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Microstructure and Tensile Properties of Mg–5Zn Alloy Containing Ca
Elaheh Maleki,Farzad Shahri,Masoud Emamy 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.6
The present study aimed at investigating the effect of Ca (0–3 wt%) on the microstructure and tensile properties of as-castand as-extruded Mg–Zn alloy, in which tensile tests, X-ray diffraction, SEM, EDX and texture analysis were used to evaluatethese features. Based on the results obtained, it is shown that the average grain size decreased from 305 to 84 μm byadding 3 wt% Ca to the as-cast Mg–Zn alloy. XRD and SEM results reveal that the dominant second phase in the presenceof Ca is Ca2Mg6Zn3which is formed continuously between dendrite arms spacing. It has been observed that the additionof 0.1 wt% Ca, significantly enhanced both UTS and elongation of as-cast alloy. It is found that the size of DRXed grainsdecreases with the increase of Ca (4 μm with 3 wt% Ca addition) after hot-extrusion. Further, it has been observed thatUltimate tensile strength (UTS) and elongation values of extruded alloys containing Ca are enhanced and the best result isobtained for Mg–5Zn–0.1Ca sample. Ultimate tensile strength (UTS) of 351 MPa and elongation percentage of 24% areobtained for Mg–5Zn–0.1Ca extruded alloy.
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Ashkan Karbasi,Ali Abbasi,Abbas Mohagheghi,Jalal Poorolajal,Farzad Emami,Shirin Moradkhani,Iraj Khodadadi,Mahmoud Gholyaf,Heidar Tavilani 전남대학교 의과학연구소 2024 전남의대학술지 Vol.60 No.1
Contrast-induced acute kidney injury (CI-AKI) is a frequent challenge following the injection of contrast media and its subsequent oxidative stress. The aim of the present study was to evaluate the preventive effects of coenzyme Q10 (Q10), as a mitochondrial-targeted antioxidant in CI-AKI in diabetic patients, who account for a large proportion of angiographic cases. A total of 118 diabetic patients were randomly assigned to receive 120 mg of oral coenzyme Q10 (Q10 group) or placebo (Placebo group) for four days, starting 24 hours before contrast media injection. Blood urea nitrogen (BUN), serum and urinary creatinine, estimated glomerular filtration rate (eGFR), urinary malondialdehyde (UMDA), urinary total antioxidant capacity (UTAC), and urinary mitochondrial to nuclearDNA ratios (mtDNA/nDNA ratio) were evaluated before and after the treatment period. Urine sediments were also evaluated to report the urine microscopy score (UMS).The levels of BUN, serum and urine creatinine, and UMS were similar in the Q10 and placebo groups. EGFR was lower in the Q10 group before the treatment (p=0.013) but not after. The urinary mtDNA/nDNA ratio was 3.05±1.68 and 3.69±2.58 in placebo and Q10 groups, but UTAC was found to be lower in Q10 both before (p=0.006) and after the treatment (p<0.001). The incidence of CI-AKI was 14.40% and the mtDNA/nNDA ratio was similar between CI-AKI and non-CI-AKI patients. In conclusion, Q10 treatment shows no favorable effect on prevention of CI-AKI or a urinary mtDNA/nDNA ratio among diabetic patients.
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