B1)is associated significantly with blood pressure in Caucasians and Asians. ATP2B1 regulates calcium homeostasis and belongs to the P‐type calcium pump family; several studies have identified diverse proteins that bind to ATP2B1. We hypothesized that ATP2B1 regulates blood pressure through ATP2B1‐interacting genes. To this end, 20 potential ATP2B1‐interacting genes were selected, 197 SNPs of which were analyzed for their association of systolic and diastolic blood pressure. These 20 genes were categorized into 2 groups: ATP2B1‐binding genes and ATP2B1‐cleaving calpain family members. Three ATP2B1‐binding genes (CALM1, NOS1, and PDLIM1)were associated with blood pressure, and a SNP in CALM1(rs2401887) generated the strongest association signal (beta=‐3.60±0.92, p=8.9×10^(‐5) for systolic blood pressure and beta=‐1.40±0.62, p=0.02 for diastolic blood pressure). Of the calpain family members, 3 genes (CAPN6, CAPN9, and CAPN10)were associated with blood pressure, and the CAPN10 SNP rs4676348 yielded the strongest association signal (beta=‐0.88±0.27, p=0.001 for systolic blood pressure and beta=‐0.58±0.18, p=0.015 for diastolic blood pressure). Further, the interaction of CALM1 to ATP2B1 was examined using the blood pressure of individuals who carried both variants of CALM1and ATP2B1 genes. Similarly the interaction of CAPN10 to ATP2B1 was also examined. The CALM1 variant (rs2401887)and CAPN10 variants (rs4676348) appear to decrease blood pressure further in addition to the decrease by the variant (rs17249754) of ATP2B1, which suggests that ATP2B1 might regulate blood pressure through the ATP2B1‐interacting genes CALM1 and CAPN10.

      • 당뇨병-고지혈증 모델동물의 개발

        오승현,노경진,박인선,민본홍,두호경,안세영,김용석,성제경 한국환경독성학회 2004 환경독성보건학회지 Vol.19 No.3

        Diabetic complication is one of major risk factors leading to vascular disease Such as atherosclerosis stroke, coronary heart disease and etc Several factors affecting the acceleration of diabetic vascular complication have been known such as hypertension hyperlipidemia, immune complex and genetic factors To screen and develop new therapeutics agents for diabetic vascular complication, it is strongly needed to develop animal models for diabetic complications However in rodents models, diabetic complications is not well developed Furthermore to asses¢ the possibility of new therapeutics for diabetic vascular complications, diabetic animal models which have the risk factors of diabetic complications is needed We aim to develop and establish an diabetic animal model which have diabetic complications with hyperlipidemia which is one of risk factors for diabetic complications We induced insulin-dependent diabetes by intra venous injection of streptozotocin (35 mg/kg/day) in RICO rats which is a spontaneous animal model for hyperlipidemia Our models (STZ RICO) showed hyperglycemia, persistent high level of plasma cholesterol and triglyceridemia with severe diabetic renal changes until 28 weeks after induction of diabetes STZ-RICO rats could be used for the evaluations of newly developed diabetic drugs.

      • KCI등재

        Analysis of KAP1 expression patterns and human endogenous retrovirus Env proteins in ovarian cancer

        Kyung‑Yoon Jeon,Eun‑Ji Ko,Young Lim Oh,Hongbae Kim,Wan Kyu Eo,김아리,Han Gyu Sun,Meesun Ock,Ki Hyung Kim,Hee‑Jae Cha 한국유전학회 2020 Genes & Genomics Vol.42 No.10

        Background Human endogenous retroviruses (HERVs) constitute around 8% of the human genome and have important roles in human health and disease, including cancers. Previous studies showed that HERV envelope (Env) proteins are highly expressed in cancer tissues and co-related with cancer progression. KAP1 has been reported to play a key role in regulating retrotransposons, including HERV-K, through epigenetic silencing. Objective The relationship between KAP-1 and HERV Envs expressions was analyzed only in tumor cell lines and has not yet been studied in cancer tissues. In this study, we analyzed the expression patterns and relationship between KAP1 and HERV Env proteins in ovarian cancer tissues. Method The expression patterns of KAP-1 and HERV Env proteins, including HERV-K and HERV-R, were analyzed in ovarian cancer tissue microarrays that contained 80 surgical specimens, including normal ovary and malignant ovarian cancers. Results The expression of HERV-R Env and KAP1 proteins is signifcantly higher in ovarian cancer compared with normal ovary tissues. However, the expression of HERV-K Env did not change signifcantly in cancer tissues. The expression patterns of HERV-K Env and HERV-R Env signifcantly increased in early stages of cancer and KAP1 expression was higher in certain stage and types of cancers. However, the expression of HERV-K Env, HERV-R Env, and KAP1 did not change in diferent age groups. The correlation between the expression of KAP1 and HERV-Env, including HERV-K and HERV-R, was not signifcantly correlated. Conclusions The results of this study showed that there was no signifcant correlation between the expression of KAP1 and HERV Env proteins in ovarian cancer tissues, unlike studies with cell lines in vitro. These results suggest that the actual expression of HERV Env proteins in ovarian cancer tissues may be regulated through various complex factors as well as KAP1.

      • SCOPUSKCI등재

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