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RISS 인기검색어
- 검색키워드
- 저자 : Rita Mary Aruna (검색결과 2 건)
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Angeline, T.,Aruna, Rita Mary,Devi, K. Rama,Jeyaraj, Nirmala The Korean Society for Integrative Biology 2007 Integrative biosciences Vol.11 No.2
Oxidative stress is prerequisite for the development of atherosclerosis. Apart from the traditional risk factors that contribute to this devastating condition, in the past few decades, much attention has been focused on plasma total homocysteine mainly because of its strong association with coronary artery disease. It has been suggested that homocysteine induces oxidative stress and hence the present work was undertaken to assess the total homocysteine status and plasma total antioxidant capacity in the acute myocardial infarction (AMI) patients among Tamil population. The study subjects included only the Tamil population. Blood samples were collected from 100 AMI patients and 100 controls. Plasma was separated and the total antioxidant status was assessed as a measure of ferric reducing power of antioxidants using spectrophotometric method. Plasma total homocysteine concentrations were assessed by automated chemiluminescence method. While Total antioxidant status was significantly decreased, the plasma homocysteine concentrations were elevated in AMI patients compared to the controls. However, there was no correlation between the homocysteine levels and total antioxidant status. The findings of this study may have therapeutic implications, including food sources rich in antioxidants for all AMI patients to minimize the effect of free radicals formed during oxidative stress among Tamil population.
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T. Angeline,Rita Mary Aruna,K. Rama Devi,Nirmala Jeyaraj 한국통합생물학회 2007 Animal cells and systems Vol.11 No.2
Oxidative stres is prerequisite for the developmentof atherosclerosis. Apart from the traditional risk factors thatcontribute to this devastating condition, in the past fewdecades, much attention has been focused on plasma totalhomocysteine mainly because of its strong association withhomocysteine induces oxidative stress and hence the presentwork was undertaken to assess the total homocysteinestatus and plasma total antioxidant capacity in the acutemyocardial infarction (AMI) patients among Tamil population.The study subjects included only the Tamil population. Bloodsamples were collected from 100 AMI patients and 100controls. Plasma was separated and the total antioxidantstatus was assessed as a measure of ferric reducing powerof antioxidants using spectrophotometric method. Plasmatotal homocysteine concentrations were assessed byantioxidant status was significantly decreased, the plasmahomocysteine concentrations were elevated in AMI patientscompared to the controls. However, there was no correlationbetwen the homocysteine levels and total antioxidantstatus. The findings of this study may have therapeuticimplications, including food sources rich in antioxidants forall AMI patients to minimize the effect of free radicals formedduring oxidative stress among Tamil population.
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