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Trafficking Inhibition of Bruceanol B as a Radical-Producing Antibiotic
Lee, Do-Seung,Boo, Kyung-Hwan,Woo, Jin-Kyu,Hong, Quan-Chun,Cho, Somi K.,Park, Se-Pill,Lee, Dong-Sun,Riu, Key Zung The Korean Society for Applied Biological Chemistr 2011 Applied Biological Chemistry (Appl Biol Chem) Vol.54 No.2
Bruceanol B, isolated from a soil microbe strain DS4, generated oxygen radicals in Bacillus subtilis lysates. Bruceanol B inhibited the trafficking of viral glycoprotein in virus-infected baby hamster kidney (BHK) cells. Bruceanol B also effectively inhibited syncytium formation in a dose-dependent manner. However, glycoprotein synthesis was not affected by the compound. Results indicate that bruceanol B generating oxygen radical has inhibitory activity in the trafficking of viral glycoprotein of BHK cell.
Anti-bacterial and Anti-viral Activity of Extracts from Paeonia lactiflora Roots
Boo, Kyung-Hwan,Lee, Do-Seung,Woo, Jin-Kyu,Ko, Seung-Hee,Jeong, Eun-Hyoung,Hong, Quan-Chun,Riu, Key Zung,Lee, Dong-Sun The Korean Society for Applied Biological Chemistr 2011 Applied Biological Chemistry (Appl Biol Chem) Vol.54 No.1
Methanol extracts of Paeonia lactiflora roots (Radix Paeaniae Lactiflora) had antibacterial activity against Bacillus subtilis. These extracts generated superoxide radicals in the B. subtilis lysate. However, the radicals were strongly detoxified by the addition of superoxide dismutase, an indication that superoxide radicals are important in the antibacterial actions of the extracts. The root extracts also showed a pivotal inhibition role in trafficking of viral glycoprotein in virusinfected baby hamster kidney (BHK) cells. The methanol extract effectively inhibited syncytium formation in a concentration-dependent, and it did not affect glycoprotein synthesis. These results suggest that oxygen radical affect the transport process of viral glycoprotein without its synthesis.
Dihydrobenzofuran Norlignans from the Leaves of Cedrela sinensis A. Juss
Lee, Ik-Soo,Kim, Hong-Jin,Youn, Ui-Jung,Chen, Quan-Cheng,Kim, Jin-Pyo,Ha, Do Thi,Ngoc, Tran Minh,Min, Byung-Sun,Lee, Sang-Myung,Jung, Hyun-Ju,Na, Min-Kyun,Bae, Ki-Hwan WILEY-VCH Verlag 2010 Helvetica chimica acta Vol.93 No.2
<P>Two new norlignans, cedralins A (1) and B (2), were isolated from the leaves of Cedrela sinensis. Their structures were established by extensive spectroscopic studies and chemical evidence. The absolute configurations of these compounds were determined by comparing their CD spectra with those of known compounds. In addition, their in vitro cytotoxic activity against two human-cancer cell lines was evaluated.</P> <B>Graphic Abstract</B> <P> <img src='wiley_img/0018019X-2010-93-2-HLCA200900180-content.gif' alt='wiley_img/0018019X-2010-93-2-HLCA200900180-content'> </P>
FGW-FER: Lightweight Facial Expression Recognition with Attention
Huy-Hoang Dinh,Hong-Quan Do,Trung-Tung Doan,Cuong Le,Ngo Xuan Bach,Tu Minh Phuong,Viet-Vu Vu 한국인터넷정보학회 2023 KSII Transactions on Internet and Information Syst Vol.17 No.9
The field of facial expression recognition (FER) has been actively researched to improve human-computer interaction. In recent years, deep learning techniques have gained popularity for addressing FER, with numerous studies proposing end-to-end frameworks that stack or widen significant convolutional neural network layers. While this has led to improved performance, it has also resulted in larger model sizes and longer inference times. To overcome this challenge, our work introduces a novel lightweight model architecture. The architecture incorporates three key factors: Depth-wise Separable Convolution, Residual Block, and Attention Modules. By doing so, we aim to strike a balance between model size, inference speed, and accuracy in FER tasks. Through extensive experimentation on popular benchmark FER datasets, our proposed method has demonstrated promising results. Notably, it stands out due to its substantial reduction in parameter count and faster inference time, while maintaining accuracy levels comparable to other lightweight models discussed in the existing literature.
EQCM studies of the effect of sulfamic acid on the formation Cu-Se compounds
Dang Thi Bich Hop,Pham Hong Quang,Duc H. Tran,Do Thi Kim Anh,Do Phuc Quan,Ngo Dinh Sang,W. B. K. Putri 한양대학교 세라믹연구소 2015 Journal of Ceramic Processing Research Vol.16 No.1
A combination of Cyclic Voltammetry (CV) and Electrochemical Quartz Crystal Microbalance (EQCM) has been used to study the effect of sulfamic acid as a complexing agent on the formation of Cu-Se compounds. The values of the equivalent atomic mass (M/z) grown at the gold EQCM sensor during electrodeposition at varying potentials and constant potentials were analyzed to understand the mechanism of the growing process. It was found that sulfamic acid does not affect so much the deposition of Cu in the absence of Se. However, when Cu and Se are present simultaneously, sulfamic acid causes and facilitates the formation of Cu-Se compounds. Furthermore, at a high concentration, sulfamic acid causes a mass-loss process, leading to a change of composition. A suitable concentration of sulfamic acid can be concerned from these studies.
( Dong Sun Lee ),( Key Zung Riu ),( Kyung Hwan Boo ),( Do Seung Lee ),( Jin Kyu Woo ),( Seung Hee Ko ),( Eun Hyoung Jeong ),( Quan Chun Hong ) 한국응용생명화학회(구 한국농화학회) 2011 Applied Biological Chemistry (Appl Biol Chem) Vol.54 No.1
Methanol extracts of Paeonia lactiflora roots (Radix Paeaniae Lactiflora) had antibacterial activity against Bacillus subtilis. These extracts generated superoxide radicals in the B. subtilis lysate. However, the radicals were strongly detoxified by the addition of superoxide dismutase, an indication that superoxide radicals are important in the antibacterial actions of the extracts. The root extracts also showed a pivotal inhibition role in trafficking of viral glycoprotein in virusinfected baby hamster kidney (BHK) cells. The methanol extract effectively inhibited syncytium formation in a concentration-dependent, and it did not affect glycoprotein synthesis. These results suggest that oxygen radical affect the transport process of viral glycoprotein without its synthesis.