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        Comparison of characteristics and ventilatory course between coronavirus disease 2019 and Middle East respiratory syndrome patients with acute respiratory distress syndrome

        Imran Khalid,Romaysaa M Yamani,Maryam Imran,Muhammad Ali Akhtar,Manahil Imran,Rumaan Gul,Tabindeh Jabeen Khalid,Ghassan Y Wali 대한중환자의학회 2021 Acute and Critical Care Vol.36 No.3

        Background: Both coronavirus disease 2019 (COVID-19) and Middle East respiratory syndrome (MERS) can cause acute respiratory distress syndrome (ARDS); however, their ARDS course and characteristics have not been compared, which we evaluate in our study. Methods: MERS patients with ARDS seen during the 2014 outbreak and COVID-19 patients with ARDS admitted between March and December 2020 in our hospital were included, and their clinical characteristics, ventilatory course, and outcomes were compared. Results: Forty-nine and 14 patients met the inclusion criteria for ARDS in the COVID-19 and MERS groups, respectively. Both groups had a median of four comorbidities with high Charlson comorbidity index value of 5 points (P>0.22). COVID-19 patients were older, obese, had significantly higher initial C-reactive protein (CRP), more likely to get trial of high-flow oxygen, and had delayed intubation (P≤0.04). The postintubation course was similar between the groups. Patients in both groups experienced a prolonged duration of mechanical ventilation, and majority received paralytics, dialysis, and vasopressor agents (P>0.28). The respiratory and ventilatory parameters after intubation (including tidal volume, fraction of inspired oxygen, peak and plateau pressures) and their progression over 3 weeks were similar (P>0.05). Rates of mortality in the ICU (53% vs. 64%) and hospital (59% vs. 64%) among COVID-19 and MERS patients (P≥0.54) were very high. Conclusions: Despite some distinctive differences between COVID-19 and MERS patients prior to intubation, the respiratory and ventilatory parameters postintubation were not different. The higher initial CRP level in COVID-19 patients may explain the steroid responsiveness in this population.

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        Determinants of the willingness of the general population to get vaccinated against COVID-19 in a developing country

        Abdel-Hameed Al-Mistarehi,Khalid A. Kheirallah,Ahmed Yassin,Safwan Alomari,Maryam K. Aledrisi,Ehab M. Bani Ata,Nouran H. Hammad,Asim N. Khanfar,Ali M. Ibnian,Basheer Y. Khassawneh 대한백신학회 2021 Clinical and Experimental Vaccine Research Vol.10 No.2

        Purpose: Vaccination is a cost-efficient intervention to slow the spread of the coronavirus disease 2019 (COVID-19) pandemic. This study aims to assess the population’s willingness to take the COVID-19 vaccine in Jordan and investigate potential determinants of their acceptance. Materials and Methods: This study used an online survey distributed in November 2020, before introducing the vaccine, with items investigating socio-demographic characteristics, seasonal flu vaccination history, COVID-19 vaccine acceptance once available, and factors affecting their decision-making. Also, “COVID-19 risk perception” and beliefs toward COVID-19 vaccine benefits and barriers were assessed. Results: A total of 2,208 participants completed the survey with a participation rate of 13.1%. The mean±standard deviation age was 33.2±13.5, and 55.7% were females. Study participants were almost equally distributed between willingness, unwillingness, and indecision to take the COVID-19 vaccine (30.4%, 36.4%, and 31.5%, respectively). Younger adults, males, and those who were not married, do not have children, have a bachelor or higher education, employees or being students, healthcare workers, and those who reported receiving flu vaccine had higher rates of COVID-19 vaccine acceptance compared to their counterparts (p<0.001 for each category). COVID-19 risk perception, and perceived vaccine benefits, and barriers were significant predictors of intention. Among those undecided or unwilling to take the COVID-19 vaccine, its safety and side effects were the most common concerns. Conclusion: The low rate of COVID-19 vaccine acceptance in a developing country is alarming, and a significant proportion are indecisive. Interventions to elevate vaccine acceptance by addressing its safety and efficacy and targeting vulnerable groups are recommended.

      • Use of Blockchain to Support the Security of Internet of Things: A Review

        Saher Un Nisa,Maryam Khalid International Journal of Computer ScienceNetwork S 2023 International journal of computer science and netw Vol.23 No.7

        Internet of Things (IoT) is now spreading everywhere. It's the technology of every person's need so we can't step back from IoT but we can secure it as it is spreading quickly so it has greater chances of danger and being misused. There is an urgent need to make IoT devices secure from getting cracked or hacked. A lot of methods had tried and still trying to mitigate IoT security issues. In this paper Blockchain is going to be the solution of most of the IoT issues or problems. We have discussed or highlighted security issues with centralized IoT and then provided solution of such security challenges through the use of blockchain because is based on a decentralized technology that is hard to modify or update.

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