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Severe anorexia and weight loss induced by tacrolimus in kidney transplant recipients
Hwang Hong Pil,Yu Hee Chul,Chung Byeoung Hoon,강경표,Kim Won,Park Sung Kwang,Lee Sik 대한이식학회 2021 Korean Journal of Transplantation Vol.35 No.2
Common neuropsychiatric complications of tacrolimus include tremors, fatigue, headache, sleep disorders, paranoid reactions, and anxiety. Other, more serious complications include encephalopathy, convulsions, confusion, and coma. To our knowledge, however, severe weight loss by anorexia has not been reported as a neuropsychiatric adverse effect of tacrolimus given to adult kidney transplant recipients. In this article we present two cases of severe anorexia and weight loss associated with tacrolimus that appeared to reverse with cyclosporine.