림프질 전이가 있는 하인두암과 하부식도암의 진단에 활용된 내시경초음파 유도하 Trucut 생검 1예

광명옥,이정환,문정섭,김유선,류수형,총배천,김형훈,김현태 仁濟大學校 白病院 2010 仁濟醫學 Vol.31 No.-

The incidence of double primary cancer is about 10% in all kinds of cancers. Double primary cancer is usually accompanied by gastrointestinal cancer. Esophageal cancer is supposed to be frequently accompanied by squamous cell carcinoma of the head and neck or the upper respiratory tract, because of such common carcinogens as smoking and alcohol ingestion. Esophageal cancer and hypopharyngeal cancer are usually diagnosed by esophagogastric endoscopy with biopsy. We performed endoscopic ultrasound-guided Trucut biopsy(EUS-TCB) to diagnose a mediastinal mass in a 49 year-old patient, who visited our hospital because of voice change. During procedure, we accidently found enlarged celiac lymph node, and obtained tissue from the mediastinal lymph node and the celiac lymph node. We confirmed double primary cancer of squamous cell carcinoma in the esophagus and the hypopharynx via esophagogastric endoscopy.

치근이개부 감염에 관한 임상적 연구

김형섭 全北大學校 齒醫學硏究所 1985 전북치대논문집 Vol.3 No.1

The author studies the incidence, age, Glickman's classification of the maxillary and mandibular molars with furcation involvement by radiographic and clinical examination. The data for this study was 369 maxillary and mandibular molars of 40 patients (male 17, female 23) of Dentistry, J.N.U. Hospital. The results were as follows. 1. The mean average age of the patients was 43. The average number of the maxillary and mandibular molars in each patient was 4.5. 2. The incidence of furcation involvement for 185 maxillary molars and 184 mandibular molars was shown in 76 maxillary molars (40%) and 79 mandibular molars (42.9%). 3. The incidence of Glickman's classification of furcation involvement was shown in 73 Grade Ⅱ, 43 Grade Ⅲ, 25 Grade Ⅳ, 14 Grade Ⅰ.

악관절 융기 증강술을 통한 습관성 악관절 탈구환자의 치험례

김일규,신주호,오성섭,최진호,김형돈,오남식,김의성 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.2

Recurrent mandibular dislocation is frequent morbidity of temporomandibular joint relatively. There are many etiologic causes in TMJ disorders but, difficult to find obvious one. Various treatment methods have been utilized for a mandibular dislocation. It is categorized into two groups broadly - nonsurgical or surgical methods. The basic rationale of the surgical method is to allow free movement of the condyle by reducing height of articular eminence or to limit anterior excessive movement of the condyle by increasing height of articular eminence or soft tissue anchoring procedure. In this case, 69 year-old woman was treated by augmentation of the articular eminence with mandibular symphysial bone graft leading to osteosynthesis without difficulty. As a result, favorable postoperative outcome was obtained functionally without any complication or recurrence.

Arachidonic acid 대사산물의 골흡수능

김형섭,오귀옥,장기완 대한구강생물학회 1991 International Journal of Oral Biology Vol.15 No.2

This experiment was performed to study the effect of the arachidonic acid metabolites(PGE_2, LTB_4, HETEs) on the bone resorption in the organ culture. The observed results were as follows: 1. PGE_2, at concentration of 10^-6M, increased ^45Ca release significantly after 72 hours of culture. 2. LTB_4 or HETEs, at all concentrations, had no effect on the bone resorption after 72 hours of culture. 3. LTB_4 or HETEs did not change the bone resorbing activity of PGE_2 bone resorption after 72 hours of culture.

유리자가 치은 이식술을 이용한 부착치은 확대의 증례보고

김형섭 全北大學校 齒醫學硏究所 1983 전북치대논문집 Vol.1 No.1

To increase the attached gingiva and deepen the vestibular fornix, the author applied to use free gingival autograft procedure in the right premolar area in 43 years old male patients without systemic complication. Donor site for free gingival autograft procedure was determined to obtain upper palatal mucosa with Omar Paquett knife. Positioned the autograft and adaptedit firmly to the recipient site. Used a minimum number of sutures to avoid unneccessary tissue penetration. Grafted mucosa was covered with COE-pak for lweek and clinical evaluation was performed until 2 weeks after surgery. After postoperative 2 weeks, grafted mucosa was seen relatively normal gingival color and appeared like attached gingival architecture on clinical observation. During postoperative period, patient was no complain of the surgical site and periodontal eviornment of the patient was improved.

치주질환에 있어서의 조직파괴인자 및 억제약물에 대한 연구

김오환,김형섭,오귀옥 대한구강생물학회 1988 International Journal of Oral Biology Vol.12 No.2

Arachidonic acid(AA) metabolites are known to play an important role in the development of inflammation and pathogenesis of periodontal disease. The bone resorbing activity of PGE_2 and elevated level of prostaglandins and thromboxane in inflamed gingiva, which are cyclooxygenase(C) products, has been well documented. However, since recent studies provide evidence that gingival tissue metabolizes AA mainly through lipoxygenase(L) pathway, we have started this study to show the exact profile of AA metabolism in gingival tissue. Fourteen individual periodontal pocket tissue(PPT) samples were obtained from patients with advanced periodontitis and incubated separately with ^14C-AA(0.2μCi). The tissue lipid extracts were separated by means of thin layer chromatography(TLC), and analyzed by means of autoradiography and TLC analyzer. Our work show that ^14C-AA metabolism in PPT is mainly via the L pathway(L products/C products=6.17) and that 12-HETE & 15-HETE(55.73% of total formed metabolites), to a lesser extent 5-HETE(6.21%), are the major L products formed. C products thromboxane B_2 (4.32%), 6-keto-PGF_1α & PGE_2 (4.42%) were also detected in much smaller amounts than L products. Indomethacin well-known C inhibitor, also inhibited L as well as C, that is the result similar to the reports of Paajanen et al.(1982) and Lessard et al.(1986). This phenomenon is being further investigated by use of partially purified L system.

忠北地域의 배추좀나방 系統에 대한 殺蟲劑에 관한 硏究

金舜燮,李炯來 충북대학교 농업과학기술연구소 1993 農業科學硏究 Vol.10 No.2

The experiment was carried out by the spray method to investigate the insecticidal resistance of the susceptible and the collected strains of the diamondback moth, DBM(Plutella xylostella L.)in Chungbuk Province. The results are summarized as follows. 1.In Chlorpyrifos, the LC50 values(ppm) of the susceptible(s-strain), Cheongwon, Ockcheon, Boeun, Jungwon, Koesan, Yeongdong and Jewon strains were 11.5, 18.2, 39.8, 42.2, 141.6, 154.0, 173.8, and 224.9, respectively. The resistance of the Jewon strain was 19.6 times greater than that of the s-strain. 2.In Methomyl, the LC50 values(ppm) of the susceptible, Cheongwon, Boeun, Jewon, Koesan, Jungwon, Ockcheon and Yeongdong strains were 0.94, 57.1, 83.0, 97.4, 148.6, 240.8, 286.9 and 512.4, respectively. The Yeongdong strain showed the highest resistant level among the collected strains. The LC50 values of the Yeongdong, Ockcheon, Jungwon, Koesan and Jewon strains were at least 100 times greater than that of the s-strain. 3.In Carbaryl, the LC50 values(ppm) of the susceptible, Ockcheon, Boeun, Koesan, Yeongdong, Jewon, Cheongwon, and Jungwon strains were 36.3, 69.6, 141.3, 256.3, 269.9, 884.9, 2224.8 and 34 14.3, respectively. The LC50 values of the Jungwon strain was 94.1 times greater than that of the s-strain. 4.In Deltamethrin, the LC50 values(ppm) of the susceptible, Boeun, Ockcheon, Cheongwon, Yeongdong, Jewon, Jungwon, and Koesan strains were 9.3, 23.8, 30.9, 31.4, 52.0, 55.9, 67.4 and 99,6, respectively. The LC50 value of the Koesan strain was 10.7 times greater than that of the s-strain. 5.In Fenvalerate, the LC50 values(ppm) of the susceptible. Yeongdong, Jungwon, Boeun, Cheo-ngwon, Koesan, and Jewon strains were 9.7, 44.4, 72.1, 78.5, 92.0, 186.8 and 245.1, respectively. The LC50 value of the Jewon strain was 25.2 times greater than that of the s-strain. 6.In Cartap, the LC50 values(ppm) of the susceptible, Ockcheon, Koesan, Yeongdong, Jungwon, Boeun, Jewon, and Cheongwon strains were 18.5, 24.3, 25.8, 119.3, 128.5, 130.2, 132.6 and 384.0, respectively. The LC50 value of the Cheongwon strain was 20.7 times greater than that of the s-st-rain.

Cone beam형 전산화단층촬영법을 이용한 하악과두의 골변화에 관한 연구

이지운,김형섭,송주섭,김경아,고광준 대한구강악안면방사선학회 2007 Imaging Science in Dentistry Vol.37 No.3

Purpose : To assess bone changes of mandibular condyle using cone beam computed tomography (CBCT) in temporomandibular disorder (TMD) Patients. Materials and Methods : 314 temporomandibular joints (TMJs) images of 163 TMD patients were examined at the Department of Oral and Maxillofacial Radiology, Chonbuk National University. The images were obtained by PSR9000N (Asahi Roentgen Co., Japan) and reconstructed by using Asahivision software (Asahi Roentgen Co.,Japan). The CBCT images were examined three times with four weeks interval by three radiologists. Bone changes of mandibular condyle such as flattening, sclerosis, erosion and osteophyte formation were observed in sagittal, axial, coronal and 3 dimensional images of the mandibular condyle. The statistical analysis was performed using SPSS 12.0. Intra-and interobserver agreement were performed by 3 radiologists without the knowledge of clinical information. Results : Osteophyte (2.9%) was found more frequently on anterior surface of the mandibular condyle. Erosion (31.8%) was found more frequently on anterior and medial surfaces of the mandibular condyle. The intraobserver agreement was good to excellent(k=0.78-0.84), but interobserver agreement was fair(k=0.45). Conclusion : CBCT can provide high qualified images of bone changes of the TMJ with axial, coronal and 3 dimensional images.

도암호의 수화현상과 환경요인분석

전방욱,김형섭,김형근 강릉대학교동해안지역연구소 1993 東海岸硏究 Vol.4 No.3

수화를 일으키는 원인종을 찾고, 수화에 미치는 각각의 환경요인의 영향을 밝히기 위하여 요인분석을 시도하였다. 수화를 일으키는 원인종은 Microcystis aeruginosa로 밝혀졌다. 제1요인은 식물성 플랑크톤에 의한 수화와 관계가 있었는데 이는 엽록소 a에 대한 인자부하량이 +0.93으로 나타났기 때문이다. 식물성 플랑크톤은 호소표층수에서 인을 소모시키는 것으로 나타났으며 pH, 부유물질량, 탁도등을 증가시켰다. 제2요인은 유기오염과 관계가 있었는데 이는 생물화학적 산소요구량과 대장균군수의 인자부하량이 각각 +0.68과 +0.78로 나타났기 때문이다. The water bloom forming species were investigated, and factor analysis was applied to scrutinize the influence of different environmental factor on water blooming. The water bloom forming species was identified as Microcystis aeruginosa. The first factor was phytoplankton blooming, because it has positive loadings for chlorophy11 a (+0.93). It showed that phytoplankton cause deprivation of phosphorus from lake surface water and increases of pH, suspended solid and turbidity. The second factor was organic pollution because it has positive loadings for biochemical oxygen demand (+0.68) and MPN (+0.78).

영동지역 4개 저수지의 식물성 플랑크톤 분포에 의한 오수생물학적 연구

박영제,김양배,전방욱,김형섭 江陵大學校東海岸地域硏究所 1993 東海岸硏究 Vol.4 No.1

영동지역에 위치하는 4개 저수지를 대상으로 1991년 9월에 수질조사 및 식물성 플랑크톤 분포에 의한 오수생물학적 수질평가 연구를 시도하였다. 수질평가를 위하여 수온, 수소이온농도, 총질소, 총인, 엽록소 a, 및 식물성 플랑크톤의 현존량을 조사하였다. 동정된 식물성 플랑크톤은 총 58종류로 남조류 10종, 황색편모조 1종, 와편모조 2종, 갈색편모조 1종 및 녹조류 37종류였다. 식물성 플랑크톤의 우점종은 저수지별로 달랐으며, 죽헌저수지는 Microsystis aeruginosa, 북동저수지는 Peridinium cunningtonii var. contactum, 달방댐은 Staurastrum simonyi var. simonyi, 초당저수지는 Chlamydomonas umbonata로 밝혀졌다. 수질 및 식물성 플랑크톤의 분포유형을 기준으로 호수 수질을 생물학적으로 판정할 때 죽헌, 북동 및 초당저수지는 β-중부수성 호수로 달방댐은 빈부수성 호수로 판정되었다. The survey of water quality and saprobiotic phytoplankton distribution was carried out in 4 reservoirs in eastern area of Kangwon Province at September 1991. Temperature, pH, total-N, total-P, chl.a, and standing crop of phytoplankton were measured for water quality examination. Total numbers of phytoplankton identified were 58 spp, consisted of 10 spp Cyanophyta, 1 spp Chrysophyta, 2 spp Dinophyta, 1 spp Crytophyta, and 37 spp Chlorophyta. The dominant species of phytoplankton in each reservoir was different as follows: Microsystis aeruginosa in Jukhean, Peridinium cunningtonii var. contactum in Bukdong, Staurastrum simonyi var. simonyi in Dalbang, and Chlamydomonas umbonata in Chodang. Estimated from the data of water quality and phytoplankton distribution, the reservoirs of Jukheon, Bukdong and Chodang were β-mesosaprobic whereas Dalbang was oligosaprobic.