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      • 비만증 환자에서 한약제에 의한 체중 감소효과

        Oh, Seung-Joon,Jeong, In-Kyung,Kim, Young-Seol,Choi, Young-Kil,Paeng, Jeong-Ryung,Bae, Jung-Hwan,Shin, Hyun-Dae 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

        Seung-Joon Oh, In-Kyung Jeong, Young-Seol Kim, Young-Kil Choi, Jeong-Ryung Paeng¹, Jung-Hwan Bae and Hyun-Dae Shin²Department of internal Medicine, College Medicine, Endocrine Research Institute¹. Department of Rehabilitation, College of Oriental Medicine², Seoul, korea. Bady Fat Reduction Effects of Red Ginseng Compound Preparation on the Patients with Obesity. Proceedings of International Symposium on East-West Medicine, Seoul. 244-254, 1999.-Obesity can be defined as a metabolic disease due to an increased state of fat tissues caused by an imbalance of calorie intake and use. Recently, in Korea by improvement and westernization of food intake, along with decrease in exercise activities, the prevalence of obesity has increased greatly. Our objectives were to study stability and effects of decrease in body fat by administering red ginseng compound preparation (known to have body fat decreasing effects in laboratory animals) to obesity patients on low calorie diets. Changes in weight and body fat were measured while carrying out calorie-restricted diets on patients for 4 weeks, then administering red ginseng compound preparation for another 4 weeks. The patients were 20 people whose BMI were 25kg/㎡ or over and whose percent body fat was also 30% or over when tested by bioelectrical conductivity. 1. Changes in weight were from 70.04kg(base line) to 67.43kg(after taking red ginseng compound preparation). 2. In similar sense, BMI decreased from 27.12kg/㎡(base line) to 26.56kg/㎡(after dieting), and further to 26.01kg/㎡ (after taking red ginseng compound preparation). The BMI seemed to decrease significantly compared to the baseline after the use of red ginseng compound. 3. Waist hip ratio was changed from 0.8858(base line) to 0.8728, but it was statistically insignificant. 4. The percent body fat was 35,16%(base line), 33.87%(after dieting), and 31.68%(after taking red ginseng compound preparation). 5. Complete blood cell count and blood chemisrty remained unaffected by the administration. 6. In concern to endocrinologic studies, T3 decreased from 118.7 to 98.2ng/dL, and T4 increased from 8.8 to 9.2㎕/ dL. Epinephrine showed a tendency to decreased from 0.27 to 0.25 ng/mL, and norepinephrine increased from 0.39 to 0.44ng/mL. 7. Leptin was not changed. 8. Some patients complained adverse effects; constipation(5 patients, may be due to diet therapy), fatigue (2 patients), pruritus(2 patients), flushing(s patients), dizziness(3 patients) and epigastric discomfort(2 patients). However their symptoms were mild, so medication did not stopped. In conclusion, loss of weight without significant side effects was observed during low calorie diet and red ginseng compound preparation administration. This is thought to be in relation to sympathetic nerve system rather than adrenal gland. Also, further long0term studies should be required, since the observed results were based on short-term changes in weight.

      • 랫드에서 신우황청심원의 급성 및 아급성독성시험

        오승민,남혜윤,김준수,연제덕,신대희,이진영,박대규,조명행,정규혁 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

        The acute and subacute toxicity of New Woohwangchungsimwon(NWCH) which was used l-muscone as substitutive material of musk were investigated in S.D. rats. In intraperitoneal acute toxicity test, rats(Sprague-Dawley, SPF) were injected intraperitoneally with dosages of 0, 540, 750, 1,070, 1,500 and 3,000 ㎎/㎏. Body weights were significantly decreased at 540 ㎎/㎏ dose group in both sexes and abnormal autopsy findings were founded in both sexes at all treated groups. Intraperitoneal LD_50 of NWCH was 812.3 ㎎/㎏ in male and 872.3 ㎎/㎏ in female rats. In the subacute toxicity study, NWCH was administrated orally to both sexes of rats for 4 weeks as several doses(0, 320, 800 and 2,000 ㎎/㎏). There were neither dead animals nor significant changes of body weights during the experimental period. In addition, no differences were found between control and treated groups in clinical signs, urinalysis, hematology, serum biochemical analysis, and other findings. Above data strongly suggest that no observed adverse effect level of NWCH might be over 2,000 ㎎/㎏/day in this study.

      • Toxoplasma 감염 가토의 임파구 아세포화 반응에 대한 연구

        오창진,이영하,나영언,신대환 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

        This study was performed to observe the differences of lymphocyte blastogienic responses in rabbits infected with Fukaya and Me49 strain of Toxoplasma gondii. Rabbits were subcutaneously inoculated with mouse brain emulsion containing 50 cysts of each strain of Toxoplasma gondii. A total of 9 male rabbits was used. From the 1st week after inoculation, blastogenic responses of peripheral blood lymphocytes treated with concanavalin A (Con. A, 10.0㎍/ml), lipopolysaccharide(LPS, 25.0㎍/ml) and Toxoplasma lysate(20.0㎍/ml) respectively were examined by [methyl-^3H]-thymidine incorporation assay at l week interval for 8 weeks. The results obtained in this study were as follows: 1. The blastogenic responses of the Con. A-treated and Toxoplasma lysate-treated lymphocytes from rabbits infected with Fukaya and Me49 strain of Toxoplasma gondii respectively were significantly declined as compared with those of the contol rabbits(p<0.05). No significantly differences were revealed in the blastogenic responses of the experimental group each other. 2. The blastogenic responses of the LPS-treated lymphocytes from rabbits infected with Fukaya and Me49 strain of Toxoplasma gondii respectively were not significantly declined as compared with those of the contol mice. No significantly differences were revealed in the blastogenic responses of the experimental group each other. The results suggested that there were no significantly differences in the blastogenic responses to Con. A, LPS and Toxoplasma lysate of each strain of Toxoplasma gondii infected rabbits. But the experimental group was a significant depression in blastogenic responses to Con. A and Toxoplasma lysate as compared with those of control group.

      • 동일한 혈관 내에 발생한 이식형 약제 주입기 카테터의 위치이상

        오대석,김영재,김명훈,조광래,임세훈,이정한,이근무,정순호,신치만 仁濟大學校 白病院 2010 仁濟醫學 Vol.31 No.-

        저자들은 56세 여성 환자의 왼쪽 쇄골 하 정맥에 시행한 이식형 약제주입기 카테터의 삽입 후 발생한 비정상 위치에 대한 증례를 보고하고자 한다. 카테터의 끝은 환자의 늘 어진 가슴, 체위, 신체의 움직임, 카테터의 유동성 등의 영향으로 천자된 정맥 내에서 견인되고 뒤쪽으로 이동하였다. 환자는 어떠한 증상도 호소하지 않았지만 비정상 위치의 카테터는 심각한 합병증을 유발할 수 있기 때문에 제거되었다. 따라서 시술자는 약제주입기 삽입 전에 환자의 신체 상태와 단순 흉부 촬영상을 확인하고 카테터의 비정상 위치가 발생할 수 있는 위험 징후를 알아차려야 하겠다.

      • 태권도 보수교육 참여자의 참여동기와 참여만족도의 관계

        오대영 慶熙大學校 社會體育硏究所 1998 體育科學論叢 Vol.- No.11

        This thesis is to study the motives of attendance and the satisfaction of the participants in the Taekwondo instructors' course as the 3rd class Sport for All qualification which aims at fostering Taekwondo instructors as professional sport for all instructors with systematic and variable education programs. Inquires were made to 3rd class sport for all instructors in Taekwondo having career of five years or longer who attended the Taekwondo Refresher Course for sport for all instructors in 1998. Appropriateness and the applicability of the draft enquete as well as its reliability and validity were examined through the preliminary test before the final enquete was made. Test sheets were distributed directly by the author and the trained assistant, who explained the purpose and the enquete and how to answer to the questions. The inquired were asked to answer in the self-administration method and the sheets were collected right after being filled out. Technical statistic analysis, ANCOVA, and MCA were made using Windows SPSS/PC+6.1 as a study tool. The following conclusions were made through such process and method: First, motives and satisfaction according to the demographic variables partially differ according to the Taekwondo instructor's income and career. Those with four million won or higher income ranked highest in both motives and satisfaction with the curriculum of the education. Motives and satisfaction according to Taekwondo career caused difference in satisfaction with the curriculum. That is, those with the shortest career showed the greatest satisfaction. Second, the effect of the motives to attend Taekwondo Refresher Course on his/her satisfaction differs partially: these who attended the course to obtain information showed higher satisfaction with instructors; those who attended the course to improve their quality as instructors showed higher satisfaction with the curriculum : and those who attended the course with a sense of duty showed higher satisfaction with the improvement of their Taekwondo instruction quality.

      • KCI등재
      • KCI등재

        비진료방문이 미취학 아동의 불안에 미치는 영향에 관한 연구

        오세영,김대업,이광희 大韓小兒齒科學會 1995 大韓小兒齒科學會誌 Vol.22 No.1

        The purpose of this study was to measure preschool children' anxiety about educational dental visit. This study was undertaken in 511 preschool children, 241 with educational dental visit and 270 without educational dental visit,whose age ranged from 3 to 7 years old. Preschool children during educational dental visit observated dental enviornment, directly touched dental instrument, and were surveyed oral condition. After they had gone to their preschool, they drew dentist. Drawings were analyzded using Human Figure Drawing Scoring System developed By Sonnenberg and Venham. The results were as follows ; 1. The anxiety score of group with educational dental vfisit was higher than that of group without dental visit(P<0.01). 2. The anxiety score was 9.28 in 4 year old, 6.78 in 5 year old, 4.79 in 6 year old, and 3.57 in 7 year old. There were significant difference in each groups(P<0.01). 3. The anxiety score of boys was higher than that of girls(P<0.05). 4. The anxiety score of untreated preschool children was higher than that of treated preschool children(P<0.01). 5. There was not the effect of relation between age and educational dental visit, between gender and educational dental visit, between treatment experience and educational dental visit(P<0.05).

      • KCI등재
      • 태권도 지도자들의 지도자 연수 프로그램 인식도에 관한 연구

        오대영,박준석,진중의 龍仁大學校 武道硏究所 1997 武道硏究所誌 Vol.8 No.2

        In this assertation I tried to investigate the disposition of what the Taekwondo masters think of the training programes for the Taekwondo masters and then tried also to study the direction of its advancement. The conclusions I obtained through the assertations are like the followings. First, for the most important reasons, the Taekwondo masters attend such training programes because it is necessary(40.9%), second for the development of himself(30.3%), third to help the educations on the next generation(26.8%). Second, they are satisfied with the facilities of training institute(56.1%) 26.8% feel inconvinient. Third, those who lecture in the training programes are sincere and feel that the training programes are helpful in the knowledge and skills. Forth, the exercise programes are the most helpful ones among all the training programes and the masters prefer the programes that are useful in actual situations. Thus, we can conclude that the current training programes are necessary for the trained, and it is required to found more facilities and various programes based on the enough investment.

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