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Yang, Guo-Tao,Wang, Juan,Xu, Tong-Zhen,Sun, Xue-Fei,Luan, Zi-Ying Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.3
Esophageal cancer represents the fourth most common gastrointestinal cancer and generally confers a poor prognosis. Prostaglandin-producing cyclo-oxygenase has been implicated in the pathogenesis of esophageal cancer growth. Here we report that prostaglandin dehydrogenase, the major enzyme responsible for prostaglandin degradation, is significantly reduced in expression in esophageal cancer in comparison to normal esophageal tissue. Reconstitution of PGDH expression in esophageal cancer cells suppresses cancer cell growth, at least in part through preventing cell proliferation and promoting cell apoptosis. The tumor suppressive role of PGDH applies equally to both squamous cell carcinoma and adenocarcinoma, which enriches our understanding of the pathogenesis of esophageal cancer and may provide an important therapeutic target.
Sun Shi jun,Zhao Yun duo,Luan Ying Tao 국제온돌학회 2013 International Journal of Ondol Vol.2013 No.-
Straw board is renewable natural building material with the advantages of green environmental protection, strong applicability. But it hadn’t been promoted because of many reasons such as technology and economy. Through the analysis of the unique advantages and the recent new cases of straw board buildings in Harbin, and the current obstacles to application, The effective ways and the feasible solutions to promote sustainable straw board buildings are summarized.