http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Rama Raju, G. Seeta,Pavitra, E.,Nagaraju, Goli,Sekhar, S. Chandra,Ghoreishian, Seyed Majid,Kwak, Cheol Hwan,Yu, Jae Su,Huh, Yun Suk,Han, Young-Kyu The Royal Society of Chemistry 2018 Journal of Materials Chemistry A Vol.6 No.27
<P>Evolution of a simple, efficient and reproducible strategy for the rational design of hierarchically structured metal chalcogenide-based supercapacitors has attracted considerable research interest in recent years. Herein, a facile wet-chemistry approach is employed to design three-dimensional forest-like porous nickel sulfide nanotrees on nickel foam (NiS NTs/Ni foam) for use as a cathode material in hybrid supercapacitors. The growth time plays a crucial role in controlling the surface morphology, and the optimal growth conditions (3 h at 85 °C) led to the growth of forest-like NiS NTs/Ni foam with reliable adherence. The forest-like NiS NTs/Ni foam shows maximum areal and specific capacities of 752.71 μA h cm<SUP>−2</SUP> and 342.1 mA h g<SUP>−1</SUP> at a current density of 4 mA cm<SUP>−2</SUP>, with an excellent cycling stability of 89.4%. This result is primarily due to the availability of more surface-active sites in the well-defined hierarchical architecture, which allow the rapid diffusion of electrolyte ions and minimize the electron transport limitation. Utilizing the hierarchical NiS NTs/Ni foam as a cathode and activated carbon-based anode, we further fabricated a hybrid supercapacitor, which demonstrates a wide potential window of 1.6 V with high areal energy and power densities of 0.472 mW h cm<SUP>−2</SUP> and 21.5 mW cm<SUP>−2</SUP>, respectively. The fabricated hybrid supercapacitor is successfully utilized to drive various electronic gadgets for real-life applications. The electrochemical performance of a hierarchically structured NiS-based binder-free electrode with our facile approach paves a new pathway for the development of novel metal chalcogenides for high-performance hybrid supercapacitors.</P>
Targeting autophagy in gastrointestinal malignancy by using nanomaterials as drug delivery systems
Raju, G. Seeta Rama,Pavitra, E.,Merchant, Neha,Lee, Hoomin,Prasad, Ganji Lakshmi Vara,Nagaraju, Ganji Purnachandra,Huh, Yun Suk,Han, Young-Kyu Elsevier 2018 Cancer letters Vol.419 No.-
<P><B>Abstract</B></P> <P>Autophagy is a conserved catabolic process involving large protein degradation by a ubiquitous autophagosomic signaling pathway, which is essential for cellular homeostasis. It is triggered by environmental factors such as stress, lack of nutrients, inflammation, and eliminating intracellular pathogens. Although the mechanisms underlying autophagy are still unclear, increasing evidence illuminates the magnitude of autophagy in a wide range of physiological processes and human diseases. Simultaneously, research community has focused on the triggering of autophagy by the internalization of engineered nanomaterials, which indicates a new line of revolution in cancer cure. However, most studies on nanoparticle-induced autophagy focus on brain, breast, and cervical cancers; limited reports are available on gastrointestinal (GI) cancers. Therefore, the aim of this mini review is to discuss in detail the role of autophagy in GI malignancy and the status of research on nanoparticle-induced autophagy.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Role of autophagy in GI growth and metastasis. </LI> <LI> Autophagy as a new therapeutic target in GI malignancy. </LI> <LI> Use of nanoparticles as diagnostic and therapeutic agents in GI malignancy. </LI> <LI> Modulation of autophagy by nanoparticles as drug delivery carriers. </LI> </UL> </P>
Raju, G. Seeta Rama,Pavitra, E.,Bharat, L. Krishna,Rao, Gattupalli Manikya,Jeon, Tae-Joon,Huh, Yun Suk,Han, Young-Kyu Elsevier 2018 CERAMICS INTERNATIONAL Vol.44 No.12
<P><B>Abstract</B></P> <P>Upconversion Sr<SUB>2</SUB>(Gd<SUB>.98-<I>x</I> </SUB>Er<SUB>.02</SUB>Yb<SUB> <I>x</I> </SUB>)<SUB>8</SUB>Si<SUB>6</SUB>O<SUB>26</SUB> (SGSO:2Er<SUP>3+</SUP>/<I>x</I>Yb<SUP>3+</SUP>) phosphor materials were synthesized using a citrate sol-gel process. X-ray diffraction patterns confirmed their hexagonal structure. Field emission scanning electron microscopy images of SGSO:2Er<SUP>3+</SUP>/<I>x</I>Yb<SUP>3+</SUP> phosphors depicted submicron particles. The enhanced upconversion luminescence properties of SGSO:2Er<SUP>3+</SUP>/<I>x</I>Yb<SUP>3+</SUP> phosphors were analysed as a function of Yb<SUP>3+</SUP> ion concentration and laser power. The energy transfer induced enhanced emission of the Er<SUP>3+</SUP>/ Yb<SUP>3+</SUP> ions co-doped SGSO phosphors was ascribed to multi-phonon relaxation. The calculated chromaticity coordinates of the SGSO:2Er<SUP>3+</SUP>/<I>x</I>Yb<SUP>3+</SUP> phosphors showed emissions could be tuned by changing Yb<SUP>3+</SUP> ion concentration. Optimized sample exhibited the chromaticity coordinate values near to the ultra-high definition television standard green emission coordinates.</P>
Raju, G. Seeta Rama,Pavitra, E.,Ko, Yeong Hwan,Yu, Jae Su The Royal Society of Chemistry 2012 Journal of materials chemistry Vol.22 No.31
<P>Stable CaMoO<SUB>4</SUB> spherulites were synthesized by a facile hydrothermal method using (NH<SUB>4</SUB>)<SUB>6</SUB>Mo<SUB>7</SUB>O<SUB>24</SUB>·4H<SUB>2</SUB>O as a Mo source and these spherulites were formed according to the theoretical predictions of the crystal splitting theory. Rietveld refinement and photoluminescence studies confirmed that the CaMoO<SUB>4</SUB> spherulites are defect-free. The CaMoO<SUB>4</SUB> spherulites showed greenish-blue emission and the single emitting component of CaMoO<SUB>4</SUB>:Eu<SUP>3+</SUP> spherulites led to a novel excitation induced efficient emission property like organic light emitting diodes. Cathodoluminescent properties of the CaMoO<SUB>4</SUB>:Eu<SUP>3+</SUP> exhibited individual emissions from MoO<SUB>4</SUB><SUP>2−</SUP> clusters and Eu<SUP>3+</SUP> ions. The white color emissions were clearly explained using Gaussian fitting curves. The corresponding CIE chromaticity coordinates provided their emission potentiality in the green, red and white regions for optical and biological applications.</P> <P>Graphic Abstract</P><P>Stable CaMoO<SUB>4</SUB> spherulites with tunable luminescent properties have been synthesized and the growth mechanism is in well agreement with the theoretical predictions of the crystal splitting theory. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2jm32049e'> </P>
Raju, G. Seeta Rama,Park, Jin Young,Jung, Hong Chae,Pavitra, E.,Moon, Byung Kee,Jeong, Jung Hyun,Kim, Jung Hwan Royal Society of Chemistry 2011 Journal of materials chemistry Vol.21 No.17
<P>The cathodoluminescence and the excitation induced photoluminescence properties have been investigated for the nanocrystalline Tb<SUP>3+</SUP>/Sm<SUP>3+</SUP>:Ca<SUB>2</SUB>Gd<SUB>8</SUB>Si<SUB>6</SUB>O<SUB>26</SUB> phosphors prepared by a solvothermal reaction method. The XRD patterns confirm their hexagonal structure. The green, orange and white emissions have been obtained by exciting at 275, 378, and 405 nm wavelengths, respectively. The corresponding CIE chromaticity coordinates are found to be in close proximity to the standard points in their respective regions. The cathodoluminescence at low accelerating voltage has also covered the entire visible region, resulting in white emission. These luminescent powders are expected to find potential applications in the development of LEDs and FEDs.</P> <P>Graphic Abstract</P><P>Single-emitting component (Tb<SUP>3+</SUP>/Sm<SUP>3+</SUP>:Ca<SUB>2</SUB>Gd<SUB>8</SUB>Si<SUB>6</SUB>O<SUB>26</SUB> phosphor) produces the white light as well as individual colors at different excitation wavelengths. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c0jm04337k'> </P>
Raju, Ganji Seeta Rama,Pavitra, Eluri,Lee, Hoomin,Nagaraju, Goli,Baskaran, Rengarajan,Yang, Su Geun,Kwak, Cheol Hwan,Nagaraju, Ganji Purnachandra,Huh, Yun Suk,Han, Young-Kyu Elsevier 2020 APPLIED SURFACE SCIENCE - Vol.505 No.-
<P><B>Abstract</B></P> <P>Rare-earth niobate compounds are excellent nonlinear optical materials. Unlike other niobate materials, gadolinium ortho-niobate (GdNbO<SUB>4</SUB>) is reported to be inert in the visible region. The synthesis of pure-phase GdNbO<SUB>4</SUB> with a definite morphology suitable for biomedical applications is still a great challenge. In this study, a novel strategy is introduced to successfully facilitate the bioavailability of GdNbO<SUB>4</SUB>:Eu<SUP>3+</SUP> luminescent material by harnessing the pre-ouzo effect during the synthesis of mesoporous GdNbO<SUB>4</SUB>:Eu<SUP>3+</SUP> nanospheroids. Because of the materialization of GdNbO<SUB>4</SUB> nanodomains, the mesoporous GdNbO<SUB>4</SUB> nanospheroids exhibit paramagnetic behaviour and allows the strong broadband excitation between 300 and 500 nm, which permits NbO<SUB>6</SUB> emissions to be obtained in the visible region, whereas Eu<SUP>3+</SUP> activated mesoporous GdNbO<SUB>4</SUB> nanospheroids produce an intense red emission under UV, near-UV and visible excitations. These mesoporous nanospheroids also demonstrate excellent cellular internalization for HCT116 and SW680 colon cancer cells and work in conjunction with optical and magnetic resonance imaging for the accurate diagnosis and prognosis of anatomical and physiological functions. The conjugation of chlorin e6 with mesoporous GdNbO<SUB>4</SUB>:Eu<SUP>3+</SUP> nanospheroids leads to efficient photodynamic therapy (PDT) in cancer treatment. Ultimately, our approach represents an advance in the use of mesoporous GdNbO<SUB>4</SUB>:Eu<SUP>3+</SUP> nanospheroids as multifunctional nanoprobes for multimodal imaging and PDT.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Mesoporous GdNbO<SUB>4</SUB>:Eu<SUP>3+</SUP> nanospheroids were synthesized by a hydrothermal reaction method<SUB>.</SUB> </LI> <LI> The formation mechanism of mesoporous GdNbO<SUB>4</SUB>:Eu<SUP>3+</SUP> nanospheroids was reported. </LI> <LI> The GdNbO<SUB>4</SUB> and GdNbO<SUB>4</SUB>:Eu<SUP>3+</SUP> nanodomains induced photoluminescence properties were investigated. </LI> <LI> The magnetic properties of GdNbO<SUB>4</SUB> and GdNbO<SUB>4</SUB>:Eu<SUP>3+</SUP> mesoporous nanospheroids were established. </LI> <LI> Multimodal bioimaging and photodynamic therapy of mesoporous GdNbO<SUB>4</SUB>:Eu<SUP>3+</SUP> nanospheroids were demonstrated. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Raju, G. Seeta Rama,Pavitra, E.,Rao, Gattupalli Manikya,Jeon, Tae-Joon,Jeon, Sie-Wook,Huh, Yun Suk,Han, Young-Kyu Elsevier 2018 JOURNAL OF ALLOYS AND COMPOUNDS Vol.756 No.-
<P><B>Abstract</B></P> <P>Fluorescence intensity ratio (FIR)-based optical thermometry has attracted a great deal of attention because it allows accurate and reliable temperature measurements with high spatial resolution and real-time monitoring. Herein, we report the novel Sr<SUB>2</SUB>Gd<SUB>8</SUB>(SiO<SUB>4</SUB>)<SUB>6</SUB>O<SUB>2</SUB>:Er<SUP>3+</SUP> (SGSO:Er<SUP>3+</SUP>) phosphor as an optical thermometry material. The sol-gel method is used to synthesize the oxyapatite structured SGSO:Er<SUP>3+</SUP> phosphors, which exhibits a rod-like morphology. The photoluminescence spectra of SGSO:Er<SUP>3+</SUP> phosphors displays two distinct green emission bands corresponding to the electronic transitions <SUP>2</SUP>H<SUB>11/2</SUB> → <SUP>4</SUP>I<SUB>15/2</SUB> and <SUP>4</SUP>S<SUB>3/2</SUB> → <SUP>4</SUP>I<SUB>15/2</SUB>. The temperature-induced variations in the FIR result in a maximum sensitivity of 3.4 × 10<SUP>−3</SUP> K<SUP>−1</SUP> at 463 K. Further, the CIE chromaticity coordinates do not shift from the green region when the temperature is increased from 303 to 483 K and the color purity only decreasing from 77.6 to 71.4%. The SGSO:2Er<SUP>3+</SUP> phosphor exhibits the color-purity of 93.5% when excited with low-energy electron beam. These results suggest that the SGSO:2Er<SUP>3+</SUP> phosphor is a promising material for optical temperature sensors and display devices.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Green-emitting Sr<SUB>2</SUB>Gd<SUB>8</SUB>(SiO<SUB>4</SUB>)<SUB>6</SUB>:Er<SUP>3+</SUP> is reported as a novel multifunctional material. </LI> <LI> Sr<SUB>2</SUB>Gd<SUB>8</SUB>(SiO<SUB>4</SUB>)<SUB>6</SUB>:Er<SUP>3+</SUP> phosphor exhibits a maximum sensitivity of 3.4 × 10<SUP>−3</SUP> K<SUP>−1</SUP> at 463 K. </LI> <LI> Green color-purity destruction under elevated thermal condition is only about 6%. </LI> <LI> Under low electron-beam excitation, phosphor unveil 93.5% green color-purity. </LI> </UL> </P>
Seeta Rama Raju, G.,Park, J.Y.,Jung, H.C.,Balakrishnaiah, R.,Moon, B.K.,Jeong, J.H. Elsevier 2011 CURRENT APPLIED PHYSICS Vol.11 No.3
Different concentrations of trivalent praseodymium (Pr<SUP>3+</SUP>) ions activated GdAlO<SUB>3</SUB> nanophosphors were synthesized by solvothermal reaction method. Thermogravimetric/differential thermal analysis (TG/DTA) and X-ray diffraction (XRD) measurements were used to investigate the phase transformations that occur during the preparation of these phosphors. The morphology of the powder after heat treatment was observed by scanning electron microscopy (SEM). The luminescent studies on these compounds have been carried out from the measurements of their photoluminescence (PL) and photoluminescence excitation (PLE) spectra. The PL spectra show blue-green emission corresponding to the f-f transitions of Pr<SUP>3+</SUP> (<SUP>3</SUP>P<SUB>0</SUB> -> <SUP>3</SUP>H<SUB>4</SUB>) and red emission corresponding to the f-f transition of Pr<SUP>3+</SUP> (<SUP>3</SUP>P<SUB>0</SUB> -> <SUP>3</SUP>H<SUB>6</SUB>) by monitoring the excitation with f-f transition of Pr<SUP>3+</SUP> (<SUP>3</SUP>H<SUB>4</SUB> -> <SUP>3</SUP>P<SUB>2</SUB>) at 449 nm. Emission mechanism in these systems has also been elucidated by an energy level scheme.