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- 저자 : Yoan Lamarche (검색결과 1 건)
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Hadi Hariri,Stéphanie Tan,Patrick Martineau,Yoan Lamarche,Michel Carrier,Vincent Finnerty,Sébastien Authier,Francois Harel,Matthieu Pelletier-Galarneau 대한핵의학회 2019 핵의학 분자영상 Vol.53 No.4
Purpose FDG-PET/CT has the potential to play an important role in the diagnosis of sternal wound infections (SWI). The purpose of this study was to analyze the diagnostic accuracy of FDG-PET/CT for SWI in patients following sternotomy. Methods We performed a single-center, retrospective analysis of patients who had undergone median sternotomy and FDG-PET/ CT imaging. The gold standard consisted of positive bacterial culture and/or the presence of purulent material at surgery. Qualitative patterns of sternal FDG uptake, SUVmax, and associated CT findings were determined, and an imaging scoring system was developed. The diagnostic performances were studied in both the recent (≤ 6 months between sternotomy and imaging) and remote surgery phase (> 6 months). Results A total of 40 subjects were identified with 11 confirmed SWI cases. Consensus interpretation was associated with a sensitivity of 91%and specificity of 97%. Combination of uptake patterns yielded an AUC of 0.96 while use of SUVmax yielded an AUC of 0.82. Conclusions Results suggest that FDG-PET/CT may be useful for the diagnosis of SWI with optimal diagnostic accuracy achieved by identifying specific patterns of uptake. SUVmax can be helpful in assessing subjects with remote surgery, but its use is limited in the context of recent surgery. Further studies are required to confirm these results.
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