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Ai Nakamura,Zhou Peichen,Yoshifumi Morita,Hirofumi Tanabe 제어로봇시스템학회 2021 제어로봇시스템학회 국제학술대회 논문집 Vol.2021 No.10
Applying an external force to a person’s hyperextended fingertip produces electrical activity of the extensor digitorum muscle even when the hand is not opened by the person. Based on this, a finger extensor facilitation technique has been developed for hemiplegic patients who cannot open the paralyzed hand by themselves. In this study, we developed a finger extensor facilitation training device named “iPARKO” that imitates this technique. We examined the factors that promote activities in the extensor digitorum muscle by conducting active training using iPARKO. Experiments were conducted on a healthy person and a hemiplegic person. It was found that active training using iPARKO leads to activities in the extensor digitorum muscle even in a hemiplegic person who cannot open their hand. In addition, it was found that a hemiplegic person can increase muscle activity by pressing their hand movement and utilizing electromyography biofeedback. The hand movement was clarified as follows: the hemiplegic person pressed the hand against the moving part of the device and pushed the fingertip further into it as a voluntary movement to increase the amount of muscle activity.
( Ai Nakamura ),( Ayako Tachifuji ),( Yasushi Matsufuji ),( Mitsuhiro Nakamura ) 한국폐기물자원순환학회(구 한국폐기물학회) 2015 한국폐기물자원순환학회 3RINCs초록집 Vol.2015 No.-
The recycling activity of wastes has been promoting recently in Japan, however the recycling rate of food wastes is 20.4% in 2012, which is lower than those of other wastes. This was attributed to the shortage of demands of recycling due to the unstable quality and supply of recycled product. To solve these problems, Tanimura et.al1) suggested the new back-up method that the composts made from food waste were used as the cover soil in landfill, to promote the stabilization of incineration ashes by microbial activities1), 2). In this study, the effect of the easily degradable organic matter (EDOM) content in composts for the stabilization of incineration ashes was compared by using test columns simulated landfill within the different composts of the EDOM content. This was due to the incineration ashes contained little nutrient for the growth of microorganisms as well as microorganisms. The results suggested that the compost containing rich EDOM content was more effective on the neutralization and enrichment of microorganisms which were part of the promotion processes for rehabilitation of landfill with incineration ashes mainly.
Food plants suitable for mass rearing of the coconut hispine beetle Brontispa longissima
Ai Yamashita,Amporn Winotai,Satoshi Nakamura,Keiji Takasu 충남대학교 농업과학연구소 2009 농업과학연구 Vol.36 No.1
The invasive pest Brontispa longissima(Coleoptera: Chrysomelidae), native to Indonesia and Papua New Guinea, has extended its distribution to Australia, Asia and Pacific islands and caused serious leaf damages of the coconut palm Cocos nuciferain the invaded regions. Although biological control using parasitic wasps has successfully reduced population density and leaf damage levels, this pest and its natural enemies have not been efficiently producedin conventional methods using young leaves of C. nucifera. In the present study, we examined suitability of plants easily available in Thailand and Japan for mass rearing of this pest to develop effective mass rearing system of this pest. Mature, green leaves of the palms were also suitable for immature development and adult reproduction of this pest. Since mature leaves of C. nucifera are more abundant and less contaminated with fungus than the unopened leaf buds, mature leaves could be a promising plant diet for mass rearing of B. longissima. Ornamental palms such as Hyophorbe lagenicaulis and Washingtonia filifera were also suitable for immature development and reproduction of B. longissima. Away from palms, the cattail Typha spp. can sustain immature development and adult reproduction of B. longissima. In the area where C. nucifera is rare or not available, W. filifera or Typha spp. would be good food plants for mass rearing of this pest.
Food plants suitable for mass rearing of the coconut hispine beetle Brontispa longissima
Yamashita, Ai,Winotai, Amporn,Nakamura, Satoshi,Takasu, Keiji Institute of Agricultural Science 2009 Korean Journal of Agricultural Science Vol.36 No.1
The invasive pest Brontispa longissima(Coleoptera: Chrysomelidae), native to Indonesia and Papua New Guinea, has extended its distribution to Australia, Asia and Pacific islands and caused serious leaf damages of the coconut palm Cocos nuciferain the invaded regions. Although biological control using parasitic wasps has successfully reduced population density and leaf damage levels, this pest and its natural enemies have not been efficiently producedin conventional methods using young leaves of C. nucifera. In the present study, we examined suitability of plants easily available in Thailand and Japan for mass rearing of this pest to develop effective mass rearing system of this pest. Mature, green leaves of the palms were also suitable for immature development and adult reproduction of this pest. Since mature leaves of C. nucifera are more abundant and less contaminated with fungus than the unopened leaf buds, mature leaves could be a promising plant diet for mass rearing of B. longissima. Ornamental palms such as Hyophorbe lagenicaulis and Washingtonia filifera were also suitable for immature development and reproduction of B. longissima. Away from palms, the cattail Typha spp. can sustain immature development and adult reproduction of B. longissima. In the area where C. nucifera is rare or not available, W. filifera or Typha spp. would be good food plants for mass rearing of this pest.
Integrative analysis reveals early epigenetic alterations in high-grade serous ovarian carcinomas
Machino Hidenori,Dozen Ai,Konaka Mariko,Komatsu Masaaki,Nakamura Kohei,Ikawa Noriko,Shozu Kanto,Asada Ken,Kaneko Syuzo,Yoshida Hiroshi,Kato Tomoyasu,Nakayama Kentaro,Saloura Vassiliki,Kyo Satoru,Hamam 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
High-grade serous ovarian carcinoma (HGSOC) is the most lethal gynecological malignancy. To date, the profiles of gene mutations and copy number alterations in HGSOC have been well characterized. However, the patterns of epigenetic alterations and transcription factor dysregulation in HGSOC have not yet been fully elucidated. In this study, we performed integrative omics analyses of a series of stepwise HGSOC model cells originating from human fallopian tube secretory epithelial cells (HFTSECs) to investigate early epigenetic alterations in HGSOC tumorigenesis. Assay for transposase-accessible chromatin using sequencing (ATAC-seq), chromatin immunoprecipitation sequencing (ChIP-seq), and RNA sequencing (RNA-seq) methods were used to analyze HGSOC samples. Additionally, protein expression changes in target genes were confirmed using normal HFTSECs, serous tubal intraepithelial carcinomas (STICs), and HGSOC tissues. Transcription factor motif analysis revealed that the DNA-binding activity of the AP-1 complex and GATA family proteins was dysregulated during early tumorigenesis. The protein expression levels of JUN and FOSL2 were increased, and those of GATA6 and DAB2 were decreased in STIC lesions, which were associated with epithelial-mesenchymal transition (EMT) and proteasome downregulation. The genomic region around the FRA16D site, containing a cadherin cluster region, was epigenetically suppressed by oncogenic signaling. Proteasome inhibition caused the upregulation of chemokine genes, which may facilitate immune evasion during HGSOC tumorigenesis. Importantly, MEK inhibitor treatment reversed these oncogenic alterations, indicating its clinical effectiveness in a subgroup of patients with HGSOC. This result suggests that MEK inhibitor therapy may be an effective treatment option for chemotherapy-resistant HGSOC.
Physical Properties of a New Ternary Compound RP₃Al<SUB>5</SUB> (R = rare earth)
Hiroto Fukuda,Takatsugu Koizumi,Yoshiki J. Sato,Yusei Shimizu,Ai Nakamura,Dexin Li,Yoshiya Homma,Atsushi Miyake,Dai Aoki,Masashi Tokunaga,Ryoma Kato,Masanobu Shiga,Tatsuya Kawae,Fuminori Honda 한국물리학회 2023 새물리 Vol.73 No.12
Electronic properties of a new ternary f-electron system RP ₃Al<SUB>5</SUB> (R: rare earth elements) have been investigated. RPt ₃Al<SUB>5</SUB> crystalizes in the CePt ₃Al<SUB>5</SUB>-type orthorhombic structure where R atoms form 1-dimensional chains along the b-axis. LaPt ₃Al<SUB>5</SUB> shows superconductivity below 0.4 K, while others show magnetic ordering. CePt ₃Al<SUB>5</SUB> orders antiferromagnetically below T<SUB>N</SUB> = 1.2 K with spontaneous moment and shows successive magnetic transition at T<SUB>m</SUB> = 0.9 K. The nearly divalent antiferromagnet EuPt ₃Al<SUB>5</SUB> indicates an unusual valence cross-over behavior into the nearly trivalent state under high pressure of 9 GPa. It is also found that most of RPt ₃Al<SUB>5</SUB> orders antiferromagnetically and, in some cases, shows characteristic features in magnetic suscep- tibility, where the broad maximum appears slightly above T<SUB>N</SUB>, reecting the low-dimensional nature.
Anomalous Hall Effect in Rare Earth Antiferromagnets with the Hexagonal Structures
Yoshichika ?nuki,Kenri Nakaima,Wataru Iha,Shinya Matsuda,Masato Hedo,Takao Nakama,Dai Aoki,Ai Nakamura,Miho Nakashima,Yasushi Amako,Tetsuya Takeuchi,Tatsuma D. Matsuda 한국물리학회 2023 새물리 Vol.73 No.12
We measured Hall resistivities in nine antiferromagnets with the AlB<SUB>2-</SUB> and ZrNiAl-types hexagonal structures and found characteristic magnetic phases especially in ErGa₂ and HoAgGe.