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The Proteolytic Activity of Porphyromonas gingivalis Is Critical in a Murine Model of Periodontitis
Baek, Keum Jin,Choi, Yun Sik,Kang, Cheol Keun,Choi, Youngnim American Academy of Periodontology 2017 Journal of periodontology Vol.88 No.2
<P>Conclusion: The proteolytic activity of Pg was more critical than the cell invasion ability for inducing experimental periodontitis in mice, which could be attributed to the paracellular pathway dependence of gingival tissue invasion by bacteria in the mice.</P>
Lee, Chang-Kyun,Koo, Ki-Tae,Park, Yoon-Jeong,Lee, Jue-Yeon,Rhee, Sang-Hoon,Ku, Young,Rhyu, In-Chul,Chung, Chong-Pyoung American Academy of Periodontology 2012 Journal of periodontology Vol.83 No.1
<P>In previous studies, oligopeptide corresponding to the cell-binding domains of bone morphogenetic proteins that bind to bone morphogenetic protein receptor enhanced the bone regenerative capacity of bovine bone minerals (BBM). The aim of this study is to evaluate the ability of BBM coated with oligopeptide to promote periodontal regeneration in a 1-wall intrabony defect model in dogs.</P>
Choi, Yun S,Kim, Yong C,Ji, Suk,Choi, Youngnim American Academy of Periodontology 2014 Journal of periodontology Vol.85 No.8
<P>Many pathogens are known to modulate epithelial physical barriers, particularly tight-junction (TJ) proteins, to enter host cells and/or tissues. Growth factors have been implicated in the regulation of TJ proteins. The aim of this study is to determine differences in the levels of TJ proteins, growth factors, and their receptors in relation to bacterial invasion in diseased gingival tissues obtained from patients with periodontitis.</P>
Park, Eunjoo,Na, Hee Sam,Kim, Sheon Min,Wallet, Shannon,Cha, Seunghee,Chung, Jin American Academy of Periodontology 2014 Journal of periodontology Vol.85 No.6
<P>Xylitol is a well-known anticaries agent and has been used for the prevention and treatment of dental caries. In this study, the anti-inflammatory effects of xylitol are evaluated for possible use in the prevention and treatment of periodontal infections.</P>