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- 저자 : Oyola, Samuel O. (검색결과 1 건)
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Kumar, Himansu,Park, Woncheoul,Lim, Dajeong,Srikanth, Krishnamoorthy,Kim, Jun-Mo,Jia, Xin-Zheng,Han, Jian-Lin,Hanotte, Olivier,Park, Jong-Eun,Oyola, Samuel O. Elsevier 2020 Genomics Vol.112 No.2
<P><B>Abstract</B></P> <P>We analyzed the whole genomes of cecum microbiomes of Ethiopian indigenous chickens from two distinct geographical zones: Afar (AF) district (Dulecha, 730 m above sea level) and Amhara (AM) district (Menz Gera Midir, 3300 m). Through metagenomic analysis we found that microbial populations were mainly dominated by <I>Bacteroidetes</I> and <I>Firmicutes.</I> We identified 2210 common genes in the two groups. LEfSe showed that the distribution of <I>Coprobacter, Geobacter, Cronobacter, Alloprevotella,</I> and <I>Dysgonomonas</I> were more abundant in AF than AM. Analyses using KEGG, eggNOG, and CAZy databases indicated that the pathways of metabolism, genetic information processing, environmental information processing, and cellular process were significantly enriched. Functional abundance was found to be associated with the nutrient absorption and microbial localization of indigenous chickens. We also investigated antibiotic resistant genes and found antibiotics like LSM, cephalosporin, and tetracycline were significantly more abundant in AF than AM.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Microbial comparison of scavenging chicken's cecum content between high land and low land region of Ethiopia. </LI> <LI> Differential functional annotations of identified microbiota from both regions. </LI> <LI> Antibiotic resistant genes identification and their differential abundance. </LI> </UL> </P>
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