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      • Ethnic Giving Versus Mainstream Giving by Foreign-Born Korean Immigrants in California

        Moon, Seong-gin,Choi, Sang Ok SAGE Publications 2013 Nonprofit and voluntary sector quarterly Vol.42 No.4

        <P>Based on a large-scale philanthropic survey conducted in California, this paper empirically examines the determinants of <I>ethnic giving</I> versus <I>mainstream giving</I> practices and the interactive relationships between the two observed among foreign-born Korean immigrants. The results of our bivariate probit regression analysis suggest several interesting findings. First, acculturation serves significant functions in immigrants’ decisions to give to mainstream organizations, but does not appear to affect ethnic giving decisions as profoundly. Second, U.S. educational experiences and gender are strong predictors of mainstream giving practices, whereas household incomes and religiosity figure significantly in terms of explaining ethnic giving practices. Additionally, citizenship is related weakly to ethnic giving practices. Finally, two distinctive giving practices are negatively interrelated, meaning that immigrants who donate to ethnic organizations are less likely to give to mainstream organizations, and vice versa.</P>

      • Contextual synchronization for efficient social collaborations in enterprise computing: A case study on TweetPulse

        SAGE Publications 2013 Concurrent engineering Vol.21 No.3

        <P>It is important to be aware of user contexts for supporting efficient collaborations among them. The goal of this article is to present a social collaboration platform where we can understand (1) how the user contexts are dynamically changing over time and (2) how the user contexts are mixed with multiple sub-contexts together. Therefore, we have implemented TweetPulse, which is a Twitter-based tool for context monitoring and propagation system in a given social network. TweetPulse can match contexts of the users (and integrate them) to find the most relevant users. Eventually, collaborations among users are <I>contextually synchronized</I> by dynamically organizing a number of communities. A set of users in each community can share their skills and core competencies with each other. We have shown the experimental results collected from a collaborative information searching system in terms of (1) setting thresholds, (2) searching performance, and (3) robustness testing.</P>

      • Experimental study on the effect of blade angle on regenerative pump performance

        Choi, Won Chul,Yoo, Il Su,Park, Mu Ryong,Chung, Myung Kyoon SAGE Publications 2013 Proceedings of the Institution of Mechanical Engin Vol.227 No.5

        <P>The regenerative pump is a kind of turbomachine that is capable of developing a high pressure rise at relatively low flow rates compared to the centrifugal and axial pumps. Although the efficiency of regenerative pumps is much lower than other turbomachines, they have still been widely used in many industrial applications for high heads at low flow rates. There are a few theoretical models to analyze the performance of regenerative pumps, though, the effect of the blade angle has not been included in any analysis model to date. In this study, the influence of the impeller blade angle and its shape on regenerative pump performance has been experimentally investigated. Straight blades with inclined blade angles of 0°, ± 15°, ± 30° and ± 45° were tested. In addition radial chevron impellers with chevron angles of 15°, 30° and 45° were also included in the present experiments. Hence a total of 10 blade configurations were examined. The pressure head, efficiency and the fluid temperature rise were measured at different flow rates and the results were expressed in appropriate non-dimensional coefficients. From the experimental results, it was found that the pressure head and the efficiency strongly depend on the blade angles as well as the blade geometry. Among all blade configurations tested in this study, the chevron blade exhibited the highest head with reasonably good efficiency. The comparative study shows that there is an optimum chevron angle of around 30° that yields the best performance. These experimental data may be used to include the effect of blade angles in the current performance analysis and design models to widen their applicability.</P>

      • Myasthenia Mimicking Monocular Elevation Deficiency

        Kee, Changwon,Cha, Dong Min,Ahn, Jeeyun,Hwang, Jeong-Min SAGE Publications 2013 Journal of child neurology Vol.28 No.1

        <P>Monocular elevation deficiency is the inability to elevate the eye in abduction and adduction. Myasthenia gravis could mimic any pattern of ophthalmoplegia. However, myasthenia gravis mimicking monocular elevation deficiency appears to be very rare. A 12-month-old girl presented with the inability to elevate the left eye and blepharoptosis from 3 months of age. A neostigmine test showed a weakly positive response. Repetitive stimulation of the left orbicularis oculi produced no decremental response. Three assays for acetylcholine receptor antibodies were negative. Placing ice over the lids definitely improved left blepharoptosis. In conclusion, myasthenia gravis could mimic elevation deficiency. An ice test could be very helpful in making the diagnosis. Myasthenia gravis should be included in the differential diagnosis of monocular elevation deficiency even at a young age.</P>

      • Chunggan extract (CGX), methionine-and choline-deficient (MCD) diet-induced hepatosteatosis and oxidative stress in C57BL/6 mice

        Park, H-J,Han, J-M,Kim, H-G,Choi, M-K,Lee, J-S,Lee, H-W,Son, C-G SAGE Publications 2013 Human & experimental toxicology Vol.32 No.12

        <P>In the present study, we aimed to evaluate the hepatoprotective and antioxidant effects of Chunggan extract (CGX) in an animal model of hepatosteatosis. The C57BL/6N mice were fed either methionine- and choline-sufficient (MCS) diet (<I>n </I>= 10) or a methionine- and choline-deficient (MCD) diet (<I>n </I>= 50) for 4 weeks, and then they were treated orally with CGX (100 or 200 mg/kg), ursodeoxycholic acid (80 mg/kg, as a positive control), or distilled water (DW, MCS diet group, and MCD diet group) for the final 2 weeks (once per day). The MCD diet induced severe hepatic injury with the typical features of hepatosteatosis in both serum and hepatic tissues. CGX treatment significantly attenuated these alterations in the serum levels including triglyceride (TG), aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, and total bilirubin. Moreover, CGX also efficiently prevented from the hepatic TG accumulation in the hepatic tissue, evidenced by histopathological findings, compared with the MCD diet. In addition, CGX treatment significantly ameliorated the excessive oxidative stress and antioxidant markers in the serum as well as the hepatic levels of reactive oxygen species, the levels of malondialdehyde, the protein carbonyl, and total antioxidant capacity, and the activities of superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase. In conclusion, our results indicate the experimental relevance of CGX for potential clinical application in patients with hepatosteatotic disorders and a possible mechanism related to its antioxidant properties.</P>

      • Cognitive impairment differs between neuromyelitis optica spectrum disorder and multiple sclerosis

        Kim, Su-Hyun,Kwak, Kichang,Jeong, In Hye,Hyun, Jae-Won,Jo, Hyo-Jin,Joung, AeRan,Yu, Eun-Seung,Kim, Ji-Hee,Lee, Sang Hyun,Yun, Sooin,Joo, Jungnam,Lee, Dong-kyun,Lee, Jong-Min,Kim, Ho Jin SAGE Publications 2016 Multiple sclerosis journal: clinical and laborator Vol.22 No.14

        <P>Conclusion: CI in patients with NMOSD may be not as common as in patients with MS. MS patients exhibited severe impairment, particularly on learning and memory tests, compared with NMOSD patients. Differential prevalence and patterns of CI between NMOSD and MS patients suggest that the two diseases have different mechanisms of brain injury.</P>

      • Backward inference and pruning for RDF change detection using RDBMS

        Im, Dong-Hyuk,Lee, Sang-Won,Kim, Hyoung-Joo SAGE Publications 2013 JOURNAL OF INFORMATION SCIENCE Vol.39 No.2

        <P>Recent studies on change detection for RDF data have focused on minimizing the delta size and, as a way to exploit the semantics of RDF models in reducing the delta size, the forward-chaining inferences have been widely employed. However, since the forward-chaining inferences should pre-compute the entire closure of the RDF model, the existing approaches are not scalable to large RDF data sets. In this paper, we propose a scalable change detection scheme for RDF data, which is based on backward-chaining inference and pruning. Our scheme, instead of pre-computing the full closure, computes only the necessary closure on the fly, thus achieving fast and scalable change detection. In addition, for any two RDF data input files to be compared, the delta obtained from our scheme is always equivalent to the one from the existing forward-chaining inferences. In addition, in order to handle RDF data sets too large to fit in the available RAM, we present an SQL-based implementation of our scheme. Our experimental results show that our scheme, in comparison to the existing schemes, can reduce the number of inference triples for RDF change detection by 10–60%.</P>

      • Selective detection of endotoxin using an impedance aptasensor with electrochemically deposited gold nanoparticles

        Su, Wenqiong,Kim, Sung-Eun,Cho, MiSuk,Nam, Jae-Do,Choe, Woo-Seok,Lee, Youngkwan SAGE Publications 2013 Innate immunity Vol.19 No.4

        <P>Using a single-stranded DNA (ssDNA) aptamer exhibiting high binding affinity (K<SUB>d</SUB> = 12 nM) to endotoxin as a probe, an impedance sensor where aptamer-conjugated gold nanoparticles (AuNPs) were electrochemically deposited on a gold electrode was fabricated and its performance in regard to endotoxin detection assessed. AuNPs have been employed widely as biosensors because of their unique physical and chemical properties. In order to maximize the performance of the impedance aptasensor on endotoxin detection, some critical factors affecting aptamer conjugation to AuNPs and target recognition ability (i.e. concentrations of aptamer coupled with AuNPs, pH, ion strength and cation effect at the time of aptamer–endotoxin interaction) were optimized. Electrochemical impendence spectroscopy, cyclic voltametry, atomic force microscope, scanning electron microscope and quartz crystal microbalance were employed to characterize all the modification/detection procedures during the sensor fabrication. The developed aptasensor showed a broad linear dynamic detection range (0.01–10.24 ng/ml) with a very low detection limit for endotoxin (0.005 ng/ml), despite the presence of several biomolecules (e.g. plasmid DNA, RNA, serum albumin, Glc and sucrose) known to interfere with other endotoxin assays. The demonstrated aptasensor required a detection time of only 10 min, providing a simple and fast analytical method to specifically detect endotoxin from complex biological liqors.</P>

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