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Djordjije Saranovic,Jelena Djokic Kovac,Srbislav Knezevic,Snezana Susnjar,Aleksandra Djuric Stefanovic,Dragana Sobic Saranovic,Vera Artiko,Vladimir Obradovic,Dragan Masulovic,Marjan Micev,Predrag Pesk 한국유방암학회 2011 Journal of breast cancer Vol.14 No.3
Gastrointestinal metastases from invasive lobular breast cancer are uncommon with the stomach and small intestines being the most common metastatic sites. Peritoneal and rectal metastases are very rare and only rarely occur as the first manifestation of disease. We herein report the case of a 47-year-old woman who presented with abdominal carcinomatosis as a first sign of invasive lobular breast carcinoma (ILC). Identifying the most important immunohistochemical markers for ILC: gross cystic disease fluid protein 15, estrogen and progesterone receptors enabled a correct diagnosis. After a six year disease-free period, relapse occurred with severe obstruction due to rectal metastasis from lobular breast carcinoma. Since there was no widespread metastatic disease, surgery with concomitant hormonal therapy was performed.