일 전문대학 간호과 학생들이 인지하는 강의평가 기준에 대한 조사연구

김정애,이애경,주미경,정안순,장은정,김정수,강정희,이정애 경복대학 2004 京福論叢 Vol.8 No.-

일개 전문대학 간호과 학생들을 대상으로 강의평가 기준을 파악하고자 하였다. 개방형 질문지를 이용하였으며 7개의 교수관련 강의평가 문항 각각에 대해 좋은 점수 및 나쁜 점수를 부여하는 기준을 조사하였다. 각 문항별로 다양한 기준이 확인되었으며, 간호과 학생들의 강의 만족도를 높일 수 있는 교수설계를 위한 기초 자료로 활용할 수 있을 것이다. We aimed to set standards for the student evaluation of instruction for college students of Nursing. We used an open questionaire and surveyed the standards for how students judge the instruction good of bad by using seven questions related to the instructor. Various standards set from each question could be used as basic materials to meet the students' needs in the classroom when the instructors try to find out new instructional design.

임상실습 교육개선을 위한 간호학생의 간호활동시간 분석

이애경,김정애,주미경,정안순,장은정,김정수,강정희,이정애 경복대학 2001 京福論叢 Vol.5 No.-

신규간호사의 능력은 간호학생 때의 다양한 임상경험에 기초를 둔다. 따라서, 간호대학의 교수, 병원 지도자, 임상지도자는 간호학생들이 다양한 지식을 획득하고 간호기술을 경험할 수 있도록 도와주는 중요한 역할을 한다. 이 연구의 목적은 이러한 간호학생들의 임상실습에서 수행하는 간호활동과 간호활동 시간을 분석하고자 하는데 있다. 연구결과 간호학생 1인당 직접간호활동 시간은 185.5분(직접간호비율은 56.7%)으로 141.65분(간접간호 비율은 43.3%)인 간접간호활동 시간보다 많았다. 직접간호활동 시간 중 활력징후 측정이 51.9분으로 가장 많은 시간을 차지하였고, 간접간호활동 시간 중에는 차트보기가 22.98분으로 가장 많은 시간을 차지하였다. 전반적으로 기본적인 임상간호 수행기술에 소요되는 시간이 고도의 숙련된 간호기술을 수행하는데 드는 시간보다 많은 것으로 나타났다. 따라서, 본 연구결과를 토대로 간호대학의 지도자와 병원의 지도자 및 임상지도자가 함께 임상실습 교육과정의 지침서와 평가서를 평가할 필요가 있다고 제언하는 바이다. The competence of newly graduated nurses is based on various clinical experiences gained when they were students. Therefore, professors in nursing schools, directors in hospitals or preceptors must play a critical role in assisting them to obtain various knowledge and experienced nursing skills. The purpose of this study is to investigate nursing care activities and nursing care hours practiced by nursing students in clinical experience. The results of this study showed that the direct nursing care hours per each nursing student are 185.5 mins(direct nursing care rate 56.7%) and it is higher than indirect nursing care hours, 141.65 mins(indirect nursing care rate 43.3%). The hours of checking vital signs are the longest(51.9mins) among the direct nursing care activities, and the hours of reviewing chart are the longest(22.98mins) among the indirect nursing care activities. In general, the time of performing basic clinical nursing technique was higher than that of performing high skilled nursing technique. And nursing observation was higher than that of directly performing task. So, we suggest based on the results of this study as follows. It is needed for nursing instructors in nursing schools and hospitals together to evaluate the guidelines and check-list of clinical practice courses.

소화성 궤양 환자에 대한 염산 베넥세이트(울굿^(�)) 임상 효과

정현용,육은주,이헌영,노홍구,김영건 최신의학사 1993 最新醫學 Vol.36 No.8

정신질환의 유전학적 연구 : 정량적 유전학의 기본 개념과 방법론

주은정,김용식 대한신경정신의학회 2000 신경정신의학 Vol.39 No.2

정신질환에 유전적 요인이 관여함은 잘 알려진 사실이다. 정신질환에 관여하는 유전자를 규명하기 위해서는 정량적 유전학의 연구결과를 토대로 한 분자유전학적 연구들이 시행되어 질병에 관여하는 구체적인 유전적 돌연변이를 밝혀내는 것이 필요하다. 정량적 유전학은 유전 역학적 연구, 연관연구, 연합연구등의 분야로 나누어진다. 쌍생아 연구, 양자연구 및 가계내 재현위험도를 보는 유전 역학적 연구는 관심의 대상이 되는 표현형이 얼마나 유전적인지를 규명해 준다. 정량적 유전 분석은 재결합과 연관 현상에 기초하고 있다. 연관이란 충분히 가까운 거리에 위치하는 두 유전자 부위는 재결합이후에도 분리되지 않는 현상을 의미한다. 유전적으로 타당하게 정의된 표현형 자료 및 중합효소 연쇄반응을 통해 얻은 유전형 자료에 적합한 유전분석 통계기법을 적용하여 분석하는 것이 정량적 유전학 연구의 기본 방법이다. 가계 내에서 전체 염색체중 표현형과 연관을 보이는 염색체 부위를 분석해 내는 방법이 연관연구이며, 질병군 및 대조군을 비교하여 특정 후보유전자에 대한 연관 불균형을 관찰하는 방법이 연합연구이다. 연관연구는 크게 모수적인 방법과 비모수적인 방법으로 분류될 수 있고, 연합연구는 일반 인구집단을 대조군으로 하는 방법과 가족을 대조군으로 하는 방법으로 나누어 볼 수 있다. 부모의 유전형을 분석에 도입한 특수한 연합분석방법은 일반인구 집단을 대조군으로 하였을 때 우려되는 인구 층형성 문제를 해결하 고자 제안된 방법들이다. 지금까지의 연구결과 정신질환은 유전적인 요소가 강하나 멘델의 유전법칙을 따르지 않는 복합형질이며 아마도 여러 개의 유전인자가 복합적으로 질병발생에 영향을 미칠 것이라고 추정되고 있다. 복합형질의 난점을 해결하기 위한 동물모델 및 endophenotype의 개발과 이들을 이용한 QTL(quantitative Trait Loci) 연구, 신뢰성 있게 표준화된 대규모의 공동연구를 통해 지금까지 시행되어 온 연구들의 통계적인 한계를 극복하는 것이 향후의 연구방향이 되어야 한다. Quantitative medical genetics including genetic epidemiological studies, linkage studies, and association studies are the basis for molecular genetic studies to find the susceptible genes or responsible mutations for psychiatric disorders. Epidemiological studies on recurrence risk, twin studies and adoption studies have shown that genetic components are contributing for the development of psychiatric disorders. The basic concept of quantitative genetics is recombination and linkage phenomenon. Linkage is that two genetic loci located close enough to each other will not be separated after recombination in meiosis. Linkage analysis and association studies can be accomplished by appropriate genetic analysis methods with genetically well defined phenotype data and genotype data generated by PCR. Linkage analysis are focused on simultaneous transmission of genotype and phenotype in multiplex pedigrees. Linkage analysis could be divided into two categories : parametric and nonparametric methods. Association studies are designed to find linkage disequilibrium between candidate gene and disease phenotype. Family-based association study methods are recommended to exclude possible population stratification of population-based case control studies. In spite of lots of evidence supporting great genetic influence on psychiatric disorders, genetic studies on psychiatric disorders have not been easy. It is probably because psychiatric disorders are composed of complex traits which do not follow Mendelian inheritance and several genes may contribute to only a small proportion of variances in the trait. In order to solve this complexity, animan models and genetically proper endophenotypes should be developed and be applied to QTL (Quantitative Trait Loci) analysis. At the same time, statistically powerful sample size should be established through worldwide collaboration to overcome small gene effects of psychiatric disorders.

신경회로망을 이용한 이면비드 폭 예측에 관한 연구

정재원,김일수,박창언,김학형,서주환,김인주,심지연 한국공작기계학회 2008 한국공작기계학회 춘계학술대회논문집 Vol.2008 No.-

The development of robotic welding process is a very complex assignment because the system is affected by a number of process parameters which are very difficult to determine or predict in practice. The full automation welding has not yet been achieved partly because the mathematical model for the process parameters of a given welding task is not fully understood and quantified. Several mathematical models to control welding quality, Productivity, micro structure and weld properties in arc welding processed have been studied. However, it is not an easy task to apply them to the various practical situations because the relationship between the process parameters and the bead geometry is non-linear and also they are usually dependent on specific experimental result. Practically, it is difficult, but important to know how to establish a mathematical model that can predict the result of the actual welding process and how to select the optimum welding condition under a certain constraint. In this paper, an attempt has been made to develop an neural network model to predict the back-bead width as a function of key process parameters in the GMA (Gas Metal Arc) welding and to compare the developed models with the experimental results

한국인에서 NOTCH4 유전자 내 두 개의 단일염기다형성과 정신분열병의 연합연구

주은정,정성훈,김미재,구영진,배승오,안용민,이규영,김용식 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : Previous studies on N0TCH4 gene and schizophrenia have not produced consistent results, and more studies with various ethnicities and populations were warranted. This study was performed with Korean population to find the role of the N0TCH4 gene in the development of schizophrenia. Methods : 235 schizophrenics and 236 normal controls participated in the study. Two SNPs (-1725 A/G and -25 T/C) on the N0TCH4 gene were investigated. Genotyping was done by Taqman assay, and statistical analysis was done by contingency chi-square test for the allele and genotype frequencies and PowerMarker V3.0 for the haplotype. Results : The two SNPs did not deviate from Hardy-Weinberg equilibrium in neither schizophrenics or normal controls. Two groups were not different in terms of allele and genotype distribution for both SNPs. Two SNPs were found to be in linkage disequilibrium. Haplotype analysis could not find an association between schizophrenia and these two SNPs. There was no association between the age at onset and the genotypes for both SNPs. Conclusion : We could not find any significant association between schizophrenia and the N0TCH4 gene in this Korean population. Although there are limitations in this study, this result supports the conclusion that the N0TCH4 gene is less likely to play a major role on the development of schizophrenia in the Asian population.

앞태머의 분석화학적 응용

조은정,이주운 忠州大學校 2009 한국교통대학교 논문집 Vol.44 No.-

Aptamers are single stranded nucleic acids selected via innovative in vitro selection process with target specific and selective binding properties. Once the sequence of selected aptamer is identified, aptamers can be either chemically or enzymatically synthesized and engineered with various functional groups. The unique target recognition that can rival antibodies and the simple and flexible chemical preparation that is originated from organic synthesis have highlighted the advantages of aptamers to a broad range of analytical and therapeutic applications. In particular, the specific ligand binding characteristics derived the use of aptamers for target identification, such as seperation/purification, diagnostics, and biosensors. On the other hand, the simple chemical modification foster unlimited application of aptamers to wide variety of analytical platforms and also enhanced the drug potency. In this review, authors aim to emphasis the capability of aptamers as promising analytical tools and provide useful guidelines for further development.

정신분열별 유전연구의 난점과 해결방안

주은정 대한생물치료정신의학회 2001 생물치료정신의학 Vol.7 No.2

Previous genetic studies on schizophrenia has been failed to show any confirmatory results, even though it is clear that genetic factors are working substantially on developing schizophrenia. In this review the reasons of difficulties to reach consistent findings was searched at the aspect of phenotype definition and statistica methods as well as alternative methods possibly to overcome these difficulties. The common statistical problems are multiple testing, population stratification, improper study design or analytic methods, and small sample size. The problems associated with phenotype are vagueness of schizophrenic symptoms and no objective laboratory methods to diagnose schizophrenia. Alternative methods possibly to solve these problems are suggested. For statistical difficulties, p value or LOD score corrected for multiple testing, simulation studies, family based control association study, large scale association studies suing dense SNPs, nonparametric analysis, collaborative studies, meta-analysis are suggested. For phenotype difficulties, more objective standardized international instrument such as DIGS, clinical subtype, symptom itself as a phenotype, various trials to define diagnostic borderline, quantitative biological endophenotype, and animal model are considered. Recent rapid progress of molecular genetic technology and rapidly accumulating genetic information and development of more proper study design and statistical analysis for schizophrenia will make it possible to find susceptible genes for schizophrenia in nearest future.

장기간 보관한 멸균물품의 오염 상태에 관한 연구

주홍순,조순덕,정재심,신동분,임바올라,노은지,이선희,송영미,최정화,백병윤,김미나 대한병원감염관리학회 2003 의료관련감염관리 Vol.8 No.1

컬러 영상에서 문자 추출 및 잡음 제거

정장호,이은주 한밭대학교 산업과학기술연구소 2001 논문집 Vol.5 No.-

This paper proposed a new algorithm for extraction of the characters and removal of noises in color images with characters and pictures. Binarization for extraction of the characters was performed by revised threshold which had computed with color-relationship relative to the number of pixel in background and character candidates in input images. The threshold has been computed by the histogram of R, G, B in respect of the images, while background and character candidates of input images are divided by the above threshold. As it is possible that revised threshold can be dynamically decided by the quantity of the noises, and the character images are maintained and the noises are removed to the maximum. We think it is optimum threshold. In this study, we made the noise pattern table as a result of analysis in noise pattern included in the various color images aiming at removal of the noises from the images. Noises included in the images can figure out Distribution by way of the noise pattern table and pattern matching itself. And then this Distribution classified difficulty of noises included in the images into the three categories. As removal of noises in the images is processed through different procedure according to the its classified difficulties, time required for computation and process was reduced. As a result of recognition experiments in respect of extracted characters in color images by way of the proposed algorithm, we conformed that the proposed algorithm is useful in a sense that it obtained the recognition rate in general documents to the same level.