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      • Leukemia in Iran: Epidemiology and Morphology Trends

        Koohi, Fatemeh,salehiniya, Hamid,Shamlou, Reza,Eslami, Soheyla,Ghojogh, Ziyaeddin Mahery,Kor, Yones,Rafiemanesh, Hosein Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.17

        Background: Leukemia accounts for 8% of total cancer cases and involves all age groups with different prevalence and incidence rates in Iran and the entire world and causes a significant death toll and heavy expenses for diagnosis and treatment processes. This study was done to evaluate epidemiology and morphology of blood cancer during 2003-2008. Materials and Methods: This cross-sectional study was carried out based on re-analysis of the Cancer Registry Center report of the Health Deputy in Iran during a 6-year period (2003 - 2008). Statistical analysis for incidence time trends and morphology change percentage was performed with joinpoint regression analysis using the software Joinpoint Regression Program. Results: During the studied years a total of 18,353 hematopoietic and reticuloendothelial system cancers were recorded. Chi square test showed significant difference between sex and morphological types of blood cancer (P-value<0.001). Joinpoint analysis showed a significant increasing trend for the adjusted standard incidence rate (ASIR) for both sexes (P-value<0.05). Annual percent changes (APC) for women and men were 18.7 and 19.9, respectively. The most common morphological blood cancers were ALL, ALM, MM and CLL which accounted for 60% of total hematopoietic system cancers. Joinpoint analyze showed a significant decreasing trend for ALM in both sexes (P-value<0.05). Conclusions: Hematopoietic system cancers in Iran demonstrate an increasing trend for incidence rate and decreasing trend for ALL, ALM and CLL morphology.

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        Response modification factor of mixed structures

        Nader Fanaie,Shahab O. Shamlou 국제구조공학회 2015 Steel and Composite Structures, An International J Vol.19 No.6

        Mixed structures consist of two parts: a lower part and an upper part. The lower part is usually made of concrete while the upper part is made of steel. Analyzing these structures is complicated and code-based design of them has many associated problems. In this research, the seismic behavior of mixed structures which have reinforced concrete frames and shear walls in their lower storeys and steel frames with bracing in their upper storeys were studied. For this purpose, seventeen structures in three groups of 5, 9 and 15 storey structures with different numbers of concrete and steel storeys were designed. Static pushover analysis, linear dynamic analysis and incremental dynamic analysis (IDA) using 15 earthquake records were performed by OpenSees software. Seismic parameters such as period, response modification factor and ductility factor were then obtained for the mixed (hybrid) structures using more than 4600 nonlinear dynamic analysis and used in the regression analysis for achieving proper formula. Finally, some formulas, effective in designing such structures, are presented for the mentioned parameters. According to the results obtained from this research, the response modification factor values of mixed structures are lower compared to those of steel or concrete ones with the same heights. This fact might be due to the irregularities of stiffness, mass, etc., at different heights of the structure. It should be mentioned that for the first time, the performance and seismic response of such structures were studied against real earthquake accelerations using nonlinear dynamic analysis, andresponse modification factor was obtained by IDA.

      • Incidence and Mortality of Colorectal Cancer and Relationships with the Human Development Index across the World

        Rafiemanesh, Hosein,Mohammadian-Hafshejani, Abdollah,Ghoncheh, Mahshid,Sepehri, Zahra,Shamlou, Reza,Salehiniya, Hamid,Towhidi, Farhad,Makhsosi, Behnam Reza Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.5

        Background: This study aimed to investigate the standardized incidence and mortality rate of colorectal cancer and its relationship with the human development index (HDI) across the world in 2012. Materials and Methods: This ecologic study was conducted for assessment of the correlation between age-specific incidence rate (ASIR) and age-specific mortality rate (ASMR) with HDI and its components. Data for SIR and SMR for every country for the year 2012 were obtained from the global cancer project. We used a bivariate method for assessment of the correlation between SIR and SMR and HDI. Statistical significance was assumed at P<0.05. Statistical analyses were performed using SPSS (Version 22.0, SPSS Inc.). Results: Countries with the highest SIR of colorectal cancer in the world in 2012, were Republic of Korea, Slovakia, Hungary and countries with the highest SMR were Hungary, Croatia and Slovakia. The correlation between SIR of colorectal cancer and the HDI was 0.712 ($P{\leq}0.001$), with life expectancy at birth 0.513 ($P{\leq}0.001$), with mean years of schooling 0.641 ($P{\leq}0.001$) and with level of income per each person of the population 0.514 (P=0.013). In addition, the correlation between SMR of colorectal cancer and the HDI was 0.628 ($P{\leq}0.001$), with life expectancy at birth 0.469 ($P{\leq}0.001$), with mean years of schooling 0.592 ($P{\leq}0.001$) and with level of income per each person of the population 0.378 (P=0.013). Conclusions: The highest SIR and SMR of colorectal cancer was in the WHO Europe region. There was a positive correlation between HDI and SIR and SMR of colorectal cancer.

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