커패시터 放電 임펄스 着磁機 및 着磁 요크시스템의 定數算定에 관한 硏究

白壽鉉,金 龍,金必洙,尹秀鳳,朴永浩,尹信容 동국대학교 대학원 1992 大學院硏究論集-東國大學校 大學院 Vol.22 No.-

In a capacitor-discharge impulse magnetizer, a magnet is magnetized by the discharging current of capacitor The actual construction of magnetizing fixtures and discharge matching is expensive and time-consuming. Since the parameters of the impulse magnetizer have been determined and the resistance and inductance of such a magnetizing fixture can be easily computed using FEA, it is possible to predict the performance of such a fixture without actually building it. This paper describes that by mathematically modeling the capacitor-discharge impulse magnetizer fixture the problem can be solved with resonable predictability. The basic equations are presented and used to predict the magnetic-field intensity inside the fixtures. Finite-Element-Analysis is also used as part of the design process

제조가 사염화탄소에 의해 유도된 흰쥐의 지질함량에 미치는 영향

윤수홍,김덕현,김준수 한국위생과학회 2001 한국위생과학회지 Vol.7 No.2

사염화탄소(CCl_4)는 가축의 구충제, 용매, 지용성, 비가연성, 비휘발성 세제 및 소화제로 널리 사용되어온 할로겐 화합물^14)로 사람을 비롯한 모든 종에 대하여 간손상을 일으키는 대표적인 약물로 알려져 있다. 사염화탄소의 간장 독작용에 관한 기전은 명확히 규정되어 있지 않으나 alkylating radical을 지닌 간장 독성물질로 규정하는 세포 파괴설^15)로 사염화탄소를 투여하면 cytochrome P450 monooxygenase에 의하여 전자를 공급받아 trichloromethyl free radocal(CCl_3·)로 대사되어 세포내 단백질, 지질 및 기타 거대분자 등과 결합하여 단백질을 불활성화시키거나 효소활성을 감소시키거나^16~19) trichloromethylperoxy free radical(CCl_3OO·)로 산화되어 세포막의 불포화 지방산을 과산화시켜 막의 구조와 기능을 파괴하여 간에서 단백합성을 저해하고^20,21) 간장 glycogen양을 감소시키며, 혈중으로 AST 및 ALT 등의 유출을 일으키고 또한 조직학적으로는 간장조직의 지방변성과 괴사 등을 일으킨다고 알려져 있다.^22,23) 한편 혈액의 분산과 기관지 해소작용 등이 있어 각종 염증 및 기관지 치료에 사용되는 한방약제인 제조을 사용하여 흰쥐에게 사염화탄소를 투여하여 혈청 지질함량에 미치는 영향을 알아보고자 실험을 하였다. 사염화탄소 투여에 의하여 흰쥐 혈청의 지질함량이 전반적으로 증가하였는데 특히 중성지방의 증가가 현저하였으며 증가한 지질함량은 제조 수침액을 투여함으로써 양호하게 감소하였다. 그러나 동맥경화의 중요한 유발인자로 알려진 HDL-cholesterol^24)은 별다른 변화가 관찰되지 못하였다. 결국 흰쥐에게 사염화탄소를 투여함으로써 혈청에서 지질함량과 동맥경화지수가 증가하였으며 이것은 동맥경화증과 관련된 혈관의 순환기 질환 발병의 위험성이 높아진 것이며 제조 수침액은 혈청 지질함량을 감소시킴으로써 이들 질환의 치료가능성이 있다고 할 수 있을 것이다. The purpose of this study was to investigate the effect of Holotrichia diomphalia Bates on serum lipid contents in carbon tetrachloride-treated The water extract of ones was obtained and administrated to rats. The results that lipid contents in serum were increased by intra peritoneal injection of carbon tetrachloride that of control group, but they were significantly decreased by orally administration of Holotrichia diomphalia Bates water extract. But HDL-cholesterol content was not changed and arteriosclcrotic index was increased almost twice in carbon tetrachloride-treated group than in normal group. Therefore, it syggested that Holotrichia diomphalia Bates could be promising agents in a circulatory disorder including arteriosclerosis.

관상동맥 스텐트 내 재협착의 발생에 미치는 임상적 관동맥 조영술적 요인들

윤혁준,김기식,박형섭,이영수,현대우,한성욱,허승호,김윤년,김권배,박남희,원경숙 대한순환기학회 2003 Korean Circulation Journal Vol.33 No.12

천연자원을 이용한 간기능 증진제 개발 연구 : Benzo(a) pyrene에 의해 유도된 간기능 장해에 미치는 세신 추출액의 영향 The Effect of Asiasari Radix on Benzo(a)pyrene Induced Hepatotoxicity

윤수홍,박은주,오관현 효성여자대학교 부설 한국환경위생연구소 1994 환경위생연구 Vol.4 No.1

Effect of Asiasari Radix, which is a herbal drug used frequently in the oriental prescriptions, water extract on the liver-protective activities were investigated in the rats. Asiasari Radix extract, when administered into the gast-ric intubation, produced liver-protective effect against benzo(a)pyrene induced liver damage. The results obtainedfrom liver microsomal enzyme assay, measurement of serm and liver alanine·aspartate aminotransferase and lipid accumulation, indicated that alismatis extract showed significant liver-protective activities agai-nst benzo(a) pyrene poisoning.

천연자원을 이용한 간기능 증진제 개발 연구 : Benzo(a)pyrene에 의해 유도된 간기능 장해에 미치는 천궁 추출액의 영향 The Effect of cnidii Rhizoma on Benzo(a)pyrene Induced Hepatotoxicity

윤수홍,이송애,하헌,박은주,오관현 효성여자대학교 부설 한국환경위생연구소 1993 환경위생연구 Vol.3 No.1

민간에서 주로 사용되는 약용식물들 중 간독성 의 발현 저해 및 간기능 보호 효과가 우수한약물을 찾아 임상적인 약효를 밝혀보고자 하는 실험과정으로 탄소화합물의 불완전 연소및 열분해에 의해 생성되는 간장해 물질인 benzo(a)pyrene으로 유도한 rats의 간독성발현에 미치는 천궁 수침액의 예방 및 치료 효과를 실험하여 다음과 같은 결과를 얻었다. 1. 천궁 수침액의 투여는 B(a)P 투여로 현저하게 증가된 혈청 및 간장의 AST, ALT,LDH, ALP 활성을 유의성 있게 감소시켰다. 2. B(a)P 투여로 증가한 혈청 total cholesterol 및 phospholipid 함량은 천궁 수침액의투여로 감소시킬 수 있었으나 그 효과는 현저하지 않았다. 3. 천궁의 투여는 B(a)P에 의한 간독성 발현을 유의성 있게 감소시켰으며 그 효과는전처리가 후처리에 비해 우수하였다. The present study was undertaken to compare the pharmacologicalactivity of crude Cnidii Rhizoma reported with the clinical uses in the orientalmedicine. Crude Cnidii Rhizoma used for the treatment of anemia, body chill,menstural irregularity and menstural pain as hematic, tonic effector, sedative,adodyne and clear extravasated blood. Therefore we tested the effects of Cnidii Rhizoma water extract on the liver-protective activities in the rats. The results obtained from liver microsomal enz-yme assay, measurement of serum and liver alanine, aspartate aminotransferaseand lipid accumulation indicated that Cnidii Rhizoma extract showed significantliver-protective activies against benzo(a)pyrene poisoning.

저마찰인공고관절전치환술의 X선학적 고찰

윤종섭,고재휴,김영용,곽현수 대한의학협회 1975 대한의학협회지 Vol.18 No.7

출력 피드백제어 시스템을 위한 적응 관측제어기

윤신용,백수현,김용 동국대학교 대학원 1999 大學院硏究論集-東國大學校 大學院 Vol.29 No.-

Adaptive control is one of the ideas conceived in the 1950's which has firmly remained in the mainstream of research activity with hundreds of papers., One of the reasons for the rapid growth and continuing popularity of adaptive control is its clearly defined goal : to control plants with unknown parameters. Adaptive control has been most successful for plant moduls in which the unknown parameters appear linearly. Adaptive backstopping and turning functions produces are Lyaunove-based design. A common approach to output feedback control of linear system is to use the certainty equivalence principle and combine state-feedback controller with the estimators (observers). In this paper we designed the modular of output feedback control system, the output feedback modular approach results in separation of two design modules : observer based scheme, swapping based scheme. We design output-feedback control laws which guarantee input-to-state stability with respect to the parameter error, its derivative, and the state estimation error as the inputs. The schemes in the paper are simpler than the tuning functions schemes because they do not eliminate angle error θ for the error system.

農家所得增大를 위한 보리쌀 消費增大方案에 관한 硏究 : 보리쌀 炊飯特性 硏究를 통한 보리 利用性 提高方案

尹水弘,徐挺植,金尙玉,玄仁煥 영남이공대학 1981 論文集 Vol.10 No.-

This study was carried out as a program to increase the utilization of barley by improving the acceptable eating quality of Korea's traditional cooked barley of a grain type. The barley's characteristics of cooking and acceptable eating quality according to its pearling rate by pearling it differently in the four classes; 70%, 60%, 50%. 45% (as the weight ratio of pearled barley to covered one) were examined extensively including the general compositions of samples, the time course changes of barley's volume and weight in proportion to the soaking before cooking, the experiments of the physiochemical characteristics (the water-uptake ratio and swelled volume of polished barley when cooked, the pII, iodine color intensity and total solids in the residual cooking liquid) and textural properties by the universal testing machine about the cooked barley as a objective testing method of acceptable eating qualities, the sensory evaluation of cooked barley as a subjective testing method of acceptable eating qualities, etc. The results were as follows: 1. According to the decrease of pearling rates, moisture contents and nitrogen-free extracts of samples were increased slightly, but their components of crude protein, crude lipid, crude fibre and ash were decreased greatly 2. In the time-course changes of the capacity of water-uptake and swelling of volume according to the soaking of samples before cooking, the increased weight ratios were increased in proportion to the decrease of pearling rate of barley, but the increased volume ratios were increased according to the order of covered barley, Akibare(rice), 50% pearled barley, 60% pearled barley, 70% pearled barley, 45% pearled, ane especially the volume increases were marked at the early stage of soaking in 70% pearled barley. 3. According to the decrease of pearling rate, water-uptake ratios during cooking were increased, but swelling of volume had the maximum value at 60% pearled barley, decreased again having the minimum value at 45% pearled barley. 4. pH values of the residual cooking liquid of the cooked barley were decreased according to the decrease of pearling rate and were considerably less than the pH, 6.46 of Akibare. The iodine color intensity and total solids of the residual cooking liquid of the cooked barley were increased greatly according to the decrease of pearling rate, but were considerably lower as compared with those of Akibare as a whole. 5. The texture profile of the cooked barley obtained by the universal testing machine were analyzed by the methods of Bourne. Henry etc. Max. force known to hardness, force to 20% compression, compressive gumminess, compressive chewiness were increased according to the order of pearling rate, 60%, 50%, 45%, 70% and recorded the higher values as compared with those of Akibare. Compressive cohesiveness, peak force, tensile hardness, tensile springiness, tensile cohesiveness, tensile gumminess, tensile chewiness were increased according to the decrease of pearling rate of barley and reached the maximum at 45% pearled barley, but recorded the much lower values as compared with those of Akibare. But springiness did not show some differences between the pearling rates or rice and barley polished. 6. According to the results of panel tests about the cooked barley by the hedonic scoring method based on a 5-point scale, color, tasts, appearance, adhesiveness, total acceptability had significant differences between samples at 95% level, but other quality factors did not and there were no significant differences between panel members. The means of total scores increased according to the order of pearling rate. 60%. 70%, 50%, 45%, and therefore it was shown that 45% pearled barley had the best acceptable eating quality.

Benzo(a) pyrene에 의해 유도된 간기능 장해에 미치는 시호와 황금의 병용 효과

尹水弘,吳官絃,朴銀珠 대구효성가톨릭대학교 1992 연구논문집 Vol.45 No.1

This study was attempt to evaluated the effect of Bupleuri Radix extract and Scutellariae Radix extract as the hepatotropic agents. In addition, we measured the relative effectiveness of drug combined treatment in comparison to that of alone treatment. The results are as follows ; 1. Serum and liver AST, ALT activities and liver bilirubin content of B(a)P treated group were significantly increased in comparison to normal group. After administration of Bupleuri Radix extract these enzyme activity and bilirubin content were decreased. 2. Scutellariae Radix extract decreased the increase of serum and liver AST, ALT, liver LDH activities and bilirubin content in B(a)) treated group. 3. After combined treatment of Bupleuri Radix and Scutellariae Radix extract, the serum and liver AST, ALT activities and liver bilirubin content were significantly decreased in comparison to that of drug alone treatment. 4. Buplerui Radix extract prevented the leakage of serum and liver total cholesterol, serum phospholipid and triglyceride levels caused by B(a)P treatment. 5. Scutellariae Radix extract prevented the leakage of serum and liver triglyceride and liver total cholesterol levels caused by B(a)P treatment. 6. After combined treatment of Bupleuri Radix and Scutellariae Radix extract, the lipid accumulation of serum and liver was significantly decreased in comparison to that of drug alone treatment. 7. The hepatotropic effect of drug extracts against B(a)P induced hepatotoxicity was superior to combined treatment of Bupleuri and Scutellariae Radix extract and after-treatment in comparison to that of alone treatment and pretreatment.

무정자증의 진단과 치료

尹賢洙 대한의사협회 1999 대한의사협회지 Vol.42 No.8