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Data-mining modeling for the prediction of wear on forming-taps in the threading of steel components
Bustillo, Andres,Lopez de Lacalle, Luis N.,Fernandez-Valdivielso, Asier,Santos, Pedro Society for Computational Design and Engineering 2016 Journal of computational design and engineering Vol.3 No.4
An experimental approach is presented for the measurement of wear that is common in the threading of cold-forged steel. In this work, the first objective is to measure wear on various types of roll taps manufactured to tapping holes in microalloyed HR45 steel. Different geometries and levels of wear are tested and measured. Taking their geometry as the critical factor, the types of forming tap with the least wear and the best performance are identified. Abrasive wear was observed on the forming lobes. A higher number of lobes in the chamber zone and around the nominal diameter meant a more uniform load distribution and a more gradual forming process. A second objective is to identify the most accurate data-mining technique for the prediction of form-tap wear. Different data-mining techniques are tested to select the most accurate one: from standard versions such as Multilayer Perceptrons, Support Vector Machines and Regression Trees to the most recent ones such as Rotation Forest ensembles and Iterated Bagging ensembles. The best results were obtained with ensembles of Rotation Forest with unpruned Regression Trees as base regressors that reduced the RMS error of the best-tested baseline technique for the lower length output by 33%, and Additive Regression with unpruned M5P as base regressors that reduced the RMS errors of the linear fit for the upper and total lengths by 25% and 39%, respectively. However, the lower length was statistically more difficult to model in Additive Regression than in Rotation Forest. Rotation Forest with unpruned Regression Trees as base regressors therefore appeared to be the most suitable regressor for the modeling of this industrial problem.
Modality-Dependent Impact of Hallucinations on Low-Frequency Fluctuations in Schizophrenia
Hare, S. M.,Ford, J. M.,Ahmadi, A.,Damaraju, E.,Belger, A.,Bustillo, J.,Lee, H. J.,Mathalon, D. H.,Mueller, B. A.,Preda, A. Oxford University Press 2017 Schizophrenia bulletin Vol.43 No.2
<P>Prior resting-state functional magnetic resonance imaging (fMRI) analyses have identified patterns of functional connectivity associated with hallucinations in schizophrenia (Sz). In this study, we performed an analysis of the mean amplitude of low-frequency fluctuations (ALFF) to compare resting state spontaneous low-frequency fluctuations in patients with Sz who report experiencing hallucinations impacting different sensory modalities. By exploring dynamics across 2 low-frequency passbands (slow-4 and slow-5), we assessed the impact of hallucination modality and frequency range on spatial ALFF variation. Drawing from a sample of Sz and healthy controls studied as part of the Functional Imaging Biomedical Informatics Research Network (FBIRN), we replicated prior findings showing that patients with Sz have decreased ALFF in the posterior brain in comparison to controls. Remarkably, we found that patients that endorsed visual hallucinations did not show this pattern of reduced ALFF in the back of the brain. These patients also had elevated ALFF in the left hippocampus in comparison to patients that endorsed auditory (but not visual) hallucinations. Moreover, left hippocampal ALFF across all the cases was related to reported hallucination severity in both the auditory and visual domains, and not overall positive symptoms. This supports the hypothesis that dynamic changes in the ALFF in the hippocampus underlie severity of hallucinations that impact different sensory modalities.</P>
Disrupted network cross talk, hippocampal dysfunction and hallucinations in schizophrenia
Hare, Stephanie M.,Law, Alicia S.,Ford, Judith M.,Mathalon, Daniel H.,Ahmadi, Aral,Damaraju, Eswar,Bustillo, Juan,Belger, Aysenil,Lee, Hyo Jong,Mueller, Bryon A.,Lim, Kelvin O.,Brown, Gregory G.,Preda Elsevier 2018 Schizophrenia Research Vol.199 No.-
<P><B>Abstract</B></P> <P>Hallucinations characterize schizophrenia, with approximately 59% of patients reporting auditory hallucinations and 27% reporting visual hallucinations. Prior neuroimaging studies suggest that hallucinations are linked to disrupted communication across distributed (sensory, salience-monitoring and subcortical) networks. Yet, our understanding of the neurophysiological mechanisms that underlie auditory and visual hallucinations in schizophrenia remains limited.</P> <P>This study integrates two resting-state functional magnetic resonance imaging (fMRI) analysis methods – amplitudes of low-frequency fluctuations (ALFF) and functional network connectivity (FNC) – to explore the hypotheses that (1) abnormal FNC between salience and sensory (visual/auditory) networks underlies hallucinations in schizophrenia, and (2) disrupted hippocampal oscillations (as measured by hippocampal ALFF) beget changes in FNC linked to hallucinations. Our first hypothesis was supported by the finding that schizophrenia patients reporting hallucinations have higher FNC between the salience network and an associative auditory network relative to healthy controls. Hippocampal ALFF was negatively associated with FNC between primary auditory cortex and the salience network in healthy subjects, but was positively associated with FNC between these networks in patients reporting hallucinations. These findings provide <I>indirect</I> support favoring our second hypothesis. We suggest future studies integrate fMRI with electroencephalogram (EEG) and/or magnetoencephalogram (MEG) methods to <I>directly probe</I> the temporal relation between altered hippocampal <I>oscillations</I> and changes in cross-network functional communication.</P>