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        Effect of treadmill exercise on skeletal muscle autophagy in rats with obesity induced by a high-fat diet Do Keun Cho1

        ( Do Keun Cho ),( Dong Hun Choi ),( Joon Yong Cho ) 한국운동영양학회 2017 Physical Activity and Nutrition (Phys Act Nutr) Vol.21 No.3

        [Purpose] This study aimed to investigate the effects of treadmill exercise on body weight, blood biochemistry, and autophagy. [Methods] Triglyceride, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, insulin, and glucose levels were measured, the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) score was calculated, and the soleus muscle was analyzed for autophagy- related factors (Beclin-1, p62, LC3, Lamp- 2) in rats with obesity induced by a high-fat diet. Eight-week-old Sprague Dawley rats were fed a high-fat diet for 35 weeks and then subjected to 10 weeks of treadmill exercise. The experimental group was divided into a Normal Diet-Sedentary (ND-SED, n=8) group, an (High-Fat Diet-Sedentary (HF-SED, n=8) group, and an High-Fat Diet + Treadmill Exercise (HF-TE, n=8) group. The intensity of treadmill exercise was set as 8 m/min for 5 min, 11 m/min for 5 min, 15 m/min for 20 min, and 11 m/min for the last 5 minutes. A glucose tolerance test was performed at the 2nd and 8th week of exercise by sampling of tail blood. [Results] With endurance exercise, the HFTE group showed a significant decrease in body weight, with improved blood biochemical indices and HOMA-IR scores, in comparison with the HF-SED group. However, there was no significant difference in Beclin-1, p62, LC3, and Lamp-2 proteins as measured by autophagic flux in the soleus muscle. [Conclusion] Treadmill exercise induced improvements in body weight, body fat, and biochemical indicators of obesity and Type 2 diabetes, but had no effect on autophagy in soleus muscle.

      • 무용전공별 최대성 운동후 Endorphine변화 및 회복율에 관한 연구

        도정님,조근종 漢陽大學校 體育科學硏究所 1994 體育科學 Vol.14 No.14

        The purpose of this study was to investigate the endorphine secretion level of dancer according to operating conditions and the differences of catecholamine changes according to dance majors(korea dance,ballet,modern dance) following all-out running on treadmill to understand the physiological mechanism and emotional natural of dancer. Subjects for this study were total 15 female college students(each group : 5) on dance department of HS univ. in Seoul who were selec-ted by cluster sampling method. Independent variation for study was dance major and 5 conditions(rest, immediatly exercise, and IS, 30, 60min. after exorcise), dependent variation was endorphine. Exercise treatment protocol was Bruce's stress testing protocol. For data analysis used 2 way ANOVA of SPSS and critical level for significance was α 0.05. The result of study can be summarized as follows. 1, On endorphine, there are non significant differences among all groups on all conditions. 2. On endorphine recovery rate, korea dance group show the highest, modern dance group show the lowest significantly. 3. Endorphines according to 5 conditions, all groups showed significantly the lowest level at rest or 1 hour after exercise and the highest level at immediate exorcise. In summary, the results of this study showed that dance majors can't effected on endorphine changes in some conditions, but recovery rate are closely related to dance major. But all results have some problem to generalize because individual differences of subject, small subject, difference of equipment condition. So, in fu- ture research should be consider proper exercise treatment and research design ac- cording to subject's speciality.

      • SCIESCOPUSKCI등재
      • 운동 중 지방 대사에 대한 고찰

        이근일,백병주,김의영,김도준,조용철,정훈,조재혁 龍仁大學校 體育科學硏究所 2002 體育科學硏究論叢 Vol.12 No.1

        Glucose-fatty acid cycle is very important because it explains that fatty acid influences glucose level. Glucose-fatty acid cycle is the key factor to understand how endurance training which aids fat oxidation and carbohydrate stored in skeletal muscle influence mitochondria level. However, it is not certain whether glucose-fatty acid cycle influences exercising skeletal muscle of human being. As an energy resource, training increases use of fatty acid, endurance ability, and oxidation of triglyceride. During high level training, catecholamine secretions and restraint of fatty acid use caused by insulin increases dramatically, this results in reduction of free fat acids and reunification of free fat acids into triglyceride. Training restrains insulin activity and reduces plasma acid density, however, elite athletes have high triglyceride-fatty acid cycle. Although enzyme's activities and mitochondira's density increase after training, it's not certain that enzyme's activities is major factor in restraint of fatty acid oxidation in exercising muscle cells. Stores of fat leads to increases of fat oxidation, performance and reduces use of carbohydrate, however, there is no absolute evidence to support these results.

      • KCI등재

        이황화탄소 중독자들의 노출중단 이후의 심박동수 변이

        이상윤,조성일,백도명,변창범,김미정,박경근,임상혁,양길승,황창국,전형준 大韓産業醫學會 2006 대한직업환경의학회지 Vol.18 No.2

        목적: 2000년도에 이황화탄소 중독증 환자들과 대조군의 심박동수 변이를 비교하여 이황화탄소 중독증 환자들의 심박동수 변이가 대조군에 비해 유의하게 낮다는 연구보고가 있었다. 당시의 연구가 이황화탄소 노출이 중단된 상태에서 이황화탄소 중독자들의 건강 문제를 연구했다는 점에 의의가 있으나 연구 결과를 해석하는데 있어 제한점들이 있었다. 이 연구는 2000년도에 수행하였던 연구의 제한점을 극복하고 이황화탄소 노출이 중단된 이후의 이황화탄소 중독자들의 심혈관계 상태를 심박동수 변이를 이용하여 평가해보고자 하였다. 방법: 이황화탄소 중독증으로 진단받은 환자 122명과 환자군의 연령대와 성별 빈도에 따라 무작위 추출한 112명을 대조군으로 선정하였다. 자기 기입식 설문지와 건강검진을 통해 연령, 성별, 신장, 체중, 흡연, 음주, 규칙적 운동, 질병력, 직업력, 흉부 방사선 촬영, 심전도 측정을 실시하였다. 연구 대상자들은 의자에 앉힌 상태에서 5분 동안 심박동수 변이를 측정하였다. 이 연구에서 측정한 심박동수 변이 지표들은 정상 RR간격의 표준편차(standard deviation of all norma-to-normal intervals, SDNN), 인접한 RR간격들의 차이를 제곱의 합의 평균의 제곱근(square root of the mean of the sum of squares of differences between adjacent normal-to-normal intervals, RMSSD). 저주파영역(low frequency power, LF: 0.04~0.15Hz), 고주파 영역 (high frequency power, HF:0.15~0.4Hz), 전체 주파수 강도(total power, TP), 저주파/고주파 비 (LF/HF ratio)이다. 결과: 단변량 분석에서 이황화탄소 중독자들의 모든 심박동수 변이 지표들이 대조군에 비하여 낮았다. 다중선형회귀분석에서 이황화탄소 중독은 RMSSD를 유의하게 감소시키는 것으로 나타났다.(P<0.05). 결론: 이 연구는 이황화탄소 노출이 중단된 상태에서도 이황화탄소 중독자들에게 심혈관계와 관련된 건강문제가 있을 수 있음을 시사한다. Objectives: A previous study conducted in 2000 measuring the heart rate variability (HRV) of carbon disulfide (CS_(2))-poisoned subjected suggested that their HRV was reduced after exposure cessation. However, the study was limited by the following procedural limitations: (1) only 71 CS_(2)-poisoned subjects participated, (2) no females participated, and (3) the CS_(2)-poisoned subjects were older than the controls. This study was therefore conducted to overcome these limitations of the earlier study. Methods: The study subjects comprised 122 retired workers with CS_(2) poisoning and the same number of age- and sex-matched controls. Information on individual age, sex, height, wight, smoking history, alcohol drinking, regular exercise, medical and occupational history, chest x-ray, and ECG recording of the two groups was collected though a self-administered questionnaire and a medical examination. Standard Deviation of NN intervals (SDNN), Root-Mean-Square of Successive Differences (RMSSD), Total Power (TP), Low Frequency (LF), High Frequency (HF), and LF/HF ratio were measured as HRV indices for 5 minutes in the sitting position. Results: Univariate analysis revealed that all HRV indices of CS_(2)-poisoned subjected were lower than those of the controls. Multiple linear regression analysis showed that CS_(2) poisoning had negative association with all HRV indices and that its association with RMSSD was statistically significant(P<0.05). Conclusions: This study suggests that CS_(2)-poisoned subjects continue to have reduced HRV, even though the exposure has ceased.

      • 유도 '되치기 본'의 개선 방안에 관한 연구

        김의환,김도준,김규수,김관현,김종달,최종삼,조용철,박순진,윤익선,안병근,정 훈,김미정,한성철 龍仁大學校 武道硏究所 1999 武道硏究所誌 Vol.10 No.1

        The purpose of this study was to reform practically a Korean Judo's Doechigi-Bon(Forms of Counterattack, judo's Gaeshi no Kata, Judo's Uradori no Kata, Judo's Gonosen no Kata) that was established in 1955 Korea, according to changing of techniques by Judo's modernization, in order to have Judo's carefulness and systematic diffusion. Reform procedure of Judo's Doechigi-Bon was 1st stage, Questionnaire survey 303 judokas, 2nd stage, Technical seminar by judo experts(12 judo professor) 4 times, 3rd stage, wording report for reform, 4rd stage, Discussion and judgement of Teaching and Judgement commission of Korean judo Association(KJA), 5th stage, Public hearing for reform in KJA, 6th stage, Report and decision of board of directors in KJA, 7th stage, public publication of Judo News(No.53) in KJA. Basic principle of reform of Judo's Doechigi-Bon were as table 1. Table 1. Basic principle of reform of Judo's Doechigi-Bon ------------------------------------------------------------------------------- Items Reformed Key Points of Judo's Doechigi-Bon ------------------------------------------------------------------------------- 1. Structure 1) Grand classification : Classified by 3 parts(1,2,3Gyo) 2)Medium classification : Te waza, Goshi waza, Ashi waza devided per each part(Gyo) 3)Sub-classification : Classified five techniques per each part(Gyo) 2. Contents 1) Selected established techniques as possible 2) Considered rationalty and overlapping of counterattack techniques 3. Decision of Conterattack techniques 1) Refered to results of Basic Questionnaire survey 2) Priority to decisions of Judo expert technical seminar -------------------------------------------------------------------------------- Reformed Korean Judo's Doechigi-Bon(Forms of Counterattack techniques-KJA, 1999) are as follows: 1. Gyo; ① Uki otoshi -> Uchi mata ② Harai goshi -> Harai goshi gaeshi ③ O soto gari -> O soto gake ④ Ko uchi gari -> Sasae tsurikomi ashi ⑤ O uchi gari -> Ko soto gari 2. Gyo; ① Ippon seoi nage -> Okuri eri jime ② Tsuri domi goshi -> Uki waza ③ Okuri ashi harai -> Okuri ashi harai ④ Ko soto gari -> Tai otoshi ⑤ Hiza guruma -> Hiza guruma 3. Gyo; ① Kata guruma -> Sumi gaeshi ② Tai otoshi -> Ko soto gari ③ Hane goshi -> Harai tsurikomi ashi ④ Uchi mata -> Tai otoshi ⑤ Tomoe nage -> O uchi gari

      • 스마트폰 부재와 분실을 대비한 어플리케이션

        조시현;문상수;김기환;도민균;서재현;김태공 인제대학교 2012 仁濟論叢 Vol.27 No.1

        Recently, as the Smart Phone is rapidly disseminated worldwide, it is emerging as an important digital communication media changing the communication types of users. We use the Smart Phone in all aspect of daily life besides communication. The Smart Phone is indispensible tool that has a great ripple effect on our daily life. Therefore, if the Smart Phone users lose or do not bring their phones, they were troubled. In this paper, we make users available to use the Smart Phone, even if they lose or do not bring their phones. To do this end, we develop features that search the phone in case of not knowing where it is, that contact another phone in case of not bringing their phone, that lock the phone in case of losing it. We expect these features promote a expansion and a vitality of the Smart Phone market.

      • KCI등재
      • KCI등재

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