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      저자 : ( D. Sh Saidkhanova ) (검색결과 1 건)
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      • Activated Sorbent Hemosorption at Patients with Liver Failure

        ( D. Sh Saidkhanova ),( B. A Saidkhanov ),( Kh. G Khalikulov ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

        Aims: In the last decade extracorporal hemosorption is successfully applied to elimination of pathological changes after liver operations complications. Methods: The hemosorption method is applied at 22 patients with liver failure caused by biliary tract obturation and purulent cholangitis. At the same time at 14 patients hepatogenic encephalopathy was noted with heavy endogenic intoxication. After washing of a sorbent without preliminary geparinization of the patient the highway of a fence was connected to a vein. Results: The effectiveness of a hemosorption was estimated on clinical manifestations and data of laboratory analyses which were defined prior to the procedure, after 1 and 2 sessions of a hemosorption. Clinically at all patients after 1 session of a hemosorption significant improvement of a state with decrease of symptoms of intoxication of an organism is noted. The effectiveness of holding a procedure the sorbent modified by a neutral anolyte was much higher, than an unmodified analog. The clearance of toxiferous metabolites and main markers of endogenic intoxication was higher, than at patients of control group which the hemosorption was carried out by the same sorbent, but not activated solution of a neutral anolyte. After 2 sessions of a hemosorption at most of patients, along with a normalization of the studied biochemical indexes restitution of the immunologic status was noted. Conclusions: Thus, oxidizing modification of a sorbent allowed to increase effectiveness of treatment substantially at patients with liver failure.

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