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- 저자 : ( Dae Youb Baek ) (검색결과 3 건)
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A Case of Extralobar Bronchopulmonary Sequestration Similar form of SPN
( Dae Youb Baek ),( Yong Chul Lee ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1
Pulmonary arteriovenous malformation and Bronchopulmonary sequestration are rare disease of pulmonary vasculature. Pulmonary AV malformation are abnormal communications between pulmonary veins and arteries. Bronchopulmonary sequestration is a rare congenital malformation of the lower respiratory tract. It consists of a nonfunctioning mass of lung tissue that lacks normal communication with the tracheobronchial tree, and that receives its arterial blood supply from the systemic circulation. Symptoms of BPS can vary greatly, but they include a persistent dry cough. Complication of BPS include Hemorrhage, left-right shunt, chronic infection such as bronchiectasis, tuberculosis, aspergillosis. We here present an unusual case of Bronchopulmonary sequestration. A 60-year-old woman was admitted for evaluation of SPN. It was diagnosed at local clinic. CT scan was done during evaluation of rib fracture at local clinic. She had no known chronic disease. Local clinic’s HRCT finding was malignancy in lt. low lobe. So we performed lung cancer evaluation. PET-CT finding was lt. low lobe mass is less likely malignancy because there is no FDG-avidity. So enhanced Chest CT was done. And It’s finding was Probably AVM or AVF. For futher evaluation of lung mass, we performed thoracic Aortograpy. We could understand blood supply and venous return of lung mass using thoracic aortograpy. Aberrant artery from Aorta supply to lt. low lobe mass and then abnormal venous return was observed. So we could diagnosed Bronchopulmonary sequestration. We considered surgical resection but patient refused operation because she had no symptom. 5 Month later, Follow up HRCT was done and 2.2 cm sized mass had no interval change. We presented a case of Bronchopulmonary sequestration. Although it is rare congenital malformation of the lower respiratory tract. But during evaluation of SPN, we should concern the possibility of pulmonary vascular abnormality such as pulmonary arteriovenous malformation and bronchopulmonary sequestration. Because mostly there is no symptom in Bronchopulmonary sequestration patient, but rarely complications such as Hemorrhage, left-right shunt, chronic infection can occur in Bronchopulmonary sequestration.
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( Seon Ha Baek ),( Ran-hui Cha ),( Shin Wook Kang ),( Cheol Whee Park ),( Dae Ryong Cha ),( Sung Gyun Kim ),( Sun Ae Yoon ),( Sejoong Kim ),( Sang-youb Han ),( Jung Hwan Park ),( Jae Hyun Chang ),( Ch 대한내과학회 2019 The Korean Journal of Internal Medicine Vol.34 No.4
Background/Aims: Patients with chronic kidney disease (CKD) have been found to show markedly increased rates of end-stage renal disease, major adverse car diovascular and cerebrovascular events (MACCEs), and mortality. Therefore, new biomarkers are required for the early detection of such clinical outcomes in pa tients with CKD. We aimed to determine whether the level of circulating renalase was associated with CKD progression, MACCEs, and all-cause mortality, using data from a prospective randomized controlled study, Kremezin STudy Against Renal disease progression in Korea (K-STAR; NCT 00860431). Methods: A retrospective analysis of the K-STAR data was performed including 383 patients with CKD (mean age, 56.4 years; male/female, 252/131). We measured circulating renalase levels and examined the effects of these levels on clinical outcomes. Results: The mean level of serum renalase was 75.8 ± 34.8 μg/mL. In the multi variable analysis, lower hemoglobin levels, higher serum creatinine levels, and diabetes mellitus were significantly associated with a higher renalase levels. Over the course of a mean follow-up period of 56 months, 25 deaths and 61 MACCEs occurred. Among 322 patients in whom these outcomes were assessed, 137 adverse renal outcomes occurred after a mean follow-up period of 27.8 months. Each 10- μg/mL increase in serum renalase was associated with significantly greater haz ards of all-cause mortality and adverse renal outcomes (hazard ratio [HR] = 1.112, p = 0.049; HR = 1.052, p = 0.045). However, serum renalase level was not associated with the rate of MACCEs in patients with CKD. Conclusions: Our results indicated that circulating renalase might be a predictor of mortality and adverse renal outcomes in patients with CKD.
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