http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Guoqing Wan (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
Evaluation of Warp Knitting and Mechanical Damage of Staple Fiber Composite Yarn
Guoqing Hao,Ailan Wan 한국섬유공학회 2023 Fibers and polymers Vol.24 No.10
In order to study the ability to knit and mechanical damage of short fiber composite yarn (SFCY) in the warp knitting process, the core-spun yarn, compact-spinning and blended yarn by ring spinning were knitted by the tricot warp-knitting machine with three different structures and speeds. The mechanical properties, the hairiness and appearance of the yarns were characterized before and after warp knitting. The results demonstrated that the breaking strength and elongation at break of the yarns decreased after warp knitting. As the speed of the machine increased, the breaking strength of the yarn continued to decrease, reaching a maximum of 28%. With the increase in under lapping, the elongation at break of the yarn reached 19% compared with the original yarn. The hairiness index of the yarns had increased significantly from the microscopic morphology. The cotton/polyamide core-spun yarn was the best for warp knitting of the four yarns. And the compact-spinning yarn is more suitable for warp knitting than ring-spun yarn.
-
( Tao Li ),( Yingchun Wan ),( Lijuan Sun ),( Shoujun Tao ),( Peng Chen ),( Caihua Liu ),( Ke Wang ),( Changyu Zhou ),( Guoqing Zhao ) 한국응용약물학회 2019 Biomolecules & Therapeutics(구 응용약물학회지) Vol.27 No.4
There is accumulating evidence that microRNAs are emerging as pivotal regulators in the development and progression of neuropathic pain. MicroRNA-15a/16 (miR-15a/16) have been reported to play an important role in various diseases and inflammation response processes. However, whether miR-15a/16 participates in the regulation of neuroinflammation and neuropathic pain development remains unknown. In this study, we established a mouse model of neuropathic pain by chronic constriction injury (CCI) of the sciatic nerves. Our results showed that both miR-15a and miR-16 expression was significantly upregulated in the spinal cord of CCI rats. Downregulation of the expression of miR-15a and miR-16 by intrathecal injection of a specific inhibitor significantly attenuated the mechanical allodynia and thermal hyperalgesia of CCI rats. Furthermore, inhibition of miR-15a and miR-16 downregulated the expression of interleukin-1β and tumor-necrosis factor-αin the spinal cord of CCI rats. Bioinformatic analysis predicted that G protein-coupled receptor kinase 2 (GRK2), an important regulator in neuropathic pain and inflammation, was a potential target gene of miR-15a and miR-16. Inhibition of miR-15a and miR-16 markedly increased the expression of GRK2 while downregulating the activation of p38 mitogen-activated protein kinase and NF-κB in CCI rats. Notably, the silencing of GRK2 significantly reversed the inhibitory effects of miR-15a/16 inhibition in neuropathic pain. In conclusion, our results suggest that inhibition of miR-15a/16 expression alleviates neuropathic pain development by targeting GRK2. These findings provide novel insights into the molecular pathogenesis of neuropathic pain and suggest potential therapeutic targets for preventing neuropathic pain development.
-
Feng Huang,Ban Zhang,Xingchen Liu,Jinyang Xiang,Guoqing Wan,Miaodi Qu 한국강구조학회 2022 International Journal of Steel Structures Vol.22 No.1
The primary error sources of engineering design for bolted beam reaction system with large size are mainly from the deformation of structure, mechanical behavior of connection joints. In addition, the simplifi ed calculation method of bolted connection has not formed a unifi ed understanding. A vertical static load test was carried out in the laboratory, and the deformation laws of the reaction beam were analyzed to obtain the mechanical characteristics of the connection joints by controlling the defl ection of the reaction beam. The composite eff ect coeffi cient k l of the variable section panel structure was introduced to the theoretical solution of the defl ection of the variable cross-section beam. Simultaneously, the fi nite element method was employed to establish the detailed model of the beam reaction system. The mechanical behavior of the reaction beam and the bolted joint are extensively studied, and the simplifi ed method of bolted joint is improved. The bolted connection is simplifi ed as a semi-rigid joint, and then the theoretical formula is proposed to calculate the defl ection and deformation of the beam structure under bolted connection. The defl ection and deformation of the reaction beam by the test and theoretical formula are consistent. The results show that the theoretical formula can well calculate the defl ection and deformation of structure members under bolted connection.
ScienceON연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
