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Clinical Features of Generalized Granuloma Annulare in Korea
( Euy Hyun Chung ),( Sang Hoon Lee ),( Moon Kyun Cho ),( Jongs Uk Lee ),( Sung Yul Lee ) 대한피부과학회 2015 大韓皮膚科學會誌 Vol.53 No.2
Background: Generalized granuloma annulare (GGA) is a benign granulomatous disease of an unknown etiology. Although numerous studies about GGA have been reported, publications that describe the general clinical features of the disease are very sparse. Objective: This study aimed to identify the clinical characteristics of Korean GGA cases. Methods: We reviewed and analyzed the clinical data derived from four patients diagnosed with GGA at our hospital and the clinical data from 58 patients diagnosed with GGA at other Korean hospitals between 1995 and 2011. Results: The cutaneous lesions could be divided into the annular (n=30, 48%) and nonannular (n=32, 52%) types, and the lesions were more common in males than in females, with 33 males and 29 females affected. The GGA incidence showed a bimodal distribution with respect to age at disease onset. Twenty-six cases (42%) presented within the first decade of life and 29 cases (47%) presented when they were in the fifth decade of life or older. Twelve patients (19%) had systemic diseases. Of note, diabetes mellitus (DM) occurred only in adult GGA patients who were aged over 40 years. Conclusion: In contrast to previously reported studies, this study shows that the age at GGA onset has a bimodal distribution, and that GGA occurs more often in males. The prevalence of DM among GGA-affected individuals was higher than that found in the general Korean population. Therefore, a DM workup should be undertaken for GGA-affected patients who are over 40 years of age. (Korean J Dermatol 2015;53(2):127∼132)
P101 : Comparison of the Q-switched Nd:YAG and ruby lasers in treating semi-permanant make up
( Euy Hyun Chung ),( Hyun Ju Kim ),( Je Min An ),( Young Lip Park ),( Kyu Uang Whang ),( Sung Yul Lee ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2
Background: Lasers based on the principle of selective photothermolysis are now being used to remove semi-permanent make up with various outcomes. Choosing the right laser for the specific semi-make up color is necessary for successful outcome. Objectives: The purpose of this study was to compare the effect of Q-switched Nd:YAG laser and Q- switched Ruby laser irradiation on black color semi- permanent make up on rat skin. And, in order to set a guideline for the black color semi-permanent make. Methods: Six black artificial tattoos on rat skin were treated with two kinds of Q-switched lasers: a Medlite II Biomedical Q-switched Nd:YAG laser (1064nm, 20 nanoseconds, 2.0mm spot size, 6J/cm2) and Melastar Q-switched Ruby laser (694nm, 40 nanoseconds, 2.5mm spot size, 8-10 J/cm2). The authors used each lasers to irradiate pair of artificial tattoos on the same day of semi-permanent make up, 3 days after, 5 days after, 1 week after, 3 weeks after and 5 weeks after. Each artificial tattoos were irradiated 6 times. Then, checked the pigment level of laser irradiated sites with Mexameter® Pigmentation probe. And obtained the sample of tissue after 6 times irradiation. Results: Overall, the Q-switched Nd:YAG laser had a significant difference in semi-permanent make up lightening compared to the Q-switched ruby laser according to RMI and histopathological result. Conclusion: The Q-switched Nd:YAG laser was slightly superior to the Q-switched ruby laser on removing black semi-permanent make up.