http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Porch, Adrian (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
Glioma Immunotherapy: Advances and Challenges for Spinal Cord Gliomas
Clare Grady,Kaitlyn Melnick,Ken Porche,Farhad Dastmalchi,Daniel J. Hoh,Maryam Rahman,Ashley Ghiaseddin 대한척추신경외과학회 2022 Neurospine Vol.19 No.1
Spinal cord gliomas are rare entities that often have limited surgical options. Immunotherapy has shown promise in intracranial gliomas with some research suggesting benefit for spinal cord gliomas. A focused review of immunotherapies that have been investigated in spinal cord gliomas was performed. The primary methods of immunotherapy investigated in spinal cord gliomas include immune checkpoint inhibitors, adoptive T-cell therapies, and vaccine strategies. There are innumerable challenges that must be overcome to effectively apply immunotherapeutic strategies to the spinal cord gliomas including low incidence, few antigenic targets, the blood spinal cord barrier, the immunosuppressive tumor microenvironment and neurotoxic treatment effects. Nonetheless, research has suggested ways to overcome these challenges and treatments have been effective in case reports for metastatic non-small cell lung cancer, melanoma, midline glioma and glioblastoma. Current therapies for spinal cord gliomas are markedly limited. Further research is needed to determine if the success of immunotherapy for intracranial gliomas can be effectively applied to these unique tumors.
-
Microwave cavity perturbation of nitrogen doped nano-crystalline diamond films
Cuenca, Jerome A.,Sankaran, Kamatchi Jothiramalingam,Pobedinskas, Paulius,Panda, Kalpataru,Lin, I-Nan,Porch, Adrian,Haenen, Ken,Williams, Oliver A. Elsevier 2019 Carbon Vol.145 No.-
<P><B>Abstract</B></P> <P>Non-contact and non-destructive electrical conductivity measurements of nitrogen doped nano-crystalline diamond films have been demonstrated using a microwave cavity perturbation system. The conductivity of the films was controlled by simply varying the CH<SUB>4</SUB> gas concentration during microwave plasma assisted chemical vapour deposition, thereby promoting the formation of sp<SUP>2</SUP> carbon at the grain boundaries. The presence of sp<SUP>2</SUP> carbon is verified through Raman spectroscopy, x-ray photoelectron spectroscopy and electron energy loss spectroscopy, while scanning electron microscopy confirms an increasing surface area for sp<SUP>2</SUP> to form. The microwave cavity perturbation results show that the measured cavity quality factor varies with CH<SUB>4</SUB> concentration. The extraction of conductivity is achieved through a depolarisation model, which must be considered when the sample is smaller than the cavity and through both electric and magnetic field perturbations. The microwave measurements are comparable to contacting and damaging measurements when the film conductivity is greater than the substrate, thus demonstrating an invaluable method for determining conductivity without the need for depositing any electrodes on the film.</P>
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
