해양 미세조류 Isochrysis galbana Parke로부터 EPA와 DHA의 생산

오유관(You-Kwan Oh),김유진(Yu-Jin Kim),박성훈(Sunghoon Park) 한국생물공학회 1997 KSBB Journal Vol.12 No.3

무인 자율주차 시스템 구현을 위한 기반기술 연구

전재한(Jaehan Jeon),최아라(Ara Choi),박성훈(Sunghoon Park),정태영(Taeyoung Chung) 한국자동차공학회 2014 한국자동차공학회 학술대회 및 전시회 Vol.2014 No.11

As an autonomous driving technology is the future of on-road driving, an unmanned valet parking system is one of a key technology to realize door to door autonomous vehicle. When an autonomous vehicle arrive its destination, the driver steps out of the car and pushes button on the smart phone, and then the vehicle autonomously parking in without any anxiety of user. Similarly, the vehicle gets out from the parking lot at right time and right position for user. We mainly focused on a vehicle actuator control, path following control for parking slot detection, parking maneuver control with shift-by-wire system, and smart phone interface between the user and vehicle. As the localization technology of a vehicle at the indoor or outdoor parking areas is most important and difficult problem, we applied precise position information from the DGPS for preliminary implementation of the system.

초음파 센서를 이용한 차량 주차공간 탐색에서의 연석 감지 알고리즘

김수용(Suyong Kim),이동욱(Dongwook Lee),박성훈(Sunghoon Park),권재희(Jaehee Kwon) 한국자동차공학회 2011 한국자동차공학회 학술대회 및 전시회 Vol.2011 No.11

Recently many automobile companies are developing parking assist system as it improves the convenience of drivers. Among several types of parking assistance system, the method using ultrasonic sensors for detecting parking space is widely used because of its low cost and usefulness. In order to detect the parking space, the parking space detection algorithm provides the width and the length of the parking space using long range ultrasonic sensor. In this paper, to detect the accurate parking space with the curbstone, the curbstone detection algorithm is proposed. The performances of the proposed algorithm are verified and evaluated by experiments.

In Vitro Antimicrobial Susceptibility of <i>Mycobacterium abscessus</i> in Korea

Park, Sunghoon,Kim, Shinok,Park, Eun Mi,Kim, Hojoong,Kwon, O Jung,Chang, Chulhun L.,Lew, Woo Jin,Park, Young Kil,Koh, Won-Jung The Korean Academy of Medical Sciences 2008 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.23 No.1

<P><I>Mycobacterium abscessus</I> is the second most common etiology of pulmonary disease caused by nontuberculous mycobacteria in Korea. Although antimicrobial susceptibility tests are important for appropriate patient management in <I>M. abscessus</I> lung disease, the tests have never been investigated in Korea. Seventy-four isolates of <I>M. abscessus</I> recovered from patient respiratory samples were tested against eight antimicrobial agents following the guidelines set forth by the National Committee for Clinical Laboratory Standards. Of the parenteral antibiotics, amikacin (99%, 73/74) and cefoxitin (99%, 73/74) were active against most isolates. Imipenem (55%, 36/66) and tobramycin (36%, 27/74) had activity against moderate number of isolates. Of the oral antibiotics, clarithromycin (91%, 67/74) was active against the majority of isolates. Moxifloxacin (73%, 54/74) and ciprofloxacin (57%, 42/74) had activity against a moderate number of isolates. Doxycycline was the least active, inhibiting only 7% (5/74) of isolates. In conclusion, the variations in susceptibility within <I>M. abscessus</I> isolates to currently available antimicrobials suggest that the antimicrobial susceptibilities of any clinically significant <I>M. abscessus</I> isolate be needed individually.</P>

A Multicenter Study of Pertussis Infection in Adults with Coughing in Korea: PCR-Based Study

Park, Sunghoon,Lee, Myung-Gu,Lee, Kwan Ho,Park, Yong Bum,Yoo, Kwang Ha,Park, Jeong-Woong,Kim, Changhwan,Lee, Yong Chul,Park, Jae Seuk,Kwon, Yong Soo,Seo, Ki-Hyun,Kim, Hui Jung,Kwak, Seung Min,Kim, Ju- The Korean Academy of Tuberculosis and Respiratory 2012 Tuberculosis and Respiratory Diseases Vol.73 No.5

Background: Limited data on the incidence and clinical characteristics of adult pertussis infections are available in Korea. Methods: Thirty-one hospitals and the Korean Centers for Disease Control and Prevention collaborated to investigate the incidence and clinical characteristics of pertussis infections among adults with a bothersome cough in non-outbreak, ordinary outpatient settings. Nasopharyngeal aspirates or nasopharyngeal swabs were collected for polymerase chain reaction (PCR) and culture tests. Results: The study enrolled 934 patients between September 2009 and April 2011. Five patients were diagnosed as confirmed cases, satisfying both clinical and laboratory criteria (five positive PCR and one concurrent positive culture). Among 607 patients with cough duration of at least 2 weeks, 504 satisfied the clinical criteria of the US Centers for Disease Control and Prevention (i.e., probable case). The clinical pertussis cases (i.e., both probable and confirmed cases) had a wide age distribution ($45.7{\pm}15.5$ years) and cough duration (median, 30 days; interquartile range, 18.0~50.0 days). In addition, sputum, rhinorrhea, and myalgia were less common and dyspnea was more common in the clinical cases, compared to the others (p=0.037, p=0.006, p=0.005, and p=0.030, respectively). Conclusion: The positive rate of pertussis infection may be low in non-outbreak, ordinary clinical settings if a PCR-based method is used. However, further prospective, well-designed, multicenter studies are needed.

Photoluminescence in MgO-ZnO Nanorods Enhanced by Hydrogen Plasma Treatment

Park, Sunghoon,Ko, Hyunsung,Mun, Youngho,Lee, Chongmu Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.11

MgO nanorods were fabricated by the thermal evaporation of $Mg_3N_2$. The influence of ZnO sheathing and hydrogen plasma exposure on the photoluminescence (PL) of the MgO nanorods was studied. PL measurements of the ZnO-sheathed MgO nanorods showed two main emission bands: the near band edge emission band centered at ~380 nm and the deep level emission band centered at ~590 nm both of which are characteristic of ZnO. The near band edge emission from the ZnO-sheathed MgO nanorods was enhanced with increasing the ZnO shell layer thickness. The near band edge emission from the ZnO-sheathed MgO nanorods appeared to be enhanced further by hydrogen plasma irradiation. The underlying mechanisms for the enhancement of the NBE emission from the MgO nanorods by ZnO sheathing and hydrogen plasma exposure are discussed.

High-response and selective hydrogen sensing properties of porous ZnO nanotubes

Sunghoon Park 한국물리학회 2016 Current Applied Physics Vol.16 No.10

Hydrogen gas is utilized in various industrial fields, and its utility in modern life is becoming a reality since the development of hydrogen fuel cell vehicles. However, hydrogen gas is extremely explosive at room temperature and requires cautious handling. Herein, a ZnO nanotube sensor was fabricated via a three step process; this sensor exhibited high response and selectively detected hydrogen gas owing to its large surface area and grain boundaries. The response of this sensor was quantified as 139.11 when 1000 ppm H2 gas was supplied to the sensor. A porous ZnO nanotube sensor was fabricated and the mechanism by which enhanced hydrogen sensing is achieved was evaluated.

Impact of Analgesic and Sedative Drugs on the Early Fluid Balance and In-hospital Mortality in Sepsis Patients

( Sunghoon Park ),( Kyeongman Jeon ),( Gee Young Suh ),( Young-jae Cho ),( Yeon Joo Lee ),( Sang-bum Hong ),( Dong Kyu Oh ),( Chae-man Lim ) 대한결핵 및 호흡기학회 2020 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.128 No.-

Background Despite some adverse effects, data on the use of analgesic and sedative drugs in patients with sepsis are very scarce. Methods Data from a prospective sepsis registry (by Korean Sepsis Alliance; 19 university hospitals; September 2019 to February 2020) were used in this study. We investigated impacts of the use of analgesic and sedative drugs (for the maintenance use) on fluid balance (during the first three days) and in-hospital mortality in both ventilated and non-ventilated sepsis patients. Results During the study period, a total of 899 patients (450 ventilated vs. 449 non-ventilated patients; septic shock, n = 369) were finally enrolled. Mean age was 69.7 ± 13.8 years and 514 patients were male. In ventilated patients, net fluid balance was higher in patients who received analgesics, sedatives, or neuromuscular blockers, respectively, compared to those who did not, but, neither of those drugs was associated with in-hospital mortality. However, among the nonventilated patients, those who received analgesics (n = 41) had a higher net fluid balance (3105.0 [1958.2 to 4679.5] ml vs.1957.2 [446.9 to 3487.8] ml, p = 0,001; Table 1) and a higher in-hospital mortality rate (18 [43.9%] vs. 79 [19.4%], p = 0.001), compared to those who did not. In multivariable analysis, after adjusting for covariates, the use of analgesic drugs (odds ratio, 4.28; 95% confidence interval, 1.336 to 13.709), compliance of 3-h sepsis bundle (0.326; 0.113 to 0942), and total net fluid balance (docile; 1.177; 1.020 to 1.358) were significantly associated with in-hospital mortality. Conclusions In this sepsis registry data, the use of analgesics not only increased net fluid balance, but also was independently associated with increased in-hospital mortality in nonventilated sepsis patients.

Room-Temperature Hydrogen Gas Sensing Properties of the Networked Cr2O3-Functionalized Nb2O5 Nanostructured Sensor

Sunghoon Park,Hyejoon Kheel,Gun-Joo Sun,Hyoun Woo Kim,Taegyung Ko,Chongmu Lee 대한금속·재료학회 2016 METALS AND MATERIALS International Vol.22 No.4

Cr2O3-functionalized Nb2O5 nanoparticles were synthesized via a facile hydrothermal route. The multiple-networked Cr2O3-functionalized Nb2O5 nanostructured sensor showed enhanced H2 gas sensing performance compared to its pristine Nb2O5 nanostructure counterpart. The Cr2O3-functionalized Nb2O5 nanostructure sensor showed responses of 5.24 to 2 ppm of H2 at room temperature, whereas the pristine Nb2O5 nanoparticle sensors showed responses of 2.29. The former also exhibited a faster response to H2. The multiple-networked pristine and Cr2O3-functionalized Nb2O5 nanostructured sensors were stronger and much shorter, respectively, than other nanomaterial-based Schottky diode-type sensors and Nb2O5-based Schottky diode-type sensors. The underlying mechanism for the enhanced sensing performance of the Cr2O3-functionalized Nb2O5 nanostructured sensor towards H2 gas is discussed in detail. Particular emphasis is placed on the role of the Cr2O3-Nb2O5 p-n junction in the Cr2O3-functionalized Nb2O5 nanostructure sensor.

Clinical significance of <i>Mycobacterium fortuitum</i> isolated from respiratory specimens

Park, Sunghoon,Suh, Gee Young,Chung, Man Pyo,Kim, Hojoong,Kwon, O. Jung,Lee, Kyung Soo,Lee, Nam Yong,Koh, Won-Jung Elsevier 2008 Respiratory medicine Vol.102 No.3

<P><B>Summary</B></P><P><B>Background</B></P><P>Although <I>Mycobacterium fortuitum</I> is not an uncommon organism among the non-tuberculous mycobacteria isolated from respiratory specimens, its clinical significance had not been well studied.</P><P><B>Methods</B></P><P>We identified all patients whose respiratory specimens were positive for <I>M. fortuitum</I> between January 2003 and December 2005. Among 182 patients whose specimens were positive for <I>M. fortuitum</I>, 26 were positive at least twice. We retrospectively reviewed their characteristics, and clinical courses.</P><P><B>Results</B></P><P>Of the 26 patients, 15 had two positive culture results for <I>M. fortuitum</I>; the other 11 had three or more. Sixteen patients were male and the median age was 61.5 years. Major presenting symptoms were cough (65%) and sputum (58%). Most patients had known underlying lung diseases, including prior tuberculosis (54%), lung cancer (15%), idiopathic pulmonary fibrosis (15%), and other mycobacterial lung disease (15%). The most common CT findings were bronchiectasis (80%). Only one patient received specific prolonged antibiotic therapy against <I>M. fortuitum</I> infection; the other 25 did not. No patients showed clinical aggravation during the follow-up period, although in five patients their underlying lung diseases continued to progress. The median follow-up duration was 12.5 months and none of the patients whose sputum specimens were available had persistent positive cultures for <I>M. fortuitum</I>.</P><P><B>Conclusion</B></P><P><I>M. fortuitum</I> usually causes colonization or transient infection in patients with underlying lung disease, such as prior tuberculosis or bronchiectasis. The majority of patients may not need to receive prolonged antibiotic therapy for <I>M. fortuitum</I> isolates.</P>