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      • Thyroid Cancer Epidemiology in Iran: a Time Trend Study

        Safavi, Ali,Azizi, Fereidoun,Jafari, Rozita,Chaibakhsh, Samira,Safavi, Amir Ali Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.1

        Background: Considering the rising incidence of thyroid cancer worldwide, the aim of our study was to investigate the temporal trends in the incidence of this cancer in a large population of Iranian patients. Materials and Methods: We used the Iran Cancer Data System (ICDS) Registry to assess the thyroid cancer trend from 2004 to 2010 with regard to different genders, age groups, and morphologies. To do this we analyzed the data of 10,913 new cases of thyroid cancer that occurred during these years. Results: The incidence rate (per one year) of thyroid cancer was 2.20 per 100,000 persons between 2004 and 2010 in Iran. Papillary thyroid cancer was the most common histology type, with an annual rate of 0.29 in Iran. The highest rate of prevalence in thyroid cancer was observed at the age of 45 years at the time of diagnosis. We found a female-to-male ratio of 2 in Iran. A significant decrease was detected in the trend of thyroid cancer in children <19y, which was not correlated to the trend of older patients. Conclusions: As expected, the trend of thyroid cancer increased over the 7 years, primarily contributed by papillary thyroid cancer. A rising pattern of incidence was seen in all the age groups except patients aged under 19 years.

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        Application of a new neutronics/thermal-hydraulics coupled code for steady state analysis of light water reactors

        Safavi Amir,Esteki Mohammad Hossein,Mirvakili Seyed Mohammad,Arani Mehdi Khaki 한국원자력학회 2020 Nuclear Engineering and Technology Vol.52 No.8

        Due to ever-growing advancements in computers and relatively easy access to them, many efforts have been made to develop high-fidelity, high-performance, multi-physics tools, which play a crucial role in the design and operation of nuclear reactors. For this purpose in this study, the neutronic Monte Carlo and thermal-hydraulic sub-channel codes entitled MCNP and COBRA-EN, respectively, were applied for external coupling with each other. The coupled code was validated by code-to-code comparison with the internal couplings between MCNP5 and SUBCHANFLOW as well as MCNP6 and CTF. The simulation re-sults of all code systems were in good agreement with each other. Then, as the second problem, the core of the VVER-1000 v446 reactor was simulated by the MCNP4C/COBRA-EN coupled code to measure the capability of the developed code to calculate the neutronic and thermohydraulic parameters of real and industrial cases. The simulation results of VVER-1000 core were compared with FSAR and another nu-merical solution of this benchmark. The obtained results showed that the ability of the MCNP4C/COBRA-EN code for estimating the neutronic and thermohydraulic parameters was very satisfactory.

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