Soft Power of Seoul City - The Perceived Image of Seoul by Chinese Visitors

Jia Lin Wu,Bong Seok Kim People&Global Business Association 2017 Global Business and Finance Review Vol.22 No.3

Seoul is a popular destination for Chinese tourists and Seoul’s image has been a popular topic for scholars in recent years. This study aimed to examine Seoul’s largest consumers, Chinese visitors, and to obtain more understanding of these visitors’ perceptions of Seoul by analyzing Chinese visitors’ perceived image of Seoul and identifying the soft power of Seoul city. The study is based on 103 online photographic representations from 88 blogs identified through the well-known Chinese search engine-Baidu. The study found that Chinese visitors described Seoul as a modernized city with its own authentic culture, historical changes and accessibility. The soft power of Seoul is identified in several aspects, including cultural fascination, a safe environment, tourism attractiveness, and information accessibility. Marketers should take advantage of these soft powers to maintain the tourism industry. Synecdochical features should also be used to enhance the destination image of Seoul. In light of these results, the authors discuss implications for both marketers and researchers as well as directions for further research.

High Mobility Group Box 1 Protein Is Methylated and Transported to Cytoplasm in Clear Cell Renal Cell Carcinoma

Wu, Fei,Zhao, Zuo-Hui,Ding, Sen-Tai,Wu, Hai-Hu,Lu, Jia-Ju Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10

Background: The high mobility group box 1 (HMGB1) protein is a widespread nuclear protein present in most cell types. It typically locates in the nucleus and functions as a nuclear cofactor in transcription regulation. However, HMGB1 can also localize in the cytoplasm and be released into extracellular matrix, where it plays critical roles in carcinogenesis and inflammation. However, it remains elusive whether HMGB1 is relocated to cytoplasm in clear cell renal cell carcinoma (ccRCC). Methods: Nuclear and cytoplasmic proteins were extracted by different protocols from 20 ccRCC samples and corresponding adjacent renal tissues. Western blotting and immunohistochemistry were used to identify the expression of HMGB1 in ccRCC. To elucidate the potential mechanism of HMGB1 cytoplasmic translocation, HMGB1 proteins were enriched by immunoprecipitation and analyzed by mass spectrometry (MS). Results: The HMGB1 protein was overexpressed and partially localized in cytoplasm in ccRCC samples (12/20, 60%, p<0.05). Immunohistochemistry results indicated that ccRCC of high nuclear grade possess more HMGB1 relocation than those with low grade (p<0.05). Methylation of HMGB1 at lysine 112 in ccRCC was detected by MS. Bioinformatics analysis showed that post-translational modification might affect the binding ability to DNA and mediate its translocation. Conclusion: Relocation of HMGB1 to cytoplasm was confirmed in ccRCC. Methylation of HMGB1 at lysine 112 might the redistribution of this cofactor protein.

Bibliometric analysis of publications on inclusive education from the Web of Science Core Collection published from 1992 to 2020

Jia-Fen Wu,Xiaoxiao Lin 한국과학학술지편집인협의회 2021 Science Editing Vol.8 No.1

Purpose This study analyzed the bibliometric characteristics of publications on inclusive education in the Social Science Citation Index and Science Citation Index Expanded in the Web of Science Core Collection from 1992 to 2020. Methods Terms related to “inclusive education” and “inclusion of education” were used as keywords to search for journal articles on July 3, 2020. Results There were 1,786 articles, representing 3,376 authors, in the 345 journals scanned. The United States, United Kingdom, and Australia were the three leading countries/regions in this field. In the top 12 countries, the top 15 institutions and the top 10 most-cited journals were identified by either the number of publications or the number of total citations. Core themes from the 30 most highly-cited articles were teachers’ attitudes, teachers’ self-efficacy, and the effects of inclusive education. Teachers included both pre-service and in-service teachers; students represented those with and without special educational needs. Conclusion The results indicate that the United States, United Kingdom, and Australia dominated inclusive education research, originating most of the highly-cited articles, having more prolific authors, and presenting the most-cited institutions. Furthermore, three emerging core themes from the 30 most highly-cited articles were teachers’ attitudes, teachers’ self-efficacy, and the effects of inclusive education. Frontline teachers are recommended to submit manuscripts about their teaching experiences to the most-cited journals, which have a large readership. To measure the effects of inclusive education, it is essential to formulate reliable, valid, and culture-free research instruments for future studies.

Dynamic analysis of a beam subjected to an eccentric rolling disk

Wu, Jia-Jang Techno-Press 2013 Structural Engineering and Mechanics, An Int'l Jou Vol.47 No.4

This paper presents a theory concerning the beam element subjected to an eccentric rolling disk (or simply called the eccentric-disk-loaded beam element) such that the dynamic responses of a beam subjected to an eccentric rolling disk with its inertia force, Coriolis force and centrifugal force considered can be easily determined. To this end, the property matrices of an eccentric-disk-loaded beam element are firstly derived by means of the Lagrange's equations. Then, the overall property matrices of the entire vibrating system are determined by directly adding the property matrices of the eccentric-disk-loaded beam element to the overall ones of the entire beam itself. Finally, the Newmark direct integration method is used to solve the equations of motion for the dynamic responses of a beam subjected to an eccentric rolling disk. Some factors relating to the title problem, such as the eccentricity, radius and rotating speed of the rolling disk, and the Coriolis force and centrifugal force induced by the rolling disk are investigated. Numerical results reveal that the influence of last factors on the dynamic responses of the pinned-pinned beam is significant except the centrifugal force.

Partial Least Squares Based Gene Expression Analysis in EBV-Positive and EBV-Negative Posttransplant Lymphoproliferative Disorders

Wu, Sa,Zhang, Xin,Li, Zhi-Ming,Shi, Yan-Xia,Huang, Jia-Jia,Xia, Yi,Yang, Hang,Jiang, Wen-Qi Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11

Post-transplant lymphoproliferative disorder (PTLD) is a common complication of therapeutic immunosuppression after organ transplantation. Gene expression profile facilitates the identification of biological difference between Epstein-Barr virus (EBV) positive and negative PTLDs. Previous studies mainly implemented variance/regression analysis without considering unaccounted array specific factors. The aim of this study is to investigate the gene expression difference between EBV positive and negative PTLDs through partial least squares (PLS) based analysis. With a microarray data set from the Gene Expression Omnibus database, we performed PLS based analysis. We acquired 1188 differentially expressed genes. Pathway and Gene Ontology enrichment analysis identified significantly over-representation of dysregulated genes in immune response and cancer related biological processes. Network analysis identified three hub genes with degrees higher than 15, including CREBBP, ATXN1, and PML. Proteins encoded by CREBBP and PML have been reported to be interact with EBV before. Our findings shed light on expression distinction of EBV positive and negative PTLDs with the hope to offer theoretical support for future therapeutic study.

Improved snow ablation optimizer with heat transfer and condensation strategy for global optimization problem

Jia Heming,You Fangkai,Wu Di,Rao Honghua,Wu Hangqu,Abualigah Laith 한국CDE학회 2023 Journal of computational design and engineering Vol.10 No.6

The snow ablation optimizer (SAO) is a new metaheuristic algorithm proposed in April 2023. It simulates the phenomenon of snow sublimation and melting in nature and has a good optimization effect. The SAO proposes a new two-population mechanism. By introducing Brownian motion to simulate the random motion of gas molecules in space. However, as the temperature factor changes, most water molecules are converted into water vapor, which breaks the balance between exploration and exploitation, and reduces the optimization ability of the algorithm in the later stage. Especially in the face of high-dimensional problems, it is easy to fall into local optimal. In order to improve the efficiency of the algorithm, this paper proposes an improved snow ablation optimizer with heat transfer and condensation strategy (SAOHTC). Firstly, this article proposes a heat transfer strategy, which utilizes gas molecules to transfer heat from high to low temperatures and move their positions from low to high temperatures, causing individuals with lower fitness in the population to move towards individuals with higher fitness, thereby improving the optimization efficiency of the original algorithm. Secondly, a condensation strategy is proposed, which can transform water vapor into water by simulating condensation in nature, improve the deficiency of the original two-population mechanism, and improve the convergence speed. Finally, to verify the performance of SAOHTC, in this paper, two benchmark experiments of IEEE CEC2014 and IEEE CEC2017 and five engineering problems are used to test the superior performance of SAOHTC.

Comparison of Three Active-Frequency-Drift Islanding Detection Methods for Single-Phase Grid-Connected Inverters

Jia-rong Kan,Hui Jiang,Yu Tang,Dong-chun Wu,Yun-ya Wu,Jiang Wu 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.2

A novel islanding detection method is proposed in this paper. It is based on a frequency drooping PLL, which was presented in a previous work. The cause of errors in the non-detection zone (NDZ) of conventional frequency disturbance islanding detection methods (IDM) is analyzed. A frequency drooping phase-locked-loop (FD-PLL) is introduced into a single-phase grid-connected inverter (SPGCI), which can guarantee that grid current is in phase with the grid voltage. A novel FD-PLL IDM is proposed by improving this PLL. In order to verify the performance of the proposed FD-PLL IDM, a full performance comparison between the proposed IDM and typical existing active frequency drift IDMs is carried out, which includes both dynamic performance and steady performance. With the same NDZ, the total harmonic distortion of the grid-current in the dynamic process and steady state is analyzed. The proposed FD-PLL IDM, regardless of the dynamic or steady process, has the best power quality. Experimental and simulation results verify that the proposed FD-PLL IDM has excellent performance.

A Retrospective Study of the Effect of Spinopelvic Parameters on Fatty Infiltration in Paraspinal Muscles in Patients With Lumbar Spondylolisthesis

Jia-Chen Yang,Jia-Yu Chen,Yin Ding,Yong-Jie Yin,Zhi-Ping Huang,Xiu-Hua Wu,Zu-Cheng Huang,Yi-Kai Li,Qing-An Zhu 대한척추신경외과학회 2024 Neurospine Vol.21 No.1

Objective: The effect on fat infiltration (FI) of paraspinal muscles in degenerative lumbar spinal diseases has been demonstrated except for spinopelvic parameters. The present study is to identify the effect of spinopelvic parameters on FI of paraspinal muscle (PSM) and psoas major muscle (PMM) in patients with degenerative lumbar spondylolisthesis. Methods: A single-center, retrospective cross-sectional study of 160 patients with degenerative lumbar spondylolisthesis (DLS) and lumbar stenosis (LSS) who had lateral full-spine x-ray and lumbar spine magnetic resonance imaging was conducted. PSM and PMM FIs were defined as the ratio of fat to its muscle cross-sectional area. The FIs were compared among patients with different pelvic tilt (PT) and pelvic incidence (PI), respectively. Results: The PSM FI correlated significantly with pelvic parameters in DLS patients, but not in LSS patients. The PSM FI in pelvic retroversion (PT > 25°) was 0.54 ± 0.13, which was significantly higher in DLS patients than in normal pelvis (0.41 ± 0.14) and pelvic anteversion (PT < 5°) (0.34 ± 0.12). The PSM FI of DLS patients with large PI ( > 60°) was 0.50 ± 0.13, which was higher than those with small ( < 45°) and normal PI (0.37 ± 0.11 and 0.36 ± 0.13). However, the PSM FI of LSS patients didn’t change significantly with PT or PI. Moreover, the PMM FI was about 0.10–0.15, which was significantly lower than the PSM FI, and changed with PT and PI in a similar way of PSM FI with much less in magnitude. Conclusion: FI of the PSMs increased with greater pelvic retroversion or larger pelvic incidence in DLS patients, but not in LSS patients.

DAB Converter Based on Unified High-Frequency Bipolar Buck-Boost Theory for Low Current Stress

Jia-rong Kan,Yao-dong Yang,Yu Tang,Dong-chun Wu,Yun-ya Wu,Jiang Wu 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.2

This paper proposes a unified high-frequency bipolar buck-boost (UHFBB) control strategy for a dual-active-bridge (DAB), which is derived from the classical buck and boost DC/DC converter. It can achieve optimized current stress of the switches and soft switching in wider range. The UHFBB control strategy includes multi-control-variables, which can be achieved according to an algorithm derived from an accurate mathematical model. The design method for the parameters, such as the transformer turns ratio and the inductance, are shown. The current stress of the switches is analyzed for selecting an optimal inductor. The analysis is verified by the experimental results within a 500W prototype.

A Novel Effect of Lipids Extracted from Vernix Caseosa on Regulation of Filaggrin Expression in Human Epidermal Keratinocytes

( Wu Qiao ),( Tinghan Jia ),( Hongjian Gu ),( Ruihua Guo ),( Ken Kaku ),( Wenhui Wu ) 대한피부과학회 2019 Annals of Dermatology Vol.31 No.6

Background: Vernix caseosa (VC), which is known as a unique human substance, is a biofilm that covers the skin of most human newborns. VC has many biological functions including anti-infective, skin cleansing and skin barrier repair. Objective: In the study, we purpose to investigate the novel effect of lipids extracted from VC on the regulation of filaggrin (FLG) expression and anti-inflammation in normal human epidermal keratinocyte (NHEK) cells. Methods: The lipids were extracted by chloroform/methanol (Folch method) and the major properties of fatty acid methyl esters were determined with gas chromatography-mass spectrometer. The relative viability of NHEK cells was evaluated by Cell Counting Kit 8 assay. The related expression of skin barrier protein was accessed with real-time quantitative polymerase chain reaction, Western blot and Immunofluorescence in NHEK cells with or without poly (I:C). Meanwhile, the changes of thymic stromal lymphopoietin (TSLP) and tumor necrosis factor alpha (TNF-α) are analyzed by enzyme- linked immunosorbent assay. Results: VC lipids mostly contained saturated and branched chains fatty acids. The expression of mRNA and protein of FLG were significantly increased after the supplement with lipid in NHEK cells. Meanwhile, lipids reversed the inhibition of poly (I:C) on FLG. Moreover, lipids suppressed the over secretion of TSLP and TNF-α induced by poly (I:C). Conclusion: These results indicate that lipids extracted from VC has positive effects on the expression of FLG and anti-inflammation, suggesting that lipids of VC may be used for a reference for novel therapeutic method in reducing and remedying skin disease like atopic disease. (Ann Dermatol 31(6) 611∼620, 2019)