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Hong Wook Kim,정재흥,Do Kyung Kim,강호원,구자윤,Hyun Jin Jung,Eu Chang Hwang,Guideline Development Committee in the Kor. Ass. of Urogenital Tract Infection and Inflammation 대한요로생식기감염학회 2020 Urogenital Tract Infection Vol.15 No.2
This article is the fifth translation of a GRADE series published in the BMJ for incorporating the considerations of resources use into grading recommendations. Clinical recommendations inevitably involve judgments about the allocation of resources use (costs). Although costs differ from typical healthcare outcomes, such as mortality, morbidity, and quality of life, costs are another potentially important outcome that differs across and within a jurisdiction. A balance sheet is a useful method for determining if the net benefits are worth the incremental costs. Resource use, not just monetary values, should always be presented in an evidence profile. Formal economic modeling may or may not help judge the certainty of the evidence for resource use.
정현진,황의창,Do Kyung Kim,강호원,Ja Yoon Ku,Hong Wook Kim,정재흥,Guideline Development Committee in the Kor. Ass. of Urogenital Tract Infection and Inflammation 대한요로생식기감염학회 2020 Urogenital Tract Infection Vol.15 No.3
This article is the last of a series providing guidance for the use of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system for rating the quality of evidence and grading the strength of recommendations in systematic reviews and clinical practice guidelines. Formulating recommendations with the applicable evidence can be difficult due to the large and diverse nature of guideline committees. This article describes a simple technique called the GRADE grid for clarifying the opinions from guideline panels, dealing with disagreement, and achieving consensus among guideline panels. The grid may be helpful for any guideline groups who want to use GRADE to develop their guidelines and achieve consensus or understand the patterns of uncertainty that surround the interpretation of scientific evidence.
정재흥,Do Kyung Kim,강호원,Ja Yoon Ku,Hyun Jin Jung,Hong Wook Kim,Eu Chang Hwang,Guideline Development Committee in the Kor. Ass. of Urogenital Tract Infection and Inflammation 대한요로생식기감염학회 2020 Urogenital Tract Infection Vol.15 No.1
This article is the fourth translation of a GRADE series published in the BMJ, which graded the quality of evidence and strength of recommendations for diagnostic tests or strategies, as a comprehensive and transparent approach for developing re-commendations. Randomized trials for diagnostic approaches represent the ideal study design for intervention studies. On the other hand, cross-sectional or cohort studies with a direct comparison of the test results with an appropriate reference standard can provide high-quality evidence. The guideline panel must be reminded that the test accuracy is a surrogate for patient-important outcomes, so such studies often provide a low quality of evidence for recommendations regarding diagnostic tests, even when the studies do not have serious limitations. Diagnostic accuracy studies showing that a diagnostic test or strategy improves important patient outcomes will require the availability of effective treatment, reduction of test- related adverse effects or anxiety, or improvement of the patients’ well-being from prognostic information. Therefore, it is important to assess the directness of the test results regarding the consequences of diagnostic recommendations that are im-portant to patients.