브로콜리 추출물의 향장활성 효과

김대용ㆍ조석철ㆍ권혁선ㆍ김미경(Dae Young KimㆍSeok chul ChoㆍHyuk sun KwonㆍMee Kyung Kim) 한국인체미용예술학회 2016 한국인체미용예술학회지 Vol.17 No.1

In this study, we investigated the anti-oxidative effects, antimicrobial, and anti-inflammatory activities of the extracts from broccoli to evaluate its use as a functional ingredient in cosmetics. The extracts are WE (water extract at RT), MWE (mineral water extract at RT), EE (70% ethanol extract at RT), and USEE (heat process for 12 hours at 60℃ after ultrasonification for six hours with 70% ethanol). The measurements of the total polyphenol content from broccoli extracts were highest in EE at 425.24±13.9 mg/g dry. The result of electron donating ability of EE was the highest at 10,000 ㎍/㎖ as 97.81% and increased in a concentration-dependent manner. The ferric reducing antioxidant powder (FRAP) of EE was the highest at 10,000 ㎍/㎖ as 1235.6 μM. In an antimicrobial activity test, the EE showed significant antimicrobial activity against S. epidermidis, S. aureus, E. coli, P. acnes, and P. ovale. Furthermore, broccoli extract exhibited no cytotoxicity in RAW 264.7 cells. Also anti- inflammatory activity by NO assay showed LPS-induced NO was significantly inhibited following treatment with EE of 1,000 ㎍/㎖. Therefore, the broccoli ethanol extract can be used as a resource of natural cosmetic material for functional cosmetics.

벡터기반 주파수 예약 알고리듬

김대수,장혁수 明知大學校 産業技術硏究所 2000 産業技術硏究所論文集 Vol.19 No.-

핸드오프가 빈번히 발생하는 마이크로 셀룰러 시스템에서 제한된 주파수 자원을 보다 효율적으로 사용하고자 하는 알고리듬들이 제안되어 왔으나 핸드오프를 위해 사용자의 실제 이동 방향에 관계없이 주위 셀 모두의 핸드오프 용 주파수를 예약하는 방식이 주로 사용되었고 그것은 주파수 자원의 낭비를 초래하여 왔다. 본 논문은 사용자의 이동 방향 및 속도가 고려된 벡터 파라미터를 사용하여 실제 이동 방향과 관계 있는 셀에 대해서만 핸드오프 용 주파수를 예약하는 방식을 제안하고 성능분석을 통하여 주파수 자원을 절약할 수 있음을 보여준다.

기업물류경쟁력확보를 위한 물류용기 풀시스템 도입성과 분석

김대기,김상철,김정혁 한국로지스틱스학회 2002 로지스틱스연구 Vol.10 No.1

본 연구의 목적은 물류용기 풀시스템 도입효과에 대한 이론적이고도 계량적인 근거를 제시함으로써 기존의 물류용기 사용 관행에서 오는 낭비요인을 찾아 제거하고, 이를 통해 물류표준화 및 공동화의 필요성을 강조하고자 함에 있다. 물류용기표준화 및 공동화의 도입효과를 분석하기 위하여, 국내의 한 완성 차 업계의 실 데이터를 이용한 Box Pool System 시뮬레이션 모델을 구축하였다. 평균 상차시간, box 보유량, 평균 box 체류시간 등의 성과척도를 중심으로 BPS도입효과를 분석한 결과, 평균 상차시간은 62%, 시스템 내 box 체류시간은 38% 감소하였으며, 기존의 약 1/3수준의 box보유만으로도 시스템을 효율적으로 운영할 수 있다는 긍정적인 결론을 도출하였다. 즉, 물류용기 표준화 및 공동화 작업은 물류비용절감과 물류서비스 개선을 통한 기업물류경쟁력 확보의 가장 기초적이고도 필수적인 조건이다. The purpose of the study is to provide theoretical and qualitative grounds to the introduction of container pool system. By finding our and eliminating wastes from our everyday routine practices, we emphasize the importance of joint utilization and standardization of containers. In order to qualitatively measure the effects of joint utilization and standardization of containers, we constructed BPS : 62% reduction in average loading time, 38% reduction in system queue time, and 68% reduction in box inventories in the system. That is, standardization and joint utilization of containers is the most fundamental and requisite condition to secure business logistics competitiveness, which is realized by logistics cost reduction as well as logistics service improvement.

광섬유를 이용한 고감도 압력센서의 개발

김창원,권대혁,김진섭,이정희,손병기 경북대학교 센서기술연구소 1995 연차보고서 Vol.1995 No.-

KOH 수용액을 이용하여 실리콘 식각공정기술을 확립하였으며, 이를 이용하여 실리콘 기판 위에 스트레스 균형이 이루어진 150 ㎚-Si_3N_4/300 ㎚-SiO_2/150 ㎚-Si_3N_4 두께를 가지는 구조의 평탄한 3층 유전체 멤브레인을 제작하였다. 본 실험에서 사용되는 파장인 1.3 ㎛ 근방에서 다이아프레임의 광투과도는 약 50 %로 광반사막으로 사용이 불가능하였다. 따라서, 다이아프레임 뒷면에 약 1000 Å의 금을 증착하여 N/O/N/Au박막의 광투과도를 수 %정도로 감소시킴으로써, 센서의 광반사막으로 사용할 수 있었다. source fiber를 단일모드로 했을 때 다이아프레임의 크기에 따라 감도는 각각 0.52㎻/torr(3×3 ㎟), 0.65 ㎻/torr(4×4 ㎟), 0.77 ㎻/torr(5×5 ㎟)였다. 광손실을 최소화하기 위해 광전송용 다모드 광섬유를 사용하였을 때는, 2×2 ㎟의 다이아프레임의 크기에 대해 0∼800 torr의 넓은 측정범위에서 거의 선형적인 압력특성을 나타내었다. Using KOH solution, silicon etching technology has been established and stress-balanced flat 600 ㎚ thick triple dielectric membrane(150 ㎚-Si_3N_4/300 ㎚-SiO_2/150 ㎚-Si_3N_4) on silicon substrate has been fabricated. At the wavelength of the sensor light source near 1.3 ㎛, the optical transmittance of the diaphragm was about 50 %, it was impossible to be used as a reflecting film. To decrease to a few percents, the back-side of the diaphragm was deposited 1,000 Å thick gold layer, which is sufficient enough to be used as a light reflection layer of the sensor. When was used 8/126 ㎛ single-mode fiber, the respective sensitivities for diaphragm size were 0.52 ㎻/torr(3×3 ㎟), 0.65 ㎻/torr(4×4 ㎟), 0.77 ㎻/torr(5×5 ㎟). When was used 62/126 ㎛ multi-mode fiber for the light transmission to minimize optical loss, the pressure characteristics was showed almost linearly curve in a wide pressure range, 0 torr∼800 torr, for the 2×2 ㎟ diaphragm in dimensions.

Diethyl 1-chloro-2-phenyl-2-(tosyl) aminoethylphosphonate 의 결정 및 분자구조

김대영,이재혁,신준철,김문집 순천향대학교 기초과학연구소 1997 순천향자연과학연구 논문집 Vol.3 No.1

The crystal and molecular structure of diethyl 1-chloro-2-phenyl-2-(tosyl)aminoethyl phosphonate has been determined from single crystal X-ray diffraction study ; C19H25NO5PCIS, Monoclinic, P2₁/a, a=10.8507(11)Å, b=16.1201(12)Å, c=12.7354(12)Å, β=90.192(7)°, V=2227.6(3)ų, T=293(2)K, Z=4, Cuk α(λ=1.54178Å). The structure was solved by direct method and refined by full-matrix least squares to a final R=5.17% for 2444 unique observed F0> 4σ(F0) reflections and 254 parameters.

인트라넷에서 멀티미디어 생방송 서비스를 제공하기 위한 효율적인 멀티캐스트 알고리즘

김대수,장혁수 명지대학교 산업기술연구소 2001 産業技術硏究所論文集 Vol.20 No.-

Many of the multicast applications such as video broadcasts and teleconferencing need to support dynamic multicast sessions wherein the membership of the multicast group changes with time. Most existing multicast servers require layer 3 or layer 4 switches to support dynamic multicast sessions, thou호 the switches are not affordable to the small and medium size organizations such as colleges. In this paper, we propose and algorithm to provide live multimedia service without the switches.

재발한 지주막하 포도낭미충증의 Albendazole 치험 1예

김성범,박대원,이재갑,정혜원,송준영,손장욱,김민자,박승철,제보경,김정혁,이진수 대한감염학회 2003 감염과 화학요법 Vol.35 No.5

뇌실이나 뇌기조에 발생하는 포도낭미충증은 매우 드물며 유구조충 유충의 머리부분이 변성되면서 발생하는 낭성 막의 비정상적인 성장을 특징으로 한다. 이러한 유형의 병변은 지름술 후에도 진행적인 경과를 보이며 아직까지 항기생충제를 이용한 치료 사례들이 적고, 따라서 가장 적절한 치료 기간도 알려져 있지 않다. 본 증례 보고는 재발한 실비우스 틈새의 포도낭미충증 환자에서 4주간의 albendazole과 스테로이드로 효과적으로 치료하였던 예이다. 환자는 praziquantel과 뇌복막지름술로 치료를 받고도 포도상의 뇌실질외형의 병변이 악화되어, 뇌척수액 투과가 좋은 것으로 알려진 albendazole로 치료제를 바꾼 뒤 병변의 수와 크기가 감소였으며 이후 2년 간의 추척기간동안 다른 발작 없이 잘 지내고 있다. 지주막하의 포도낭미충증은 albendazole과 corticosteroid 치료에 잘 반응하는 것으로 보인다. The so-called racemose cysticercosis, a rare variety of neurocysticercosis occurring in ventricles or basal cisterns, is characterized by abnormal growth of cystic membranes with degeneration of Taenia solium heads (scolex). Although lesions of this type are known to follow a progressive course even after ventricular shunting, there are limitations of case series treated with antiparasitic drugs, and the optimal duration of the treatment is not yet known. We report a case of relapsed racemose cysticercosis in the Sylvian fissure, who has been successfully treated with albendazole and adjunct corticosteroid for 4 weeks. The patient had been previously treated with praziquantel and ventricul-operitoneal shunt, and maintained on the anticonvulsant drug for one year, but returned to the hospital due to seizure recurrence. The patient has been well in seizure-free state for the follow-up 2 years after albendazole therapy. The subarachnoid racemose cysticercosis seems to respond well to treatment of corticosteroid along with prolonged albendazole.

자궁외 임신의 임상적 고찰

김대중,박성훈,정혁 조선대학교 부설 의학연구소 2000 The Medical Journal of Chosun University Vol.25 No.1

Background : This study is a clinical evaluation and statistical analysis on the cases of ectopic pregnancies who were surgically treated and histopathologically confirmed at the department of obstetrics and gynecology at Chosun university from January, 1995 to October, 1999. Results : 1. The hospital incidence of ectopic pregnancy was 1 in 10 deliveries and the most frequently age group was in 30~34 years of ages(33.3%). 2. Nulligravida was in 22.2% and the percentage of cases who had 1, 2, and 3 or more artificial abortion were in 30.0%, 19.8%, and 28.0% respectively and nullipara was in 35.4% and the percentage of cases who had 1, 2, and 3 or more deliveries were in 26.3%, 24.7%, and 13.6% respectively. 3. A previous history of appendectomy was in 12.3% and other abdominal surgeries were in 17.4%, pelvic inflammatory disease in 5.8%. 4. On symptomatology skipped menses was observed in 87.2%, lower abdominal pain in 86.0%, and bloody vainal discharge in 60.9%. 5. The mean duration from the first day of the last menstrual period to the date of operation was about 7 weeks. 6. The urine pregnancy test was positive in 75.5% and culdocentesis in 94.2%, Average serum β -hCG(human chorionic gonadotropin) level was about 3,200mIU/mL. 7. The most common site of ectopic pregnancy was salpinx in 91.7%. In the cases of tubal pregnancy, the lesion was most commonly located at the ampulla portion(82.3%) and ruptured tubal pregnancies were in 54.3%. 8. The amount of intraperitoneal free blood was 101~500ml in 29.2%, 501~1000mL in 31.3% and 1001~2000mL in 26.4%.91. Other abnormal pelvic conditions were noted in 30.5% and adhesion was in 13.6%. 10. The operative procedures were salpingectomy in 80.7%, salpingo-oophorectomy in 6.5%, corneal resection in 6.2%, and were laparoscopic operation in 24.3%, laparotomy in 75.7%. 11. There was no fatal case in 243 ectopic pregnancy.

요소 및 포도당 동시 측정용 ISFET다기능 바이오센서

김창수,권대혁,손병기 경북대학교 센서기술연구소 1990 센서技術學術大會論文集 Vol.1 No.1

A multi-biosensor for simultaneous detection of urea and glucose was fabricated by using ISFETs and Immobilized enzyme membrane and its performance characteristics were investigated. Detection of urea and glucose was possible in urea concentration range of 1~100mg/dl and glucose concentration range of 5~100mg/dl respectively. The ISFET multi-biosensor with strong advantages, very small size and fast response, showed high Potentials for in-situ measurements.

PDA 밸브에 의한 연소실내의 연소특성에 관한 연구

김대열,한영출,조재명,김양술,주신혁,박병완 한국공작기계학회 2003 한국공작기계학회 추계학술대회논문집 Vol.2003 No.-

An experimental study presents characteristics of combustion in a combustion chamber by port deactivation valve for economy and emissions standards. In order to use combustion properties data, it is necessary to build some data base, which use cylinder pressure sensor, etc. Port deactivation valve has been developed to satisfy requirement of achieving sufficient swirl generation to improve the combustion. A feasibility and necessity of combustion pressure based cylinder spark timing control has been examined. So, this was obtained the Coefficient of Variation(COV) and the mass-burned(MFB). The characteristics of pressure ratio fraction is similar to that of mass-burned fraction. Using the results of the test, the effects of the combustion chamber can be improved combustion stability by port deactivation.