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False Information Diffusion in Public Crisis on Interpersonal Network and Intervention Strategies
Zhu Xiaoxia,Hao Jiajia,Hu Haiju 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.10
With the development of economy, the public crisis has been increasing frequently and false information took shape because of the public’s assentation and lack of recognition. The diffusion of false information has intensified the public panic and anxiety. Beside, it may cause secondary damage easily. Therefore, the management department of false information in public crisis information should control the diffusion of the false information quickly in order to reduce the loss. By the diffusion of the network of false information in public crisis based on the scale-free network (BA), this paper defines the nature of each social individual from the perspective of multi-agent. On the basis of these properties, this paper defines the individual opinion interaction rules when communicating. The research concludes that active individuals of information diffusion on interpersonal network are not the people with a great amount of friends, but the ones who have few friends. Nevertheless, the management department of false information in public crisis should maintain a circuitous neutral attitude rather than the “all-or nothing” coercive measures when intervene the diffusion process of the false information diffusion. Besides, the influencing social individuals are the “opinion leaders” who have a wide range of interpersonal communication.
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Lotus-Like Nano-Architectures Constructed from Self-Assembled Micelles via Hierarchical Assembly
Rongli Zhang,Xiaoxia Fan,Xiaofang Xu,Jingjing Lv,Zhenzhen Jin,Hui Hao,Cuige Zhang 한국고분자학회 2018 Macromolecular Research Vol.26 No.1
Dopamine modified γ-polyglutamic acid (γ-PGA-DA) copolymer and melamine (Mel) can self-assemble into Mel/γ-PGA-DA micelles via weak intermolecular interactions in aqueous solution containing small amount of methanol. When Mel/γ-PGA-DA micellar solution was cast on the surface of formvar stabilized with carbon support films, the lotus-like nano-architectures were formed on the surface of substrate via hierarchical assembly of micelles. The size of lotus-like nanoarchitectures was approximately 200 nm×500 nm. The possible driving forces for hierarchical assembly of micelles were the solution fluid and interaction between micelles. The hierarchical assembly of micelles was similar to the fractal aggregation of inorganic particles and a possible reason was discussed.
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Ten paths of PKA signaling pathway regulate hepatocyte proliferation in rat liver regeneration
Zhenchao Cheng,Lijuan Duan,Xiaoxia Hao,Zhanpeng Li,Gaiping Wang,Cunshuan Xu 한국유전학회 2012 Genes & Genomics Vol.34 No.4
Generally, protein kinase A (PKA) signaling pathway regulates many physiological activities such as cell proliferation and metabolism. However, little is known about how PKA signaling pathway composed of 16 paths participates in regulating hepatocyte proliferation during rat liver regeneration (LR). To explore the influence PKA signaling pathway upon hepatocytes at gene transcription level, Rat Genome 230 2.0 Array was used to detect expression changes of 225 related genes in isolated hepatocytes from rat regenerating livers, showing that 197 genes were contained in the array and 78 genes were significantly changed. Moreover, bioinformatics and systems biology methods were applied to analyze the precise role of PKA signaling pathway in regulating hepatocyte proliferation during LR, and it was found that 10 paths were related to hepatocyte proliferation during rat LR. In detail, 5 paths including SR→Gα-S→PKA, GPCR→Gα-S→PKA, GPCR→PLC→PKA, ET-1→PLC→PKA and hypoxia→AMP→PKA launched hepatocyte proliferation in initiating phase of LR,and then 3 paths including βR→Gα-S→PKA, GPCR→PLC→PKA and GPCR→Gβγ ┤AcⅤⅥ→PKA enhanced hepatocyte proliferation in progressing phase, whereas 3 paths including TGFB→SMAD3/4→PKA, CaCn→ACIX ┤PKA, SST→Gα-I ┤PKA inhibited hepatocyte proliferation in terminating phase of LR. In conclusion, 78 genes and 10 paths of PKA signaling pathway regulate hepatocyte proliferation in rat LR.
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