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      • The Socioeconomic Burden of Cancer in Member Countries of the Association of Southeast Asian Nations (ASEAN) - Stakeholder Meeting Report

        Jan, Stephen,Kimman, Merel,Kingston, David,Woodward, Mark Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.2

        The ACTION (Asean CosTs In ONcology) Study will be one of the largest observational studies of the burden of cancer ever conducted in Asia. The study will involve 10,000 newly diagnosed patients with cancer and will be carried out across eight low- and middle income countries within the ASEAN region (Indonesia, Thailand, Malaysia, Cambodia, Myanmar, Viet Nam, Laos and the Philippines). Patients will be interviewed three times over 12 months to assess their health, use of health care services, out of pocket costs related to their illness, social and quality of life issues. The project is a collaboration between the George Institute for Global Health, the ASEAN Foundation and Roche. The aim of the study is to assess the health and socioeconomic impact of cancer on patients in ASEAN communities, and the factors that may impact on these outcomes.

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        Adaptive plasticity of morphological and anatomical traits of Brant’s oak (Quercus brantii Lindl.) leaves under different climates and elevation gradients

        Soheili Forough,Heydari Mehdi,Woodward Stephen,Abdul-Hamid Hazandy,Naji Hamid Reza 한국산림과학회 2023 Forest Science And Technology Vol.19 No.2

        The morphological and anatomical characteristics of leaves are sensitive and adaptable to environmental changes. Determining eco-physiological patterns of leaf characteristics along elevational gradients allows for a better understanding and prediction of how plants might respond to climate change. In this work, the ecological adaptation mechanisms related to morphological and anatomical characteristics of Brant’s oak (Quercus brantii Lindl.) leaves were studied at three elevation classes (low, middle, and high) in two different Mediterranean and subhumid climates in Zagros forests in western Iran. There were no sig- nificant changes in leaf length, although the leaf-specific area was higher at low and middle elevations in subhumid climates. In addition, stomata length, width, density, and stomatal pore index were higher in the upper elevations of subhumid climate than in the Mediterranean climate. At low and middle elevations, dry matter content was higher at sites from the Mediterranean climate. The results of plasticity indices showed that individuals of Q. brantii from middle-elevation sites exhibited greater plasticity than those from low and high-elevation sites. Overall, Q. brantii, the dominant oak species in Zagros forests, appears to respond to elevational and environmental changes, suggesting that leaves can adapt to these changes through morphological and anatomical traits. These results provide new insights into the environmental adaptation strategies of plants at the morphological and anatomical levels against climate change.

      • The Burden of Cancer in Member Countries of the Association of Southeast Asian Nations (ASEAN)

        Kimman, Merel,Norman, Rosana,Jan, Stephen,Kingston, David,Woodward, Mark Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.2

        This paper presents the most recent data on cancer rates and the burden of cancer in the ASEAN region. Epidemiological data were sourced from GLOBOCAN 2008 and disability adjusted life years (DALYs) lost were estimated using the standard methodology developed within the World Health Organization's Global Burden of Disease study. Overall, it was estimated there were over 700,000 new cases of cancer and 500,000 cancer deaths in ASEAN in the year 2008, leading to approximately 7.5 million DALYs lost in one year. The most commonly diagnosed cancers were lung (98,143), breast (86,842) and liver cancers (74,777). The most common causes of cancer death were lung cancer (85,772), liver cancer (69,115) and colorectal cancer (44,280). The burden of cancer in terms of DALYs lost was highest in Laos, Viet Nam and Myanmar and lowest in Brunei, Singapore and the Philippines. Significant differences in the patterns of cancer from country to country were observed. Another key finding was the major impact played by population age distribution on cancer incidence and mortality. Cancer rates in ASEAN are expected to increase with ageing of populations and changes in lifestyles associated with economic development. Therefore, ASEAN member countries are strongly encouraged to put in place cancer-control health care policies, focussed on strengthening the health systems to cope with projected increases in cancer prevention, treatment and management needs.

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